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  1. Article ; Online: Transmission risks of respiratory infectious diseases in various confined spaces: A meta-analysis for future pandemics.

    Moon, Jinyoung / Ryu, Byung-Han

    Environmental research

    2021  Volume 202, Page(s) 111679

    Abstract: Background: If the different transmission risks of respiratory infectious diseases according to the type of confined space and associated factors could be discovered, this kind of information will be an important basis for devising future quarantine ... ...

    Abstract Background: If the different transmission risks of respiratory infectious diseases according to the type of confined space and associated factors could be discovered, this kind of information will be an important basis for devising future quarantine policies. However, no comprehensive systematic review or meta-analysis for this topic exists.
    Objective: The objective of this study is to analyze different transmission risks of respiratory infectious diseases according to the type of confined space. This information will be an important basis for devising future quarantine policies.
    Methods: A medical librarian searched MEDLINE, EMBASE, and the Cochrane Library (until December 01, 2020).
    Results: A total of 147 articles were included. The risk of transmission in all types of confined spaces was approximately 3 times higher than in open space (combined RR, 2.95 (95% CI 2.62-3.33)). Among them, school or workplace showed the highest transmission risk (combined RR, 3.94 (95% CI 3.16-4.90)). Notably, in the sub-analysis for SARS-CoV-2, residential space and airplane were the riskiest space (combined RR, 8.30 (95% CI 3.30-20.90) and 7.30 (95% CI 1.15-46.20), respectively).
    Discussion: Based on the equation of the total number of contacts, the order of transmission according to the type of confined space was calculated. The calculated order was similar to the observed order in this study. The transmission risks in confined spaces can be lowered by reducing each component of the aforementioned equation. However, as seen in the data for SARS-CoV-2, the closure of one type of confined space could increase the population density in another confined space. The authority of infection control should consider this paradox. Appropriate quarantine measures targeted for specific types of confined spaces with a higher risk of transmission, school or workplace for general pathogens, and residential space/airplane for SARS-CoV-2 can reduce the transmission of respiratory infectious diseases.
    MeSH term(s) COVID-19 ; Communicable Diseases/epidemiology ; Confined Spaces ; Humans ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-07-12
    Publishing country Netherlands
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.111679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 726: Show issues Location:
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  2. Article: Transmission risks of respiratory infectious diseases in various confined spaces: A meta-analysis for future pandemics

    Moon, Jinyoung / Ryu, Byung-Han

    Environmental research. 2021 Nov., v. 202

    2021  

    Abstract: If the different transmission risks of respiratory infectious diseases according to the type of confined space and associated factors could be discovered, this kind of information will be an important basis for devising future quarantine policies. ... ...

    Abstract If the different transmission risks of respiratory infectious diseases according to the type of confined space and associated factors could be discovered, this kind of information will be an important basis for devising future quarantine policies. However, no comprehensive systematic review or meta-analysis for this topic exists.The objective of this study is to analyze different transmission risks of respiratory infectious diseases according to the type of confined space. This information will be an important basis for devising future quarantine policies.A medical librarian searched MEDLINE, EMBASE, and the Cochrane Library (until December 01, 2020).A total of 147 articles were included. The risk of transmission in all types of confined spaces was approximately 3 times higher than in open space (combined RR, 2.95 (95% CI 2.62–3.33)). Among them, school or workplace showed the highest transmission risk (combined RR, 3.94 (95% CI 3.16–4.90)). Notably, in the sub-analysis for SARS-CoV-2, residential space and airplane were the riskiest space (combined RR, 8.30 (95% CI 3.30–20.90) and 7.30 (95% CI 1.15–46.20), respectively).Based on the equation of the total number of contacts, the order of transmission according to the type of confined space was calculated. The calculated order was similar to the observed order in this study. The transmission risks in confined spaces can be lowered by reducing each component of the aforementioned equation. However, as seen in the data for SARS-CoV-2, the closure of one type of confined space could increase the population density in another confined space. The authority of infection control should consider this paradox. Appropriate quarantine measures targeted for specific types of confined spaces with a higher risk of transmission, school or workplace for general pathogens, and residential space/airplane for SARS-CoV-2 can reduce the transmission of respiratory infectious diseases.
    Keywords Severe acute respiratory syndrome coronavirus 2 ; disease control ; equations ; librarians ; meta-analysis ; open space ; population density ; quarantine ; research ; risk ; systematic review ; working conditions
    Language English
    Dates of publication 2021-11
    Publishing place Elsevier Inc.
    Document type Article
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2021.111679
    Database NAL-Catalogue (AGRICOLA)

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  3. Article: The Significance of FilmArray Blood Culture Identification Panel (FA-BCID) for Managing Patients with Positive Blood Cultures.

    Widyasari, Kristin / Lee, Seungjun / Cho, Oh-Hyun / Hong, Sun-In / Ryu, Byung-Han / Kim, Sunjoo

    Diagnostics (Basel, Switzerland)

    2023  Volume 13, Issue 21

    Abstract: We analyzed the accuracy and time efficiency of the FilmArray blood culture identification (FA-BCID) panel in identifying the pathogens in positive blood cultures. Two-hundred and seventy-two individuals were randomly assigned as the control ( ...

    Abstract We analyzed the accuracy and time efficiency of the FilmArray blood culture identification (FA-BCID) panel in identifying the pathogens in positive blood cultures. Two-hundred and seventy-two individuals were randomly assigned as the control (
    Language English
    Publishing date 2023-10-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics13213335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The Significance of FilmArray Blood Culture Identification Panel (FA-BCID) for Managing Patients with Positive Blood Cultures

    Kristin Widyasari / Seungjun Lee / Oh-Hyun Cho / Sun-In Hong / Byung-Han Ryu / Sunjoo Kim

    Diagnostics, Vol 13, Iss 21, p

    2023  Volume 3335

    Abstract: We analyzed the accuracy and time efficiency of the FilmArray blood culture identification (FA-BCID) panel in identifying the pathogens in positive blood cultures. Two-hundred and seventy-two individuals were randomly assigned as the control ( n = 212) ... ...

    Abstract We analyzed the accuracy and time efficiency of the FilmArray blood culture identification (FA-BCID) panel in identifying the pathogens in positive blood cultures. Two-hundred and seventy-two individuals were randomly assigned as the control ( n = 212) and FA-BCID ( n = 60) groups participating in this study. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to assess the control group. Meanwhile, the FA-BCID group was evaluated using both FA-BCID and MALDI-TOF, and the results were compared. The identification results from 73% (44/60) of the blood samples demonstrated agreement between FA-BCID and MALDI-TOF. The FA-BCID panel detected mecA genes in seven Staphylococcus species; six cases were confirmed using antimicrobial susceptibility testing. In addition, KPC genes were detected in one Escherichia coli and one Klebsiella pneumoniae , although only the latter corresponded with the result from antimicrobial susceptibility testing. The turnaround time (TAT) for identification through FA-BCID was shorter, with a median of 3.6 [2.4–4.6] hours ( p < 0.05). No significant differences in the clinical and microbial outcomes following the ASP were observed between FA-BCID and MALDI-TOF. These results suggest that the FA-BCID panel provides an identification result that is as reliable as that provided by the routine identification procedure but with shorter TAT; thus, the FA-BCID method is considered an effective and beneficial method for therapeutic decision making and the improvement of the ASP for patients with bloodstream infection.
    Keywords blood culture ; pathogen identification ; antimicrobial stewardship program ; FA-BCID ; MALDI-TOF ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article: Multisystem Inflammatory Syndrome in Adults in an 80-Year-Old Korean Woman after COVID-19: A Case Report.

    Lee, Dain / Kwon, Sungmoon / Kim, Hyoungkwang / Lee, Ju Young / Ryu, Byung-Han

    Infection & chemotherapy

    2022  Volume 55, Issue 1, Page(s) 116–120

    Abstract: Multisystem inflammatory syndrome in adults (MIS-A) is a rare sequelae after coronavirus disease 2019 (COVID-19) that is characterized by fever as well as cardiovascular and gastrointestinal disorders. We present the case of an 80-year-old Korean woman ... ...

    Abstract Multisystem inflammatory syndrome in adults (MIS-A) is a rare sequelae after coronavirus disease 2019 (COVID-19) that is characterized by fever as well as cardiovascular and gastrointestinal disorders. We present the case of an 80-year-old Korean woman with MIS-A who experienced febrile sensations, dyspnea, and whole body pain for 7 weeks after being diagnosed with COVID-19. Initial evaluation revealed heart failure, left pleurisy, and sensory neuropathy, but no evidence of infectious diseases was found. Her symptoms improved quickly after starting systemic glucocorticoid therapy, and inflammatory marker levels decreased. When treating patients with fever after COVID-19, it is critical to suspect MIS-A as one of the differential diagnoses for timely diagnosis and treatment.
    Language English
    Publishing date 2022-12-08
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2022.0115
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Real World Experience with Regdanvimab Treatment of Mild-to-Moderate Coronavirus Disease-19 in a COVID-19 Designated Hospital of Korea.

    Hong, Sun In / Ryu, Byung-Han / Hong, Kyung-Wook / Bae, In-Gyu / Cho, Oh-Hyun

    Infection & chemotherapy

    2022  Volume 54, Issue 1, Page(s) 114–124

    Abstract: Background: Real-world clinical data concerning regdanvimab, a monoclonal antibody treatment for patients with mild-to-moderate coronavirus disease 2019 (COVID-19), are urgently needed. Here, we describe our experience with regdanvimab.: Materials and ...

    Abstract Background: Real-world clinical data concerning regdanvimab, a monoclonal antibody treatment for patients with mild-to-moderate coronavirus disease 2019 (COVID-19), are urgently needed. Here, we describe our experience with regdanvimab.
    Materials and methods: This retrospective cohort study enrolled high-risk adults with mild-to-moderate COVID-19 who were admitted to a dedicated COVID-19 hospital in Korea from March to September 2021. We used multiple logistic regression and propensity score-matching to compare the outcomes of patients who did or did not receive regdanvimab. The primary outcome was in-hospital progression to severe or critical status, or death.
    Results: Of 586 patients eligible for regdanvimab, 256 patients who received regdanvimab and 251 untreated patients were included. The median age was 66 years and 47.5% were men. The most common underlying illnesses were hypertension (53.8%) and diabetes (36.9%). Patients were admitted to the hospital at a median of 2 days after symptom onset; regdanvimab was administered at a median of 3 days after symptom onset. Multivariate analysis indicated that regdanvimab significantly reduced the risk of disease progression during hospitalization [odds ratio (OR): 0.285; 95% confidence interval (CI): 0.144 - 0.564]. In a 1:1 propensity score-matched cohort (172 patients in either group), regdanvimab also decreased the risk of progression (OR: 0.162; 95% CI: 0.068 - 0.386).
    Conclusion: In high-risk patients with mild-to-moderate COVID-19, regdanvimab decreased the risk of progression to severe COVID-19.
    Language English
    Publishing date 2022-05-09
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2573798-3
    ISSN 2093-2340
    ISSN 2093-2340
    DOI 10.3947/ic.2021.0143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Environmental contamination of SARS-CoV-2 during the COVID-19 outbreak in South Korea.

    Ryu, Byung-Han / Cho, Younghwa / Cho, Oh-Hyun / Hong, Sun In / Kim, Sunjoo / Lee, Seungjun

    American journal of infection control

    2020  Volume 48, Issue 8, Page(s) 875–879

    Abstract: Objectives: Although contact precaution is generally recommended in situations where coronavirus disease 2019 (COVID-19) is suspected, there is limited evidence on environmental contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV- ... ...

    Abstract Objectives: Although contact precaution is generally recommended in situations where coronavirus disease 2019 (COVID-19) is suspected, there is limited evidence on environmental contamination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therefore, we conducted environmental surveillance on SARS-CoV-2 contamination in 2 different healthcare settings.
    Methods: Viral contamination was investigated on the environment of 2 hospitals that had admitted 13 COVID-19 patients. In hospital A, 5 patients with pneumonia occupied negative pressure rooms. In hospital B, 8 asymptomatic patients shared 2 common 4-bed rooms. Most rooms were poorly cleaned or disinfected. Environmental swab were collected from inside and outside the rooms and were tested using real-time RT-PCR for the detection of SARS-CoV-2.
    Results: In hospital A, SARS-CoV-2 was detected in 10 of 57 (17.5%) samples from inside the rooms including the Ambu bag and infusion pump. Two samples obtained at more than 2 m from the patients showed positive results. In hospital B, 3 of 22 (13.6%) samples from inside the rooms were positive. Areas outside the rooms, such as the anteroom, corridor, and nursing station, were all negative in both hospitals.
    Conclusions: Hospital surfaces surrounding patients were contaminated by SARS-CoV-2. Our findings support the value of strict contact precaution, routine cleaning, and disinfection in the management of COVID-19 patients.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/transmission ; Coronavirus Infections/virology ; Disease Outbreaks/prevention & control ; Disinfection/methods ; Environmental Pollution/analysis ; Hospitals ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/transmission ; Pneumonia, Viral/virology ; Real-Time Polymerase Chain Reaction/methods ; Republic of Korea/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2020.05.027
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  8. Article ; Online: Features of COVID-19 Among Children and Adolescents Without Risk Factors Before and After the Delta Variant Outbreak in South Korea.

    Ryu, Byung-Han / Hong, Sun In / Lim, Su Jin / Cho, Younghwa / Hong, Kyung-Wook / Bae, In-Gyu / Cho, Oh-Hyun

    The Pediatric infectious disease journal

    2021  Volume 41, Issue 1, Page(s) e34–e35

    MeSH term(s) Adolescent ; COVID-19/epidemiology ; COVID-19/physiopathology ; COVID-19/virology ; Child ; Disease Outbreaks ; Female ; Hospitals ; Humans ; Male ; Republic of Korea/epidemiology ; Risk Factors ; SARS-CoV-2
    Language English
    Publishing date 2021-11-16
    Publishing country United States
    Document type Letter
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003394
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  9. Article ; Online: Comparison of the clinical characteristics and outcomes of bloodstream infections caused by

    Hong, Kyung-Wook / Cheon, Yun-Hong / Moon, Kyunglan / Hong, Sun In / Ryu, Byung-Han / Cho, Oh-Hyun / Bae, In-Gyu

    Infectious diseases (London, England)

    2020  Volume 52, Issue 7, Page(s) 489–497

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacteremia/drug therapy ; Bacteremia/epidemiology ; Humans ; Klebsiella Infections/drug therapy ; Klebsiella Infections/epidemiology ; Klebsiella pneumoniae ; Retrospective Studies ; Sepsis/drug therapy
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2020-05-02
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2839775-7
    ISSN 2374-4243 ; 2374-4235
    ISSN (online) 2374-4243
    ISSN 2374-4235
    DOI 10.1080/23744235.2020.1758764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Environmental contamination of SARS-CoV-2 during the COVID-19 outbreak in South Korea

    Ryu, Byung-Han / Cho, Younghwa / Cho, Oh-Hyun / Hong, Sun In / Kim, Sunjoo / Lee, Seungjun

    American Journal of Infection Control

    2020  Volume 48, Issue 8, Page(s) 875–879

    Keywords Public Health, Environmental and Occupational Health ; Health Policy ; Epidemiology ; Infectious Diseases ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 392362-9
    ISSN 1527-3296 ; 0196-6553
    ISSN (online) 1527-3296
    ISSN 0196-6553
    DOI 10.1016/j.ajic.2020.05.027
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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