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  1. Book: Pharmacological treatment of epilepsy

    Leppik, Ilo E.

    current trade-offs and the role of levetiracetam

    (Epilepsia ; 42, Suppl. 4)

    2001  

    Author's details guest ed. Ilo E. Leppik
    Series title Epilepsia ; 42, Suppl. 4
    Collection
    Language English
    Size 45 S. : graph. Darst.
    Publisher Blackwell Science
    Publishing place Malden, MA
    Publishing country United States
    Document type Book
    HBZ-ID HT013154271
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 517 -42,Suppl.4- not available for loan Zeitschriften-Lesesaal

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  2. Article ; Online: Status epilepticus in the elderly.

    Leppik, Ilo E

    Epilepsia

    2018  Volume 59 Suppl 2, Page(s) 140–143

    Abstract: Children and the elderly (≥60 years of age) have the highest incidence of status epilepticus (SE). Because of their general health, elderly individuals are much more likely than younger (<60 years of age) persons to have more severe consequences from ... ...

    Abstract Children and the elderly (≥60 years of age) have the highest incidence of status epilepticus (SE). Because of their general health, elderly individuals are much more likely than younger (<60 years of age) persons to have more severe consequences from seizures. The incidence of SE is 15.5/100 000 in the 60-69 age group, 21.5/100 000 in the 70-79 age group and 25.9/100 000 in persons 80 and older. The most common cause in the elderly is acute symptomatic, with stroke and hypoxia the most frequent. The overall mortality of SE is quite high and occurs early, often within the first few days, and is related to the cause, with mortality of more than 80% in persons with anoxia. Although the cause of SE is an important factor in mortality, the aging body and brain may contribute to an unfavorable outcome. Treatment in the elderly is essentially the same as in younger adults with benzodiazepines (lorazepam, diazepam, clonazepam) and longer acting antiseizure drugs (phenytoin, fosphenytoin, valproate, levetiracetam, and lacosamide. At this time there are no evidence-based studies regarding Axis 2 (etiology) and Axis 4 (age). All current interventions for SE involve antiseizure drugs that were developed for treatment of chronic epilepsy. Treatments should be developed that are more specific for the various etiologies and involve drugs that work on the underlying cause of the SE.
    MeSH term(s) Age Distribution ; Aged ; Aged, 80 and over ; Aging ; Anticonvulsants/therapeutic use ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Status Epilepticus/drug therapy ; Status Epilepticus/epidemiology ; Status Epilepticus/etiology ; Status Epilepticus/mortality
    Chemical Substances Anticonvulsants
    Language English
    Publishing date 2018-08-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 216382-2
    ISSN 1528-1167 ; 0013-9580
    ISSN (online) 1528-1167
    ISSN 0013-9580
    DOI 10.1111/epi.14497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 517: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 475: Show issues

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  3. Book: Contemporary epilepsy evaluation and therapy / 1

    Leppik, Ilo E.

    (... ; [9, Beil.])

    1996  

    Author's details ed. Ilo E. Leppik
    Series title ... ; [9, Beil.]
    Journal of epilepsy
    Contemporary epilepsy evaluation and therapy
    Collection Journal of epilepsy
    Contemporary epilepsy evaluation and therapy
    Language English
    Size 25 S. : Ill., graph. Darst.
    Publisher Excerpta Medica
    Publishing place Belle Mead, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT007407305
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 2764 -[9,Beil.]- not available for loan Zeitschriften-Lesesaal

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  4. Article ; Online: New Onset (Incidence) of Epilepsy and Seizures in Nursing Home Residents.

    Leppik, Ilo E / Birnbaum, Angela K / Svensden, Kenneth / Eberly, Lynn E

    Journal of the American Medical Directors Association

    2022  Volume 23, Issue 9, Page(s) 1589.e11–1589.e15

    Abstract: Objective: The point prevalence of epilepsy is high in nursing homes (NH), but the incidence of epilepsy after admission is unknown. This study was done to determine the incidence of epilepsy/seizure (epi/sz) comorbid with other conditions in older ... ...

    Abstract Objective: The point prevalence of epilepsy is high in nursing homes (NH), but the incidence of epilepsy after admission is unknown. This study was done to determine the incidence of epilepsy/seizure (epi/sz) comorbid with other conditions in older adult NH residents.
    Design: Retrospective evaluation of Minimum Data Set records to identify new onset epi/sz in NH residents.
    Setting and participants: Five cross-sectional cohorts of all residents in any Medicare/Medicaid certified NH in the United States on July 15 of each year 2003-2007.
    Measures: Epi/sz was identified by International Classification of Diseases, Ninth Revision codes (345.xx or 780.39) or check box on the Minimum Data Set. Those with no such code on admission and with 1 to 3 plus years of follow-up (n = 3,609,422) were followed through 2007 or end of stay.
    Results: Overall incidence of epi/sz was 16.42/1000 patient years (PY). Incidence was highest in the first year after admission and declined thereafter. There were more women (n = 2,523,951) than men (n = 1,089,631), but men had a higher incidence (21.17/1000PY) compared with women (14.81/1000PY). Although the 65‒74 years of age cohort included fewer residents (n = 594,722) compared with the age 85 years + cohort (n = 1,520,167), the younger residents had the highest incidence (28.53/1000 PY) compared with the oldest, 10.22/1000 PY for the age 85+ years cohort. The highest incidences were among those with brain tumor (122.55/1000PY), followed by head injury (45.66/1000PY). Overall, 714,340 had a diagnosis of stroke, and incidence was 27.52/1000PY. Those with none of selected risk factors had an overall incidence of 12.45/1000PY.
    Conclusions and implications: The incidence of epi/sz in older individuals after admission to a NH is high. There is a need to develop practice approaches to best manage this large cohort. There does not appear to be a uniform approach to managing new onset epilepsy in NHs at this time. Studies to develop evidence for practice guidelines are needed.
    MeSH term(s) Aged ; Aged, 80 and over ; Cross-Sectional Studies ; Epilepsy/epidemiology ; Female ; Humans ; Incidence ; Male ; Medicare ; Nursing Homes ; Retrospective Studies ; Seizures/epidemiology ; United States/epidemiology
    Language English
    Publishing date 2022-06-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 2171030-2
    ISSN 1538-9375 ; 1525-8610
    ISSN (online) 1538-9375
    ISSN 1525-8610
    DOI 10.1016/j.jamda.2022.06.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5971: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Book ; Conference proceedings: Tiagabine - the art of epilepsy care

    Leppik, Ilo E.

    a satellite symposium to the 21st International Epilepsy Congress, Sydney, Australia, September 2, 1995

    (Epilepsia ; 36, Suppl. 6)

    1995  

    Event/congress International Epilepsy Congress (21, 1995, Sydney)
    Author's details guest ed. Ilo E. Leppik
    Series title Epilepsia ; 36, Suppl. 6
    Collection
    Keywords Nipecotic Acids / therapeutic use / congresses ; Epilepsy / drug therapy / congresses ; Epilepsie ; Therapie
    Subject Medizinische Behandlung ; Behandlung ; Krankenbehandlung ; Fallsucht
    Language English
    Size S26 S. : graph. Darst.
    Publisher Lippincott-Raven
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT006884006
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 517 -36,Suppl.6- not available for loan Zeitschriften-Lesesaal

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  6. Book ; Conference proceedings: Epilepsy

    Leppik, Ilo E.

    diagnostic and treatment strategies for the next decade

    (Epilepsia ; 32, Suppl. 5)

    1991  

    Event/congress Merritt Putnam Symposium (10, 1990, SanDiegoCalif.)
    Author's details Tenth Annual Merritt-Putnam Symposium, November 15, 1990, San Diego, California. Guest ed. Ilo E. Leppik
    Series title Epilepsia ; 32, Suppl. 5
    Collection
    Keywords Epilepsy / diagnosis / congresses ; Epilepsy / drug therapy / congresses
    Language English
    Size VIII, S86 S. : Ill., graph. Darst.
    Publisher Raven Pr
    Publishing place New York
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT004319717
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 517 -32,Suppl.5- verfügbar in Königswinter Königswinter

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  7. Book ; Conference proceedings: Epilepsy through life

    Leppik, Ilo E.

    recent advances in understanding and treating epilepsy during pregnancy, childhood, adulthood, and old age ; December 7, 1991, Philadelphia, Pennsylvania

    (Epilepsia ; 33, Suppl. 4 = Spec. iss.)

    1992  

    Event/congress Merritt Putnam Symposium (11, 1991, PhiladelphiaPa.)
    Author's details Eleventh Annual Merritt-Putnam Symposium. Guest ed. Ilo E. Leppik
    Series title Epilepsia ; 33, Suppl. 4 = Spec. iss.
    Collection
    Keywords Epilepsy / drug therapy / congresses
    Language English
    Size VIII, S67 S. : Ill., graph. Darst.
    Publisher Raven Press
    Publishing place New York
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT004446529
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 517 -33,Suppl.4- verfügbar in Königswinter Königswinter

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  8. Book ; Conference proceedings: Status epilepticus in perspective

    Leppik, Ilo E.

    [this symposium was held in Chicago on April 12, 1989]

    (Neurology ; 40, Suppl. 2)

    1990  

    Author's details Ilo E. Leppik, suppl. ed
    Series title Neurology ; 40, Suppl. 2
    Collection
    Keywords Status Epilepticus / congresses
    Language English
    Size 51 Bl. : graph. Darst.
    Publisher Advanstar Communications
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Conference proceedings
    Note Kopie
    HBZ-ID HT006513877
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Ui II Zs 153 -40,5,Suppl.2- verfügbar in Königswinter Königswinter

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  9. Book ; Conference proceedings: A Symposium the Oral Manifestations of Gingival Hyperplasia

    Leppik, Ilo E.

    March 6, 1990, [Philadelphia, Pennsylvania]

    (The compendium of continuing education in dentistry : Supplement ; 14)

    1990  

    Title variant The oral manifestations of gingival hyperplasia
    Institution Symposium the Oral Manifestations of Gingival Hyperplasia
    Author's details Ilo E. Leppik
    Series title The compendium of continuing education in dentistry : Supplement ; 14
    The Compendium of continuing education in dentistry
    The compendium of continuing education in dentistry ; Supplement
    Collection The Compendium of continuing education in dentistry
    The compendium of continuing education in dentistry ; Supplement
    Keywords Gingival Hyperplasia / congresses
    Size S490 - S519 S. : Ill.
    Publisher Dental Learning Systems
    Publishing place Newtown, PA
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT003619814
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs B 2795 -Suppl.14- verfügbar in Königswinter Königswinter

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  10. Book ; Conference proceedings: Epileptic syndromes

    Leppik, Ilo E.

    genetic, diagnostic, and therapeutic aspects ; December 7, 1989, Boston, Massachusetts

    (Epilepsia ; 31, Suppl. 3)

    1990  

    Event/congress Merritt Putnam Symposium (9, 1989, BostonMass.)
    Author's details Ninth Annual Merritt-Putnam Symposium. Guest ed. Ilo E.: Leppik
    Series title Epilepsia ; 31, Suppl. 3
    Collection
    Keywords Epilepsy / congresses
    Language English
    Size VIII, S79 S. : Ill., graph. Darst.
    Publisher Raven Pr
    Publishing place New York
    Publishing country United States
    Document type Book ; Conference proceedings
    HBZ-ID HT003711963
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 517 -31,Suppl.3- verfügbar in Königswinter Königswinter

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