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  1. Article ; Online: [No title information]

    Schmid-Grendelmeier, Peter

    Drug research

    2020  Volume 70, Issue S 01, Page(s) S10–S11

    Title translation Nahrungsmittelallergien – Vorkommen und Behandlungsstrategien.
    Language German
    Publishing date 2020-11-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-1119-2676
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to 'A case of anaphylactic shock induced by mealworm antigen in the bite of a Japanese flying squirrel' by Seshimo et al.

    Guillet, C / Schmid-Grendelmeier, P

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2021  Volume 35, Issue 9, Page(s) e617–e618

    MeSH term(s) Anaphylaxis/chemically induced ; Animals ; Humans ; Sciuridae ; Tenebrio
    Language English
    Publishing date 2021-07-21
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.17411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Decreased skin colonization with

    Storz, Lukas / Schmid, Bettina / Bosshard, Philipp Peter / Schmid-Grendelmeier, Peter / Brüggen, Marie-Charlotte / Lang, Claudia

    Frontiers in medicine

    2024  Volume 11, Page(s) 1353784

    Abstract: Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease in which patients are sensitized towards a plethora of allergens. The hosts fungal microbiota, the mycobiota, that is believed to be altered in patients suffering from ... ...

    Abstract Background: Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease in which patients are sensitized towards a plethora of allergens. The hosts fungal microbiota, the mycobiota, that is believed to be altered in patients suffering from AD acts as such an allergen. The correlation context of specific sensitization, changes in mycobiota and its impact on disease severity however remains poorly understood.
    Objectives: We aim to enhance the understanding of the specific sensitization towards the mycobiota in AD patients in relation to their fungal skin colonization.
    Methods: Sensitization pattern towards the
    Results: Sensitization in general and towards
    Conclusion: We conclude that AD in general and severe AD in particular is associated with increased sensitization towards the hosts own mycobiota. There is positive correlation in
    Language English
    Publishing date 2024-02-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1353784
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Long-term disease control in atopic dermatitis using biologics.

    Thyssen, Jacob P / Schmid-Grendelmeier, Peter

    Lancet (London, England)

    2022  Volume 401, Issue 10372, Page(s) 172–173

    MeSH term(s) Humans ; Dermatitis, Atopic/drug therapy ; Dermatitis, Atopic/prevention & control ; Biological Products/therapeutic use ; Immunosuppressive Agents
    Chemical Substances Biological Products ; Immunosuppressive Agents
    Language English
    Publishing date 2022-12-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)02347-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: CME-Fortbildung. Atopische Dermatitis Die Rolle des Schlüsselzytokins IL-13 / CME-Fortbildungsfragen

    Schmid-Grendelmeier, Peter

    Dermatologie-Praxis

    2021  Volume 31, Issue 4, Page(s) 10 / 9

    Language German
    Document type Article
    ZDB-ID 2231659-0
    ISSN 1661-6200
    Database Current Contents Medicine

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  6. Article: Nahrungsmittelallergien – Vorkommen und Behandlungsstrategien

    Schmid-Grendelmeier, Peter

    Drug Research

    2020  Volume 70, Issue S 01, Page(s) S10–S11

    Language German
    Publishing date 2020-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/a-1119-2676
    Database Thieme publisher's database

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  7. Article ; Online: Comorbidities of atopic dermatitis-what does the evidence say?

    Thyssen, Jacob P / Halling, Anne-Sofie / Schmid-Grendelmeier, Peter / Guttman-Yassky, Emma / Silverberg, Jonathan I

    The Journal of allergy and clinical immunology

    2023  Volume 151, Issue 5, Page(s) 1155–1162

    Abstract: Atopic dermatitis (AD) is a common disease that is associated with atopic and nonatopic comorbidities. There has been a growing interest in this area of AD, because presence or risk of comorbidities can in many ways impact the management of patients with ...

    Abstract Atopic dermatitis (AD) is a common disease that is associated with atopic and nonatopic comorbidities. There has been a growing interest in this area of AD, because presence or risk of comorbidities can in many ways impact the management of patients with AD. Thus, some treatments for AD may improve its comorbidities as well, whereas others may increase their risk. In this review article, we discuss various comorbidities of AD mostly on the basis of the results of recent multiple systematic reviews and meta-analyses to update readers about this rapidly developing area of dermatology. We emphasize the important information provided by studies presenting both relative risk and absolute risk, and show that AD is associated with, among others, atopic comorbidities such as asthma, rhinitis, and food allergy, nonatopic comorbidities such as ocular, psychiatric, infectious, endocrine, autoimmune, and cardiovascular diseases, and certain cancers. Clinicians need to be aware of these and be cognizant about positive and negative effects of existing and new treatments for AD.
    MeSH term(s) Humans ; Dermatitis, Atopic/epidemiology ; Dermatitis, Atopic/complications ; Comorbidity ; Asthma/epidemiology ; Food Hypersensitivity/epidemiology ; Food Hypersensitivity/complications ; Rhinitis/complications
    Language English
    Publishing date 2023-01-06
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2022.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Potential Cost Savings by Switching from Subcutaneous to Intralymphatic Insect Venom Immunotherapy.

    Chabot, Alexandra / Lang, Claudia / Kündig, Thomas M / Schmid-Grendelmeier, Peter / Johansen, Pål

    International archives of allergy and immunology

    2023  Volume 184, Issue 10, Page(s) 985–993

    Abstract: Introduction: IgE-mediated bee venom allergy can be treated with allergen-specific immunotherapy (AIT). Subcutaneous immunotherapy (SCIT) is time and cost intensive due to the repeated consultations, but the costs are justified by the high risk of ... ...

    Abstract Introduction: IgE-mediated bee venom allergy can be treated with allergen-specific immunotherapy (AIT). Subcutaneous immunotherapy (SCIT) is time and cost intensive due to the repeated consultations, but the costs are justified by the high risk of potentially life-threatening allergic reactions, including anaphylaxis. However, intralymphatic immunotherapy (ILIT) offers potential to reduce treatment costs due to a significant reduction in injections and a shorter duration of therapy. Therefore, we calculated the cost savings that arise when switching from SCIT to ILIT.
    Methods: Treatment protocols for ILIT were based on previous ILIT studies. Treatment protocols for SCIT were based on routine treatment at the University Hospital Zurich (USZ). The treatment costs were calculated based on the internal hospital information system (KISIM).
    Results: The calculations revealed a potential two-fold reduction in treatment costs if ILIT is used instead of SCIT in patients with bee venom allergy. The costs could be reduced from EUR 11,612.59 with SCIT to EUR 5,942.15 with ILIT over 5 years.
    Conclusions: This study shows that bee venom ILIT has a cost-benefit potential for health insurances and patients, which should encourage further ILIT studies and which should be taken into account when considering future implementation of ILIT in the standard care of venom allergy.
    Language English
    Publishing date 2023-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1108932-5
    ISSN 1423-0097 ; 1018-2438
    ISSN (online) 1423-0097
    ISSN 1018-2438
    DOI 10.1159/000531332
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  9. Article: Honey bee venom re-challenge during specific immunotherapy: prolonged cardio-pulmonary resuscitation allowed survival in a case of near fatal anaphylaxis.

    Micaletto, Sara / Ruetzler, Kurt / Bruesch, Martin / Schmid-Grendelmeier, Peter

    Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology

    2022  Volume 18, Issue 1, Page(s) 44

    Abstract: Background: Specific immunotherapy for patients with honey bee hypersensitivity is commonly applied. Re-challenge with venom is performed to prove protection in individual cases.: Case presenation: We report a case of near fatal anaphylaxis with ... ...

    Abstract Background: Specific immunotherapy for patients with honey bee hypersensitivity is commonly applied. Re-challenge with venom is performed to prove protection in individual cases.
    Case presenation: We report a case of near fatal anaphylaxis with asystole for 24 min in a 35-years-old patient with mastocytosis after honey bee sting challenge, despite 5-years of specific immunotherapy. Successful cardio-pulmonary resuscitation was applied for 32 min.
    Conclusion: This intervention demonstrates, that in anaphylaxis with cardio-vascular arrest, prolonged cardio-pulmonary resuscitation for up to 40 min may be appropriate to overcome the half-life of massively released histamine. Failure of specific immunotherapy was possibly due to sensitization to the allergen Api m10, potentially underrepresented in commercial honey bee venom extracts. Molecular analyses may provide additional clues to the potentially unsuccessful outcome of venom specific immunotherapy, especially in high-risk patients such as mastocytosis.
    Language English
    Publishing date 2022-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2434973-2
    ISSN 1710-1492 ; 1710-1484
    ISSN (online) 1710-1492
    ISSN 1710-1484
    DOI 10.1186/s13223-022-00687-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Medikamentenunverträglichkeit bei Histaminintoleranz und Mastozytose: «facts and fictions».

    Schmid-Grendelmeier, Peter / Schnyder, Benno

    Therapeutische Umschau. Revue therapeutique

    2019  Volume 75, Issue 1, Page(s) 38–42

    Abstract: Drug hypersensitivity in patients with presumed histamine intolerance and mast cell activation ... ...

    Title translation Drug hypersensitivity in patients with presumed histamine intolerance and mast cell activation disease.
    Abstract Drug hypersensitivity in patients with presumed histamine intolerance and mast cell activation disease
    MeSH term(s) Catechol O-Methyltransferase ; Drug Hypersensitivity ; Histamine/immunology ; Humans ; Hypersensitivity ; Mastocytosis/immunology ; Prospective Studies
    Chemical Substances Histamine (820484N8I3) ; Catechol O-Methyltransferase (EC 2.1.1.6)
    Language German
    Publishing date 2019-07-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 82044-1
    ISSN 1664-2864 ; 0040-5930
    ISSN (online) 1664-2864
    ISSN 0040-5930
    DOI 10.1024/0040-5930/a001058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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