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  1. Article ; Online: Hail netting excludes key insect pests and protects from fruit damage in a commercial Minnesota apple orchard.

    Nelson, Sally G A / Klodd, Annie E / Hutchison, William D

    Journal of economic entomology

    2023  Volume 116, Issue 6, Page(s) 2104–2115

    Abstract: Exclusion netting in some European and North American apple (Malus domestica Borkhausen, Rosaceae, Rosales) orchards has been documented to be an effective method of control for multiple insect pest species. By minimizing reliance on insecticides, these ... ...

    Abstract Exclusion netting in some European and North American apple (Malus domestica Borkhausen, Rosaceae, Rosales) orchards has been documented to be an effective method of control for multiple insect pest species. By minimizing reliance on insecticides, these orchards have reduced costs, risks to the environment and non-target species, and reduced the risk of insecticide resistance. This study examined the use of commercially available hail netting (DrapeNet®; Prosser, WA) as a pest exclusion strategy under conditions in Minnesota, USA. In 2021 and 2022, we assessed the efficacy of hail netting as a tool for pest suppression in orchards by monitoring pest species in netted and open plots crossed with and without insecticide applications. Our findings show that both of the major pest species in Minnesota, the codling moth (Cydia pomonella L.; Lepidoptera: Tortricidae) and the apple maggot (Rhagoletis pomonella Walsh; Diptera: Tephritidae), were significantly reduced inside the netting compared to open plots by 94% and 96%, respectively. For a secondary pest, the red-banded leafroller (Argyrotaenia velutinana Walker; Lepidoptera: Tortricidae), moth populations were reduced by 56%. We also found that insecticide application alone did not significantly reduce pest pressure in these species. Additionally, we investigated the subsequent effects of hail netting on fruit quality and yield. The use of hail netting and insecticide application resulted in significantly higher proportions of high-quality fruit at harvest. However, netting did not significantly influence yield. These findings suggest that hail netting can be used to control Midwest apple insect pests with limited insecticide applications while maintaining high fruit quality.
    MeSH term(s) Animals ; Insecticides/pharmacology ; Fruit ; Minnesota ; Moths ; Malus ; Tephritidae ; Insect Control/methods
    Chemical Substances Insecticides
    Language English
    Publishing date 2023-10-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3031-4
    ISSN 1938-291X ; 0022-0493
    ISSN (online) 1938-291X
    ISSN 0022-0493
    DOI 10.1093/jee/toad197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Disparities in Cancer Stage Outcomes by Catchment Areas for a Comprehensive Cancer Center.

    Desjardins, Michael R / Kanarek, Norma F / Nelson, William G / Bachman, Jamie / Curriero, Frank C

    JAMA network open

    2024  Volume 7, Issue 5, Page(s) e249474

    Abstract: Importance: The National Cancer Institute comprehensive cancer centers (CCCs) lack spatial and temporal evaluation of their self-designated catchment areas.: Objective: To identify disparities in cancer stage at diagnosis within and outside a CCC's ... ...

    Abstract Importance: The National Cancer Institute comprehensive cancer centers (CCCs) lack spatial and temporal evaluation of their self-designated catchment areas.
    Objective: To identify disparities in cancer stage at diagnosis within and outside a CCC's catchment area across a 10-year period using spatial and statistical analyses.
    Design, setting, and participants: This cross-sectional, population-based study conducted between 2010 and 2019 utilized cancer registry data for the Johns Hopkins Sidney Kimmel CCC (SKCCC). Eligible participants included patients with cancer in the contiguous US who received treatment for cancer, a diagnosis of cancer, or both at SKCCC. Patients were geocoded to zip code tabulation areas (ZCTAs). Individual-level variables included sociodemographic characteristics, smoking and alcohol use, treatment type, cancer site, and insurance type. Data analysis was performed between March and July 2023.
    Exposures: Distance between SKCCC and ZCTAs were computed to generate a catchment area of the closest 75% of patients and outer zones in 5% increments for comparison.
    Main outcomes and measures: The primary outcome was cancer stage at diagnosis, defined as early-stage, late-stage, or unknown stage. Multinomial logistic regression was used to determine associations of catchment area with stage at diagnosis.
    Results: This study had a total of 94 007 participants (46 009 male [48.94%] and 47 998 female [51.06%]; 30 195 aged 22-45 years [32.12%]; 4209 Asian [4.48%]; 2408 Hispanic [2.56%]; 16 004 non-Hispanic Black [17.02%]; 69 052 non-Hispanic White [73.45%]; and 2334 with other or unknown race or ethnicity [2.48%]), including 47 245 patients (50.26%) who received a diagnosis of early-stage cancer, 19 491 (20.73%) who received a diagnosis of late-stage cancer , and 27 271 (29.01%) with unknown stage. Living outside the main catchment area was associated with higher odds of late-stage cancers for those who received only a diagnosis (odds ratio [OR], 1.50; 95% CI, 1.10-2.05) or only treatment (OR, 1.44; 95% CI, 1.28-1.61) at SKCCC. Non-Hispanic Black patients (OR, 1.16; 95% CI, 1.10-1.23) and those with Medicaid (OR, 1.65; 95% CI, 1.46-1.86) and no insurance at time of treatment (OR, 2.12; 95% CI, 1.79-2.51) also had higher odds of receiving a late-stage cancer diagnosis.
    Conclusions and relevance: In this cross-sectional study of CCC data from 2010 to 2019, patients residing outside the main catchment area, non-Hispanic Black patients, and patients with Medicaid or no insurance had higher odds of late-stage diagnoses. These findings suggest that disadvantaged populations and those living outside of the main catchment area of a CCC may face barriers to screening and treatment. Care-sharing agreements among CCCs could address these issues.
    MeSH term(s) Humans ; Female ; Male ; Middle Aged ; Cross-Sectional Studies ; Neoplasms/epidemiology ; Cancer Care Facilities/statistics & numerical data ; Catchment Area, Health/statistics & numerical data ; Adult ; Neoplasm Staging ; Aged ; Healthcare Disparities/statistics & numerical data ; United States ; Registries
    Language English
    Publishing date 2024-05-01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ISSN 2574-3805
    ISSN (online) 2574-3805
    DOI 10.1001/jamanetworkopen.2024.9474
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Hail netting: an economically competitive IPM alternative to insecticides for Midwest apple production.

    DiGiacomo, Gigi / Nelson, Sally G A / Jacobson, John / Klodd, Annie / Hutchison, William D

    Frontiers in insect science

    2023  Volume 3, Page(s) 1266426

    Abstract: Apple orchards are highly managed agricultural ecosystems where growers typically rely on insecticides to minimize the risk of pest-related fruit losses. Apple growers practicing integrated pest management require cost-effective alternatives to ... ...

    Abstract Apple orchards are highly managed agricultural ecosystems where growers typically rely on insecticides to minimize the risk of pest-related fruit losses. Apple growers practicing integrated pest management require cost-effective alternatives to conventional insecticides for control of major pests such as codling moth (
    Language English
    Publishing date 2023-10-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 3123819-1
    ISSN 2673-8600 ; 2673-8600
    ISSN (online) 2673-8600
    ISSN 2673-8600
    DOI 10.3389/finsc.2023.1266426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Commentary on Huggins and Hodges: "Studies on Prostatic Cancer".

    Nelson, William G

    Cancer research

    2016  Volume 76, Issue 2, Page(s) 186–187

    MeSH term(s) Humans ; Male ; Prostatic Neoplasms
    Language English
    Publishing date 2016-01-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1432-1
    ISSN 1538-7445 ; 0008-5472
    ISSN (online) 1538-7445
    ISSN 0008-5472
    DOI 10.1158/0008-5472.CAN-15-3172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Time to be cool: open liquid-nitrogen cryosurgery for low-risk superficial basal cell carcinomas.

    Hunt, William Thomas Nicholas / Nelson, Toby G

    Clinical and experimental dermatology

    2022  Volume 47, Issue 10, Page(s) 1898–1899

    MeSH term(s) Carcinoma, Basal Cell/pathology ; Carcinoma, Basal Cell/surgery ; Cold Temperature ; Cryosurgery ; Humans ; Nitrogen/therapeutic use ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery
    Chemical Substances Nitrogen (N762921K75)
    Language English
    Publishing date 2022-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1111/ced.15372
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Old dog, new tricks: split-thickness skin graft harvesting from the postauricular scalp using a Silver manual dermatome.

    Hunt, William Thomas Nicholas / Nelson, Toby G

    Clinical and experimental dermatology

    2022  Volume 47, Issue 12, Page(s) 2346–2347

    MeSH term(s) Skin Transplantation ; Scalp/surgery ; Silver ; Wound Healing ; Tissue and Organ Harvesting
    Chemical Substances Silver (3M4G523W1G)
    Language English
    Publishing date 2022-09-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1111/ced.15376
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Long-Term Complications in Youth-Onset Type 2 Diabetes.

    Nelson, Robert G / Hanson, Robert L / Knowler, William C

    The New England journal of medicine

    2021  Volume 385, Issue 21, Page(s) 2015

    MeSH term(s) Adolescent ; Age of Onset ; Diabetes Mellitus, Type 1 ; Diabetes Mellitus, Type 2/complications ; Humans
    Language English
    Publishing date 2021-11-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2114053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A multinational survey characterizing the use of surgical magnifying loupes in dermatological surgery.

    Hunt, William T N / Ashraf, Iqra / Nelson, Toby G

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

    2022  Volume 28, Issue 3, Page(s) 439–444

    Abstract: Background: The use of surgical loupes has not been well-documented in dermatological surgery.: Objectives: An online questionnaire was developed to characterize the use of loupes in dermatological surgery.: Methods: The questionnaire was ... ...

    Abstract Background: The use of surgical loupes has not been well-documented in dermatological surgery.
    Objectives: An online questionnaire was developed to characterize the use of loupes in dermatological surgery.
    Methods: The questionnaire was circulated to the memberships of the British Society of Dermatological Surgery, the European Society of Micrographic Surgery, and the Australasian College of Dermatologists. Responses were analyzed with a mixed methods approach using quantitative data analysis and inductive content analysis.
    Results: One-hundred twenty-five valid responses were received from 20 nations. Most respondents were from England (40%; 50/125), Australia (16%; 20/125), and the Netherlands (14.4%; 18/125). Overall, 71.2% (89/125) of respondents were consultants/Facharzt/attending. Furthermore, 55.2% (69/125) of respondents were Mohs surgeons. In dermatological surgery 38.4% (48/125) of respondents used surgical loupes routinely. The mode magnification level for loupes was 2.5× (67.5%; 27/40), with 3× second place (12.5%; 5/40). Exactly half (20/40) used through-the-lens style loupes and 40% (16/40) used flip-up-loupes. Inductive content analysis of the 51 free-text responses from nonloupe users uncovered several deterring factor themes, including expense (18/51), can manage without/don't need (14/51), and narrow field of view a(11/51), and uncomfortable/too heavy (9/51).
    Conclusions: This is the first time the use of surgical loupes in dermatological surgery has been internationally characterized.
    MeSH term(s) Humans ; Lenses ; Microscopy ; Surveys and Questionnaires
    Language English
    Publishing date 2022-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1229160-2
    ISSN 1600-0846 ; 0909-752X ; 1397-1344
    ISSN (online) 1600-0846
    ISSN 0909-752X ; 1397-1344
    DOI 10.1111/srt.13144
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  9. Article ; Online: An international survey characterizing Mohs tissue processing techniques and Mohs margin thresholds: how close is too close?

    Hunt, William T N / Nelson, Toby G

    Clinical and experimental dermatology

    2022  Volume 47, Issue 8, Page(s) 1472–1479

    Abstract: Background: From practice, we identified heterogeneity in Mohs micrographic surgery (MMS) specimen tissue processing techniques and specifications, and in the Mohs surgeons' assessment of MMS specimen histological tumour clearance.: Aim: By surveying ...

    Abstract Background: From practice, we identified heterogeneity in Mohs micrographic surgery (MMS) specimen tissue processing techniques and specifications, and in the Mohs surgeons' assessment of MMS specimen histological tumour clearance.
    Aim: By surveying an international cohort of Mohs surgeons, we determined to characterize variation in margin threshold assessment (number of wafers/sections free of tumour to declare tumour clearance).
    Methods: An online questionnaire was distributed to Mohs surgeons in the UK, European countries, Australia and New Zealand, assessing the background demographics of the surgeons and the technical factors involved in MMS tissue processing and posing three MMS scenarios to define margin thresholds.
    Results: In total, 114 consultant/attending-level Mohs surgeons responded, giving a response rate of 33.5% from 20 countries (including UK nations). The first scenario posed was a 20-mm cheek basal cell carcinoma (BCC) excised by MMS with a fully complete first wafer (7 μm) clear of tumour and the second wafer (after trimming interval of 50 μm) demonstrating a small dermal focus of nodular BCC; of the 58 surgeons, 16 (27.6%) would not take another stage. With a follow-up question, 16 of the 58 (27.6%) surgeons specified wanting three clear sections to declare tumour clearance. When the same scenario had a change to a 20-mm infiltrative BCC, 84.2% (48 of 57 surgeons) required a second MMS stage, with a follow-up question clarifying that a third (19 of 57) wanted three clear sections to determine clearance. For a well-differentiated 15-mm squamous cell carcinoma with the same factors there was no majority consensus, with the same proportion of surgeons (22.6%; 12 of 53) calling tumour clearance after one, two and three clear section(s) respectively. For MMS specimen processing specifications, routine sections/wafers of 5-10 μm were reported by 77.4% of respondents (48 of 62) and for trimming interval values, 78.6% (48 of 61) specified a range between 20 and 200 μm.
    Conclusion: By surveying international Mohs surgeons, we highlight surgeon background characteristics, peer-compare assessment of margin thresholds for tumour clearance across three scenarios, and delineate tissue processing and intraoperative approaches.
    MeSH term(s) Carcinoma, Basal Cell/pathology ; Carcinoma, Basal Cell/surgery ; Humans ; Margins of Excision ; Mohs Surgery/methods ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery ; Surveys and Questionnaires
    Language English
    Publishing date 2022-06-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1111/ced.15178
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  10. Article: Stenotrophomonas maltophilia

    Belzer, Annika / Weiss, Emma / Etaee, Farshid / Bunick, Christopher G / Damsky, William / Nelson, Caroline A

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 10

    Abstract: Stenotrophomonas ... ...

    Abstract Stenotrophomonas maltophilia
    Language English
    Publishing date 2022-10-12
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11101398
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