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Article ; Online: Performance evaluation of DEWMA3 in phase-II for capturing changes in simple linear profiles based on run rule mechanism.

Sherwani, Rehan Ahmad Khan / Qasim, Humaira / Abbas, Shumaila / Abbas, Tahir / Aslam, Muhammad

2023 Volume 13, Issue 1, Page(s) 8609

Abstract: In Statistical Process Control, many techniques exist for monitoring the stability of a process over time. In this work, we study the relationship of the response variable with explanatory variables in the form of linear profiles for detecting changes in ...

Abstract	In Statistical Process Control, many techniques exist for monitoring the stability of a process over time. In this work, we study the relationship of the response variable with explanatory variables in the form of linear profiles for detecting changes in slope and intercept of the linear quality profiles. We used the transformation of explanatory variables approach used for make the regression estimates independent of each other to have zero average. A comparative study of three phase-II methods using DEWMA statistics in monitoring and capturing undesirable deviations in the slope, intercept, and variability is also studied by applying different proposed run rules schemes i.e., R
Language	English
Publishing date	2023-05-27
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-35779-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Bactericidal potential of different size sericin-capped silver nanoparticles synthesized by heat, light, and sonication.

Summer, Muhammad / Tahir, Hafiz Muhammad / Ali, Shaukat / Abaidullah, Rimsha / Mumtaz, Shumaila / Nawaz, Saira / Azizullah

Journal of basic microbiology

2023 Volume 63, Issue 9, Page(s) 1016–1029

Abstract: Present study was aimed to assess the bactericidal potential of sericin-capped silver nanoparticles (Se-AgNPs) synthesized by heat, light, and sonication. Se-AgNPs were characterized by size analyzer, UV spectrophotometry, energy-dispersive X-ray ... ...

Abstract	Present study was aimed to assess the bactericidal potential of sericin-capped silver nanoparticles (Se-AgNPs) synthesized by heat, light, and sonication. Se-AgNPs were characterized by size analyzer, UV spectrophotometry, energy-dispersive X-ray spectroscopy, and Fourier transform infrared spectroscopy. Average size of Se-AgNPs synthesized by heat, light and sonication was 53.60, 78.12, and 7.49 nm, respectively. All (10) bacterial strains were exposed to Se-AgNPs prepared from different methods to compare their antibacterial potentials. Largest zone of inhibition (13 ± 1.15 mm) was observed for sonication-based nanoparticles (NPs) against Klebseilla pneumoniae while the smallest zone of light assisted NPs against Serratia rubidaea (5 ± 1 mm). Bacterial strains were also exposed to different concentrations (0.2%, 0.3%, and 0.6%) of Se-AgNPs which showed largest zone (12 ± 1 mm) of inhibition for 0.4% of Se-AgNPs against Protius mirabilis and smallest zone (5 ± 1.154 mm) for 0.3% of Se-AgNPs against Escherichia coli. Furthermore, effect of different temperatures (5°C, 37°C, and 60°C) and pH (3, 7, and 12) on the efficacy and stability of Se-AgNPs was also evaluated against different bacterial strains. Sonication mediated NPs showed highest bactericidal results against K. pneumoniae (F
MeSH term(s)	Silver/pharmacology ; Silver/chemistry ; Sericins ; Metal Nanoparticles/chemistry ; Hot Temperature ; Sonication ; Microbial Sensitivity Tests ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/chemistry ; Bacteria ; Plant Extracts/chemistry ; Spectroscopy, Fourier Transform Infrared
Chemical Substances	Silver (3M4G523W1G) ; Sericins ; Anti-Bacterial Agents ; Plant Extracts
Language	English
Publishing date	2023-03-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	632513-0
ISSN	1521-4028 ; 0233-111X
ISSN (online)	1521-4028
ISSN	0233-111X
DOI	10.1002/jobm.202200632
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Article ; Online: Performance evaluation of DEWMA3 in phase-II for capturing changes in simple linear profiles based on run rule mechanism

Rehan Ahmad Khan Sherwani / Humaira Qasim / Shumaila Abbas / Tahir Abbas / Muhammad Aslam

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 15

Abstract: Abstract In Statistical Process Control, many techniques exist for monitoring the stability of a process over time. In this work, we study the relationship of the response variable with explanatory variables in the form of linear profiles for detecting ... ...

Abstract	Abstract In Statistical Process Control, many techniques exist for monitoring the stability of a process over time. In this work, we study the relationship of the response variable with explanatory variables in the form of linear profiles for detecting changes in slope and intercept of the linear quality profiles. We used the transformation of explanatory variables approach used for make the regression estimates independent of each other to have zero average. A comparative study of three phase-II methods using DEWMA statistics in monitoring and capturing undesirable deviations in the slope, intercept, and variability is also studied by applying different proposed run rules schemes i.e., R1/1, R2/3, R3/3. Monte Carlo simulations were carried out on R-Software for finding the results of proposed schemes by taking various levels of shifts for intercept, slope, and standard deviation in identifying the false alarm rate of a process. The simulation results based on the average run length criterion show that the proposed run rule schemes improve the detection ability of the control structure. Among all the proposed schemes R2/3 is found to be the best one because of its quick detection ability of false alarm rate. The proposed scheme also shows superiority in comparison to other schemes. The simulation results are further justified with a real data application.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A meta-analysis and experimental data for multidrug resistance genes in breast cancer.

Zaib, Shumaila / Tahir, Sammia / Masood, Nosheen / Hameed, Abdul / Azra, Yasmin

African health sciences

2022 Volume 22, Issue 4, Page(s) 1–9

Abstract: Background: Increasing trend of breast cancer incidence worldwide is a known fact. This curable disease may become fatal if drug resistance is developed leading to metastatic cancerous tissue.: Objective: This is a two parts study; a meta-analysis ... ...

Abstract	Background: Increasing trend of breast cancer incidence worldwide is a known fact. This curable disease may become fatal if drug resistance is developed leading to metastatic cancerous tissue. Objective: This is a two parts study; a meta-analysis exploring association of drug resistance (mdr1 and ABCG2) genes with breast cancer and mutational association with molecular subtypes of cancer. Methods: PCR-SSCP for genomic polymorphisms and RT-PCR for expression analysis were performed. Results: C3435T polymorphism of mdr1 gene was most commonly studied mutation with contradictory results. Association of ABCG2 gene mutations with untreated breast cancer was reported only by one study so far. Regarding current genomic analysis of mdr1 gene, three novel mutations were found in exon 12 and 2 mutations were found in exon 26. In ABCG2 gene, addition of C and T were found in intron 8 at the intron-exon junction. A positive correlation was observed between these mutations and tumor grade. Levels of mRNA expression revealed that they were over expressed in cancerous tissues compared with controls. Conclusion: These findings suggest that these genes are associated with breast cancer.
MeSH term(s)	Humans ; Female ; ATP Binding Cassette Transporter, Subfamily B/genetics ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP Binding Cassette Transporter, Subfamily B, Member 1/therapeutic use ; Genes, MDR ; Genotype ; Breast Neoplasms/drug therapy ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Case-Control Studies
Chemical Substances	ATP Binding Cassette Transporter, Subfamily B ; ATP Binding Cassette Transporter, Subfamily B, Member 1
Language	English
Publishing date	2022-04-18
Publishing country	Uganda
Document type	Meta-Analysis ; Journal Article
ZDB-ID	2240308-5
ISSN	1729-0503 ; 1680-6905
ISSN (online)	1729-0503
ISSN	1680-6905
DOI	10.4314/ahs.v22i4.2
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Article ; Online: Advanced treatment strategies in breast cancer: A comprehensive mechanistic review.

Mumtaz, Samaira / Ali, Shaukat / Mumtaz, Shumaila / Pervaiz, Asim / Tahir, Hafiz M / Farooq, Muhammad A / Mughal, Tafail A

Science progress

2023 Volume 106, Issue 2, Page(s) 368504231175331

Abstract: Breast cancer is a destructive lump type that affects women globally. Despite the availability of multi-directional therapeutic strategies, advanced stages of breast cancer are difficult to treat and impose major healthcare burdens. This situation ... ...

Abstract	Breast cancer is a destructive lump type that affects women globally. Despite the availability of multi-directional therapeutic strategies, advanced stages of breast cancer are difficult to treat and impose major healthcare burdens. This situation reinforces the need to identify new potential therapeutic compounds with better clinical features. In this context, different treatment methods were included such as Endocrine therapy, chemotherapy, Radiation therapy, antimicrobial peptide-dependent growth inhibitor, liposome-based drug delivery, antibiotics used as a co-medication, photothermal, immunotherapy, and nano drug delivery systems such as
MeSH term(s)	Animals ; Female ; Humans ; Sericins/metabolism ; Sericins/pharmacology ; Bombyx/metabolism ; Breast Neoplasms/therapy ; Nanoparticles/therapeutic use
Chemical Substances	Sericins
Language	English
Publishing date	2023-05-26
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	128412-5
ISSN	2047-7163 ; 0036-8504 ; 0302-1785
ISSN (online)	2047-7163
ISSN	0036-8504 ; 0302-1785
DOI	10.1177/00368504231175331
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Article ; Online: Alkanna tinctoria-based sustainable alkanin natural colorant for eco-dyeing of wool

Adeel, Shahid / Kiran, Shumaila / Alam, Mehboob / Farooq, Tahir / Amin, Nimra / Gulzar, Tahsin

Environ Sci Pollut Res. 2023 Feb., v. 30, no. 10 p.27073-27080

2023

Abstract: The awareness of sustainability and widespread utilization of green technologies in textile dye houses are revolutionizing not only textile industries but related fields. The current study is concerned with ultrasonic (US)-assisted utilization of ... ...

Abstract	The awareness of sustainability and widespread utilization of green technologies in textile dye houses are revolutionizing not only textile industries but related fields. The current study is concerned with ultrasonic (US)-assisted utilization of extracts of Alkanna tinctoria (a source of natural alkanin dye) for wool dyeing. The extracts are obtained in various media, and both extracts and wool fabrics have been US treated for 15–60 min. Dyeing is performed by applying variable parameters and utilizing herbal-based extracts as a source of bio-mordant, hence improving the fastness rating and enhancing color strength. Good color strength and fastness ratings are obtained using irradiated extract at 4 pH when the US-treated wool fabric is dyed at 65 °C for 60 min before and after chemical and bio-mordanting. For comparative studies, chemical mordants are also employed. In contrast to chemical mordants, the bio-mordants have made the dyeing process more sustainable with good to excellent fastness rating.
Keywords	Alkanna ; color ; dyeing ; dyes ; irradiation ; mordants ; pH ; ultrasonics ; wool ; woolen fabric
Language	English
Dates of publication	2023-02
Size	p. 27073-27080.
Publishing place	Springer Berlin Heidelberg
Document type	Article ; Online
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-23806-y
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Toxicological effects of dimethlybenzeneanthracene in Balb C mice and pharmacological intervention by silk sericin-conjugated silver nanoparticles.

Mumtaz, Samaira / Ali, Shaukat / Pervaiz, Asim / Awan, Uzma Azeem / Nauroze, Tooba / Kanwal, Lubna / Summer, Muhammad / Mumtaz, Shumaila / Mughal, Tafail Akbar / Tahir, Hafiz Muhammad

Science progress

2024 Volume 107, Issue 1, Page(s) 368504231221670

Abstract: Polycyclic aromatic hydrocarbons (PAHs) such as 7, 12-dimethylbenzneanthracene (DMBA), due to long-term bioaccumulation cause serious physiological processes and behavioral dysfunctions such as cancer, ageing, and hypertension. Silk sericin (SS) is ... ...

Abstract	Polycyclic aromatic hydrocarbons (PAHs) such as 7, 12-dimethylbenzneanthracene (DMBA), due to long-term bioaccumulation cause serious physiological processes and behavioral dysfunctions such as cancer, ageing, and hypertension. Silk sericin (SS) is instrumental in cancer applications due to presence of flavonoids and carotenoids which are natural pigments, present in the layer of sericin that has antioxidant and antityrosinase activity. It reduces oxidative stress and suppresses cancer cytokines while interacting with reactive oxygen species (ROS) to stand against lipid peroxidation. Recent research was focused to calculate the pharmacological intervention of sericin-conjugated silver nanoparticles (S-AgNO
MeSH term(s)	Female ; Mice ; Animals ; Sericins/therapeutic use ; Sericins/toxicity ; Silver/toxicity ; Mice, Inbred BALB C ; Metal Nanoparticles/therapeutic use ; Metal Nanoparticles/toxicity ; Alkaline Phosphatase ; Silk/chemistry ; Neoplasms ; Glutathione/metabolism ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Lactate Dehydrogenases
Chemical Substances	Sericins ; Silver (3M4G523W1G) ; Alkaline Phosphatase (EC 3.1.3.1) ; Silk ; Glutathione (GAN16C9B8O) ; Immunoglobulin A ; Immunoglobulin G ; Immunoglobulin M ; Lactate Dehydrogenases (EC 1.1.-)
Language	English
Publishing date	2024-01-17
Publishing country	England
Document type	Journal Article
ZDB-ID	128412-5
ISSN	2047-7163 ; 0036-8504 ; 0302-1785
ISSN (online)	2047-7163
ISSN	0036-8504 ; 0302-1785
DOI	10.1177/00368504231221670
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Article ; Online: A Comparative Study of

Zreen, Zohra / Hameed, Amjad / Kiran, Shumaila / Farooq, Tahir / Zaroog, Mohammed Suleiman

BioMed research international

2022 Volume 2022, Page(s) 4746223

Abstract: Keeping in mind the ascribed repute ... ...

Abstract	Keeping in mind the ascribed repute of
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/pharmacology ; Antifungal Agents ; Antioxidants/chemistry ; Antioxidants/pharmacology ; Diospyros ; Ethanol ; Flavonoids/pharmacology ; Hypoglycemic Agents ; Methanol ; Methylene Chloride ; Phenols/chemistry ; Phenols/pharmacology ; Phytochemicals/pharmacology ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Saponins ; Solvents ; Tannins/pharmacology ; Terpenes
Chemical Substances	Anti-Bacterial Agents ; Anti-Inflammatory Agents ; Antifungal Agents ; Antioxidants ; Flavonoids ; Hypoglycemic Agents ; Phenols ; Phytochemicals ; Plant Extracts ; Saponins ; Solvents ; Tannins ; Terpenes ; Ethanol (3K9958V90M) ; Methylene Chloride (588X2YUY0A) ; Methanol (Y4S76JWI15)
Language	English
Publishing date	2022-06-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2022/4746223
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Article: Infection Dynamics of

Zafar Khan, Muhammad Umar / Khalid, Shumaila / Humza, Muhammad / Yang, Shunli / Alvi, Mughees Aizaz / Munir, Tahir / Ahmad, Waqar / Iqbal, Muhammad Zahid / Tahir, Muhammad Farooq / Liu, Yongsheng / Zhang, Jie

Frontiers in veterinary science

2022 Volume 9, Page(s) 762449

Abstract: Clostridium ... ...

Abstract	Clostridium perfringens
Language	English
Publishing date	2022-07-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2834243-4
ISSN	2297-1769
ISSN	2297-1769
DOI	10.3389/fvets.2022.762449
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Article ; Online: A Comparative Study of Diospyros malabarica (Gaub) Extracts in Various Polarity-Dependent Solvents for Evaluation of Phytoconstituents and Biological Activities

Zohra Zreen / Amjad Hameed / Shumaila Kiran / Tahir Farooq / Mohammed Suleiman Zaroog

BioMed Research International, Vol

2022 Volume 2022

Abstract: Keeping in mind the ascribed repute of Diospyros malabarica (D. malabarica), this investigation was commenced to assess the effect of diverse solvents on extraction yields, phytochemical components and antioxidant capability, and in vitro biological ... ...

Abstract	Keeping in mind the ascribed repute of Diospyros malabarica (D. malabarica), this investigation was commenced to assess the effect of diverse solvents on extraction yields, phytochemical components and antioxidant capability, and in vitro biological activities of D. malabarica for pharmaceutically active constituents to combat various infections. To screen phytochemicals both qualitatively (flavonoids, terpenoid, saponins, tannins) and quantitatively like total phenolic and flavonoid contents, Diospyros malabarica parts include the following: root, leaves, bark, stem, ripe, and unripe fruit were sequentially extracted with organic solvents such as petroleum ether, dichloromethane, ethyl acetate, ethanol, methanol, and water in increasing order of polarity from less polar to more polar solvents. Furthermore, biological activities such as antibacterial, antifungal, anticancer, antidiabetic, and anti-inflammatory were explored. The results revealed that all the tested solvents displayed a vital role in the extraction yield, the content of phytochemicals, and the studied biological activities. Methanol was found as the best solvent followed by the ethanol for the extraction, representing the highest extraction yield (18.3%), rich diversity of phytochemicals, and the highest total phenolic contents (602±0.001 μg EAG/mg of extract) and total flavonoid contents (455±0.6 μg EQ/mg of extract) in bark extract. Furthermore, methanol bark extract showed high in vitro antibacterial activity (30.25 mm±0.9), antifungal activity (18.25 mm±0.2), anticancer activity (48%), antidiabetic activity (68%) and anti-inflammatory activity (62%) followed by ethanol amongst other extracts of D. malabarica. Accordingly, methanol might be as an ideal solvent to get maximum content of phytochemicals, promising antioxidants, and in vitro biological activities from bark extract amongst other extracts of D. malabarica compared to pet ether, ethyl acetate, and dichloromethane and may act as free radical rummager because phytochemical constituents ...
Keywords	Medicine ; R
Subject code	571
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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