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  1. Article: The Effect of Changes in Employment on Health of Work-Related Injured Workers: A Longitudinal Perspectives.

    Kim, Han-Kyoul / Kim, Kyu-Min / Kim, Jae-Hak / Rhee, Hyun-Sill

    Healthcare (Basel, Switzerland)

    2021  Volume 9, Issue 4

    Abstract: This longitudinal study attempted to identify changes in employment status and overall health status. The participants were workers who had experienced work-related injuries in the past. In this study, we used the Panel Study of Workers' Compensation ... ...

    Abstract This longitudinal study attempted to identify changes in employment status and overall health status. The participants were workers who had experienced work-related injuries in the past. In this study, we used the Panel Study of Workers' Compensation Insurance from 2013 to 2017. This study utilized propensity score matching for a quasi-experimental design study of the first year to exclude the effects of the confounding variables and exclude the effect of employment status, which is the main independent variable. After applying propensity score matching the research subjects totaled 1070. Changes in employment status were found to have a negative effect on overall health status. This raises new implications for existing industrial accident-related support policies. Thus, it is considered that the scope should be expanded from policies related to re-employment of workers after an industrial accident to improving quality of life through maintaining employment from a long-term perspective. The notable point of this study was to apply the PSM methods. By applying PSM, we clearly identified the effect of changes in employment status on health status.
    Language English
    Publishing date 2021-04-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare9040470
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  2. Article ; Online: The Effect of Changes in Employment on Health of Work-Related Injured Workers

    Han-Kyoul Kim / Kyu-Min Kim / Jae-Hak Kim / Hyun-Sill Rhee

    Healthcare, Vol 9, Iss 470, p

    A Longitudinal Perspectives

    2021  Volume 470

    Abstract: This longitudinal study attempted to identify changes in employment status and overall health status. The participants were workers who had experienced work-related injuries in the past. In this study, we used the Panel Study of Workers’ Compensation ... ...

    Abstract This longitudinal study attempted to identify changes in employment status and overall health status. The participants were workers who had experienced work-related injuries in the past. In this study, we used the Panel Study of Workers’ Compensation Insurance from 2013 to 2017. This study utilized propensity score matching for a quasi-experimental design study of the first year to exclude the effects of the confounding variables and exclude the effect of employment status, which is the main independent variable. After applying propensity score matching the research subjects totaled 1070. Changes in employment status were found to have a negative effect on overall health status. This raises new implications for existing industrial accident-related support policies. Thus, it is considered that the scope should be expanded from policies related to re-employment of workers after an industrial accident to improving quality of life through maintaining employment from a long-term perspective. The notable point of this study was to apply the PSM methods. By applying PSM, we clearly identified the effect of changes in employment status on health status.
    Keywords work-related injuries ; occupational injuries ; employment status ; health status ; propensity score matching ; Medicine ; R
    Subject code 331
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Risk factors associated with idiopathic sudden sensorineural hearing loss in pregnant South Korean women: a nationwide population-based study.

    Kim, Hee-Sun / Lee, Kyu-Min / Han, Sung Won / Cho, Geum Joon / Hwang, Han-Sung

    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians

    2021  Volume 35, Issue 25, Page(s) 7389–7394

    Abstract: Objective: Sudden sensorineural hearing loss (SSNHL) is rare in pregnancy and can be attributed to pregnancy-induced changes in hormone levels that increase thrombogenic risk and alter cochlear microcirculation with consequent development of sudden ... ...

    Abstract Objective: Sudden sensorineural hearing loss (SSNHL) is rare in pregnancy and can be attributed to pregnancy-induced changes in hormone levels that increase thrombogenic risk and alter cochlear microcirculation with consequent development of sudden deafness. The study aimed to analyze the risk factors associated with SSNHL in pregnant South Korean.
    Methods: A retrospective study of the incidence and risk factors associated with SSNHL before pregnancy enrolled 401,470 Korean women who delivered between January 2010 and December 2014. All participants underwent a pre-pregnancy national health screening examination through the National Health Insurance Corporation. We investigated the risk factors in 459 pregnant women with sudden sensorineural hearing loss and in 401,011 pregnant women without SSNHL through the pre-pregnancy national health screening examination and adverse perinatal outcome.
    Results: No statistically significant intergroup differences were observed in the maternal age, parity, method of delivery, gestational age at delivery, body mass index, blood pressure, as well as fasting blood glucose and cholesterol levels. After adjusting for maternal age, the pre-pregnancy body mass index was associated with an increased risk of sensorineural hearing loss in pregnancy (adjusted odds ratio 1.52, 95% confidence interval 1.04-2.22). The sensorineural hearing loss did not increase the risk for gestational hypertension, preterm birth (<37 weeks' gestation), small- and large-for-gestational-age infants, postpartum hemorrhage, placenta previa, and placental abruption.
    Conclusion: SSNHL can occur throughout pregnancy and is associated with maternal pre-pregnancy obesity. Notably, it does not increase risks during delivery or cause adverse perinatal outcomes.
    MeSH term(s) Infant ; Female ; Infant, Newborn ; Humans ; Pregnancy ; Hearing Loss, Sudden/etiology ; Hearing Loss, Sudden/complications ; Pregnant Women ; Retrospective Studies ; Premature Birth ; Placenta ; Hearing Loss, Sensorineural/etiology ; Hearing Loss, Sensorineural/complications ; Risk Factors ; Republic of Korea/epidemiology
    Language English
    Publishing date 2021-07-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2077261-0
    ISSN 1476-4954 ; 1057-0802 ; 1476-7058
    ISSN (online) 1476-4954
    ISSN 1057-0802 ; 1476-7058
    DOI 10.1080/14767058.2021.1949443
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  4. Article ; Online: Real-Space and Real-Time Propagation for Correlated Electron-Nuclear Dynamics Based on Exact Factorization.

    Han, Daeho / Ha, Jong-Kwon / Min, Seung Kyu

    Journal of chemical theory and computation

    2023  Volume 19, Issue 8, Page(s) 2186–2197

    Abstract: We present coupled equations of motion for correlated electron-nuclear dynamics for real-space and real-time propagation with a proper electron-nuclear correlation (ENC) from the exact factorization. Since the original ENC term from the exact ... ...

    Abstract We present coupled equations of motion for correlated electron-nuclear dynamics for real-space and real-time propagation with a proper electron-nuclear correlation (ENC) from the exact factorization. Since the original ENC term from the exact factorization is non-Hermitian, the numerical instability arises as we propagate an electronic wave function. In this paper, we propose a Hermitian-type ENC term which depends on the electron density matrix and the nuclear quantum momentum. Moreover, we show that the Hermitian property of the electron-nuclear correlation term can capture quantum (de)coherence with a stable numerical real-space and real-time propagation. As an application, we demonstrate a real-space and real-time propagation of an electronic wave function coupled to trajectory-based nuclear motion for a one-dimensional model Hamiltonian. Our approach can capture nonadiabatic phenomena as well as quantum decoherence in excited state molecular dynamics. In addition, we propose a scheme to extend the current approach to many-body electronic states based on real-time time-dependent density functional theory, testing the nonadiabatic dynamics of a simple molecular system.
    Language English
    Publishing date 2023-04-06
    Publishing country United States
    Document type Journal Article
    ISSN 1549-9626
    ISSN (online) 1549-9626
    DOI 10.1021/acs.jctc.2c00939
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  5. Article ; Online: Fetuin as a potential serum biomarker to detect subclinical shedder of bovine paratuberculosis.

    Park, Hyun-Eui / Park, Jin-Sik / Park, Hong-Tae / Shin, Jeong-Ih / Kim, Kyu-Min / Park, Seo-Rin / Choi, Jeong-Gyu / Jung, Myunghwan / Kang, Hyung-Lyun / Baik, Seung-Chul / Lee, Woo-Kon / Yoo, Han Sang / Shin, Min-Kyoung

    Microbial pathogenesis

    2022  Volume 169, Page(s) 105675

    Abstract: Paratuberculosis (PTB) is a chronic contagious granulomatous enteritis of wild and domestic ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). PTB causes considerable economic losses to the dairy industry through decreased milk ... ...

    Abstract Paratuberculosis (PTB) is a chronic contagious granulomatous enteritis of wild and domestic ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). PTB causes considerable economic losses to the dairy industry through decreased milk production and premature culling. PTB-affected cattle undergo a subclinical stage without clinical signs and initiate fecal shedding of MAP into the environment. Current diagnostic tools have low sensitivity for the detection of subclinical PTB infection. Therefore, alternative diagnostic tools are required to improve the diagnostic sensitivity of subclinical PTB infection. In this study, we performed ELISA for three previously identified host biomarkers (fetuin, alpha-1-acid glycoprotein, and apolipoprotein) and analyzed their diagnostic performance with conventional PTB diagnostic methods. We observed that serum fetuin levels were significantly lowered in the subclinical shedder and clinical shedder groups than in the healthy control group, indicating its potential utility as a diagnostic biomarker for bovine PTB. Also, fetuin showed an excellent discriminatory power with an AUC = 0.949, a sensitivity of 92.6%, and a specificity of 94.4% for the detection of subclinical MAP infection. In conclusion, our results demonstrated that fetuin could be used as a diagnostic biomarker for enhancing the diagnostic sensitivity for the detection of subclinical MAP infections that are difficult to detect based on current diagnostic methods.
    MeSH term(s) Animals ; Asymptomatic Infections ; Biomarkers ; Cattle ; Cattle Diseases/diagnosis ; Cattle Diseases/microbiology ; Feces/microbiology ; Fetuins ; Mycobacterium avium subsp. paratuberculosis ; Paratuberculosis/diagnosis ; Paratuberculosis/microbiology ; alpha-Fetoproteins
    Chemical Substances Biomarkers ; Fetuins ; alpha-Fetoproteins
    Language English
    Publishing date 2022-07-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2022.105675
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  6. Article ; Online: Association between dental caries and adverse pregnancy outcomes.

    Cho, Geum Joon / Kim, So-Youn / Lee, Hoi Chang / Kim, Ho Yeon / Lee, Kyu-Min / Han, Sung Won / Oh, Min-Jeong

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 5309

    Abstract: Poor oral health is not only associated with diabetes and cardiovascular disease but adverse pregnancy outcomes. However the influence of dental caries on pregnancy is unknown. The aim of this study was to evaluate the association between dental caries ... ...

    Abstract Poor oral health is not only associated with diabetes and cardiovascular disease but adverse pregnancy outcomes. However the influence of dental caries on pregnancy is unknown. The aim of this study was to evaluate the association between dental caries and adverse pregnancy outcomes and the effect of treatment for dental caries on adverse pregnancy outcomes. Primiparas who delivered a singleton between January 1, 2010 and December 31, 2014 and underwent both general health examination and oral health examination during a National Korea Health Screening Examination within 1 year of pregnancy were eligible. The data of the women who met the inclusion criteria were linked to the data of their offspring contained within the National Korea Health Screening Program for Infants and Children database. Among 120,622 women who delivered during the study period, 28,623 (23.7%) women had dental caries. Among them, 4,741 (16.6%) women were treated for dental caries after diagnosis. In a multivariable analysis, women with dental caries had an increased risk of delivering large-for-gestational-age infants (odds ratio, 1.15; 95% confidence interval, 1.07, 1.23) compared to those without dental caries. When women with dental caries were divided on the basis of the treatment of dental caries, women with dental caries but no treatment had an increased risk of delivering large-for-gestational-age infants (odds ratio, 1.15; 95% confidence interval, 1.06, 1.24); conversely, there was no increased risk in women with dental caries and treatment compared with those without. Dental caries and its treatment were not associated with preterm birth and preeclampsia. Untreated dental caries was not associated with preterm birth or preeclampsia but with the risk of delivering large-for-gestational-age infants. These whole observation may be attributed to the various characteristics of mothers who develop dental caries are not treated.
    MeSH term(s) Adult ; Dental Caries/complications ; Female ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Small for Gestational Age ; Pregnancy ; Pregnancy Complications/epidemiology ; Pregnancy Outcome ; Premature Birth/epidemiology ; Republic of Korea/epidemiology
    Language English
    Publishing date 2020-03-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-62306-2
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  7. Article: Fetuin as a potential serum biomarker to detect subclinical shedder of bovine paratuberculosis

    Park, Hyun-Eui / Park, Jin-Sik / Park, Hong-Tae / Shin, Jeong-Ih / Kim, Kyu-Min / Park, Seo-Rin / Choi, Jeong-Gyu / Jung, Myunghwan / Kang, Hyung-Lyun / Baik, Seung-Chul / Lee, Woo-Kon / Yoo, Han Sang / Shin, Min-Kyoung

    Microbial pathogenesis. 2022 Aug., v. 169

    2022  

    Abstract: Paratuberculosis (PTB) is a chronic contagious granulomatous enteritis of wild and domestic ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). PTB causes considerable economic losses to the dairy industry through decreased milk ... ...

    Abstract Paratuberculosis (PTB) is a chronic contagious granulomatous enteritis of wild and domestic ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). PTB causes considerable economic losses to the dairy industry through decreased milk production and premature culling. PTB-affected cattle undergo a subclinical stage without clinical signs and initiate fecal shedding of MAP into the environment. Current diagnostic tools have low sensitivity for the detection of subclinical PTB infection. Therefore, alternative diagnostic tools are required to improve the diagnostic sensitivity of subclinical PTB infection. In this study, we performed ELISA for three previously identified host biomarkers (fetuin, alpha-1-acid glycoprotein, and apolipoprotein) and analyzed their diagnostic performance with conventional PTB diagnostic methods. We observed that serum fetuin levels were significantly lowered in the subclinical shedder and clinical shedder groups than in the healthy control group, indicating its potential utility as a diagnostic biomarker for bovine PTB. Also, fetuin showed an excellent discriminatory power with an AUC = 0.949, a sensitivity of 92.6%, and a specificity of 94.4% for the detection of subclinical MAP infection. In conclusion, our results demonstrated that fetuin could be used as a diagnostic biomarker for enhancing the diagnostic sensitivity for the detection of subclinical MAP infections that are difficult to detect based on current diagnostic methods.
    Keywords Mycobacterium avium subsp. paratuberculosis ; biomarkers ; blood serum ; cattle ; dairy industry ; diagnostic sensitivity ; enteritis ; fetuins ; glycoproteins ; milk production ; paratuberculosis ; pathogenesis
    Language English
    Dates of publication 2022-08
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 632772-2
    ISSN 1096-1208 ; 0882-4010
    ISSN (online) 1096-1208
    ISSN 0882-4010
    DOI 10.1016/j.micpath.2022.105675
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  8. Article ; Online: Risk of Adverse Obstetric Outcomes and the Abnormal Growth of Offspring in Women with a History of Thyroid Cancer.

    Cho, Geum Joon / Kim, So-Youn / Lee, Hoi Chang / Lee, Kyu-Min / Han, Sung Won / Oh, Min-Jeong / Woodruff, Teresa K

    Thyroid : official journal of the American Thyroid Association

    2019  Volume 29, Issue 6, Page(s) 879–885

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Cesarean Section ; Databases, Factual ; Female ; Humans ; Infant, Low Birth Weight ; Infant, Newborn ; Pregnancy ; Pregnancy Outcome ; Retrospective Studies ; Thyroid Neoplasms
    Language English
    Publishing date 2019-05-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1086044-7
    ISSN 1557-9077 ; 1050-7256
    ISSN (online) 1557-9077
    ISSN 1050-7256
    DOI 10.1089/thy.2018.0283
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  9. Article ; Online: Analysis of Medication Errors Reported by Community Pharmacists in the Republic of Korea: A Cross-Sectional Study.

    Han, Ju-Hee / Heo, Kyu-Nam / Han, JiMin / Lee, Mo-Se / Kim, Su-Jin / Min, Sangil / Ah, Young-Mi / Lee, Ju-Yeun

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 1

    Abstract: Background and ... ...

    Abstract Background and objectives
    MeSH term(s) Humans ; Cross-Sectional Studies ; Pharmacists ; Medication Errors ; Patient Safety ; Republic of Korea
    Language English
    Publishing date 2023-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59010151
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  10. Article ; Online: Suicide death and other-cause mortality in psychiatric patients: A South Korean study using nationwide claims data.

    Hong, Minha / Lee, Sang Min / Han, Kyu-Man / Kim, Kyoung-Hoon / Paik, Jong-Woo

    Journal of affective disorders

    2024  Volume 352, Page(s) 288–295

    Abstract: Introduction: It is well-known that suicide and excess mortality are high in patients with psychiatric illnesses and this has long been an important issue in the field of mental health. We aim to investigate suicide and other-cause deaths in patients ... ...

    Abstract Introduction: It is well-known that suicide and excess mortality are high in patients with psychiatric illnesses and this has long been an important issue in the field of mental health. We aim to investigate suicide and other-cause deaths in patients with psychiatric illnesses.
    Methods: This retrospective, population-based cohort was based on the National Health Insurance claims data of the first admission with a principal diagnosis of major psychiatric disorder between 2010 and 2011, and followed up to 2020. A total of 95,855 participants were enrolled. Suicide and other-cause mortality were assessed through Log-rank test and Kaplan-Meier curve.
    Results: There were 95,855 patients, with an average age of 48.2 years. The number of suicide deaths and other-cause deaths was 2408 (288.1 per 100,000 person-years) and 15,192 (1817.6 per 100,000 person-years), respectively. The rate of healthcare utilization prior to suicide was 95.0 %, and the rate of utilization prior to one week before suicide was 43.5 %. The risk of suicide was highest in patients with depression, followed by alcohol use disorder, schizophrenia, and bipolar disorder.
    Conclusions: This study revealed various factors related to healthcare utilization associated with suicide and other-cause deaths in psychiatric patients. Educating frontline healthcare professionals, psychiatrists, emergency department personnel, and general practice doctors using such as Gatekeeper program is important to prevent suicides.
    MeSH term(s) Humans ; Middle Aged ; Suicide/psychology ; Retrospective Studies ; Cause of Death ; Schizophrenia ; Republic of Korea/epidemiology
    Language English
    Publishing date 2024-02-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.02.075
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