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  1. Article ; Online: Leukocytes containing lipid inclusions in congenital ichthyosis without classical Chanarin-Dorfman mutations.

    Mallet, Stéphanie / Frankel, Diane / Jonca, Nathalie / Cano, Aline / Roll, Patrice / Kaspi, Elise

    International journal of dermatology

    2024  

    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.17149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Quiz case: Abnormal haematopoietic cells in pleural effusion.

    Frankel, Diane / Kaspi, Elise / Cointe, Sylvie / Valentin, Bruno / Roll, Patrice

    Cytopathology : official journal of the British Society for Clinical Cytology

    2023  Volume 34, Issue 6, Page(s) 640–644

    Abstract: This case was presented because of the number of plasmablasts in a patient with a medical history of multiple myeloma. Flow cytometry is a "gold standard" technique for the diagnosis of haematological malignancies. This technique works for all fluids and ...

    Abstract This case was presented because of the number of plasmablasts in a patient with a medical history of multiple myeloma. Flow cytometry is a "gold standard" technique for the diagnosis of haematological malignancies. This technique works for all fluids and should be performed in effusions (pleural, pericardial, ascites) in cases of suspected haematological malignancy. Alternatively, immunohistochemistry using appropriate markers could be performed if flow cytometry is not available. This case illustrates a pleural infiltration by plasmablasts. Myelomatous cells were characterised by immunocytochemistry and flow cytometry.
    Language English
    Publishing date 2023-08-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Morphology quiz: Bronchial washing cytology from flexible bronchoscopy.

    Roll, Patrice / Frankel, Diane / Astoul, Philippe / Dutau, Hervé / Kaspi, Elise

    Cytopathology : official journal of the British Society for Clinical Cytology

    2022  Volume 33, Issue 6, Page(s) 754–756

    MeSH term(s) Bronchoalveolar Lavage ; Bronchoscopy ; Cytodiagnosis ; Cytological Techniques ; Humans ; Lung Neoplasms/pathology
    Language English
    Publishing date 2022-06-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13154
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pleural effusion in a patient with Ewing sarcoma.

    Frankel, Diane / Kaspi, Elise / Bouvier, Corinne / Roll, Patrice

    Cytopathology : official journal of the British Society for Clinical Cytology

    2021  Volume 33, Issue 1, Page(s) 138–140

    MeSH term(s) Humans ; Pleural Effusion/diagnosis ; Sarcoma ; Sarcoma, Ewing/complications ; Sarcoma, Ewing/diagnosis
    Language English
    Publishing date 2021-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.12989
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Lipid inclusions accumulation in macrophages from peritoneal effusion of a newborn.

    Kaspi, Elise / Frankel, Diane / Roll, Patrice

    EJHaem

    2020  Volume 1, Issue 2, Page(s) 392–393

    Language English
    Publishing date 2020-10-27
    Publishing country United States
    Document type Journal Article
    ISSN 2688-6146
    ISSN (online) 2688-6146
    DOI 10.1002/jha2.124
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  6. Article ; Online: Immunocytochemical Detection of ALK and ROS1 Rearrangements in Lung Cancer Cytological Samples.

    Frankel, Diane / Kaspi, Elise / Roll, Patrice

    Methods in molecular biology (Clifton, N.J.)

    2021  Volume 2279, Page(s) 157–164

    Abstract: The detection of molecular alterations such as ROS1 and ALK rearrangements is performed as part of the diagnosis of advanced-stage lung adenocarcinoma. These alterations allow the treatments with tyrosine kinase inhibitors. Cytological samples are very ... ...

    Abstract The detection of molecular alterations such as ROS1 and ALK rearrangements is performed as part of the diagnosis of advanced-stage lung adenocarcinoma. These alterations allow the treatments with tyrosine kinase inhibitors. Cytological samples are very useful as up to 40% patients are diagnosed with this type of sample. Here we describe the immunocytochemistry technique usable to reveal the overexpression of ALK or ROS1 tyrosine kinase receptors secondary to ALK and ROS1 rearrangements, respectively.
    MeSH term(s) Adenocarcinoma of Lung/diagnosis ; Adenocarcinoma of Lung/enzymology ; Adenocarcinoma of Lung/genetics ; Adenocarcinoma of Lung/pathology ; Anaplastic Lymphoma Kinase/genetics ; Anaplastic Lymphoma Kinase/metabolism ; Female ; Gene Rearrangement ; Humans ; Immunohistochemistry ; Lung Neoplasms/diagnosis ; Lung Neoplasms/enzymology ; Lung Neoplasms/genetics ; Lung Neoplasms/pathology ; Male ; Protein-Tyrosine Kinases/genetics ; Protein-Tyrosine Kinases/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism
    Chemical Substances Proto-Oncogene Proteins ; ALK protein, human (EC 2.7.10.1) ; Anaplastic Lymphoma Kinase (EC 2.7.10.1) ; Protein-Tyrosine Kinases (EC 2.7.10.1) ; ROS1 protein, human (EC 2.7.10.1)
    Language English
    Publishing date 2021-03-08
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-1278-1_12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Enigma portal: Peritoneal effusion in a patient with a myeloproliferative neoplasm.

    Frankel, Diane / Kaspi, Elise / Grosdidier, Charlotte / Arpin, Maud / Costello, Regis / Roll, Patrice

    Cytopathology : official journal of the British Society for Clinical Cytology

    2022  Volume 34, Issue 1, Page(s) 84–86

    MeSH term(s) Humans ; Neoplasms ; Myeloproliferative Disorders/complications ; Myeloproliferative Disorders/diagnosis ; Mutation
    Language English
    Publishing date 2022-11-04
    Publishing country England
    Document type Letter
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13186
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: miR-140-5p and miR-140-3p: Key Actors in Aging-Related Diseases?

    Toury, Léa / Frankel, Diane / Airault, Coraline / Magdinier, Frédérique / Roll, Patrice / Kaspi, Elise

    International journal of molecular sciences

    2022  Volume 23, Issue 19

    Abstract: microRNAs (miRNAs) are small single strand non-coding RNAs and powerful gene expression regulators. They mainly bind to the 3'UTR sequence of targeted mRNA, leading to their degradation or translation inhibition. ...

    Abstract microRNAs (miRNAs) are small single strand non-coding RNAs and powerful gene expression regulators. They mainly bind to the 3'UTR sequence of targeted mRNA, leading to their degradation or translation inhibition.
    MeSH term(s) 3' Untranslated Regions ; Biomarkers ; MicroRNAs/genetics ; MicroRNAs/metabolism ; RNA, Long Noncoding ; RNA, Messenger
    Chemical Substances 3' Untranslated Regions ; Biomarkers ; MicroRNAs ; RNA, Long Noncoding ; RNA, Messenger
    Language English
    Publishing date 2022-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231911439
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  9. Article ; Online: Transformation from lung adenocarcinoma to combined small cell carcinoma in pleural effusion after treatment with osimertinib.

    Frankel, Diane / Kaspi, Elise / Liprandi, Agnès / Dales, Jean-Philippe / Roll, Patrice

    Cytopathology : official journal of the British Society for Clinical Cytology

    2022  Volume 33, Issue 5, Page(s) 633–635

    MeSH term(s) Acrylamides ; Adenocarcinoma of Lung/drug therapy ; Aniline Compounds ; Carcinoma, Small Cell ; Humans ; Indoles ; Lung Neoplasms/drug therapy ; Lung Neoplasms/pathology ; Pleural Effusion ; Pleural Effusion, Malignant/drug therapy ; Pleural Effusion, Malignant/pathology ; Pyrimidines
    Chemical Substances Acrylamides ; Aniline Compounds ; Indoles ; Pyrimidines ; osimertinib (3C06JJ0Z2O)
    Language English
    Publishing date 2022-06-24
    Publishing country England
    Document type Case Reports
    ZDB-ID 1034190-0
    ISSN 1365-2303 ; 0956-5507 ; 1350-4037
    ISSN (online) 1365-2303
    ISSN 0956-5507 ; 1350-4037
    DOI 10.1111/cyt.13156
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cytological Samples: An Asset for the Diagnosis and Therapeutic Management of Patients with Lung Cancer.

    Frankel, Diane / Nanni, Isabelle / Ouafik, L'Houcine / Greillier, Laurent / Dutau, Hervé / Astoul, Philippe / Daniel, Laurent / Kaspi, Elise / Roll, Patrice

    Cells

    2023  Volume 12, Issue 5

    Abstract: Background: Lung cancer has become the leading cause of cancer death for men and women. Most patients are diagnosed at an advanced stage when surgery is no longer a therapeutic option. At this stage, cytological samples are often the less invasive ... ...

    Abstract Background: Lung cancer has become the leading cause of cancer death for men and women. Most patients are diagnosed at an advanced stage when surgery is no longer a therapeutic option. At this stage, cytological samples are often the less invasive source for diagnosis and the determination of predictive markers. We assessed the ability of cytological samples to perform diagnosis, and to establish molecular profile and PD-L1 expression, which are essential for the therapeutic management of patients.
    Methods: We included 259 cytological samples with suspected tumor cells and assessed the ability to confirm the type of malignancy by immunocytochemistry. We summarized results of molecular testing by next generation sequencing (NGS) and PD-L1 expression from these samples. Finally, we analyzed the impact of these results in the patient management.
    Results: Among the 259 cytological samples, 189 concerned lung cancers. Of these, immunocytochemistry confirmed the diagnosis in 95%. Molecular testing by NGS was obtained in 93% of lung adenocarcinomas and non-small cell lung cancer. PD-L1 results were obtained in 75% of patients tested. The results obtained with cytological samples led to a therapeutic decision in 87% of patients.
    Conclusion: Cytological samples are obtained by minimally invasive procedures and can provide enough material for the diagnosis and therapeutic management in lung cancer patients.
    MeSH term(s) Male ; Humans ; Female ; Lung Neoplasms/pathology ; Carcinoma, Non-Small-Cell Lung/pathology ; B7-H1 Antigen/metabolism ; Adenocarcinoma of Lung ; Immunohistochemistry
    Chemical Substances B7-H1 Antigen
    Language English
    Publishing date 2023-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12050754
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