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Article ; Online: Investigating the Effect of Educational Intervention on Knowledge, Attitude, and Practice of Housewives in Dastja Village, Iran, in the Field of Waste Recycling

Yadollah Haji-Heydari / Seyedeh Maryam Sharafi / Amir Hossein Nafez

تحقیقات نظام سلامت, Vol 19, Iss 3, Pp 249-

2023 Volume 256

Abstract: Background: Increasing awareness and creating culture in the field of waste management can be a solution to this important environmental issue. The purpose of this study was to determine the effect of educational intervention on knowledge, attitude, and ... ...

Abstract	Background: Increasing awareness and creating culture in the field of waste management can be a solution to this important environmental issue. The purpose of this study was to determine the effect of educational intervention on knowledge, attitude, and practice (KAP) of housewives in Dastja Village of Isfahan Province, Iran, in the field of recycling in 2021. Methods: In this descriptive-interventional study, which was conducted in a cross-sectional way, 60 housewives were selected by systematic random method and completed the KAP questionnaire towards recycling. Then, education related to recycling was presented to the target group, including 3 face-to-face sessions of 40 minutes and one hour of virtual education. The questionnaire was completed again after two months. One-way analysis of variance (ANOVA), independent t-test, and Pearson's correlation test were used to analyze the data. Findings: The average age of the investigated women in the target and control groups was 34.9 ± 9.6 and 36.4 ± 9.2, respectively. After the educational intervention, the level of awareness change in poor, medium, and good groups was -34.69%, +7.72%, and +26.97%, respectively. Besides, the rate of change of attitude scores in poor, medium, and good groups was -11.29%, -12.33%, and +23.62%, respectively. In the practice section, change values in the poor, medium, and good groups were -19.98%, -9.99%, and +30.06%, respectively. Conclusion: Considering the significant improvements in KAP of housewives in Dastja Village after training, by including the education while cooperating and coordinating with the village council and officials in order to develop recycling in rural areas, important steps can be taken and good results can be achieved.
Keywords	recycling ; education ; knowledge ; attitude ; practice ; solid waste ; Environmental technology. Sanitary engineering ; TD1-1066 ; Medicine ; R ; Medicine (General) ; R5-920
Subject code	390
Language	Persian
Publishing date	2023-10-01T00:00:00Z
Publisher	Vesnu Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effect of Hydatid Cyst Antigens Polyspecific Antisera on Breast Cancer Cells (4T1) Growth in Cell Culture Medium

Hossein Yousofi Darani / Seyedeh Maryam Sharafi

International Journal of Environmental Health Engineering, Vol 11, Iss 1, Pp 15-

2022 Volume 15

Abstract: Aim: Hydatid cyst is the Echinococcus granulosus larvae stage and is responsible for echinococcosis. Anticancer effects of hydatid cyst have been shown in human population, experimental animals, and in vitro works. However, the mechanisms of this ... ...

Abstract	Aim: Hydatid cyst is the Echinococcus granulosus larvae stage and is responsible for echinococcosis. Anticancer effects of hydatid cyst have been shown in human population, experimental animals, and in vitro works. However, the mechanisms of this anticancer activity are not clarified. Hence, in this work, the effect of antisera raised against hydatid cyst antigens on the growth of breast cancer cells has been investigated. Materials and Methods: In this experimental study, the various hydatid cyst antigens were prepared. To raise antisera, each of the hydatid cyst antigens (hydatid cyst fluid, germinal and laminated, protoscolex, and excretory-secretory [ES]) and toxoplasma trophozoite were injections to rabbits. The production of specific antibodies in rabbits determinate by enzyme-linked immunoassay, and then, the rabbit's blood was taken, and their sera isolated under the hood in sterile conditions. Before use, all antisera were inactivated at 56°C for half an hour and also placed under ultraviolet light for 20 min to disinfect. Breast cancer cells in the culture medium were purchased from the Pasteur Institute of Iran and growth in CO2 incubator in the Roswell Park Memorial Institute (RPMI) medium. After appropriate, the cells were counted and divided equally in eight-cell culture flasks and treated with different antisera of hydatid cyst. After 32-h incubation, the number of live cells was counted by trypan blue methods and compared with control groups. Results: Based on the results of this research, the difference between the number of live cells after treatment with antisera against hydatid cyst fluid, toxoplasma trophozoite, and ES antigen was significantly different from number of cells in flask treated with normal rabbit serum. Conclusion: In conclusion, due to the presence of common antigens between parasites and cancer, probably antibodies produced against hydatid cyst antigens may affect the growth of cells in the culture media.
Keywords	breast cancer cell (4t) ; hydatid cyst ; polyspecific antiserum ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental engineering ; TA170-171 ; Environmental sciences ; GE1-350
Subject code	616
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Biomonitoring of organochlorine pesticides and cancer survival: a population-based study

Kiyani, Raziyeh / Dehdashti, Bahare / Heidari, Zahra / Sharafi, Seyedeh Maryam / Mahmoodzadeh, Mehdi / Amin, Mohammad Mehdi

Environ Sci Pollut Res. 2023 Mar., v. 30, no. 13 p.37357-37369

2023

Abstract: Organochlorine pesticides (OCPs) are endocrine-disrupting chemicals (EDCs) that even at very low levels can cause cancer by increasing the activity of tumor cells and suppressing the immune system. There is also little information on OCPs and survival ... ...

Abstract	Organochlorine pesticides (OCPs) are endocrine-disrupting chemicals (EDCs) that even at very low levels can cause cancer by increasing the activity of tumor cells and suppressing the immune system. There is also little information on OCPs and survival after diagnosis. The aim of this study was to monitor the concentration of OCPs in the blood serum of cancer patients and its relationship with their socio-demographic characteristics and ultimately that impact on survival time and hazard ratio (HR). This cross-sectional study included 89 diagnosed patients with cancer in Isfahan, Iran. 12 types of OCPs were measured in serum by gas chromatography (7GC) with an electron capture detector and equipped with mass spectrometer (MS). Also, participants’ questionnaire was completed to collect information. T-test, ANOVA, and Chi-square tests were used to evaluate the association between serum levels of OCPs and quantitative and qualitative information of patients. Survival analysis was also examined based on Kaplan–Meier method, log-rank test, and Cox model. The mean of total OCPs in patients’ serum was calculated to be 1.82 ± 1.36 μg/L. Concentration of 2,4′ DDE had a significant relationship with body mass index (BMI) (kg/m²) (P < 0.05). In addition, gender revealed a significant correlation in estimating survival time (P < 0.05). Non-exposure to OCPs showed a positive effect on increasing the life expectancy of patients. Lindane and endosulfan increased the risk of death by 16% and 37%, respectively, with insignificant P value (P > 0.05). The findings of the present study showed adverse effects of OCPs on patients’ survival time and increased mortality of HR. Moreover, as the first research conducted in the study area, it is suggested management of environmental, individual and social factors that could be influenced the biological accumulation of OCPs in humans and cause health promotion.
Keywords	blood serum ; body mass index ; chlorinated hydrocarbons ; cross-sectional studies ; death ; endosulfan ; environmental monitoring ; gas chromatography ; gender ; hazard ratio ; health promotion ; immune system ; lindane ; longevity ; models ; mortality ; neoplasms ; questionnaires ; risk ; spectrometers ; t-test ; Iran
Language	English
Dates of publication	2023-03
Size	p. 37357-37369.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-24855-z
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Biomonitoring of organochlorine pesticides and cancer survival: a population-based study.

Kiyani, Raziyeh / Dehdashti, Bahare / Heidari, Zahra / Sharafi, Seyedeh Maryam / Mahmoodzadeh, Mehdi / Amin, Mohammad Mehdi

Environmental science and pollution research international

2022 Volume 30, Issue 13, Page(s) 37357–37369

Abstract	Organochlorine pesticides (OCPs) are endocrine-disrupting chemicals (EDCs) that even at very low levels can cause cancer by increasing the activity of tumor cells and suppressing the immune system. There is also little information on OCPs and survival after diagnosis. The aim of this study was to monitor the concentration of OCPs in the blood serum of cancer patients and its relationship with their socio-demographic characteristics and ultimately that impact on survival time and hazard ratio (HR). This cross-sectional study included 89 diagnosed patients with cancer in Isfahan, Iran. 12 types of OCPs were measured in serum by gas chromatography (7GC) with an electron capture detector and equipped with mass spectrometer (MS). Also, participants' questionnaire was completed to collect information. T-test, ANOVA, and Chi-square tests were used to evaluate the association between serum levels of OCPs and quantitative and qualitative information of patients. Survival analysis was also examined based on Kaplan-Meier method, log-rank test, and Cox model. The mean of total OCPs in patients' serum was calculated to be 1.82 ± 1.36 μg/L. Concentration of 2,4' DDE had a significant relationship with body mass index (BMI) (kg/m
MeSH term(s)	Humans ; Biological Monitoring ; Cross-Sectional Studies ; Environmental Monitoring ; Pesticides/analysis ; Hydrocarbons, Chlorinated/analysis ; Neoplasms
Chemical Substances	Pesticides ; Hydrocarbons, Chlorinated
Language	English
Publishing date	2022-12-26
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-24855-z
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Article ; Online: Environmental disinfection against COVID-19 in different areas of health care facilities: a review.

Sharafi, Seyedeh Maryam / Ebrahimpour, Karim / Nafez, Amirhossein

Reviews on environmental health

2020 Volume 36, Issue 2, Page(s) 193–198

Abstract: The coronavirus disease 2019 (COVID-19) originated in bats and human-to-human transmission through respiratory droplets and contact with surfaces of infected aerosol are the main ways of transmitting this virus. Until now, there is no effective ... ...

Abstract	The coronavirus disease 2019 (COVID-19) originated in bats and human-to-human transmission through respiratory droplets and contact with surfaces of infected aerosol are the main ways of transmitting this virus. Until now, there is no effective pharmaceutical treatment; conclusively it is important to evaluate the types of applied disinfectants in different areas against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), the virus that causes COVID-19. The aim of this review was to summarize the information about environmental disinfection for preventing of COVID-19. We performed a review of the science direct database to find articles providing information on disinfection used for SARS-CoV-2. The extracted results were given the original data on inactivation coronaviruses by disinfectants in different places of health care facilities. The final search recognized that five groups of disinfectants include: chlorine containing disinfectants, alcohol, UV irradiation, Hydrogen peroxide, and other disinfectant were used against SARS-CoV-2 in different environments. Among these groups, bleach (chlorine containing disinfectants) has the most applicability. Also, in many studies by using disinfectants with 62-71% ethanol can reduce coronavirus in contaminated areas. Furthermore, after the using of operating room for COVID-19 patients, hydrogen peroxide and UV irradiation should be used for 24 h before it can be used again. The povidone-iodine or the chlorhexidine, could be recommended when there is a risk of SARS-CoV-2 contamination especially for open wounds. According to the different studies on SARS-CoV-2 disinfection, because of the SARS-CoV-2 can remain in the air and on surfaces, as well as observing individual disinfection guidelines in different hospital areas, disinfection of surfaces is necessary to decrease SARS-CoV-2 spreading. Moreover, the most suggested disinfectants have been limited to bleach and alcohol, it's better to be considered the potential of other disinfectants in different areas.
MeSH term(s)	COVID-19 ; Delivery of Health Care ; Disinfectants ; Disinfection ; Humans ; Respiratory Aerosols and Droplets ; SARS-CoV-2
Chemical Substances	Disinfectants
Keywords	covid19
Language	English
Publishing date	2020-08-26
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	184450-7
ISSN	2191-0308 ; 0048-7562 ; 0048-7554
ISSN (online)	2191-0308
ISSN	0048-7562 ; 0048-7554
DOI	10.1515/reveh-2020-0075
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Article ; Online: Effect of Vitamin D Supplementation on Serum 25-Hydroxyvitamin D and Homeostatic Model of Insulin Resistance Levels in Healthy Pregnancy: A Systematic Review and Meta-Analysis.

Sharafi, Seyedeh Maryam / Yazdi, Maryam / Goodarzi-Khoigani, Masoomeh / Kelishadi, Roya

Iranian journal of medical sciences

2020 Volume 48, Issue 1, Page(s) 4–12

Abstract: Background: Progressive insulin resistance is a physiological condition during pregnancy that can lead to gestational diabetes. Given the association between low blood vitamin D levels and insulin resistance, the present meta-analysis evaluated the ... ...

Abstract	Background: Progressive insulin resistance is a physiological condition during pregnancy that can lead to gestational diabetes. Given the association between low blood vitamin D levels and insulin resistance, the present meta-analysis evaluated the effect of vitamin D supplementation on serum 25-hydroxyvitamin D (25[OH]D) and the homeostatic model of insulin resistance (HOMA-IR) levels in non-diabetic pregnant women. Methods: A comprehensive literature search was conducted using electronic databases and gateways such as Cochrane Library, Medline, Google Scholar, Science Direct, Web of Sciences, Embase, and Scopus. Articles up to 2020 in both English and Persian were included in the study. The effect of vitamin D supplementation on 25(OH)D and HOMA-IR was determined based on the differences in mean changes from baseline to post-intervention. Weighted mean and 95% confidence intervals (CI) were pooled using a random-effects model. Data were analyzed using STATA software. Results: Four studies, including six trials with 380 participants, reported that vitamin D supplementation increased 25(OH)D (mean change: 13.72, 95% CI: 7.28-20.17) and decreased HOMA-IR (mean change: 1.46, 95% CI: 0.56-2.37) levels compared with the placebo group. A high weekly dose of vitamin D further reduced HOMA-IR levels (adjusted R Conclusion: Vitamin D supplementation increased 25(OH)D and decreased HOMA-IR levels in non-diabetic pregnant women. Vitamin D in high doses further reduced HOMA-IR, but did not affect 25(OH)D concentrations.
MeSH term(s)	Female ; Pregnancy ; Humans ; Insulin Resistance/physiology ; Dietary Supplements ; Blood Glucose ; Vitamin D/pharmacology ; Vitamin D/therapeutic use ; Vitamins/therapeutic use ; Calcifediol
Chemical Substances	25-hydroxyvitamin D (A288AR3C9H) ; Blood Glucose ; Vitamin D (1406-16-2) ; Vitamins ; Calcifediol (P6YZ13C99Q)
Language	English
Publishing date	2020-04-23
Publishing country	Iran
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	603872-4
ISSN	1735-3688 ; 0253-0716
ISSN (online)	1735-3688
ISSN	0253-0716
DOI	10.30476/ijms.2021.90586.2166
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Article ; Online: Evaluation of stability and maturity indices during composting process from a mixture of poultry waste and sawdust by windrow method

Asghar Yavari / Mehdi Moradi Nazar / Seyedeh Maryam Sharafi / Amir Hossein Nafez / Meghdad Pirsaheb

سلامت و محیط, Vol 15, Iss 1, Pp 1-

2022 Volume 16

Abstract: Background and Objective: It is important to determine the quality of the compost to use compost properly. The aim of this study was to determine the effect of mixing ratio of bulking agent on stability and maturity indices in poultry waste compost. ... ...

Abstract	Background and Objective: It is important to determine the quality of the compost to use compost properly. The aim of this study was to determine the effect of mixing ratio of bulking agent on stability and maturity indices in poultry waste compost. Materials and Methods: Two piles of sawdust mixture with poultry wastes and volume ratios of 1:1 (W1) and 2:1 (W2) were prepared by Windrow method and a pile containing poultry manure was used as control (W0). In order to determine the stability and maturity indices in compost, the most important physicochemical and biological parameters were studied. Results: The thermophilic phase lasted about 7 weeks for W1 and about 4 weeks for W2. The initial C/N ratios in the W0, W1 and W2 were 27.10, 31.40 and 56.24, respectively, which eventually reached less than 20. The reduction of organic matter in the three piles was 8.30%, 62.59% and 85.53%, respectively. The thermophilic phase caused a sharp decrease in the population of indicator and pathogenic microorganisms in all piles. The highest dehydrogenase activity in W1 pile was 2.95 mgTPF/gDW.h and by decreasing temperature until the last day, its value decreased to 0.29 mgTPF/gDW.h. Conclusion: The best ratio for mixing sawdust with poultry manure was 1:1 (v:v). Microbial and enzymatic activities are useful parameters for monitoring poultry composting process and determining the rate of compost stability, and the use of this compost in agriculture will improve soil quality.
Keywords	composting ; windrow method ; poultry waste ; sawdust ; stability indices ; Environmental sciences ; GE1-350
Subject code	660
Language	Persian
Publishing date	2022-04-01T00:00:00Z
Publisher	Tehran University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Anti-

Mohamadi, Fereshteh / Shakibapour, Mahshid / Sharafi, Seyedeh Maryam / Reza, Ali Andalib / Tolouei, Sepideh / Darani, Hossein Yousofi

Biomedical reports

2019 Volume 10, Issue 3, Page(s) 183–188

Abstract: Toxoplasma gondii (T. gondii) ...

Abstract	Toxoplasma gondii (T. gondii)
Language	English
Publishing date	2019-01-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2763624-0
ISSN	2049-9442 ; 2049-9434
ISSN (online)	2049-9442
ISSN	2049-9434
DOI	10.3892/br.2019.1186
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Article ; Online: Meta-Analysis on the Association of C-Reactive Protein Polymorphisms with Metabolic Syndrome.

Sharafi, Seyedeh Maryam / Mahdavi, Manijeh / Riahi, Roya / Kheirollahi, Majid / Kelishadi, Roya

Global medical genetics

2020 Volume 7, Issue 1, Page(s) 8–13

Abstract: Polymorphisms in the C-reactive protein (CRP) genes might have crucial role in the development of metabolic syndrome (MetS). In the current comprehensive meta-analyses, we aim to provide a quantitative assessment of the association between CRP single- ... ...

Abstract	Polymorphisms in the C-reactive protein (CRP) genes might have crucial role in the development of metabolic syndrome (MetS). In the current comprehensive meta-analyses, we aim to provide a quantitative assessment of the association between CRP single-nucleotide polymorphisms (SNPs) and the risk of MetS. An electronic search was performed on several databases. After data extraction, random effect model was used to calculate the pooled odds ratio (OR) and 95% confidence intervals (CIs). Four independent studies including case-control, cohort, and cross-sectional methods were analyzed. Our meta-analysis indicated that CRP polymorphisms are not significantly associated with MetS (OR = 0.92, 95% CI = 0.77-1.10) with significant heterogeneity (
Language	English
Publishing date	2020-07-09
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	3009997-3
ISSN	2699-9404 ; 2699-9404
ISSN (online)	2699-9404
ISSN	2699-9404
DOI	10.1055/s-0040-1710548
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Article: Environmental disinfection against COVID-19 in different areas of health care facilities: a review

Sharafi, Seyedeh Maryam / Ebrahimpour, Karim / Nafez, Amirhossein

Rev. environ. health

Abstract	The coronavirus disease 2019 (COVID-19) originated in bats and human-to-human transmission through respiratory droplets and contact with surfaces of infected aerosol are the main ways of transmitting this virus. Until now, there is no effective pharmaceutical treatment; conclusively it is important to evaluate the types of applied disinfectants in different areas against Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2), the virus that causes COVID-19. The aim of this review was to summarize the information about environmental disinfection for preventing of COVID-19. We performed a review of the science direct database to find articles providing information on disinfection used for SARS-CoV-2. The extracted results were given the original data on inactivation coronaviruses by disinfectants in different places of health care facilities. The final search recognized that five groups of disinfectants include: chlorine containing disinfectants, alcohol, UV irradiation, Hydrogen peroxide, and other disinfectant were used against SARS-CoV-2 in different environments. Among these groups, bleach (chlorine containing disinfectants) has the most applicability. Also, in many studies by using disinfectants with 62-71% ethanol can reduce coronavirus in contaminated areas. Furthermore, after the using of operating room for COVID-19 patients, hydrogen peroxide and UV irradiation should be used for 24 h before it can be used again. The povidone-iodine or the chlorhexidine, could be recommended when there is a risk of SARS-CoV-2 contamination especially for open wounds. According to the different studies on SARS-CoV-2 disinfection, because of the SARS-CoV-2 can remain in the air and on surfaces, as well as observing individual disinfection guidelines in different hospital areas, disinfection of surfaces is necessary to decrease SARS-CoV-2 spreading. Moreover, the most suggested disinfectants have been limited to bleach and alcohol, it's better to be considered the potential of other disinfectants in different areas.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #742558
Database	COVID19

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