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  1. Article ; Online: Ternary nanocomposite potentiates the lysophosphatidic acid effect on human osteoblast (MG63) maturation.

    Elkhenany, Hoda / Elkodous, Mohamed Abd / Mansell, Jason Peter

    Nanomedicine (London, England)

    2023  Volume 18, Issue 21, Page(s) 1459–1475

    Abstract: Aim: ...

    Abstract Aim:
    MeSH term(s) Humans ; Alkaline Phosphatase ; Osteoblasts/metabolism ; Nanocomposites ; Cell Differentiation
    Chemical Substances graphene oxide ; lysophosphatidic acid (PG6M3969SG) ; Alkaline Phosphatase (EC 3.1.3.1)
    Language English
    Publishing date 2023-10-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2277839-1
    ISSN 1748-6963 ; 1743-5889
    ISSN (online) 1748-6963
    ISSN 1743-5889
    DOI 10.2217/nnm-2023-0117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6617: Show issues Location:
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  2. Article ; Online: Cocatalyst loaded Al-SrTiO

    Abd Elkodous, M / El-Khawaga, Ahmed M / Abouelela, Marwa Mohamed / Abdel Maksoud, M I A

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 6331

    Abstract: The continued pollution, waste, and unequal distribution of the limited amount of fresh water on earth are pushing the world into water scarcity crisis. Consequently, development of revolutionary, cost-effective, and efficient techniques for water ... ...

    Abstract The continued pollution, waste, and unequal distribution of the limited amount of fresh water on earth are pushing the world into water scarcity crisis. Consequently, development of revolutionary, cost-effective, and efficient techniques for water purification is essential. Herein, molten flux method was used for the preparation of micro-sized Al-doped SrTiO
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-33249-1
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  3. Article ; Online: Engineered nanomaterials as fighters against SARS-CoV-2: The way to control and treat pandemics.

    Abd Elkodous, Mohamed / El-Sayyad, Gharieb S / Abdel-Daim, Mohamed M

    Environmental science and pollution research international

    2020  Volume 28, Issue 30, Page(s) 40409–40415

    Abstract: In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in ... ...

    Abstract In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in controlling and treating COVID-19 through their antiviral and antibacterial potential with suggested action mechanisms indicating the capability of interaction between these nanomaterials and SARS-CoV-2. These nanomaterials might be among the possible and most effective cures against coronavirus.
    MeSH term(s) Antiviral Agents/pharmacology ; COVID-19 ; Humans ; Nanostructures ; Pandemics ; SARS-CoV-2
    Chemical Substances Antiviral Agents
    Keywords covid19
    Language English
    Publishing date 2020-10-17
    Publishing country Germany
    Document type Editorial
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-11032-3
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  4. Article: Engineered nanomaterials as fighters against SARS-CoV-2: The way to control and treat pandemics

    Abd Elkodous, Mohamed / El-Sayyad, Gharieb S. / Abdel-Daim, Mohamed M.

    Environmental science and pollution research. 2021 Aug., v. 28, no. 30

    2021  

    Abstract: In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in ... ...

    Abstract In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in controlling and treating COVID-19 through their antiviral and antibacterial potential with suggested action mechanisms indicating the capability of interaction between these nanomaterials and SARS-CoV-2. These nanomaterials might be among the possible and most effective cures against coronavirus.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; antibacterial properties ; pollution ; research ; viruses
    Language English
    Dates of publication 2021-08
    Size p. 40409-40415.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Editorial
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-020-11032-3
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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  5. Article ; Online: Accelerating wound healing: Unveiling synergistic effects of P25/SWCNT/Ag and P25/rGO/Ag nanocomposites within PRP-gelatin scaffold, highlighting the synergistic antimicrobial activity.

    Gomaa, Salma / Elkodous, Mohamed Abd / El-Sayed, Abeer I M / Tohamy, Hossam / Abou-Ahmed, Howaida / Abdelwahed, Ramadan / Elkhenany, Hoda

    Biotechnology journal

    2023  Volume 19, Issue 1, Page(s) e2300531

    Abstract: Wound healing is a multifaceted biological process requiring innovative strategies to enhance efficiency and counter infections. In this groundbreaking study, we investigate the regenerative potential of platelet-rich plasma (PRP) integrated into a ... ...

    Abstract Wound healing is a multifaceted biological process requiring innovative strategies to enhance efficiency and counter infections. In this groundbreaking study, we investigate the regenerative potential of platelet-rich plasma (PRP) integrated into a gelatin (GLT) scaffold along with nanocomposites of titanium dioxide (TiO2) (P25)/single-walled carbon nanotubes (SWCNTs)/Ag and P25/reduced graphene oxide (rGO)/Ag. Incorporating these advanced materials into the PRP/GLT delivery system aims to optimize the controlled release of growth factors (GFs) and leverage the exceptional properties of nanomaterials for enhanced tissue repair and wound healing outcomes. Antioxidant activity assessment using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity reveals the superior performance of P25/SWCNTs/Ag compared to P25/rGO/Ag. Their synergistic effects are evaluated in conjunction with antibacterial and antifungal antibiotics. Furthermore, the wound healing potential of P25/SWCNTs/Ag and P25/rGO/Ag, combined with PRP/GLT, is examined. Notably, both nanocomposites exhibit promising synergistic effects with gentamicin and fluconazole against pathogenic strains. Significantly, the inclusion of non-activated PRP substantially augments the wound healing efficacy of P25/SWCNTs/Ag on days 3 (p < 0.01) and 15 (p < 0.05). These findings pave the way for advanced wound dressing and therapeutic interventions, capitalizing on the synergistic effects of PRP and nanomaterials, thus ultimately benefiting patients and advancing regenerative medicine.
    MeSH term(s) Humans ; Gelatin ; Nanotubes, Carbon/chemistry ; Wound Healing ; Nanocomposites/chemistry ; Anti-Bacterial Agents/pharmacology ; Platelet-Rich Plasma ; Graphite
    Chemical Substances Gelatin (9000-70-8) ; graphene oxide ; Nanotubes, Carbon ; Anti-Bacterial Agents ; Graphite (7782-42-5)
    Language English
    Publishing date 2023-12-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2221885-3
    ISSN 1860-7314 ; 1860-6768
    ISSN (online) 1860-7314
    ISSN 1860-6768
    DOI 10.1002/biot.202300531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6349: Show issues Location:
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  6. Article ; Online: Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge.

    Elkhenany, Hoda / El-Derby, Azza / Abd Elkodous, Mohamed / Salah, Radwa A / Lotfy, Ahmed / El-Badri, Nagwa

    Stem cell research & therapy

    2022  Volume 13, Issue 1, Page(s) 8

    Abstract: The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It acts as a highly biocompatible natural scaffold and as a source of several types of stem cells and potent growth factors. It also serves as an effective nano-reservoir ... ...

    Abstract The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It acts as a highly biocompatible natural scaffold and as a source of several types of stem cells and potent growth factors. It also serves as an effective nano-reservoir for drug delivery, thanks to its high entrapment properties. Over the past century, the use of the Amnio-M in the clinic has evolved from a simple sheet for topical applications for skin and corneal repair into more advanced forms, such as micronized dehydrated membrane, amniotic cytokine extract, and solubilized powder injections to regenerate muscles, cartilage, and tendons. This review highlights the development of the Amnio-M over the years and the implication of new and emerging nanotechnology to support expanding its use for tissue engineering and clinical applications.
    MeSH term(s) Amnion ; Cartilage ; Regenerative Medicine ; Skin ; Tissue Engineering ; Tissue Scaffolds
    Language English
    Publishing date 2022-01-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2548671-8
    ISSN 1757-6512 ; 1757-6512
    ISSN (online) 1757-6512
    ISSN 1757-6512
    DOI 10.1186/s13287-021-02684-0
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  7. Article ; Online: Merits of photocatalytic and antimicrobial applications of gamma-irradiated Co

    El-Sayyad, Gharieb S / Abd Elkodous, M / El-Khawaga, Ahmed M / Elsayed, Mohamed A / El-Batal, Ahmed I / Gobara, Mohamed

    RSC advances

    2020  Volume 10, Issue 9, Page(s) 5241–5259

    Abstract: In this paper, we report a layer-by-layer approach for the preparation of a concentric recyclable composite ( ... ...

    Abstract In this paper, we report a layer-by-layer approach for the preparation of a concentric recyclable composite (Co
    Language English
    Publishing date 2020-02-03
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/c9ra10505k
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  8. Article: Engineered nanomaterials as fighters against SARS-CoV-2: The way to control and treat pandemics

    Abd Elkodous, Mohamed / El-Sayyad, Gharieb S / Abdel-Daim, Mohamed M

    Abstract: In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in ... ...

    Abstract In this editorial trend, we aim to collect and present recently available data about the characteristics of SARS-CoV-2 virus, severity, infection, replication, diagnosis, and current medications. In addition, we propose the role of nanomaterials in controlling and treating COVID-19 through their antiviral and antibacterial potential with suggested action mechanisms indicating the capability of interaction between these nanomaterials and SARS-CoV-2. These nanomaterials might be among the possible and most effective cures against coronavirus.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #871532
    Database COVID19

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  9. Article ; Online: Enhanced photocatalytic and antimicrobial performance of a multifunctional Cu-loaded nanocomposite under UV light: theoretical and experimental study.

    Abd Elkodous, M / El-Khawaga, Ahmed M / Abdel Maksoud, M I A / El-Sayyad, Gharieb S / Alias, Nurhaswani / Abdelsalam, Hazem / Ibrahim, Medhat A / Elsayed, Mohamed A / Kawamura, Go / Lockman, Zainovia / Tan, Wai Kian / Matsuda, Atsunori

    Nanoscale

    2022  Volume 14, Issue 23, Page(s) 8306–8317

    Abstract: Due to modern industrialization and population growth, access to clean water has become a global challenge. In this study, a metal-semiconductor heterojunction was constructed between Cu NPs and the ... ...

    Abstract Due to modern industrialization and population growth, access to clean water has become a global challenge. In this study, a metal-semiconductor heterojunction was constructed between Cu NPs and the Co
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Catalysis ; Light ; Nanocomposites ; Potassium Permanganate ; Silicon Dioxide ; Titanium/pharmacology ; Ultraviolet Rays ; Water Pollutants, Chemical
    Chemical Substances Anti-Bacterial Agents ; Water Pollutants, Chemical ; Potassium Permanganate (00OT1QX5U4) ; Silicon Dioxide (7631-86-9) ; Titanium (D1JT611TNE)
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d2nr01710e
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  10. Article ; Online: Subacute silica nanoparticle exposure induced oxidative stress and inflammation in rat hippocampus combined with disruption of cholinergic system and behavioral functions.

    Boukholda, Khadija / Gargouri, Brahim / Aouey, Bakhta / Attaai, Abdelraheim / Elkodous, Mohamed Abd / Najimi, Mohamed / Fiebich, Bernd L / Bouchard, Michèle / Fetoui, Hamadi

    NanoImpact

    2021  Volume 24, Page(s) 100358

    Abstract: Increasing environmental exposure to silica nanoparticles (SiNPs) and limited neurotoxicity studies pose a challenge for safety evaluation and management of these materials. This study aimed to explore the adverse effects and underlying mechanisms of ... ...

    Abstract Increasing environmental exposure to silica nanoparticles (SiNPs) and limited neurotoxicity studies pose a challenge for safety evaluation and management of these materials. This study aimed to explore the adverse effects and underlying mechanisms of subacute exposure to SiNPs by the intraperitoneal route on hippocampus function in rats. Data showed that SiNPs induced a significant increase in oxidative/nitrosative stress markers including reactive oxygen species (ROS), malondialdehyde (MDA), protein oxidation (PCO) and nitrite (NO) production accompanied by reduced antioxidant enzyme activity (catalase, superoxide dismutase, and glutathione peroxidase) and decreased glutathione (GSH). Phenotypically, SiNPs exhibited spatial learning and memory impairment in the Morris water maze (MWM) test, a decrease of the discrimination index in the novel object recognition test (NORT) and higher anxiety-like behavior. SiNPs affected the cholinergic system as reflected by reduced acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) activity. In addition, SiNPs significantly increased mRNA expression level of genes related to inflammation (TNF-α, IL-1β, IL-6, and COX-2) and decreased mRNA expression level of genes related to cholinergic system including choline acetyltransferase (ChAT), vesicular acetylcholine transporter (VAChT), AChE, muscarinic acetylcholine receptor M1 (m1AChR) and nicotinic acetylcholine receptors (nAChR). Histopathological results further showed an alteration in the hippocampus of treated animals associated with marked vacuolation in different hippocampus areas. These findings provide new insights into the molecular mechanism of SiNPs-induced hippocampal alterations leading to impairment of cognitive and behavioral functions, and implicating oxidative stress and inflammation in the hippocampus, as well as disruption of cholinergic system.
    MeSH term(s) Acetylcholinesterase/metabolism ; Animals ; Antioxidants/metabolism ; Butyrylcholinesterase/metabolism ; Cholinergic Agents/metabolism ; Hippocampus ; Inflammation/chemically induced ; Nanoparticles/toxicity ; Oxidative Stress ; RNA, Messenger/metabolism ; Rats ; Silicon Dioxide/toxicity
    Chemical Substances Antioxidants ; Cholinergic Agents ; RNA, Messenger ; Silicon Dioxide (7631-86-9) ; Acetylcholinesterase (EC 3.1.1.7) ; Butyrylcholinesterase (EC 3.1.1.8)
    Language English
    Publishing date 2021-09-25
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2452-0748
    ISSN (online) 2452-0748
    DOI 10.1016/j.impact.2021.100358
    Database MEDical Literature Analysis and Retrieval System OnLINE

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