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  1. Article ; Online: K-doped CeO

    Portarapillo, Maria / Russo, Danilo / Landi, Gianluca / Luciani, Giuseppina / Di Benedetto, Almerinda

    RSC advances

    2021  Volume 11, Issue 62, Page(s) 39420–39427

    Abstract: Green syngas production is a sustainable energy-development goal. Thermochemical ... ...

    Abstract Green syngas production is a sustainable energy-development goal. Thermochemical H
    Language English
    Publishing date 2021-12-12
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d1ra08315e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: K-doped CeO₂–ZrO₂ for CO₂ thermochemical catalytic splitting

    Portarapillo, Maria / Russo, Danilo / Landi, Gianluca / Luciani, Giuseppina / Di Benedetto, Almerinda

    RSC advances. 2021 Dec. 12, v. 11, no. 62

    2021  

    Abstract: ... of these materials must be improved to allow their use in large scale plants. K-doped systems show good redox ... sites in the investigated catalytic systems and their role at different K contents. Moreover, the model was used to predict ...

    Abstract Green syngas production is a sustainable energy-development goal. Thermochemical H₂O/CO₂ splitting is a very promising sustainable technology allowing the production of H₂ and CO with only oxygen as the by-product. CeO₂–ZrO₂ systems are well known thermochemical splitting catalysts, since they combine stability at high temperature with rapid kinetics and redox cyclability. However, redox performances of these materials must be improved to allow their use in large scale plants. K-doped systems show good redox properties and repeatable performances. In this work, we studied the effect of potassium content on the performances of ceria–zirconia for CO₂ splitting. A kinetic model was developed to get insight into the nature of the catalytic sites. Fitting results confirmed the hypothesis about the existence of two types of redox sites in the investigated catalytic systems and their role at different K contents. Moreover, the model was used to predict the influence of key parameters, such as the process conditions.
    Keywords byproducts ; carbon dioxide ; kinetics ; models ; oxygen ; potassium ; sustainable technology ; synthesis gas ; temperature
    Language English
    Dates of publication 2021-1212
    Size p. 39420-39427.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ISSN 2046-2069
    DOI 10.1039/d1ra08315e
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Surgical management of 2- or 3-part proximal humeral fractures: comparison of plate, nail and K-wires.

    Setaro, N / Rotini, M / Luciani, P / Facco, G / Gigante, A

    Musculoskeletal surgery

    2020  Volume 106, Issue 2, Page(s) 163–167

    Abstract: ... with plate and screws, 53 with intramedullary nailing and 31 with retrograde K-wires. We constituted three ... to results from the patients treated by retrograde K-wires (Group III), while nails showed better functional ... superior results compared to those available with retrograde K-wires. So the nail seems to be a more ...

    Abstract Background: Proximal humeral fractures (PHFs) are fairly common injuries, and their treatment is a challenge. The aim of this study is to compare clinical and functional outcomes of different osteosynthesis techniques.
    Materials and methods: We retrospectively reviewed patients' files and the hospital's digital database between March 2002 and April 2018. We treated surgically 148 patients with 2- and 3-part PHFs: 64 with plate and screws, 53 with intramedullary nailing and 31 with retrograde K-wires. We constituted three groups according to the type of treatment and two subgroups for each according to the number of fragments (Neer II or Neer III). Disabilities of the Arm, Shoulder and Hand (DASH) and Short Form-12 (SF-12) scores were recorded.
    Results: Mean DASH and SF-12 scores both from the group treated with plate (Group I) and the one subjected to intramedullary nailing (Group II) were statistically superior to results from the patients treated by retrograde K-wires (Group III), while nails showed better functional results than the locking plates. In the first two groups, no difference was found between Neer II and III subgroups, while in Group III the DASH scores were significantly better in Neer II subgroup than those in Neer III subgroup. Avascular necrosis was the most frequent cause of revision surgery in Group I (4 cases) where we had 8 cases of reintervention (12.5%). In Group II, the subacromial impingement was the only cause for revision surgery with 3 cases (5.6%).
    Conclusions: Intramedullary nails showed better functional results and a lower complication rate than the locking plates. Both techniques showed superior results compared to those available with retrograde K-wires. So the nail seems to be a more reliable and adequate method for treating 2- and 3-part proximal humeral fractures.
    MeSH term(s) Bone Plates ; Fracture Fixation, Internal ; Fracture Fixation, Intramedullary/methods ; Humans ; Humeral Fractures ; Retrospective Studies ; Shoulder ; Shoulder Fractures/etiology ; Treatment Outcome
    Language English
    Publishing date 2020-11-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2495458-5
    ISSN 2035-5114 ; 2035-5106
    ISSN (online) 2035-5114
    ISSN 2035-5106
    DOI 10.1007/s12306-020-00686-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply to "Reviews of One Anastomosis Gastric Bypass" by K. Mahawar.

    Deitel, Mervyn / Kular, Kuldeepak S / Musella, Mario / Carbajo, Miguel A / Rutledge, Robert / Chowbey, Pradeep / Luque-de-Leon, Enrique / Rheinwalt, Karl P / Luciani, Roger C / Jammu, Gurvinder S / Hargroder, David E / Prasad, Arun

    Obesity surgery

    2017  Volume 27, Issue 4, Page(s) 1058

    Language English
    Publishing date 2017-04
    Publishing country United States
    Document type Letter
    ZDB-ID 1070827-3
    ISSN 1708-0428 ; 0960-8923
    ISSN (online) 1708-0428
    ISSN 0960-8923
    DOI 10.1007/s11695-016-2490-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reply to L.K. Mell et al.

    Ballman, Karla V / Mauer, Murielle / Wedding, Ulrich / Mohile, Supriya G / Muss, Hyman / Extermann, Martine / Luciani, Andrea / Cohen, Harvey Jay / Hurria, Arti / Lichtman, Stuart M / Curigliano, Giuseppe / Wildiers, Hans

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2014  Volume 32, Issue 10, Page(s) 1090–1091

    MeSH term(s) Clinical Trials as Topic ; Geriatrics ; Humans ; Neoplasms/therapy ; Research Design
    Language English
    Publishing date 2014-04-01
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2013.54.5236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Editorial: Mitochondria at the nexus of metabolism, aging, and disease.

    Mallilankaraman, Karthik Babu / Kennedy, Brian K / Sorrentino, Vincenzo / Luciani, Alessandro

    Frontiers in cell and developmental biology

    2024  Volume 11, Page(s) 1356278

    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2737824-X
    ISSN 2296-634X
    ISSN 2296-634X
    DOI 10.3389/fcell.2023.1356278
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Adult self-reported childhood maltreatment types are associated with treatment satisfaction and alcohol relapse in patients with comorbid substance use and mental health disorders.

    Luciani, Karling R / Johal, Priya K / Chao, Thomas / Thiessen, Karina A / Schütz, Christian G

    The American journal on addictions

    2024  

    Abstract: Background and objectives: Individuals with comorbid substance use and mental health disorders (concurrent disorders; CD) report poor treatment outcomes, high prevalence of childhood maltreatment, and mostly negative experiences with treatment. No ... ...

    Abstract Background and objectives: Individuals with comorbid substance use and mental health disorders (concurrent disorders; CD) report poor treatment outcomes, high prevalence of childhood maltreatment, and mostly negative experiences with treatment. No studies to date have examined childhood maltreatment and treatment outcomes in CD. This study investigated self-reported childhood maltreatment as it relates to treatment satisfaction and substance use relapse among CD patients.
    Methods: The 258 CD inpatients completed a self-report questionnaire package, comprising the Childhood Trauma Questionnaire and the Inpatient Consumer Survey (ICS). Childhood maltreatment was assessed according to five subtypes and self-perceived treatment satisfaction was rated across six ICS domains. Psychiatric diagnoses, substance use status and relapse data were retrieved via patient medical charts.
    Results: Emotional neglect was associated with lower ratings across all ICS domains and physical neglect was associated with a lower rating for 'outcome of care'. Childhood sexual abuse was associated with a greater likelihood of alcohol relapse. No other relationships were statistically significant.
    Discussion and conclusions: The presence of childhood neglect (but not abuse) was more associated with overall treatment dissatisfaction, and sexual abuse alone increased the likelihood of alcohol relapse. These findings suggest some early adverse experiences in CD patients may increase negative experiences in treatment while others contribute to the risk of substance use. Broader longitudinal research is needed to examine the trajectory leading to negative outcomes.
    Scientific significance: This is the first study to report differential patterns of association by type of childhood maltreatment on negative outcomes in treatment among CD patients.
    Language English
    Publishing date 2024-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1141440-6
    ISSN 1521-0391 ; 1055-0496
    ISSN (online) 1521-0391
    ISSN 1055-0496
    DOI 10.1111/ajad.13535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Editorial

    Karthik Babu Mallilankaraman / Brian K. Kennedy / Vincenzo Sorrentino / Alessandro Luciani

    Frontiers in Cell and Developmental Biology, Vol

    Mitochondria at the nexus of metabolism, aging, and disease

    2024  Volume 11

    Keywords ageing ; metabolism ; mitochondrial dysfuncion ; mitophagy ; metabolic disease ; dietary intervention ; Biology (General) ; QH301-705.5
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Tracking matricellular protein SPARC in extracellular vesicles as a non-destructive method to evaluate lipid-based antifibrotic treatments.

    Zivko, Cristina / Fuhrmann, Kathrin / Fuhrmann, Gregor / Luciani, Paola

    Communications biology

    2022  Volume 5, Issue 1, Page(s) 1155

    Abstract: Uncovering the complex cellular mechanisms underlying hepatic fibrogenesis could expedite the development of effective treatments and noninvasive diagnosis for liver fibrosis. The biochemical complexity of extracellular vesicles (EVs) and their role in ... ...

    Abstract Uncovering the complex cellular mechanisms underlying hepatic fibrogenesis could expedite the development of effective treatments and noninvasive diagnosis for liver fibrosis. The biochemical complexity of extracellular vesicles (EVs) and their role in intercellular communication make them an attractive tool to look for biomarkers as potential alternative to liver biopsies. We developed a solid set of methods to isolate and characterize EVs from differently treated human hepatic stellate cell (HSC) line LX-2, and we investigated their biological effect onto naïve LX-2, proving that EVs do play an active role in fibrogenesis. We mined our proteomic data for EV-associated proteins whose expression correlated with HSC treatment, choosing the matricellular protein SPARC as proof-of-concept for the feasibility of fluorescence nanoparticle-tracking analysis to determine an EV-based HSCs' fibrogenic phenotype. We thus used EVs to directly evaluate the efficacy of treatment with S80, a polyenylphosphatidylcholines-rich lipid, finding that S80 reduces the relative presence of SPARC-positive EVs. Here we correlated the cellular response to lipid-based antifibrotic treatment to the relative presence of a candidate protein marker associated with the released EVs. Along with providing insights into polyenylphosphatidylcholines treatments, our findings pave the way for precise and less invasive diagnostic analyses of hepatic fibrogenesis.
    MeSH term(s) Humans ; Proteomics ; Hepatic Stellate Cells/metabolism ; Extracellular Vesicles/metabolism ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/metabolism ; Biomarkers/metabolism ; Lipids ; Osteonectin/metabolism
    Chemical Substances Biomarkers ; Lipids ; SPARC protein, human ; Osteonectin
    Language English
    Publishing date 2022-10-30
    Publishing country England
    Document type Journal Article
    ISSN 2399-3642
    ISSN (online) 2399-3642
    DOI 10.1038/s42003-022-04123-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Orthopaedic Research Consortiums: A Review of Scope, Sex and Racial Representation.

    Ozdag, Yagiz / Luciani, A Michael / Foster, Brian K / Baylor, Jessica L / Hayes, Daniel S / Gabelus, Stephanie / Grandizio, Louis C

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55859

    Abstract: Introduction The creation of research groups and consortiums has become more common in all medical and surgical specialities. The purpose of this investigation was to assess and describe collaborative research groups and consortiums within orthopaedic ... ...

    Abstract Introduction The creation of research groups and consortiums has become more common in all medical and surgical specialities. The purpose of this investigation was to assess and describe collaborative research groups and consortiums within orthopaedic surgery. In addition, we aimed to define the demographics of the research consortium members with particular attention to female and minority members. Methods  Journals with a musculoskeletal/orthopaedic focus and a few medical journals were selected to identify articles published by research groups and consortiums. Articles published from 2020 to 2022 were manually reviewed. Bibliographic information, author information and level of evidence (LOE) were recorded. For identified consortium members, sex and race were defined in a binary manner. Results A total of 92 research consortiums were identified. A list of members was identified for 77 groups (83.7%), totalling 2,260 researchers. The remaining group members were not able to be identified due to the lack of information in the included publications, research group websites or after communicating with the corresponding author for respective articles. Most researchers were male (n=1,748, 77.3%) and white (n=1,694, 75%). Orthopaedic surgeons comprised 1,613 (71.4%) identified researchers. The most common fellowship training for orthopaedic surgeons was paediatrics (n=370, 16.4%), trauma (n=266, 11.8%) and sports medicine (n=229, 10.1%). The consortiums published 261 articles: women were lead (first) authors in 23% and senior (last) authors in 11.1%. Non-white researchers were lead authors in 24.5% (n=64) and senior authors in 17.2% (n=45). The most common level of evidence was level 3, accounting for 45.6% (n=119) of all publications. Level 1 evidence accounted for 12.6% (n=33) of published articles. Discussion Representation of women in orthopaedic research consortiums exceeds their representation in almost every orthopaedic professional society. There is less publicly available data to compare the involvement of under-represented minorities (URMs) in research consortiums to general practice. Further investigations should analyse possible avenues in which gender and racial disparity could be improved within orthopaedic surgery research.
    Language English
    Publishing date 2024-03-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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