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  1. Article ; Online: Potentiated early neural responses to fearful faces are not driven by specific face parts.

    Bruchmann, Maximilian / Mertens, Léa / Schindler, Sebastian / Straube, Thomas

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 4613

    Abstract: Prioritized processing of fearful compared to neutral faces is reflected in increased amplitudes of components of the event-related potential (ERP). It is unknown whether specific face parts drive these modulations. Here, we investigated the ... ...

    Abstract Prioritized processing of fearful compared to neutral faces is reflected in increased amplitudes of components of the event-related potential (ERP). It is unknown whether specific face parts drive these modulations. Here, we investigated the contributions of face parts on ERPs to task-irrelevant fearful and neutral faces using an ERP-dependent facial decoding technique and a large sample of participants (N = 83). Classical ERP analyses showed typical and robust increases of N170 and EPN amplitudes by fearful relative to neutral faces. Facial decoding further showed that the absolute amplitude of these components, as well as the P1, was driven by the low-frequency contrast of specific face parts. However, the difference between fearful and neutral faces was not driven by any specific face part, as supported by Bayesian statistics. Furthermore, there were no correlations between trait anxiety and main effects or interactions. These results suggest that increased N170 and EPN amplitudes to task-irrelevant fearful compared to neutral faces are not driven by specific facial regions but represent a holistic face processing effect.
    MeSH term(s) Humans ; Bayes Theorem ; Electroencephalography/methods ; Facial Expression ; Fear/physiology ; Evoked Potentials/physiology ; Emotions/physiology
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-31752-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Dissociating different temporal stages of emotional word processing by feature-based attention.

    Schindler, Sebastian / Vormbrock, Ria / Helming, Hanne / Straube, Thomas

    Scientific reports

    2023  Volume 13, Issue 1, Page(s) 16860

    Abstract: Negative emotional content is prioritized across different stages of information processing as reflected by different components of the event-related potential (ERP). In this preregistered study (N = 40), we investigated how varying the attentional focus ...

    Abstract Negative emotional content is prioritized across different stages of information processing as reflected by different components of the event-related potential (ERP). In this preregistered study (N = 40), we investigated how varying the attentional focus allows us to dissociate the involvement of specific ERP components in the processing of negative and neutral words. Participants had to discriminate the orientation of lines overlaid onto the words, the word type (adjective/noun), or the emotional content (negative/neutral). Thus, attention was either not focused on words (distraction task), non-emotional aspects, or the emotional relevance of words. Regardless of the task, there were no significant differences between negative and neutral words for the P1, N1, or P2 components. In contrast, interactions between emotion and task were observed for the early posterior negativity (EPN) and late positive potential (LPP). EPN differences were absent during the distraction task but were present in the other two tasks. LPP emotion differences were found only when attention was directed to the emotional content of words. Our study adds to the evidence that early ERP components do not reliably separate negative and neutral words. However, results show that mid-latency and late stages of emotion processing are separable by different attention tasks. The EPN represents a stage of attentional enhancement of negative words given sufficient attentional resources. Differential activations during the LPP stage are associated with more elaborative processing of the emotional meaning of words.
    MeSH term(s) Humans ; Electroencephalography ; Word Processing ; Emotions ; Evoked Potentials ; Attention
    Language English
    Publishing date 2023-10-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-023-43794-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Beyond facial expressions: A systematic review on effects of emotional relevance of faces on the N170.

    Schindler, Sebastian / Bruchmann, Maximilian / Straube, Thomas

    Neuroscience and biobehavioral reviews

    2023  Volume 153, Page(s) 105399

    Abstract: The N170 is the most prominent electrophysiological signature of face processing. While facial expressions reliably modulate the N170, there is considerable variance in N170 modulations by other sources of emotional relevance. Therefore, we ... ...

    Abstract The N170 is the most prominent electrophysiological signature of face processing. While facial expressions reliably modulate the N170, there is considerable variance in N170 modulations by other sources of emotional relevance. Therefore, we systematically review and discuss this research area using different methods to manipulate the emotional relevance of inherently neutral faces. These methods were categorized into (1) existing pre-experimental affective person knowledge (e.g., negative attitudes towards outgroup faces), (2) experimentally instructed affective person knowledge (e.g., negative person information), (3) contingency-based affective learning (e.g., fear-conditioning), or (4) the immediate affective context (e.g., emotional information directly preceding the face presentation). For all categories except the immediate affective context category, the majority of studies reported significantly increased N170 amplitudes depending on the emotional relevance of faces. Furthermore, the potentiated N170 was observed across different attention conditions, supporting the role of the emotional relevance of faces on the early prioritized processing of configural facial information, regardless of low-level differences. However, we identified several open research questions and suggest venues for further research.
    MeSH term(s) Humans ; Facial Expression ; Electroencephalography ; Photic Stimulation/methods ; Emotions/physiology ; Fear ; Facial Recognition/physiology ; Evoked Potentials/physiology
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 282464-4
    ISSN 1873-7528 ; 0149-7634
    ISSN (online) 1873-7528
    ISSN 0149-7634
    DOI 10.1016/j.neubiorev.2023.105399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Cannabidiol (CBD) Products for Pain: Ineffective, Expensive, and With Potential Harms.

    Moore, Andrew / Straube, Sebastian / Fisher, Emma / Eccleston, Christopher

    The journal of pain

    2023  Volume 25, Issue 4, Page(s) 833–842

    Abstract: Cannabidiol (CBD) attracts considerable attention for promoting good health and treating various conditions, predominantly pain, often in breach of advertising rules. Examination of available CBD products in North America and Europe demonstrates that CBD ...

    Abstract Cannabidiol (CBD) attracts considerable attention for promoting good health and treating various conditions, predominantly pain, often in breach of advertising rules. Examination of available CBD products in North America and Europe demonstrates that CBD content can vary from none to much more than advertised and that potentially harmful other chemicals are often included. Serious harm is associated with chemicals found in CBD products and reported in children, adults, and the elderly. A 2021 International Association for the Study of Pain task force examined the evidence for cannabinoids and pain but found no trials of CBD. Sixteen CBD randomized trials using pharmaceutical-supplied CBD or making preparations from such a source and with pain as an outcome have been published subsequently. The trials were conducted in 12 different pain states, using 3 oral, topical, and buccal/sublingual administration, with CBD doses between 6 and 1,600 mg, and durations of treatment between a single dose and 12 weeks. Fifteen of the 16 showed no benefit of CBD over placebo. Small clinical trials using verified CBD suggest the drug to be largely benign; while large-scale evidence of safety is lacking, there is growing evidence linking CBD to increased rates of serious adverse events and hepatotoxicity. In January 2023, the Food and Drug Administration (FDA) announced that a new regulatory pathway for CBD was needed. Consumers and health care providers should rely on evidence-based sources of information on CBD, not just advertisements. Current evidence is that CBD for pain is expensive, ineffective, and possibly harmful. PERSPECTIVE: There is no good reason for thinking that CBD relieves pain, but there are good reasons for doubting the contents of CBD products in terms of CBD content and purity.
    MeSH term(s) Adult ; Child ; Humans ; Aged ; Cannabidiol/adverse effects ; Pain/drug therapy ; Pain/chemically induced ; Cannabinoids ; Europe
    Chemical Substances Cannabidiol (19GBJ60SN5) ; Cannabinoids
    Language English
    Publishing date 2023-10-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018789-0
    ISSN 1528-8447 ; 1526-5900
    ISSN (online) 1528-8447
    ISSN 1526-5900
    DOI 10.1016/j.jpain.2023.10.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Johann Sebastian Bach

    Terry, Charles Sanford / Klengel, Alice / Straube, Karl

    eine Lebensgeschichte

    1950  

    Title translation Bach <dt.>
    Author's details Charles Sanford Terry. Mit einem Geleitw. von Karl Straube. [Übertr. von Alice Klengel]
    Language German
    Size 246 S, Mit 33 Bildern, Notenbeisp, 8
    Publisher Evang. Verl. Anst
    Publishing place Berlin
    Document type Book
    Note Lizenzausgabe des Insel-Verlages zu Leipzig
    Database Former special subject collection: coastal and deep sea fishing

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  6. Article ; Online: Narrative bias ("spin") is common in randomised trials and systematic reviews of cannabinoids for pain.

    Moore, Andrew / Karadag, Paige / Fisher, Emma / Crombez, Geert / Straube, Sebastian / Eccleston, Christopher

    Pain

    2024  

    Abstract: Abstract: We define narrative bias as a tendency to interpret information as part of a larger story or pattern, regardless of whether the facts support the full narrative. Narrative bias in title and abstract means that results reported in the title and ...

    Abstract Abstract: We define narrative bias as a tendency to interpret information as part of a larger story or pattern, regardless of whether the facts support the full narrative. Narrative bias in title and abstract means that results reported in the title and abstract of an article are done so in a way that could distort their interpretation and mislead readers who had not read the whole article. Narrative bias is often referred to as "spin." It is prevalent in abstracts of scientific papers and is impactful because abstracts are often the only part of an article read. We found no extant narrative bias instrument suitable for exploring both efficacy and safety statements in randomized trials and systematic reviews of pain. We constructed a 6-point instrument with clear instructions and tested it on randomised trials and systematic reviews of cannabinoids and cannabis-based medicines for pain, with updated searches to April 2021. The instrument detected moderate or severe narrative bias in the title and abstract of 24% (8 of 34) of randomised controlled trials and 17% (11 of 64) of systematic reviews; narrative bias for efficacy and safety occurred equally. There was no significant or meaningful association between narrative bias and study characteristics in correlation or cluster analyses. Bias was always in favour of the experimental cannabinoid or cannabis-based medicine. Put simply, reading title and abstract only could give an incorrect impression of efficacy or safety in about 1 in 5 papers reporting on these products.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193153-2
    ISSN 1872-6623 ; 0304-3959
    ISSN (online) 1872-6623
    ISSN 0304-3959
    DOI 10.1097/j.pain.0000000000003140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: How and when social evaluative feedback is processed in the brain: A systematic review on ERP studies.

    Peters, Antje / Helming, Hanne / Bruchmann, Maximilian / Wiegandt, Anja / Straube, Thomas / Schindler, Sebastian

    Cortex; a journal devoted to the study of the nervous system and behavior

    2024  Volume 173, Page(s) 187–207

    Abstract: Social evaluative feedback informs the receiver of the other's views, which may contain judgments of personality-related traits and/or the level of likability. Such kinds of social evaluative feedback are of particular importance to humans. Event-related ...

    Abstract Social evaluative feedback informs the receiver of the other's views, which may contain judgments of personality-related traits and/or the level of likability. Such kinds of social evaluative feedback are of particular importance to humans. Event-related potentials (ERPs) can directly measure where in the processing stream feedback valence, expectancy, or contextual relevance modulate information processing. This review provides an overview and systematization of studies and early, mid-latency, and late ERP effects. Early effects were inconsistently reported for all factors. Feedback valence effects are more consistently reported for specific mid-latency ERPs (Reward Positivity, RewP, and Early Posterior Negativity, EPN) and late positivities (P3 and Late Positive Potential, LPP). Unexpected feedback consistently increased the Feedback Related Negativity (FRN) and, less consistently, decreased P3 amplitudes. Contextual relevance of the sender (e.g., human vs computer sender) or self-relatedness increased mid-latency to late ERPs. Interactions between valence and other factors were less often found, arising during mid-latency stages, where most consistent interactions showed larger EPN and P3 amplitude differences for valent feedback in a more relevant context. The ERP findings highlight that social evaluative feedback is consistently differentiated during mid-latency processing stages. The review discusses the relevance of findings, possible shortcomings of different experimental designs, and open questions. Furthermore, we suggest concrete venues for future research.
    MeSH term(s) Humans ; Electroencephalography ; Feedback ; Evoked Potentials ; Brain ; Feedback, Psychological ; Reward
    Language English
    Publishing date 2024-02-20
    Publishing country Italy
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 280622-8
    ISSN 1973-8102 ; 0010-9452
    ISSN (online) 1973-8102
    ISSN 0010-9452
    DOI 10.1016/j.cortex.2024.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of perceptual and working memory load on brain responses to task-irrelevant stimuli: Review and implications for future research.

    Brockhoff, Laura / Schindler, Sebastian / Bruchmann, Maximilian / Straube, Thomas

    Neuroscience and biobehavioral reviews

    2022  Volume 135, Page(s) 104580

    Abstract: Load Theory assumes that the extent of processing of task-irrelevant information depends on the level (high vs. low load) and type (perceptual vs. working memory) of task load. In this review, we address the neuroscientific perspective on Load Theory by ... ...

    Abstract Load Theory assumes that the extent of processing of task-irrelevant information depends on the level (high vs. low load) and type (perceptual vs. working memory) of task load. In this review, we address the neuroscientific perspective on Load Theory by a systematic evaluation of neuroimaging and electrophysiological studies, which manipulated perceptual or working memory load and reported brain responses to task-irrelevant unimodal and crossmodal stimuli. Studies show: (1) Load effects can be observed across the whole processing stream from subcortical areas to higher cortical areas, (2) both higher perceptual and working memory load lead to decreased distractor processing, (3) event-related potential studies suggest that load effects occur more reliably the later the ERP component and (4) load effects occur both within and across modalities. Thus, findings are at least partially consistent with assumptions of Load Theory. Based on the reviewed studies and theoretical and methodological considerations, we provide several suggestions, which might help to improve future research in the field.
    MeSH term(s) Attention/physiology ; Brain/physiology ; Evoked Potentials ; Humans ; Memory, Short-Term/physiology
    Language English
    Publishing date 2022-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 282464-4
    ISSN 1873-7528 ; 0149-7634
    ISSN (online) 1873-7528
    ISSN 0149-7634
    DOI 10.1016/j.neubiorev.2022.104580
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Feature-based attention interacts with emotional picture content during mid-latency and late ERP processing stages.

    Schindler, Sebastian / Bruchmann, Maximilian / Straube, Thomas

    Biological psychology

    2022  Volume 170, Page(s) 108310

    Abstract: Several components of the event-related potential (ERP) are amplified by emotional compared to neutral pictures. This study (N = 80) investigated systematically how attention to specific stimulus features influences ERPs to briefly presented (100 ms) ... ...

    Abstract Several components of the event-related potential (ERP) are amplified by emotional compared to neutral pictures. This study (N = 80) investigated systematically how attention to specific stimulus features influences ERPs to briefly presented (100 ms) negative and neutral pictures. Participants had to discriminate either (i) the orientation of overlaid lines, (ii) if the picture content was animate or inanimate, or (iii) if the emotional content was negative or neutral. ERP results showed interactions between the attention task and emotion processing for the early posterior negativity (EPN) and the late positive potential (LPP). For the EPN, attention to distracting perceptual information reduced emotional differences, while at the level of the LPP, emotion effects were selectively amplified when participants attended to the emotional content. These findings reveal the time-dependent effects of feature-based attention tasks on ERPs to emotional pictures.
    MeSH term(s) Electroencephalography ; Emotions ; Evoked Potentials ; Humans ; Photic Stimulation
    Language English
    Publishing date 2022-03-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 185105-6
    ISSN 1873-6246 ; 0301-0511
    ISSN (online) 1873-6246
    ISSN 0301-0511
    DOI 10.1016/j.biopsycho.2022.108310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Obesity and pregnancy

    Briese, Volker / Voigt, Manfred / Straube, Sebastian

    (Pregnancy and infants: medical, psychological and social issues series ; Nova biomedical)

    2010  

    Author's details Volker Briese ; Manfred Voigt and Sebastian Straube
    Series title Pregnancy and infants: medical, psychological and social issues series
    Nova biomedical
    Keywords Pregnancy Complications ; Obesity ; Risk Factors ; Maternal Health Services
    Language English
    Size VI, 184 S. : Ill., graph. Darst.
    Publisher Nova Biomed. Books
    Publishing place New York
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT016124391
    ISBN 978-1-60876-111-1 ; 1-60876-111-8
    Database Catalogue ZB MED Medicine, Health

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