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  1. Article ; Online: Fibromyalgia and the Difficult Synthesis.

    Di Carlo, Marco / Bianchi, Benedetta / Salaffi, Fausto

    The Journal of rheumatology

    2024  

    Abstract: The pathophysiological uncertainties in fibromyalgia (FM) mean that its diagnosis, to this day, remains a strictly clinical exercise. The physician's evaluation of symptoms is therefore of fundamental importance both for the correct diagnostic framing of ...

    Abstract The pathophysiological uncertainties in fibromyalgia (FM) mean that its diagnosis, to this day, remains a strictly clinical exercise. The physician's evaluation of symptoms is therefore of fundamental importance both for the correct diagnostic framing of the patient and also for guiding a personalized therapeutic approach.
    Language English
    Publishing date 2024-04-15
    Publishing country Canada
    Document type Editorial
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.2024-0321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1168: Show issues Location:
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    Zs.MO 135: Show issues

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  2. Article: Is It Good to Simplify Clinimetry in Chronic Inflammatory Joint Diseases?

    Di Carlo, Marco / Salaffi, Fausto

    The Journal of rheumatology

    2022  Volume 49, Issue 10, Page(s) 1079–1081

    MeSH term(s) Humans ; Joint Diseases ; Chronic Disease
    Language English
    Publishing date 2022-07-01
    Publishing country Canada
    Document type Editorial ; Comment
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.220543
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    Zs.MO 135: Show issues

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  3. Article ; Online: Toning down the role of eosinophils in eosinophilic oesophagitis.

    Rossi, Carlo Maria / Lenti, Marco Vincenzo / Di Sabatino, Antonio

    Gut

    2024  Volume 73, Issue 5, Page(s) 874–875

    MeSH term(s) Humans ; Eosinophilic Esophagitis/diagnosis ; Eosinophils ; Esophagitis ; Enteritis ; Gastritis ; Eosinophilia
    Language English
    Publishing date 2024-04-05
    Publishing country England
    Document type Letter
    ZDB-ID 80128-8
    ISSN 1468-3288 ; 0017-5749
    ISSN (online) 1468-3288
    ISSN 0017-5749
    DOI 10.1136/gutjnl-2023-329864
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    Zs.A 160: Show issues Location:
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  4. Article ; Online: Central Sensitization in Psoriatic Arthritis: Relationship With Composite Measures of Disease Activity, Functional Disability, and Health-Related Quality of Life.

    Salaffi, Fausto / Farah, Sonia / Bianchi, Benedetta / Di Carlo, Marco

    The Journal of rheumatology

    2024  Volume 51, Issue 2, Page(s) 144–149

    Abstract: Objective: To investigate the prevalence of central sensitization (CS) in patients with psoriatic arthritis (PsA) and its association with disease activity and patient-reported outcome measures.: Methods: This cross-sectional study included adults ... ...

    Abstract Objective: To investigate the prevalence of central sensitization (CS) in patients with psoriatic arthritis (PsA) and its association with disease activity and patient-reported outcome measures.
    Methods: This cross-sectional study included adults with PsA without coexisting fibromyalgia (FM). Patients underwent a clinimetric assessment to collect variables regarding disease activity, quality of life (QOL), functional ability, impact of disease, and CS. Spearman ρ was used to examine the relationship between CS Inventory (CSI) scores and other variables. A multivariate analysis was performed to determine the independent contribution of each variable to the 12-item Psoriatic Arthritis Impact of Disease (PsAID-12) score.
    Results: One hundred fifty-seven patients were enrolled. Of them, 45.2% scored a CSI ≥ 40, indicating a high probability of CS. Significant correlations were found between CSI and disease activity, as evaluated by Disease Activity in Psoriatic Arthritis score and Psoriatic Arthritis Disease Activity Score (ρ 0.587 and ρ 0.573, respectively), between CSI and the Health Assessment Questionnaire (ρ 0.607), and between CSI and the 36-item Short Form Health Survey physical component summary and mental component summary scores (ρ -0.405 and ρ -0.483, respectively). In multivariate analysis, CSI score was the principal independent variable (
    Conclusion: Patients with PsA with symptoms of CS had higher disease activity, worse functional ability, and worse QOL. The presence of CS is the major contributor in the impact of disease.
    MeSH term(s) Adult ; Humans ; Arthritis, Psoriatic/diagnosis ; Quality of Life ; Central Nervous System Sensitization ; Cross-Sectional Studies ; Severity of Illness Index
    Language English
    Publishing date 2024-02-01
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.2023-0177
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  5. Article ; Online: Can Electroacupuncture Be Useful in Opioid-Induced Hyperalgesia? A Case Report.

    Di Carlo, Marco / D'Addario, Antonio / Salaffi, Fausto

    Journal of acupuncture and meridian studies

    2023  Volume 16, Issue 5, Page(s) 183–187

    Abstract: Opioid-induced hyperalgesia (OIH) is characterized by a paradoxical increase in pain sensitivity following opioid exposure. Although animal models indicate that electroacupuncture (EA) is effective against pain sensitization, there are no reports of its ... ...

    Abstract Opioid-induced hyperalgesia (OIH) is characterized by a paradoxical increase in pain sensitivity following opioid exposure. Although animal models indicate that electroacupuncture (EA) is effective against pain sensitization, there are no reports of its clinical application in OIH treatment. This case report involves an adult patient with osteomalacia complicated by multiple vertebral fragility fractures. The patient developed OIH following the use of oxycodone to treat severe disabling lower back pain that was refractory to nonsteroidal anti-inflammatory drugs. After hospitalization and treatment with low EA-frequency (2-10 Hz) sessions, the patient exhibited significant pain reduction and functional recovery after the first session, which was accompanied by steady progressive improvement as the treatment continued. This case report illustrates the clinical efficacy of EA in OIH treatment and indicates that EA, which has multiple modes of action on the neurobiology of chronic pain, has potential applications in the management of complex and difficult-to-manage conditions, such as OIH.
    MeSH term(s) Animals ; Humans ; Hyperalgesia/chemically induced ; Hyperalgesia/therapy ; Analgesics, Opioid/adverse effects ; Electroacupuncture ; Pain Threshold ; Chronic Pain/drug therapy
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2023-10-27
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2496980-1
    ISSN 2093-8152 ; 2093-8152
    ISSN (online) 2093-8152
    ISSN 2093-8152
    DOI 10.51507/j.jams.2023.16.5.183
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  6. Article: Kihon Checklist validation in patients with rheumatoid arthritis: Italian translation, cross-cultural adaptation, and evaluation of the validity in comparison to two frailty screening tools based on the Fried phenotype and deficit accumulation model.

    Salaffi, Fausto / Farah, Sonia / Di Carlo, Marco

    Clinical and experimental rheumatology

    2023  Volume 41, Issue 7, Page(s) 1528–1536

    Abstract: Objectives: To compare the diagnostic test accuracy in terms of discriminant validity of the Kihon Checklist (KCL), Italian version, with respect to the Comprehensive Rheumatologic Assessment of Frailty (CRAF), and the Survey of Health, Ageing and ... ...

    Abstract Objectives: To compare the diagnostic test accuracy in terms of discriminant validity of the Kihon Checklist (KCL), Italian version, with respect to the Comprehensive Rheumatologic Assessment of Frailty (CRAF), and the Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI) in identifying the presence of frailty in rheumatoid arthritis (RA) patients.
    Methods: An Italian version of the KCL was obtained by a consensus of experts. Then, adult RA patients underwent a cross-sectional evaluation inclusive of KCL, CRAF, and SHARE-FI. The performance of the tools was determined in terms of differences in areas under the receiver operating characteristic curves (AUC-ROCs) considering the Cardiovascular Health Study (CHS) criteria has external gold standard. For KCL, the optimal cut-point was determined at the Youden index.
    Results: The study included 219 RA patients. The three tools provided varying frailty prevalence percentages, from 16.0% (SHARE-FI) to 35.6% (CRAF). No scale performed better than others, according to AUC-ROCs comparisons, and when compared to the CHS criteria, all scales have an accuracy rate >80%. A KCL cut-off point of 7 resulted the optimum trade-off for sensitivity (93.3%), specificity (90.8%), with a positive likelihood ratio of 10.15.
    Conclusions: All the tools examined were useful and reflected the definition of frailty, however, the KCL was the most suitable since it is self-administered and might enable interventions in RA patients.
    MeSH term(s) Humans ; Frailty/diagnosis ; Frailty/epidemiology ; Checklist ; Cross-Sectional Studies ; Cross-Cultural Comparison ; Arthritis, Rheumatoid/diagnosis ; Italy ; Phenotype
    Language English
    Publishing date 2023-05-15
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
    DOI 10.55563/clinexprheumatol/r9ufbo
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  7. Article: Is Active Synovitis of Metacarpophalangeal Joints a Neuropathic Condition in Rheumatoid Arthritis Patients? Results from an Ultrasound Study of Palmar Digital Nerves.

    Di Carlo, Marco / Di Battista, Jacopo / Cipolletta, Edoardo / Okano, Tadashi / Chiorrini, Riccardo / Smerilli, Gianluca / Bandinelli, Francesca / Filippucci, Emilio / Salaffi, Fausto

    Journal of clinical medicine

    2024  Volume 13, Issue 6

    Abstract: 1) ...

    Abstract (1)
    Language English
    Publishing date 2024-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13061599
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  8. Article ; Online: Reproducibility of retinal vessel density among three different OCTA devices in ADOA patients.

    Lombardo, Marco / Di Marco, Ernesto / Nucci, Carlo / Cesareo, Massimo

    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie

    2022  Volume 261, Issue 1, Page(s) 277–279

    MeSH term(s) Humans ; Reproducibility of Results ; Retinal Vessels ; Fluorescein Angiography ; Tomography, Optical Coherence
    Language English
    Publishing date 2022-08-08
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 8435-9
    ISSN 1435-702X ; 0721-832X
    ISSN (online) 1435-702X
    ISSN 0721-832X
    DOI 10.1007/s00417-022-05788-2
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  9. Article ; Online: Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review.

    Covello, Carlo / Di Vincenzo, Federica / Cammarota, Giovanni / Pizzoferrato, Marco

    Current issues in molecular biology

    2024  Volume 46, Issue 3, Page(s) 2658–2677

    Abstract: Microplastics and nanoplastics (MNPs) are becoming an increasingly severe global problem due to their widespread distribution and complex impact on living organisms. Apart from their environmental impact, the effects of MNPs on living organisms have also ...

    Abstract Microplastics and nanoplastics (MNPs) are becoming an increasingly severe global problem due to their widespread distribution and complex impact on living organisms. Apart from their environmental impact, the effects of MNPs on living organisms have also continued to attract attention. The harmful impact of MNPs has been extensively documented in marine invertebrates and larger marine vertebrates like fish. However, the research on the toxicity of these particles on mammals is still limited, and their possible effects on humans are poorly understood. Considering that MNPs are commonly found in food or food packaging, humans are primarily exposed to them through ingestion. It would be valuable to investigate the potential harmful effects of these particles on gut health. This review focuses on recent research exploring the toxicological impacts of micro- and nanoplastics on the gut, as observed in human cell lines and mammalian models. Available data from various studies indicate that the accumulation of MNPs in mammalian models and human cells may result in adverse consequences, in terms of epithelial toxicity, immune toxicity, and the disruption of the gut microbiota. The paper also discusses the current research limitations and prospects in this field, aiming to provide a scientific basis and reference for further studies on the toxic mechanisms of micro- and nanoplastics.
    Language English
    Publishing date 2024-03-21
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2000024-8
    ISSN 1467-3045 ; 1467-3037
    ISSN (online) 1467-3045
    ISSN 1467-3037
    DOI 10.3390/cimb46030168
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  10. Article: Reply to Comment on: Development and validation of the SImple FIbromyalgia Screening questionnaire for improving the recognition of fibromyalgia in daily practice.

    Salaffi, Fausto / Di Carlo, Marco

    Clinical and experimental rheumatology

    2020  Volume 38, Issue 6, Page(s) 1274

    MeSH term(s) Fibromyalgia/diagnosis ; Fibromyalgia/therapy ; Humans ; Pain Measurement ; Surveys and Questionnaires
    Language English
    Publishing date 2020-11-22
    Publishing country Italy
    Document type Letter ; Comment
    ZDB-ID 605886-3
    ISSN 1593-098X ; 0392-856X
    ISSN (online) 1593-098X
    ISSN 0392-856X
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