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Article ; Online: Exploring antecedents and outcomes of burnout among emergency department staff using the job demands-resources model: A scoping review protocol.

Yang, Luhuan / Lei, Yunhong / Chu, Dongmei / Jiang, Jiawei / Li, Zifeng / Tang, Yanhua / Anita, Abd Rahman

2024 Volume 19, Issue 3, Page(s) e0300040

Abstract: Introduction: High levels of burnout are prevalent among Emergency Department staff due to chronic exposure to job stress. There is a lack of knowledge about anteceding factors and outcomes of burnout in this population.: Aims: To provide a ... ...

Abstract	Introduction: High levels of burnout are prevalent among Emergency Department staff due to chronic exposure to job stress. There is a lack of knowledge about anteceding factors and outcomes of burnout in this population. Aims: To provide a comprehensive overview of burnout and identify its workplace antecedents and outcomes among Emergency Department staff. Methods: The scoping study will follow the methodology outlined by the Joanna Briggs Institute. PubMed, Scopus, Web of Science, APA PsycInfo, and CINAHL databases will be searched using predefined strategies. Two reviewers will screen the title, abstract and full text separately based on the eligibility criteria. Data will be charted, coded, and narratively synthesized based on the job demands-resources model. Conclusion: The results will provide insights into the underlying work-related factors contributing to burnout and its implications for individuals, healthcare organizations, and patient care.
MeSH term(s)	Humans ; Burnout, Professional/epidemiology ; Occupational Stress/epidemiology ; Emergency Service, Hospital ; Review Literature as Topic
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0300040
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Assessing the current genetic structure of 21 remnant populations and predicting the impacts of climate change on the geographic distribution of Phoebe sheareri in southern China

Wang, Yang / Ma, Xiaohua / Lu, Yunfeng / Hu, Xiange / Lou, Luhuan / Tong, Zaikang / Zhang, Junhong

Science of the total environment. 2022 Nov. 10, v. 846

2022

Abstract: Phoebe sheareri is a valuable tree species known as “Golden Nanmu” and is one of the most important protected tree species in China. However, natural populations are decreasing because of climate change and anthropogenic factors. To evaluate the genetic ... ...

Abstract	Phoebe sheareri is a valuable tree species known as “Golden Nanmu” and is one of the most important protected tree species in China. However, natural populations are decreasing because of climate change and anthropogenic factors. To evaluate the genetic diversity and structure of remnant populations and the impacts of climate change on the distribution of potential suitable habitats, we conducted a field investigation and sampled 21 P. sheareri natural populations to evaluate their genetic diversity and structure using simple sequence repeat (SSR) molecular markers. Then, we predicted the distribution of suitable P. sheareri habitats across China under future scenarios (RCP 2.6 and RCP 8.5) and periods (2050 and 2070) using multivariate modeling methods—the MaxEnt model. The results showed a medium level of genetic diversity and low inbreeding in the 21 P. sheareri natural populations, and genetic differentiation among populations was significant, with 21.2 % genetic variation among populations. The remnant populations of P. sheareri were grouped into four genetic clusters based on genetic structure; five environmental variables involving four temperature variables and precipitation seasonality (Bio12) might determine the distribution of P. sheareri populations. In the future, the suitable habitats of P. sheareri are manifested as northward migration, and the highly suitable habitats are expected to increase. Our results highlight the importance of conservation units in situ, giving priority to populations with higher genetic diversity (e.g., TMS, FJS, and THY populations); sampling strategies for ex situ conservation, breeding and reforestation should consider climate change, especially Bio1 (annual mean temperature) and Bio12 (annual precipitation). Overall, this study may provide useful genetic information for strategies for the protection, management, and utilization of P. sheareri.
Keywords	Phoebe ; atmospheric precipitation ; climate change ; ex situ conservation ; genetic structure ; genetic variation ; geographical distribution ; microsatellite repeats ; models ; reforestation ; temperature ; trees ; China
Language	English
Dates of publication	2022-1110
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.157391
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Assessing the current genetic structure of 21 remnant populations and predicting the impacts of climate change on the geographic distribution of Phoebe sheareri in southern China.

Wang, Yang / Ma, Xiaohua / Lu, Yunfeng / Hu, Xiange / Lou, Luhuan / Tong, Zaikang / Zhang, Junhong

The Science of the total environment

2022 Volume 846, Page(s) 157391

Abstract: Phoebe sheareri is a valuable tree species known as "Golden Nanmu" and is one of the most important protected tree species in China. However, natural populations are decreasing because of climate change and anthropogenic factors. To evaluate the genetic ... ...

Abstract	Phoebe sheareri is a valuable tree species known as "Golden Nanmu" and is one of the most important protected tree species in China. However, natural populations are decreasing because of climate change and anthropogenic factors. To evaluate the genetic diversity and structure of remnant populations and the impacts of climate change on the distribution of potential suitable habitats, we conducted a field investigation and sampled 21 P. sheareri natural populations to evaluate their genetic diversity and structure using simple sequence repeat (SSR) molecular markers. Then, we predicted the distribution of suitable P. sheareri habitats across China under future scenarios (RCP 2.6 and RCP 8.5) and periods (2050 and 2070) using multivariate modeling methods-the MaxEnt model. The results showed a medium level of genetic diversity and low inbreeding in the 21 P. sheareri natural populations, and genetic differentiation among populations was significant, with 21.2 % genetic variation among populations. The remnant populations of P. sheareri were grouped into four genetic clusters based on genetic structure; five environmental variables involving four temperature variables and precipitation seasonality (Bio12) might determine the distribution of P. sheareri populations. In the future, the suitable habitats of P. sheareri are manifested as northward migration, and the highly suitable habitats are expected to increase. Our results highlight the importance of conservation units in situ, giving priority to populations with higher genetic diversity (e.g., TMS, FJS, and THY populations); sampling strategies for ex situ conservation, breeding and reforestation should consider climate change, especially Bio1 (annual mean temperature) and Bio12 (annual precipitation). Overall, this study may provide useful genetic information for strategies for the protection, management, and utilization of P. sheareri.
MeSH term(s)	China ; Climate Change ; Ecosystem ; Lauraceae ; Microsatellite Repeats ; Plant Breeding
Language	English
Publishing date	2022-07-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2022.157391
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Enantioseparation and determination of oxypeucedanin and its application to a stereoselective analysis in Angelica Dahuricae Radix and pharmacokinetic study of rats

Tang, LuHuan / Wang, YuMing / Yang, JiaXuan / Shu, LeXin / Ding, Haoran / Yao, Yaqi / Li, Yubo

Journal of chromatography. 2022 Sept. 01, v. 1207

2022

Abstract: In this study, a new enantioseparation method was established for the quantitative analysis of the oxypeucedanin enantiomers by using cellulose tris(3,5-dichlorophenyl carbamate) stationary phase column Chiralpak IC. For this method, enantiomeric ... ...

Abstract	In this study, a new enantioseparation method was established for the quantitative analysis of the oxypeucedanin enantiomers by using cellulose tris(3,5-dichlorophenyl carbamate) stationary phase column Chiralpak IC. For this method, enantiomeric separation of oxypeucedanin was achieved with the mobile phase consisting of acetonitrile-water (60:40, v/v) at a flow rate of 0.5 mL/min by changing the type and proportion of mobile phase. And the quantitative determination of racemic oxypeucedanin in Angelica Dahuricae Radix (in vitro) and rat plasma (in vivo) were performed on above-mentioned condition by High PerformanceLiquid Chromatography combined with diode arrangement detector (HPLC-DAD) and mass spectrometry (HPLC-MS/MS). The precision, repeatability, stability, recovery were within the acceptance criteria. And the method was validated in the concentration range of 1-400 μg/mL for the two enantiomers in vitro and 0.2–600 ng/mL in vivo. After validation, the established method was successfully applied to the stereoselective analysis of racemic oxypeucedanin in Angelica dahurica from different regions and the stereoselective pharmacokinetic investigation in rat. Results showed that the (+)-oxypeucedanin was at a relative high level in Angelica dahuricae Radix and (−)-oxypeucedanin performed a higher plasma concentration, which demonstrated the difference of oxypeucedanin enantiomers both in vitro and in vivo.
Keywords	Angelica dahurica ; cellulose ; diodes ; enantiomers ; pharmacokinetics ; quantitative analysis ; rats ; stereoselectivity
Language	English
Dates of publication	2022-0901
Publishing place	Elsevier B.V.
Document type	Article
ISSN	1570-0232
DOI	10.1016/j.jchromb.2022.123355
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Enantioseparation and determination of oxypeucedanin and its application to a stereoselective analysis in Angelica Dahuricae Radix and pharmacokinetic study of rats.

Tang, LuHuan / Wang, YuMing / Yang, JiaXuan / Shu, LeXin / Ding, Haoran / Yao, Yaqi / Li, Yubo

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

2022 Volume 1207, Page(s) 123355

Abstract	In this study, a new enantioseparation method was established for the quantitative analysis of the oxypeucedanin enantiomers by using cellulose tris(3,5-dichlorophenyl carbamate) stationary phase column Chiralpak IC. For this method, enantiomeric separation of oxypeucedanin was achieved with the mobile phase consisting of acetonitrile-water (60:40, v/v) at a flow rate of 0.5 mL/min by changing the type and proportion of mobile phase. And the quantitative determination of racemic oxypeucedanin in Angelica Dahuricae Radix (in vitro) and rat plasma (in vivo) were performed on above-mentioned condition by High PerformanceLiquid Chromatography combined with diode arrangement detector (HPLC-DAD) and mass spectrometry (HPLC-MS/MS). The precision, repeatability, stability, recovery were within the acceptance criteria. And the method was validated in the concentration range of 1-400 μg/mL for the two enantiomers in vitro and 0.2-600 ng/mL in vivo. After validation, the established method was successfully applied to the stereoselective analysis of racemic oxypeucedanin in Angelica dahurica from different regions and the stereoselective pharmacokinetic investigation in rat. Results showed that the (+)-oxypeucedanin was at a relative high level in Angelica dahuricae Radix and (-)-oxypeucedanin performed a higher plasma concentration, which demonstrated the difference of oxypeucedanin enantiomers both in vitro and in vivo.
MeSH term(s)	Angelica/chemistry ; Animals ; Chromatography, High Pressure Liquid/methods ; Furocoumarins ; Rats ; Tandem Mass Spectrometry/methods
Chemical Substances	Furocoumarins ; oxypeucadanin (S1Y67F37PI)
Language	English
Publishing date	2022-07-05
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1180823-8
ISSN	1873-376X ; 0378-4347 ; 1570-0232 ; 1387-2273
ISSN (online)	1873-376X
ISSN	0378-4347 ; 1570-0232 ; 1387-2273
DOI	10.1016/j.jchromb.2022.123355
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Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Degradation of river ecological quality in Tibet plateau with overgrazing

Lihua Niu / Yuntong Guo / Yi Li / Chao Wang / Qing Hu / Luhuan Fan / Linqiong Wang / Nan Yang

Ecological Indicators, Vol 120, Iss , Pp 106948- (2021)

A quantitative assessment using biotic integrity index improved by random forest

2021

Abstract: The river ecosystem in fragile regions is especially vulnerable to environmental or anthropogenic stressors. The ecological quality and stability of rivers in fragile regions urgently need to be evaluated before the reasonable protection and restoration. ...

Abstract	The river ecosystem in fragile regions is especially vulnerable to environmental or anthropogenic stressors. The ecological quality and stability of rivers in fragile regions urgently need to be evaluated before the reasonable protection and restoration. In this study, a random-forest-modified bacterial index of biological integrity (RF-BaIBI) was developed for ecological assessment of fragile rivers in the sources of Yangtze River and Yellow River (abbreviated as SYY) in Tibet Plateau, China. Three key bacterial metrics including Enterobacteriale, Fluviicola, and Oxalobacteraceae, were selected for the development of RF-BaIBI using range, responsiveness, redundancy tests, as well as random forest. The weight coefficients of metrics were calculated based on their relative importance to RF-BaIBI: Enterobacteriale (0.41), Fluviicola (0.34) and Oxalobacteraceae (0.25). The feasibility of RF-BaIBI was confirmed by its significant correlation with comprehensive environmental index (R2 = 0.71). Among 45 river sections, those with high or good status accounted for 26%, with moderate 51% and poor 13%. Redundancy and path analysis revealed that livestock grazing density was the most dominant factor influencing ecological conditions of the SYY. Under the pressure of grazing, rivers in the source of Yangtze River displayed higher stability than that of Yellow River via the resistance and co-occurrence network analyses. Compared to that of Yellow River, bacterial communities from the source of Yangtze River exhibited stronger competitive interaction which is very beneficial to the stability of the ecosystem. This study highlighted the great effect of overgrazing on the degradation of river ecological health status in Tibet Plateau based on the quantitative assessment of biotic integrity index, which provides a theoretical basis for the management of grazing in fragile plateau regions.
Keywords	Fragile region ; Yangtze River ; Yellow River ; Bacterial metrics ; Stability ; Resistance ; Ecology ; QH540-549.5
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Degradation of river ecological quality in Tibet plateau with overgrazing: A quantitative assessment using biotic integrity index improved by random forest

Niu, Lihua / Guo, Yuntong / Li, Yi / Wang, Chao / Hu, Qing / Fan, Luhuan / Wang, Linqiong / Yang, Nan

Ecological indicators. 2021 Jan., v. 120

2021

Abstract	The river ecosystem in fragile regions is especially vulnerable to environmental or anthropogenic stressors. The ecological quality and stability of rivers in fragile regions urgently need to be evaluated before the reasonable protection and restoration. In this study, a random-forest-modified bacterial index of biological integrity (RF-BaIBI) was developed for ecological assessment of fragile rivers in the sources of Yangtze River and Yellow River (abbreviated as SYY) in Tibet Plateau, China. Three key bacterial metrics including Enterobacteriale, Fluviicola, and Oxalobacteraceae, were selected for the development of RF-BaIBI using range, responsiveness, redundancy tests, as well as random forest. The weight coefficients of metrics were calculated based on their relative importance to RF-BaIBI: Enterobacteriale (0.41), Fluviicola (0.34) and Oxalobacteraceae (0.25). The feasibility of RF-BaIBI was confirmed by its significant correlation with comprehensive environmental index (R² = 0.71). Among 45 river sections, those with high or good status accounted for 26%, with moderate 51% and poor 13%. Redundancy and path analysis revealed that livestock grazing density was the most dominant factor influencing ecological conditions of the SYY. Under the pressure of grazing, rivers in the source of Yangtze River displayed higher stability than that of Yellow River via the resistance and co-occurrence network analyses. Compared to that of Yellow River, bacterial communities from the source of Yangtze River exhibited stronger competitive interaction which is very beneficial to the stability of the ecosystem. This study highlighted the great effect of overgrazing on the degradation of river ecological health status in Tibet Plateau based on the quantitative assessment of biotic integrity index, which provides a theoretical basis for the management of grazing in fragile plateau regions.
Keywords	Oxalobacteraceae ; anthropogenic stressors ; ecosystems ; environmental health ; health status ; livestock ; path analysis ; rivers ; China ; Yangtze River ; Yellow River
Language	English
Dates of publication	2021-01
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2036774-0
ISSN	1872-7034 ; 1470-160X
ISSN (online)	1872-7034
ISSN	1470-160X
DOI	10.1016/j.ecolind.2020.106948
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Concurrence of primary pulmonary malignant melanoma with invasive pulmonary adenocarcinoma: a case report.

Yang, Luhuan / Lei, Yunhong / Zhang, Rong / Liu, Yufei / Dai, Wenli / Tian, Fei / Liu, Jinglan

Journal of cardiothoracic surgery

2020 Volume 15, Issue 1, Page(s) 51

Abstract: Background: Primary pulmonary malignant melanoma (PPMM) is an extreme rarity in clinic practice, accounting for only 0.01% of all primary pulmonary tumors. And its diagnosis should meet clinical and pathological diagnosis criteria in addition to ... ...

Abstract	Background: Primary pulmonary malignant melanoma (PPMM) is an extreme rarity in clinic practice, accounting for only 0.01% of all primary pulmonary tumors. And its diagnosis should meet clinical and pathological diagnosis criteria in addition to excluding the possibility of metastatic melanoma. The mainstay of treatment is surgery. The concurrence of primary pulmonary malignant melanoma and invasive pulmonary adenocarcinoma has not been reported before. Case presentation: Herein we report the case of a 39-year-old woman who was asymptomatic and accidently found to have the concurrence of PPMM with invasive pulmonary adenocarcinoma. Before considering the diagnosis of primary pulmonary malignant melanoma, a systemic positron emission tomography-computed tomography (PET-CT) was done to excluding primary tumor metastasis from other sites. The pathological biopsy proved that two lesions in the right middle lobe were invasive pulmonary adenocarcinomas and the mass in the right lower lobe was malignant melanoma. She underwent right middle and lower lobectomy of the lung with mediastinal and hilar lymph dissection. She refused adjuvant chemotherapy, genetic molecular testing or immunotherapy. Fifteen months later she had brain metastasis. Then she received brain radiotherapy and underwent follow-up at the outpatient clinic regularly. Conclusions: We experienced a case of concurrent PPMM and invasive pulmonary adenocarcinoma. The patient reported here is the first case of primary pulmonary malignant melanoma combined with invasive pulmonary adenocarcinoma. This patient remained disease-free 15 months after lung surgery.
MeSH term(s)	Adenocarcinoma of Lung ; Adult ; Biopsy ; Brain Neoplasms/diagnostic imaging ; Brain Neoplasms/radiotherapy ; Brain Neoplasms/secondary ; Female ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Lung/surgery ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/pathology ; Lung Neoplasms/surgery ; Magnetic Resonance Imaging ; Melanoma/diagnostic imaging ; Melanoma/pathology ; Melanoma/surgery ; Neoplasms, Multiple Primary/diagnostic imaging ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/surgery ; Positron Emission Tomography Computed Tomography
Language	English
Publishing date	2020-03-26
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1749-8090
ISSN (online)	1749-8090
DOI	10.1186/s13019-020-01091-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Purification, characterization and action mechanism of plantaricin JY22, a novel bacteriocin against

Lv, Xinran / Miao, Luhuan / Ma, Huanhuan / Bai, Fengling / Lin, Yang / Sun, Mengtong / Li, Jianrong

Food science and biotechnology

2017 Volume 27, Issue 3, Page(s) 695–703

Abstract: A novel bacteriocin-producing strain, ...

Abstract	A novel bacteriocin-producing strain,
Language	English
Publishing date	2017-12-12
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2000008-X
ISSN	2092-6456 ; 1226-7708
ISSN (online)	2092-6456
ISSN	1226-7708
DOI	10.1007/s10068-017-0280-2
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Article: MRI advances in the imaging diagnosis of tuberculous meningitis: opportunities and innovations.

Frontiers in microbiology

2023 Volume 14, Page(s) 1308149

Abstract: Tuberculous meningitis (TBM) is not only one of the most fatal forms of tuberculosis, but also a major public health concern worldwide, presenting grave clinical challenges due to its nonspecific symptoms and the urgent need for timely intervention. The ... ...

Abstract	Tuberculous meningitis (TBM) is not only one of the most fatal forms of tuberculosis, but also a major public health concern worldwide, presenting grave clinical challenges due to its nonspecific symptoms and the urgent need for timely intervention. The severity and the rapid progression of TBM underscore the necessity of early and accurate diagnosis to prevent irreversible neurological deficits and reduce mortality rates. Traditional diagnostic methods, reliant primarily on clinical findings and cerebrospinal fluid analysis, often falter in delivering timely and conclusive results. Moreover, such methods struggle to distinguish TBM from other forms of neuroinfections, making it critical to seek advanced diagnostic solutions. Against this backdrop, magnetic resonance imaging (MRI) has emerged as an indispensable modality in diagnostics, owing to its unique advantages. This review provides an overview of the advancements in MRI technology, specifically emphasizing its crucial applications in the early detection and identification of complex pathological changes in TBM. The integration of artificial intelligence (AI) has further enhanced the transformative impact of MRI on TBM diagnostic imaging. When these cutting-edge technologies synergize with deep learning algorithms, they substantially improve diagnostic precision and efficiency. Currently, the field of TBM imaging diagnosis is undergoing a phase of technological amalgamation. The melding of MRI and AI technologies unquestionably signals new opportunities in this specialized area.
Language	English
Publishing date	2023-12-11
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1308149
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