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  1. Article ; Online: Engaging My Gen Z Class: Teaching with Memes.

    Mendez-Reguera, Aniela / Lopez Cabrera, Mildred Vanessa

    Medical science educator

    2020  Volume 30, Issue 4, Page(s) 1357–1358

    Abstract: Fostering engagement in a traditional setting with Generation Z learners was difficult enough; to do so online, while most educators are battling with technology, poses an even harder challenge amid the pandemic. In an unconventional assignment, students ...

    Abstract Fostering engagement in a traditional setting with Generation Z learners was difficult enough; to do so online, while most educators are battling with technology, poses an even harder challenge amid the pandemic. In an unconventional assignment, students were asked to create an Internet meme to explain any immunology class themes.
    Keywords covid19
    Language English
    Publishing date 2020-09-09
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-020-01078-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Using a digital whiteboard for student engagement in distance education.

    Reguera, Elsa Aniela Mendez / Lopez, Mildred

    Computers & electrical engineering : an international journal

    2021  Volume 93, Page(s) 107268

    Abstract: The COVID-19 pandemic transformed educational processes across different educational levels. As institutions and faculty members effort focused on guaranteeing academic continuity, the challenge was how to translate the learning methodologies applied in ... ...

    Abstract The COVID-19 pandemic transformed educational processes across different educational levels. As institutions and faculty members effort focused on guaranteeing academic continuity, the challenge was how to translate the learning methodologies applied in the classroom to virtual settings. A digital whiteboard was integrated to synchronous class sessions to complement the educational experience. During these sessions, students and teachers interacted to co-construct ideas and socialize learning. The objective of this study was to assess the impact of introducing a digital whiteboard in student engagement. The quantitative approach integrated student's perception through an online survey with 12 items. The results show that the students enjoyed the dynamic(4.56), students believe that the incorporation of digital whiteboard contributed to understanding abstract concepts(4.83), and perceived the resource contributed for class engagement(4.72). The design of educational projects that incorporate these resources translate to active learning dynamics which foster student engagement.
    Language English
    Publishing date 2021-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1501325-X
    ISSN 1879-0755 ; 0045-7906
    ISSN (online) 1879-0755
    ISSN 0045-7906
    DOI 10.1016/j.compeleceng.2021.107268
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Coronabunker: Let's just not talk about 'it'.

    Méndez Reguera, Aniela / López Cabrera, Mildred Vanessa

    Medical education

    2020  Volume 54, Issue 11, Page(s) 1053–1054

    Keywords covid19
    Language English
    Publishing date 2020-09-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.14306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 312: Show issues Location:
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  5. Article ; Online: Pathogenic CCR6+ dendritic cells in the skin lesions of discoid lupus patients: a role for damage-associated molecular patterns.

    Méndez-Reguera, Aniela / Pérez-Montesinos, Gibrán / Alcántara-Hernández, Marcela / Martínez-Estrada, Virginia / Cazarin-Barrientos, Jorge Rafael / Rojas-Espinosa, Oscar / Jurado-Santacruz, Fermín / Huerta-Yepez, Sara / Bonifaz, Laura C / Bonifaz-Alfonzo, Laura

    European journal of dermatology : EJD

    2013  Volume 23, Issue 2, Page(s) 169–182

    Abstract: Background: Discoid lupus erythematosus (DLE) is a cutaneous autoimmune inflammatory disease in which the role of conventional dendritic cells (cDCs) in skin damage has not been evaluated.: Objective: To evaluate the involvement of cDCs in DLE ... ...

    Abstract Background: Discoid lupus erythematosus (DLE) is a cutaneous autoimmune inflammatory disease in which the role of conventional dendritic cells (cDCs) in skin damage has not been evaluated.
    Objective: To evaluate the involvement of cDCs in DLE pathogenesis.
    Material & methods: Skin biopsies from 42 patients with DLE were embedded in paraffin or placed in culture. The dermis was separated and cell suspensions were characterized by flow cytometry.
    Results: We found an increase in cDCs with inflammatory characteristics in the skin of DLE patients, compared with control skins. Interestingly, cDCs from the DLE patients expressed low levels of the inhibitory molecule PD-L1 and showed a high expression of CCR6, which correlated with disease activity. Increased cellular death was observed in the skin of DLE patients compared with control skin and remarkably we found that damage-associated molecular patterns could be responsible for CCR6 expression on cDCs in the skin.
    Conclusions: Our results indicate the presence of pathogenic CCR6+ cDCs in the skin lesions of DLE patients, which could result from in situ phenotypic changes.
    MeSH term(s) Adolescent ; Adult ; Aged ; Apoptosis ; B7-H1 Antigen/metabolism ; CD11c Antigen/analysis ; CD40 Antigens/analysis ; Cell Count ; Cell Movement ; Cells, Cultured ; Dendritic Cells/chemistry ; Dendritic Cells/metabolism ; Female ; Histocompatibility Antigens Class II/analysis ; Humans ; Lupus Erythematosus, Discoid/blood ; Lupus Erythematosus, Discoid/metabolism ; Lupus Erythematosus, Discoid/pathology ; Male ; Middle Aged ; Nitric Oxide Synthase Type II/analysis ; Receptors, CCR6/analysis ; Receptors, CCR6/metabolism ; Skin/chemistry ; Skin/metabolism ; Tumor Necrosis Factor-alpha/analysis ; Young Adult
    Chemical Substances B7-H1 Antigen ; CCR6 protein, human ; CD11c Antigen ; CD274 protein, human ; CD40 Antigens ; Histocompatibility Antigens Class II ; Receptors, CCR6 ; Tumor Necrosis Factor-alpha ; Nitric Oxide Synthase Type II (EC 1.14.13.39)
    Language English
    Publishing date 2013-04-01
    Publishing country France
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2013.1970
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3484: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: O-glycosylation of NnTreg lymphocytes recognized by the Amaranthus leucocarpus lectin.

    Jiménez-Martínez, María C / Lascurain, Ricardo / Méndez-Reguera, Aniela / Estrada-Parra, Sergio / Estrada-García, Iris / Gorocica, Patricia / Martínez-Cairo, Salvador / Zenteno, Edgar / Chávez, Raúl

    Clinical & developmental immunology

    2013  Volume 2013, Page(s) 506807

    Abstract: O-glycosidically-linked glycans have been involved in development, maturation, homing, and immune regulation in T cells. Previous reports indicate that Amaranthus leucocarpus lectin (ALL), specific for glycans containing galactose-N-acetylgalactosamine ... ...

    Abstract O-glycosidically-linked glycans have been involved in development, maturation, homing, and immune regulation in T cells. Previous reports indicate that Amaranthus leucocarpus lectin (ALL), specific for glycans containing galactose-N-acetylgalactosamine and N-acetylgalactosamine, recognizes human naïve CD27(+)CD25(+)CD4(+) T cells. Our aim was to evaluate the phenotype of CD4(+) T cells recognized by ALL in peripheral blood mononuclear cells obtained from healthy volunteers. CD4(+) T cells were isolated by negative selection using magnetic beads-labeled monoclonal antibodies; the expression of T regulatory cell phenotypic markers was assessed on ALL-recognized cells. In addition, IL-4, IL-10, IFN-γ, and TGF-β intracellular production in ALL (+) cells was also evaluated. The analyses of phenotypic markers and intracellular cytokines were performed through flow cytometry. ALL-recognized CD4(+) T cells were mainly CD45RA(+), CCR7(+) cells. Although 52 ± 10% CD25(+)Foxp3(+) cells were positive to ALL, only 34 ± 4% of ALL (+) cells corresponded to CD25(+)Foxp3(-) cells. Intracellular cytokines in freshly obtained ALL (+)CD4(+) T cells exhibited 8% of IL-4, 15% of IL-10, 2% of IFN-γ, and 15% of TGF-β, whereas ALL (-)CD4(+) T cells depicted 1% of IL-4, 2% of IL-10, <1% of IFN-γ, and 6% of TGF-β. Our results show that galactose-N-acetylgalactosamine and N-galactosamine-bearing CD4(+) T cells expressed phenotypic markers of NnTreg cells.
    MeSH term(s) CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/metabolism ; CTLA-4 Antigen/metabolism ; Cytokines/metabolism ; Flow Cytometry ; Forkhead Transcription Factors/metabolism ; Glycoproteins/immunology ; Glycoproteins/metabolism ; Glycosylation ; Humans ; Immunophenotyping ; Interleukin-2 Receptor alpha Subunit/metabolism ; Lymphocyte Activation/immunology ; Lymphocyte Count ; Phenotype ; Plant Lectins/immunology ; Plant Lectins/metabolism ; T-Lymphocytes, Regulatory/immunology ; T-Lymphocytes, Regulatory/metabolism ; Transforming Growth Factor beta/metabolism
    Chemical Substances Amaranthus leucocarpus lectin ; CTLA-4 Antigen ; Cytokines ; FOXP3 protein, human ; Forkhead Transcription Factors ; Glycoproteins ; Interleukin-2 Receptor alpha Subunit ; Plant Lectins ; Transforming Growth Factor beta
    Language English
    Publishing date 2013-09-24
    Publishing country Egypt
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2119646-1
    ISSN 1740-2530 ; 1740-2522
    ISSN (online) 1740-2530
    ISSN 1740-2522
    DOI 10.1155/2013/506807
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3137: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: O-Glycosylation of NnTreg Lymphocytes Recognized by the Amaranthus leucocarpus Lectin

    María C. Jiménez-Martínez / Ricardo Lascurain / Aniela Méndez-Reguera / Sergio Estrada-Parra / Iris Estrada-García / Patricia Gorocica / Salvador Martínez-Cairo / Edgar Zenteno / Raúl Chávez

    Clinical and Developmental Immunology, Vol

    2013  Volume 2013

    Abstract: O-glycosidically-linked glycans have been involved in development, maturation, homing, and immune regulation in T cells. Previous reports indicate that Amaranthus leucocarpus lectin (ALL), specific for glycans containing galactose-N-acetylgalactosamine ... ...

    Abstract O-glycosidically-linked glycans have been involved in development, maturation, homing, and immune regulation in T cells. Previous reports indicate that Amaranthus leucocarpus lectin (ALL), specific for glycans containing galactose-N-acetylgalactosamine and N-acetylgalactosamine, recognizes human naïve CD27+CD25+CD4+ T cells. Our aim was to evaluate the phenotype of CD4+ T cells recognized by ALL in peripheral blood mononuclear cells obtained from healthy volunteers. CD4+ T cells were isolated by negative selection using magnetic beads-labeled monoclonal antibodies; the expression of T regulatory cell phenotypic markers was assessed on ALL-recognized cells. In addition, IL-4, IL-10, IFN-γ, and TGF-β intracellular production in ALL+ cells was also evaluated. The analyses of phenotypic markers and intracellular cytokines were performed through flow cytometry. ALL-recognized CD4+ T cells were mainly CD45RA+, CCR7+ cells. Although 52±10% CD25+Foxp3+ cells were positive to ALL, only 34±4% of ALL+ cells corresponded to CD25+Foxp3− cells. Intracellular cytokines in freshly obtained ALL+CD4+ T cells exhibited 8% of IL-4, 15% of IL-10, 2% of IFN-γ, and 15% of TGF-β, whereas ALL−CD4+ T cells depicted 1% of IL-4, 2% of IL-10, <1% of IFN-γ, and 6% of TGF-β. Our results show that galactose-N-acetylgalactosamine and N-galactosamine-bearing CD4+ T cells expressed phenotypic markers of NnTreg cells.
    Keywords Medicine ; R ; Internal medicine ; RC31-1245 ; Specialties of internal medicine ; RC581-951 ; Immunologic diseases. Allergy ; RC581-607
    Subject code 570
    Language English
    Publishing date 2013-01-01T00:00:00Z
    Publisher Hindawi Publishing Corporation
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Clinical and pathologic factors associated with development of hepatocellular carcinoma in patients with hepatitis virus-related cirrhosis

    Espinosa Daniela / Méndez-Reguera Aniela / Vega-Vega Olynka / Rodríguez-Díaz José / Rosas-Camargo Vanessa / Martínez-Tlahuel Jorge / Gamboa-Domínguez Armando / Arrieta Oscar

    BMC Cancer, Vol 7, Iss Suppl 1, p A

    a long-term follow-up study

    2007  Volume 33

    Keywords Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Oncology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language English
    Publishing date 2007-02-01T00:00:00Z
    Publisher BioMed Central
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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