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Article: Does millet consumption contribute to raising blood hemoglobin levels compared to regular refined staples?: a systematic review and meta-analysis.

Anitha, Seetha / Tsusaka, Takuji W / Givens, D Ian / Kane-Potaka, Joanna / Botha, Rosemary / Sulaiman, Nur Liana Binti / Upadhyay, Shweta / Vetriventhan, Mani / Rajendran, Ananthan / Parasannanavar, Devraj J / Longvah, Thingnganing / Subramaniam, Kowsalya / Bhandari, Raj Kumar

Frontiers in nutrition

2024 Volume 11, Page(s) 1305394

Abstract: Millets are recognized for their health and nutritional values, and the United Nations declared 2023 the International Year of Millets. Among the several health and nutritional benefits of millets, their impact on hemoglobin concentration is important ... ...

Abstract	Millets are recognized for their health and nutritional values, and the United Nations declared 2023 the International Year of Millets. Among the several health and nutritional benefits of millets, their impact on hemoglobin concentration is important since anemia is a major public health issue in many countries. To investigate the effect of millet (including sorghum) consumption on hemoglobin concentration in the blood, a systematic review and meta-analysis were conducted. Thirteen published studies featuring randomized control trials involving 590 individuals in the intervention group and 549 control individuals were eligible for the meta-analysis. The difference-in-differences analysis revealed highly significant (
Language	English
Publishing date	2024-02-12
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2024.1305394
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Epilepsy: addressing the transition from pediatric to adult care.

Rajendran, Seetha / Iyer, Anand

Adolescent health, medicine and therapeutics

2016 Volume 7, Page(s) 77–87

Abstract: Adolescence is a period of rapid change, both physical and psychosocial for any young person. It can be challenging when they have ongoing health problems and when their care needs to be transitioned to the adult health care system. Transition should be ... ...

Abstract	Adolescence is a period of rapid change, both physical and psychosocial for any young person. It can be challenging when they have ongoing health problems and when their care needs to be transitioned to the adult health care system. Transition should be a planned process of addressing the medical and associated comorbid conditions from pediatric to adult care in a coordinated manner. In most cases, the young person and their family are well known to the pediatrics services and have built a relationship based on trust and often friendship over many years. Understandably, there is significant apprehension about moving from this familiar setting to the unknown adult services. Apart from having a sound knowledge of specific childhood epileptic conditions and associated comorbid disorders, it is important that both the pediatric and adult epilepsy teams are motivated to provide a successful and safe transition for these patients. It is essential that transition is seen as a continual process and not as a single event, and good preparation is the key to its success. It is also important that general practitioners are closely engaged to ensure successful transition. An overview of how to effectively address transition in epilepsy, different models of transition, transition of relevant epilepsies, and their management is discussed.
Language	English
Publishing date	2016-06-27
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	2587456-1
ISSN	1179-318X
ISSN	1179-318X
DOI	10.2147/AHMT.S79060
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Are Millets More Effective in Managing Hyperlipidaemia and Obesity than Major Cereal Staples? A Systematic Review and Meta-Analysis

Seetha Anitha / Takuji W. Tsusaka / Rosemary Botha / Joanna Kane-Potaka / David Ian Givens / Ananthan Rajendran / Raj Kumar Bhandari

Sustainability, Vol 14, Iss 6659, p

2022 Volume 6659

Abstract: Millets are important staples across developing countries in Asia and Africa. A previous systematic review and meta-analysis showed that eating millets significantly controlled hyperlipidaemia and obesity by focusing on a comparison of pre- and post- ... ...

Abstract	Millets are important staples across developing countries in Asia and Africa. A previous systematic review and meta-analysis showed that eating millets significantly controlled hyperlipidaemia and obesity by focusing on a comparison of pre- and post-intervention measurements. This study further provides meta-analysis of the effects of the consumption of millets on hyperlipidaemia and obesity by analysing millets against other staple grains using the difference-in-differences method, where the effects were computed on the Standardised Mean Difference scale. Thus, only studies that included a control group as well as the baseline were included. The results from twelve eligible studies on blood lipid profile show significant ( p < 0.05) favourable effects of consuming millets compared to other staples (rice, wheat, and quinoa). Specifically, the effects on total cholesterol, triacylglycerol, and very low-density lipoprotein cholesterol levels were −0.44, −0.29, and −0.41, respectively ( p < 0.05), while the effect on the high-density lipoprotein cholesterol level was +0.59 ( p < 0.05). In addition, the effects on low-density lipoprotein cholesterol and the body mass index were −0.60 and −0.29, respectively, with p = 0.06 each. While this study strengthens the evidence that the consumption of millets contributes to reducing the risks of hyperlipidaemia, and therefore cardiovascular diseases, more detailed and rigorous studies are recommended.
Keywords	lipid profile ; millet consumption ; nutrition ; staple crop ; hyperlipidaemia ; obesity ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	630
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Can Millet Consumption Help Manage Hyperlipidemia and Obesity?: A Systematic Review and Meta-Analysis.

Anitha, Seetha / Botha, Rosemary / Kane-Potaka, Joanna / Givens, D Ian / Rajendran, Ananthan / Tsusaka, Takuji W / Bhandari, Raj Kumar

Frontiers in nutrition

2021 Volume 8, Page(s) 700778

Abstract: Many health benefits of millets (defined broadly to also include sorghum) have been advocated, including their roles in managing and preventing diabetes; however, the effects of millets on hyperlipidemia (high lipid levels) have been underrecognized. A ... ...

Abstract	Many health benefits of millets (defined broadly to also include sorghum) have been advocated, including their roles in managing and preventing diabetes; however, the effects of millets on hyperlipidemia (high lipid levels) have been underrecognized. A systematic review and meta-analysis were conducted to collate available evidence of the impacts of millets consumption on lipid profile, namely total cholesterol (TC), triacylglycerol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and very-low-density lipoprotein cholesterol (VLDL-C). The results from 19 studies showed that the consumption of millets for periods as short as 21 days to 4 months reduced levels of TC, triacylglycerol, LDL-C, and VLDL-C (
Language	English
Publishing date	2021-08-17
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2021.700778
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Can Feeding a Millet-Based Diet Improve the Growth of Children?-A Systematic Review and Meta-Analysis.

Anitha, Seetha / Givens, David Ian / Subramaniam, Kowsalya / Upadhyay, Shweta / Kane-Potaka, Joanna / Vogtschmidt, Yakima D / Botha, Rosemary / Tsusaka, Takuji W / Nedumaran, Swamikannu / Rajkumar, Hemalatha / Rajendran, Ananthan / Parasannanavar, Devraj J / Vetriventhan, Mani / Bhandari, Raj Kumar

Nutrients

2022 Volume 14, Issue 1

Abstract: Undernutrition, such as stunting and underweight, is a major public health concern, which requires multi-sectoral attention. Diet plays a key role in growth and should optimally supply all required nutrients to support the growth. While millets (defined ... ...

Abstract	Undernutrition, such as stunting and underweight, is a major public health concern, which requires multi-sectoral attention. Diet plays a key role in growth and should optimally supply all required nutrients to support the growth. While millets (defined broadly to include sorghum) are traditional foods, and climate smart nutritious crops, which are grown across Africa and Asia, they have not been mainstreamed like rice, wheat, and maize. Diversifying staples with millets can potentially provide more macro and micro nutrients, compared to the mainstream crops. However, there is little known scientific evidence to prove millets' efficacy on growth. Therefore, a systematic review and meta-analysis was conducted to collate evidence of the benefits of millets in improving the growth of children. Eight eligible randomized feeding trials were included in the meta-analysis. Results from the randomized effect model showed a significant effect (
MeSH term(s)	Diet/methods ; Edible Grain ; Humans ; Malnutrition/etiology ; Malnutrition/prevention & control ; Millets ; Nutritional Status ; Oryza ; Sorghum
Language	English
Publishing date	2022-01-05
Publishing country	Switzerland
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14010225
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: A systematic review and meta-analysis of the potential of millets for managing and reducing the risk of developing diabetes mellitus

Anitha, Seetha / Kane-Potaka, Joanna / Tsusaka, Takuji W. / Botha, Rosemary / Rajendran, Ananthan

Frontiers in Nutrition 8: 687428

2021

Abstract: Millets (including sorghum) are known to be highly nutritious besides having a low carbon footprint and the ability to survive in high temperatures with minimal water. Millets are widely recognised as having a low Glycaemic Index (GI) helping to manage ... ...

Abstract	Millets (including sorghum) are known to be highly nutritious besides having a low carbon footprint and the ability to survive in high temperatures with minimal water. Millets are widely recognised as having a low Glycaemic Index (GI) helping to manage diabetes. This systematic review and meta-analyzes across the different types of millets and different forms of processing/cooking collated all evidences. Of the 65 studies that were collected globally, 39 studies with 111 observations were used to analyze GI outcomes and 56 studies were used to analyze fasting, post-prandial glucose level, insulin index and HbA1c outcomes in a meta-analysis. It is evident from the descriptive statistics that the mean GI of millets is 52.7 ± 10.3, which is about 36% lower than in typical staples of milled rice (71.7 ± 14.4) and refined wheat (74.2 ± 14.9). The descriptive, meta and regression analyses revealed that Job's tears, fonio, foxtail, barnyard, and teff were the millets with low mean GI (<55) that are more effective (35–79%) in reducing dietary GI than the control samples. Millets with intermediate GI (55–69) are pearl millet, finger millet, kodo millet, little millet, and sorghum which have a 13–35% lower GI than the control with high GI (>69). A meta-analysis also showed that all millets had significantly (p < 0.01) lower GI than white rice, refined wheat, standard glucose or white wheat bread except little millet which had inconsistent data. Long term millet consumption lowered fasting and post-prandial blood glucose levels significantly (p < 0.01) by 12 and 15%, respectively, in diabetic subjects. There was a significant reduction in HbA1c level (from 6.65 ± 0.4 to 5.67 ± 0.4%) among pre-diabetic individuals (p < 0.01) who consumed millets for a long period. Minimally processed millets were 30% more effective in lowering GI of a meal compared to milled rice and refined wheat. In conclusion, millets can be beneficial in managing and reducing the risk of developing diabetes and could therefore be used to ...
Keywords	WORLD ; millets ; diabetes ; health ; public health ; nutrition ; glucose ; rice ; wheat ; grain
Subject code	571
Language	English
Publisher	Frontiers Media S.A.
Publishing country	us
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Millets Can Have a Major Impact on Improving Iron Status, Hemoglobin Level, and in Reducing Iron Deficiency Anemia-A Systematic Review and Meta-Analysis.

Anitha, Seetha / Kane-Potaka, Joanna / Botha, Rosemary / Givens, D Ian / Sulaiman, Nur Liana Binti / Upadhyay, Shweta / Vetriventhan, Mani / Tsusaka, Takuji W / Parasannanavar, Devraj J / Longvah, Thingnganing / Rajendran, Ananthan / Subramaniam, Kowsalya / Bhandari, Raj Kumar

Frontiers in nutrition

2021 Volume 8, Page(s) 725529

Abstract: The prevalence of iron deficiency anemia is highest among low and middle-income countries. Millets, including sorghum, are a traditional staple in many of these countries and are known to be rich in iron. However, a wide variation in the iron composition ...

Abstract	The prevalence of iron deficiency anemia is highest among low and middle-income countries. Millets, including sorghum, are a traditional staple in many of these countries and are known to be rich in iron. However, a wide variation in the iron composition of millets has been reported, which needs to be understood in consonance with its bioavailability and roles in reducing anemia. This systematic review and meta-analysis were carried out to analyze the scientific evidence on the bioavailability of iron in different types of millets, processing, and the impact of millet-based food on iron status and anemia. The results indicated that iron levels in the millets used to study iron bioavailability (both
Language	English
Publishing date	2021-10-14
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2021.725529
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Systematic Review and Meta-Analysis of the Potential of Millets for Managing and Reducing the Risk of Developing Diabetes Mellitus.

Anitha, Seetha / Kane-Potaka, Joanna / Tsusaka, Takuji W / Botha, Rosemary / Rajendran, Ananthan / Givens, D Ian / Parasannanavar, Devraj J / Subramaniam, Kowsalya / Prasad, Kanaka Durga Veera / Vetriventhan, Mani / Bhandari, Raj Kumar

Frontiers in nutrition

2021 Volume 8, Page(s) 687428

Abstract	Millets (including sorghum) are known to be highly nutritious besides having a low carbon footprint and the ability to survive in high temperatures with minimal water. Millets are widely recognised as having a low Glycaemic Index (GI) helping to manage diabetes. This systematic review and meta-analyzes across the different types of millets and different forms of processing/cooking collated all evidences. Of the 65 studies that were collected globally, 39 studies with 111 observations were used to analyze GI outcomes and 56 studies were used to analyze fasting, post-prandial glucose level, insulin index and HbA1c outcomes in a meta-analysis. It is evident from the descriptive statistics that the mean GI of millets is 52.7 ± 10.3, which is about 36% lower than in typical staples of milled rice (71.7 ± 14.4) and refined wheat (74.2 ± 14.9). The descriptive, meta and regression analyses revealed that Job's tears, fonio, foxtail, barnyard, and teff were the millets with low mean GI (<55) that are more effective (35-79%) in reducing dietary GI than the control samples. Millets with intermediate GI (55-69) are pearl millet, finger millet, kodo millet, little millet, and sorghum which have a 13-35% lower GI than the control with high GI (>69). A meta-analysis also showed that all millets had significantly (
Language	English
Publishing date	2021-07-28
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2021.687428
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Can Feeding a Millet-Based Diet Improve the Growth of Children?—A Systematic Review and Meta-Analysis

Anitha, Seetha / Givens, David Ian / Subramaniam, Kowsalya / Upadhyay, Shweta / Kane-Potaka, Joanna / Vogtschmidt, Yakima D. / Botha, Rosemary / Tsusaka, Takuji W. / Nedumaran, Swamikannu / Rajkumar, Hemalatha / Rajendran, Ananthan / Parasannanavar, Devraj J. / Vetriventhan, Mani / Bhandari, Raj Kumar

Nutrients. 2022 Jan. 05, v. 14, no. 1

2022

Abstract	Undernutrition, such as stunting and underweight, is a major public health concern, which requires multi-sectoral attention. Diet plays a key role in growth and should optimally supply all required nutrients to support the growth. While millets (defined broadly to include sorghum) are traditional foods, and climate smart nutritious crops, which are grown across Africa and Asia, they have not been mainstreamed like rice, wheat, and maize. Diversifying staples with millets can potentially provide more macro and micro nutrients, compared to the mainstream crops. However, there is little known scientific evidence to prove millets’ efficacy on growth. Therefore, a systematic review and meta-analysis was conducted to collate evidence of the benefits of millets in improving the growth of children. Eight eligible randomized feeding trials were included in the meta-analysis. Results from the randomized effect model showed a significant effect (p < 0.05) of millet-based diets on mean height (+28.2%) (n = 8), weight (n = 9) (+26%), mid upper arm circumference (n = 5) (+39%) and chest circumference (n = 5) (+37%) in comparison to regular rice-based diets over for the period of 3 months to 4.5 years, which was based on largely substituting rice with millets. When an enhanced and diverse diet was served, replacing rice with millet had only minimal growth improvement on chest circumference (p < 0.05). The quality assessment using GRADE shows that the evidence used for this systematic review and meta-analysis had moderate quality, based on eight scoring criteria. These results demonstrate the value of adding millet as the staple for undernourished communities. Further understanding of the efficacy of millets on growth in a wider range of diets is important to develop appropriate dietary programs and improve the nutritional status of various age groups across Africa and Asia.
Keywords	arm circumference ; chest ; climate ; corn ; diet ; malnutrition ; meta-analysis ; millets ; models ; nutritional status ; public health ; rice ; systematic review ; underweight ; wheat ; Africa ; Asia
Language	English
Dates of publication	2022-0105
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2518386-2
ISSN	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14010225
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Calcium from Finger Millet—A Systematic Review and Meta-Analysis on Calcium Retention, Bone Resorption, and In Vitro Bioavailability

Seetha Anitha / David Ian Givens / Rosemary Botha / Joanna Kane-Potaka / Nur Liana Binti Sulaiman / Takuji W. Tsusaka / Kowsalya Subramaniam / Ananthan Rajendran / Devraj J. Parasannanavar / Raj Kumar Bhandari

Sustainability, Vol 13, Iss 8677, p

2021 Volume 8677

Abstract: Calcium deficiency during child growth leads to osteoporosis in later stages of life. Finger millet is one of the calcium dense foods, with three times the level of calcium than milk, and the only cereal that contains high calcium content which is ... ...

Abstract	Calcium deficiency during child growth leads to osteoporosis in later stages of life. Finger millet is one of the calcium dense foods, with three times the level of calcium than milk, and the only cereal that contains high calcium content which is consistent across different varieties (364 ± 58 mg/100 g). Thus, finger millet has potential for addressing calcium deficiency naturally. This study aimed to determine the retention and impact of finger millet calcium on bone turnover through a systematic review and meta-analysis. Three human studies were eligible for systematic review. Of these, only two were eligible for meta-analysis to assess the retention of calcium in children of 9 to 12 years. One study on bone turnover markers was not used in the meta-analysis as at least two studies are required to conduct meta-analysis. Due to the lack of complete data only four studies were eligible for meta-analysis to assess the in vitro bioavailability of calcium from unprocessed and a range of different types of processed finger millet. The result shows that there was significant retention ( p < 0.05) of 23.4 ± 2.9% calcium from finger-millet-based diet which could help bone accretion during child growth if finger-millet-based diet is consumed. The bone turnover marker study shows that the resorption of calcium reduced by 28% and 47% among peri and post-menopausal women respectively after feeding the nutria mixed grain ball. However, there is no significant change in bone formation marker. Depending on the type of processing, calcium bioavailability either increased or decreased. One in vitro study showed that calcium bioavailability from finger millet was 28.6% when boiled, whereas three studies on processing show that certain processing can double the calcium bioavailability to 61.4%. Irrespective of the type of processing, finger millets contribute to high calcium retention and extremely high bioavailable calcium and could be useful for healthy growth and in dealing with complications related to calcium deficiency.
Keywords	finger millet based diet ; calcium deficiency ; bioavailable calcium ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	150
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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