Article ; Online: De novo malignant tumor after renal transplantation
Qiguan Yizhi, Vol 11, Iss 4, Pp 449-
single-center trial
2020 Volume 454
Abstract: Objective To analyze the incidence and risk factors of de novo malignant tumors in renal transplant ... including the basic status, pathological type and incidence rate of patients with de novo malignant tumors ... the risk factors of de novo malignant tumors after renal transplantation were identified. Results ...
Abstract | Objective To analyze the incidence and risk factors of de novo malignant tumors in renal transplant recipients. Methods Clinical data of 1 549 renal transplant recipients were retrospectively analyzed, including the basic status, pathological type and incidence rate of patients with de novo malignant tumors after renal transplantation. The survival situation of these patiensts was assessed. And the risk factors of de novo malignant tumors after renal transplantation were identified. Results The incidence rate of de novo malignant tumors in renal transplant recipients was 3.03%(47/1 549). The 47 recipients were (48±12) years old when undergoing renal transplantation, and they were (55±12) years old when diagnosed malignant tumors. The time interval between transplantation and diagnosis was 66 (36, 100) months. Among the de novo malignant tumors, colorectal cancer was the most common, with a cumulative incidence rate (CIR) of 0.58%. The survival time of 47 recipients with de novo malignant tumors after renal transplantation was 59 (2, 135) months, and the 5-year survival rate was 50%. The recipients with the age > 45 years old when undergoing renal transplantation was a risk factor for de novo malignant tumors after renal transplantation ( P < 0.05). Conclusions The incidence rate of de novo malignant tumors is relatively high in renal transplant recipients. The recipients with the age > 45 years old when undergoing renal transplantation is a risk factor for de novo malignant tumors. |
---|---|
Keywords | renal transplantation ; malignant tumor ; cumulative incidence rate ; risk factor ; colorectal cancer ; survival rate ; Medicine ; R |
Subject code | 616 ; 610 |
Language | Chinese |
Publishing date | 2020-07-01T00:00:00Z |
Publisher | Editorial Department of Organ Transplantation, Periodical Center of the Third Affiliated Hospital of Sun Yat-sen University |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
Full text online
More links
Kategorien
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.