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Article ; Online: Application of mobility training methods in sporting populations: A systematic review of performance adaptations.

Skopal, Lauren K / Drinkwater, Eric J / Behm, David G

2024 Volume 42, Issue 1, Page(s) 46–60

Abstract: This systematic review investigates influences of mobility training in sporting populations on performance outcomes. The search strategy involved Embase, MEDLINE Complete, Sports Discus and manual search from inception to March 2022. Mobility training ... ...

Abstract	This systematic review investigates influences of mobility training in sporting populations on performance outcomes. The search strategy involved Embase, MEDLINE Complete, Sports Discus and manual search from inception to March 2022. Mobility training studies with a minimum three-week, or 10-session duration in healthy sporting populations of any age were included. Twenty-two studies comprising predominantly young adult or junior athletes were analysed from 319 retrieved articles. Performance outcomes were strength, speed, change of direction, jumping, balance, and sport-specific skills. Fifteen studies randomized participants with only four indicating systematic allocation concealment and blinding of outcomes assessors in only one study. In 20 of 22 studies mobility training was of some benefit or helped to maintain sports performance to a larger degree than control conditions. Control conditions, which were generally no activity conditions, were primarily non-significant. The majority of evidence suggests that a range of mobility training methods may improve key sports performance variables or are unlikely to impair performance over time. Therefore, coaches can consider the potential benefits of including comprehensive mobility programmes with minimal risk of impairing performance. Higher-quality studies in homogenous populations are necessary to confirm performance changes.
MeSH term(s)	Young Adult ; Humans ; Athletic Performance ; Athletes ; Health Status
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	995528-8
ISSN	1466-447X ; 0264-0414
ISSN (online)	1466-447X
ISSN	0264-0414
DOI	10.1080/02640414.2024.2321006
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Zs.A 2388: Show issues

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Article ; Online: Prolonged static stretching increases the magnitude and decreases the complexity of knee extensor muscle force fluctuations.

Pethick, Jamie / Moran, Jason / Behm, David G

PloS one

2023 Volume 18, Issue 7, Page(s) e0288167

Abstract: Static stretching decreases maximal muscle force generation in a dose-response manner, but its effects on the generation of task-relevant and precise levels of submaximal force, i.e. force control, is unclear. We investigated the effect of acute static ... ...

Abstract	Static stretching decreases maximal muscle force generation in a dose-response manner, but its effects on the generation of task-relevant and precise levels of submaximal force, i.e. force control, is unclear. We investigated the effect of acute static stretching on knee extensor force control, quantified according to both the magnitude and complexity of force fluctuations. Twelve healthy participants performed a series of isometric knee extensor maximal voluntary contractions (MVCs) and targeted intermittent submaximal contractions at 25, 50 and 75% MVC (3 x 6 seconds contraction separated by 4 seconds rest, with 60 seconds rest between each intensity) prior to, and immediately after, one of four continuous static stretch conditions: 1) no stretch; 2) 30-second stretch; 3) 60-second stretch; 4) 120-second stretch. The magnitude of force fluctuations was quantified using the standard deviation (SD) and coefficient of variation (CV), while the complexity of fluctuations was quantified using approximate entropy (ApEn) and detrended fluctuation analysis (DFA) α. These measures were calculated using the steadiest 5 seconds of the targeted submaximal contractions at each intensity (i.e., that with the lowest SD). Significant decreases in MVC were evident following the 30, 60 and 120-second stretch conditions (all P < 0.001), with a significant correlation observed between stretch duration and the magnitude of decrease in MVC (r = -0.58, P < 0.001). The 120-second stretch resulted in significant increases in SD at 50% MVC (P = 0.007) and CV at 50% (P = 0.009) and 75% MVC (P = 0.005), and a significant decrease in ApEn at 75% MVC (P < 0.001). These results indicate that the negative effects of prolonged static stretching extend beyond maximal force generation tasks to those involving generation of precise levels of force during moderate- to high-intensity submaximal contractions.
MeSH term(s)	Humans ; Muscle Stretching Exercises ; Muscle Fatigue/physiology ; Knee/physiology ; Muscle, Skeletal/physiology ; Knee Joint/physiology ; Isometric Contraction/physiology ; Electromyography/methods ; Muscle Contraction/physiology
Language	English
Publishing date	2023-07-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0288167
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: TRPV4 antagonists: a patent review (2015-2020).

Lawhorn, Brian G / Brnardic, Edward J / Behm, David J

Expert opinion on therapeutic patents

2021 Volume 31, Issue 9, Page(s) 773–784

Abstract: ... ...

Abstract	Introduction
MeSH term(s)	Animals ; Benzimidazoles/pharmacology ; Drug Development ; Drug Discovery ; Humans ; Patents as Topic ; Spiro Compounds/pharmacology ; TRPV Cation Channels/antagonists & inhibitors ; TRPV Cation Channels/metabolism
Chemical Substances	Benzimidazoles ; GSK2798745 ; Spiro Compounds ; TRPV Cation Channels ; TRPV4 protein, human
Language	English
Publishing date	2021-03-24
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	1186201-4
ISSN	1744-7674 ; 0962-2594 ; 1354-3776
ISSN (online)	1744-7674
ISSN	0962-2594 ; 1354-3776
DOI	10.1080/13543776.2021.1903432
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Zs.A 3962: Show issues

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Article: Sex differences in stretch-induced hypertrophy, maximal strength and flexibility gains.

Warneke, Konstantin / Zech, Astrid / Wagner, Carl-Maximilian / Konrad, Andreas / Nakamura, Masatoshi / Keiner, Michael / Schoenfeld, Brad J / Behm, David George

Frontiers in physiology

2023 Volume 13, Page(s) 1078301

Abstract: Introduction: ...

Abstract	Introduction:
Language	English
Publishing date	2023-01-04
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564217-0
ISSN	1664-042X
ISSN	1664-042X
DOI	10.3389/fphys.2022.1078301
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Article ; Online: Recent advances in TRPV4 agonists and antagonists.

Lawhorn, Brian G / Brnardic, Edward J / Behm, David J

Bioorganic & medicinal chemistry letters

2020 Volume 30, Issue 8, Page(s) 127022

Abstract: TRPV4 is a ubiquitously expressed, non-selective cation channel activated by a range of stimuli including hypotonicity, temperature, pH, stretch and endogenous ligands. Agents that modulate TRPV4 are sought as potential therapeutics for the treatment of ... ...

Abstract	TRPV4 is a ubiquitously expressed, non-selective cation channel activated by a range of stimuli including hypotonicity, temperature, pH, stretch and endogenous ligands. Agents that modulate TRPV4 are sought as potential therapeutics for the treatment of many diseases including osteoarthritis, respiratory illnesses, gastrointestinal disorders, pain and congestive heart failure. In recent years, significant advances in TRPV4 drug discovery have been realized as at least seven novel TRPV4 agonist or antagonist templates were reported and the first selective TRPV4 antagonist was evaluated in early clinical trials.
MeSH term(s)	Biological Products/chemistry ; Biological Products/pharmacology ; Drug Discovery ; Humans ; Models, Molecular ; Molecular Structure ; Phorbols/chemistry ; Phorbols/pharmacology ; TRPV Cation Channels/agonists ; TRPV Cation Channels/antagonists & inhibitors
Chemical Substances	Biological Products ; Phorbols ; TRPV Cation Channels ; TRPV4 protein, human ; phorbol (XUZ76S9127)
Language	English
Publishing date	2020-02-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1063195-1
ISSN	1464-3405 ; 0960-894X
ISSN (online)	1464-3405
ISSN	0960-894X
DOI	10.1016/j.bmcl.2020.127022
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Zs.A 3203: Show issues

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Article ; Online: Relative Cross-Education Training Effects of Male Youth Exceed Male Adults.

Ben Othman, Ayem / Hadjizadeh Anvar, Saman / Aragão-Santos, José Carlos / Behm, David G / Chaouachi, Anis

Journal of strength and conditioning research

2024 Volume 38, Issue 5, Page(s) 881–890

Abstract: ... education training effects of male youth exceed male adults. J Strength Cond Res 38(5): 881-890, 2024-Cross ... Abstract: Ben Othman, A, Anvar, SH, Aragão-Santos, JC, Behm, DG, and Chaouachi, A. Relative cross ...

Abstract	Abstract: Ben Othman, A, Anvar, SH, Aragão-Santos, JC, Behm, DG, and Chaouachi, A. Relative cross-education training effects of male youth exceed male adults. J Strength Cond Res 38(5): 881-890, 2024-Cross-education has been studied extensively with adults, examining the training effects on contralateral homologous muscles. There is less information on the cross-education effects on contralateral heterologous muscles and scant information comparing these responses between adults and youth. The objective was to compare cross-education training effects in male youth and adults to contralateral homologous and heterologous muscles. Forty-two male children (10-13-years) and 42 adults (18-21-years) were tested before and following an 8-week unilateral, dominant or nondominant arm, chest press (CP) training program or control group (14 subjects each). Unilateral testing assessed dominant and nondominant limb strength with leg press and CP 1 repetition maximum (1RM), knee extensors, elbow extensors (EE), elbow flexors, and handgrip maximum voluntary isometric contraction (MVIC) strength and shot put distance and countermovement jump height. Upper-body tests demonstrated large magnitude increases, with children overall exceeding adults ( p = 0.05- p < 0.0001, η2 : 0.51, 10.4 ± 11.1%). The dominant trained limb showed significantly higher training adaptations than the nondominant limb for the adults with CP 1RM ( p = 0.03, η2 : 0.26, 6.7 ± 11.5%) and EE ( p = 0.008, η2 : 0.27, 8.8 ± 10.3%) MVIC force. Unilateral CP training induced significantly greater training adaptations with the ipsilateral vs. contralateral limb ( p = 0.008, η2 : 0.93, 27.8 ± 12.7%). In conclusion, children demonstrated greater training adaptations than adults, upper-body strength increased with no significant lower-body improvements, and ipsilateral training effects were greater than contralateral training in adults.
MeSH term(s)	Humans ; Male ; Adolescent ; Young Adult ; Muscle Strength/physiology ; Child ; Resistance Training/methods ; Muscle, Skeletal/physiology ; Isometric Contraction/physiology ; Hand Strength/physiology
Language	English
Publishing date	2024-01-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000004724
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Zs.A 6263: Show issues

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Article: Comment on: "Effects of Plyometric Training on Physical Performance: An Umbrella Review".

Ramirez-Campillo, Rodrigo / Afonso, José / Moran, Jason / Behm, David G / Granacher, Urs

Sports medicine - open

2023 Volume 9, Issue 1, Page(s) 73

Language	English
Publishing date	2023-08-14
Publishing country	Switzerland
Document type	Letter ; Comment
ZDB-ID	2809942-4
ISSN	2198-9761 ; 2199-1170
ISSN (online)	2198-9761
ISSN	2199-1170
DOI	10.1186/s40798-023-00595-3
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Article ; Online: The non-local effects of 7-week foot sole static stretching and foam rolling training on shoulder extension range of motion.

Konrad, Andreas / Reiner, Marina / Manieu, Josefina / Fischer, Josef / Schöpflin, Adrian / Tilp, Markus / Behm, David G

Frontiers in sports and active living

2024 Volume 5, Page(s) 1335872

Abstract: Static stretching and foam rolling can increase the range of motion (ROM) of a joint acutely as well as chronically. Although studies have reported ROM increases of a non-stretched heterologous muscle (non-local) following an acute static stretching or ... ...

Abstract	Static stretching and foam rolling can increase the range of motion (ROM) of a joint acutely as well as chronically. Although studies have reported ROM increases of a non-stretched heterologous muscle (non-local) following an acute static stretching or foam rolling session, these effects have not been studied for long-term training interventions. Therefore, the purpose of this study was to investigate the effects of a comprehensive 7-week static stretching and foam rolling training program of the foot sole on shoulder extension ROM. A total of 33 healthy, physically active participants (20 male) were assigned to either the intervention (
Language	English
Publishing date	2024-01-12
Publishing country	Switzerland
Document type	Journal Article
ISSN	2624-9367
ISSN (online)	2624-9367
DOI	10.3389/fspor.2023.1335872
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Article ; Online: Do Self-Myofascial Release Devices Release Myofascia? Rolling Mechanisms: A Narrative Review.

Behm, David G / Wilke, Jan

Sports medicine (Auckland, N.Z.)

2019 Volume 49, Issue 8, Page(s) 1173–1181

Abstract: The term "self-myofascial release" is ubiquitous in the rehabilitation and training literature and purports that the use of foam rollers and other similar devices release myofascial constrictions accumulated from scar tissue, ischaemia-induced muscle ... ...

Abstract	The term "self-myofascial release" is ubiquitous in the rehabilitation and training literature and purports that the use of foam rollers and other similar devices release myofascial constrictions accumulated from scar tissue, ischaemia-induced muscle spasms and other pathologies. Myofascial tone can be modulated with rollers by changes in thixotropic properties, blood flow, and fascial hydration affecting tissue stiffness. While rollers are commonly used as a treatment for myofascial trigger points, the identification of trigger points is reported to not be highly reliable. Rolling mechanisms underlying their effect on pain suppression are not well elucidated. Other rolling-induced mechanisms to increase range of motion or reduce pain include the activation of cutaneous and fascial mechanoreceptors and interstitial type III and IV afferents that modulate sympathetic/parasympathetic activation as well as the activation of global pain modulatory systems and reflex-induced reductions in muscle and myofascial tone. This review submits that there is insufficient evidence to support that the primary mechanisms underlying rolling and other similar devices are the release of myofascial restrictions and thus the term "self-myofascial release" devices is misleading.
MeSH term(s)	Humans ; Massage/instrumentation ; Muscle, Skeletal ; Pain ; Pain Management ; Range of Motion, Articular
Language	English
Publishing date	2019-06-29
Publishing country	New Zealand
Document type	Journal Article ; Review
ZDB-ID	605911-9
ISSN	1179-2035 ; 0112-1642
ISSN (online)	1179-2035
ISSN	0112-1642
DOI	10.1007/s40279-019-01149-y
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Zs.A 2010: Show issues

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Article: Effects of Chronic Static Stretching on Maximal Strength and Muscle Hypertrophy: A Systematic Review and Meta-Analysis with Meta-Regression.

Warneke, Konstantin / Lohmann, Lars Hubertus / Behm, David G / Wirth, Klaus / Keiner, Michael / Schiemann, Stephan / Wilke, Jan

Sports medicine - open

2024 Volume 10, Issue 1, Page(s) 45

Abstract: Background: Increases in maximal strength and muscle volume represent central aims of training interventions. Recent research suggested that the chronic application of stretch may be effective in inducing hypertrophy. The present systematic review ... ...

Abstract	Background: Increases in maximal strength and muscle volume represent central aims of training interventions. Recent research suggested that the chronic application of stretch may be effective in inducing hypertrophy. The present systematic review therefore aimed to syntheisize the evidence on changes of strength and muscle volume following chronic static stretching. Methods: Three data bases were sceened to conduct a systematic review with meta-analysis. Studies using randomized, controlled trials with longitudinal (≥ 2 weeks) design, investigating strength and muscle volume following static stretching in humans, were included. Study quality was rated by two examiners using the PEDro scale. Results: A total of 42 studies with 1318 cumulative participants were identified. Meta-analyses using robust variance estimation showed small stretch-mediated maximal strength increases (d = 0.30 p < 0.001) with stretching duration and intervention time as significant moderators. Including all studies, stretching induced small magnitude, but significant hypertrophy effects (d = 0.20). Longer stretching durations and intervention periods as well as higher training frequencies revealed small (d = 0.26-0.28), but significant effects (p < 0.001-0.005), while lower dosage did not reach the level of significance (p = 0.13-0.39). Conclusions: While of minor effectiveness, chronic static stretching represents a possible alternative to resistance training when aiming to improve strength and increase muscle size. As a dose-response relationship may exist, higher stretch durations and frequencies as well as long program durations should be further elaborated.
Language	English
Publishing date	2024-04-19
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2809942-4
ISSN	2198-9761 ; 2199-1170
ISSN (online)	2198-9761
ISSN	2199-1170
DOI	10.1186/s40798-024-00706-8
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