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  1. Book ; Thesis: Postpartale Immunglobulintherapie und somatische Entwicklung bei intrauterin transfundierten Neugeborenen mit schwerem Morbus haemolyticus neonatorum

    Eggebrecht, Holger

    1999  

    Author's details vorgelegt von Holger Eggebrecht
    Language German
    Size 107 S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Bonn, Univ., Diss., 1999
    HBZ-ID HT010496975
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Transcatheter aortic valve implantation (TAVI) in Germany: more than 100,000 procedures and now the standard of care for the elderly.

    Eggebrecht, Holger / Mehta, Rajendra H

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2019  Volume 14, Issue 15, Page(s) e1549–e1552

    MeSH term(s) Aged ; Aortic Valve ; Aortic Valve Stenosis ; Germany ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Humans ; Risk Factors ; Standard of Care ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
    Language English
    Publishing date 2019-02-08
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-18-01010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article: Gerinnungsmanagement nach Transkatheter-Aortenklappenimplantation (TAVI)

    Eggebrecht, Holger / Niethammer, Margit / Breitbart, Philipp / Liebetrau, Christoph

    Aktuelle Kardiologie

    2022  Volume 11, Issue 06, Page(s) 551–554

    Abstract: In dieser Übersicht stellen wir die aktuelle Literatur zum Gerinnungsmanagement nach TAVI zusammen. Aus den publizierten Studien ergibt sich für die klinische Praxis, dass direkte orale Antikoagulanzien den Vitamin-K-Antagonisten nicht ... ...

    Abstract In dieser Übersicht stellen wir die aktuelle Literatur zum Gerinnungsmanagement nach TAVI zusammen. Aus den publizierten Studien ergibt sich für die klinische Praxis, dass direkte orale Antikoagulanzien den Vitamin-K-Antagonisten nicht unterlegen sind, wenn aus anderen Gründen (z. B. Vorhofflimmern) eine Antikoagulation nach TAVI erforderlich ist. Die zusätzliche Gabe eines Thrombozytenaggregationshemmers bringt in dieser Konstellation keinen Vorteil. Bei Patienten, die keine Indikation für eine orale Antikoagulation haben, hat sich in vielen Zentren die duale Thrombozytenaggregationshemmung mit ASS und Clopidogrel für 3–6 Monate als Standard etabliert. Die randomisierte POPular TAVI-Studie hat allerdings gezeigt, dass die alleinige ASS-Gabe nach TAVI Blutungskomplikationen reduziert, bei gleicher Sicherheit in der Verhinderung thrombotischer Komplikationen.
    Keywords TAVI ; DOAK ; Antikoagulation ; Thrombose ; TAVI ; DOAC ; anticoagulation ; thrombosis
    Language German
    Publishing date 2022-12-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2654127-0
    ISSN 2193-5211 ; 2193-5203
    ISSN (online) 2193-5211
    ISSN 2193-5203
    DOI 10.1055/a-1893-7462
    Database Thieme publisher's database

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  4. Article: The Role of Bioresorbable Scaffolds in Meeting the Challenges of Bifurcations.

    Schmermund, Axel / Eggebrecht, Holger

    Interventional cardiology (London, England)

    2018  Volume 8, Issue 2, Page(s) 87–89

    Abstract: Side branches are frequently related to periprocedural complications. Considering any side branches >1 millimetres (mm), side branch occlusion or reduced flow may occur in approximately 10 % of interventional procedures. First data indicate that ... ...

    Abstract Side branches are frequently related to periprocedural complications. Considering any side branches >1 millimetres (mm), side branch occlusion or reduced flow may occur in approximately 10 % of interventional procedures. First data indicate that bioresorbable vascular scaffolds (BVS) behave similar compared with modern drug-eluting stents (DES) with regard to compromising or occluding sizeable side branches. Although technically more demanding compared with modern DES, it appears to be feasible to dilate side branches after crossing BVS cells. Preliminary data suggest at least balloon diameters up to 2.5 mm can be used, but safety remains unclear. Instead of kissing balloon dilatation, rather sequential balloon dilatation should be employed. Anecdotic evidence suggests BVS can be used even in relatively complex coronary anatomy, e.g. bifurcations distal to chronic total occlusion. Certainly more data are needed. As of today, BVS offer promise not only for the treatment of simple coronary lesions but also bifurcations. Given successful side branch protection, they might allow for restoring the native coronary anatomy in the sense of
    Language English
    Publishing date 2018-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2813989-6
    ISSN 1756-1485 ; 1756-1477
    ISSN (online) 1756-1485
    ISSN 1756-1477
    DOI 10.15420/icr.2013.8.2.87
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: The Current Situation and the Future of Emergent Cardiac Surgery in TAVI.

    Eggebrecht, Holger / Schmermund, Axel

    Interventional cardiology (London, England)

    2018  Volume 10, Issue 1, Page(s) 55–57

    Abstract: Transcatheter aortic valve implantation (TAVI) has become a beneficial treatment for patients with aortic valve stenosis deemed at high or even prohibitive risk for open surgery. The risk for severe complications is low (ranging between 0.2 % and 1.0 %); ...

    Abstract Transcatheter aortic valve implantation (TAVI) has become a beneficial treatment for patients with aortic valve stenosis deemed at high or even prohibitive risk for open surgery. The risk for severe complications is low (ranging between 0.2 % and 1.0 %); nevertheless, in approximately 1 % of patients emergency cardiac surgery (ECS) is required during TAVI. Aortic injury, embolization of the TAVI prosthesis, and myocardial injury are among the most frequent complications necessitating ECS. Mortality rates of ECS during TAVI are high, ranging between 45 % and 67 %, owing to the comorbid and fragile health status of TAVI patients. Therefore, avoidance of complications appears to be of utmost importance to improve outcomes. This review analysis the current literature in terms of incidence, causes, and outcomes of ECS during TAVI.
    Language English
    Publishing date 2018-03-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2813989-6
    ISSN 1756-1485 ; 1756-1477
    ISSN (online) 1756-1485
    ISSN 1756-1477
    DOI 10.15420/icr.2015.10.1.55
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Novel concept of routine total arterial coronary bypass grafting through a left anterior approach avoiding sternotomy.

    Dörge, Hilmar / Sellin, Christian / Belmenai, Ahmed / Asch, Silke / Eggebrecht, Holger / Schächinger, Volker

    Heart and vessels

    2022  Volume 37, Issue 8, Page(s) 1299–1304

    Abstract: Coronary artery bypass grafting (CABG) via full sternotomy remains a very invasive procedure, often requiring prolonged recovery of the patient. We describe a novel, less invasive approach for totally arterial CABG via a small left anterior thoracotomy ... ...

    Abstract Coronary artery bypass grafting (CABG) via full sternotomy remains a very invasive procedure, often requiring prolonged recovery of the patient. We describe a novel, less invasive approach for totally arterial CABG via a small left anterior thoracotomy in a pilot series of 20 unselected patients. From January to March 2020, 20 consecutive patients (mean age 65.9 ± 9.2 years, 100% male, STS-score: 1.6 ± 2) underwent CABG using only arterial conduits via a small left anterior thoracotomy. Patients were operated on cardiopulmonary bypass with peripheral cannulation and transthoracic aortic cross-clamping. Pulling tapes encircling the great vessels, the arrested empty heart was rotated and moved within the pericardium to enable conventional anastomotic techniques especially on lateral and inferior wall coronary targets. In all patients, left internal mammary artery and radial artery were utilized for bypass with 3.3 ± 0.7 distal coronary anastomoses per patient. Anterior, lateral, and inferior wall territories were revascularized in 100%, 85%, and 70% of patients, respectively. Complete anatomical revascularization was achieved in 95% of patients. ICU stay was 1 day in 17 patients, and 14 of patients left the hospital within 8 days. There was no hospital death, no stroke, no myocardial infarction, and no repeat revascularization. In this pilot series of 20 patients, minimally invasive, totally arterial CABG with avoidance of sternotomy was technically feasible with favorable patient outcomes.
    MeSH term(s) Aged ; Coronary Artery Bypass/adverse effects ; Coronary Artery Bypass/methods ; Female ; Humans ; Male ; Middle Aged ; Minimally Invasive Surgical Procedures/methods ; Sternotomy/adverse effects ; Thoracotomy/methods ; Treatment Outcome
    Language English
    Publishing date 2022-02-05
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 89678-0
    ISSN 1615-2573 ; 0910-8327 ; 0935-736X
    ISSN (online) 1615-2573
    ISSN 0910-8327 ; 0935-736X
    DOI 10.1007/s00380-022-02034-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2049: Show issues Location:
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  7. Article: Verzahnung stationär – ambulant

    Dahm, Johannes B. / Eggebrecht, Holger

    Aktuelle Kardiologie

    2019  Volume 8, Issue 01, Page(s) 38–42

    Abstract: Trotz verschiedenster reformpolitischer Änderungen und Schaffung ausreichender rechtlicher Voraussetzungen konnte sich in Deutschland bisher keine sektorendurchlässige personale und durchgehend verzahnte Patientenversorgung mit sinnvoller ökonomischer ... ...

    Abstract Trotz verschiedenster reformpolitischer Änderungen und Schaffung ausreichender rechtlicher Voraussetzungen konnte sich in Deutschland bisher keine sektorendurchlässige personale und durchgehend verzahnte Patientenversorgung mit sinnvoller ökonomischer Nutzung gemeinsamer Apparate und personeller Ressourcen etablieren. Zum funktionierenden und nachhaltigen Aufbau einer verzahnten Patientenversorgung gehört der Ausbau kooperativer, fachverbindender und interdisziplinärer Praxisstrukturen und Öffnung für neue Strukturen, auch unter Zugrundelegung des neuen Partnerschaftsgesellschaftsgesetzes sowie auf Krankenhausseite die Etablierung einer sektorenübergreifenden Patientenversorgung, bei dem freiberuflich tätige Ärzte aus dem ambulanten Sektor mit Ärzten aus dem Kliniksektor zusammen arbeiten und beide Seiten ambulant als auch stationär tätig sind.
    Keywords sektorenübergreifende Patientenversorgung ; Verzahnung stationär-ambulant ; interconnected patient care ; in-hospital and outpatient care
    Language German
    Publishing date 2019-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2654127-0
    ISSN 2193-5211 ; 2193-5203
    ISSN (online) 2193-5211
    ISSN 2193-5203
    DOI 10.1055/a-0826-2430
    Database Thieme publisher's database

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  8. Article ; Online: Reply to the letter to the editor by Doshi regarding the article "In-hospital outcomes after transcatheter or surgical aortic valve replacement in younger patients less than 75 years old: a propensity-matched comparison".

    Eggebrecht, Holger / Bestehorn, Kurt / Mehta, Rajendra H

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2018  Volume 14, Issue 4, Page(s) e486

    MeSH term(s) Aged ; Aortic Valve ; Aortic Valve Stenosis ; Heart Valve Prosthesis ; Humans ; Propensity Score ; Risk Factors ; Transcatheter Aortic Valve Replacement ; Treatment Outcome
    Language English
    Publishing date 2018-07-20
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJ-D-18-00236R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online ; Thesis: Transfemoraler Aortenklappenersatz bei Patienten mit hochgradiger Aortenklappenstenose in einem Krankenhaus ohne institutionalisierte Herzchirurgie mit externer herzchirurgischer Kooperation

    Lämmer, Johannes [Verfasser] / Eggebrecht, Holger [Akademischer Betreuer]

    2020  

    Author's details Johannes Lämmer ; Betreuer: Holger Eggebrecht
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Duisburg ; Universität Duisburg-Essen
    Publishing place Essen
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Article ; Online: Transcatheter aortic valve implantation (TAVI) in Germany 2008-2014: on its way to standard therapy for aortic valve stenosis in the elderly?

    Eggebrecht, Holger / Mehta, Rajendra H

    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology

    2016  Volume 11, Issue 9, Page(s) 1029–1033

    Abstract: Aims: In Germany, all transcatheter aortic valve implantations (TAVI) and surgical aortic valve replacements (sAVR) are registered within an obligatory quality assurance programme led by the independent AQUA Institute. We have summarised patient and ... ...

    Abstract Aims: In Germany, all transcatheter aortic valve implantations (TAVI) and surgical aortic valve replacements (sAVR) are registered within an obligatory quality assurance programme led by the independent AQUA Institute. We have summarised patient and procedural characteristics, complication and mortality rates as reported in the annual, German language AQUA quality reports, freely accessible online, in order to provide a comprehensive overview of developments between 2008 and 2014.
    Methods and results: Since 2008, a total of 71,927 isolated sAVR and 48,353 TAVI procedures have been performed in Germany. The numbers of sAVR are steadily declining (2008: 11,205; 2014: 9,953). For TAVI, there has been a 20-fold increase since 2008, from 637 to 13,264 procedures in 2014, surpassing the annual numbers of isolated sAVR since 2013. The age profile of TAVI patients has remained unchanged over time (mean age: 80.9 years), with a recent trend towards lower-risk/intermediate-risk patients. TAVI complications are rapidly decreasing (2012: 9.4%; 2014: 3.9%); annular rupture, aortic dissection and coronary occlusions are rare (<0.3%), with fewer patients requiring surgical conversion to sternotomy (2012: 1.2%; 2014: 0.6%). In-hospital mortality after TAVI has halved in 2014 (4.2%) compared with 2008 (10.4%).
    Conclusions: Real-world clinical data from the obligatory quality assurance programme document the rapid adoption of TAVI in Germany, shifting treatment of aortic valve stenosis in the elderly from surgery to a catheter-based approach. Since 2008, similar to what happened with PCIs, complications of TAVI have declined considerably along with the need for emergency cardiac surgery. Most importantly, in-hospital mortality has halved from 2008 to 2014, while mortality for sAVR has remained unchanged.
    MeSH term(s) Age Factors ; Aged ; Aged, 80 and over ; Aortic Valve/physiopathology ; Aortic Valve Stenosis/diagnosis ; Aortic Valve Stenosis/mortality ; Aortic Valve Stenosis/physiopathology ; Aortic Valve Stenosis/therapy ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/mortality ; Cardiac Catheterization/trends ; Female ; Germany ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/mortality ; Heart Valve Prosthesis Implantation/trends ; Hospital Mortality/trends ; Humans ; Male ; Quality Assurance, Health Care/trends ; Registries ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2016-01-22
    Publishing country France
    Document type Journal Article
    ZDB-ID 2457174-X
    ISSN 1969-6213 ; 1774-024X
    ISSN (online) 1969-6213
    ISSN 1774-024X
    DOI 10.4244/EIJY15M09_11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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