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  1. Article: O/S

    Roll, Richard / Schwartz, Eduardo / Subrahmanyam, Avanidhar

    Journal of financial economics Vol. 96, No. 1 , p. 1-17

    the relative trading activity in options and stock

    2010  Volume 96, Issue 1, Page(s) 1–17

    Author's details Richard Roll; Eduardo Schwartz; Avanidhar Subrahmanyam
    Keywords Handelsvolumen der Börse ; Optionsgeschäft ; Aktienmarkt ; USA
    Language English
    Size graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam [u.a.] ; Jena
    Document type Article
    ZDB-ID 187118-3
    ISSN 0304-405X
    Database ECONomics Information System

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  2. Article ; Online: SELF IN THE PATH(O)S OF THE NEW ENLIGHTENMENT

    OLGA LOUCHAKOVA-SCHWARTZ

    Agathos: An International Review of the Humanities and Social Sciences, Vol III, Iss 1, Pp 7-

    TOWARDS A NEW CLINICAL THEORY

    2012  Volume 30

    Abstract: ... the awareness of today’s societal and cultural problems. The paper focuses to resolving this conflict. The idea ... of New Enlightenment comes out of Tymieniecka’s phenomenological analysis of the logoic networks of life ...

    Abstract Starting from the New Enlightenment, announced by Anna-Teresa Tymieniecka to be emerging in the post-postmodern era, a conflict is possible to manifest between the positive spirit in the name and the awareness of today’s societal and cultural problems. The paper focuses to resolving this conflict. The idea of New Enlightenment comes out of Tymieniecka’s phenomenological analysis of the logoic networks of life with identification of logoic unification of reason and intuition, and the insight into the ontological self-poiesis of life, i.e. ontopoiesis. Scientific progress takes place due to the ontopoietic self-disclosure of life. Understanding the ontopoiesis refocuses attention from trauma to the growing loci of the self, and creates an emergent alternative to existential pessimism of postmodern therapies. The paper examines healing aspects of ontopoietic direct intuition that mediate living engagement with the real. Human subject is not thrown into existence against the will, but is integrated into the flow of life and posesses selfreflective freedom of choice. This reframing of existential yearning invokes new clinical theory. The expanded interpretation of self and other, of health and disease calls for transformation of the mind towards the rise of ontopoietic intuition and direct perception of logoic ontopoiesis.
    Keywords Tymieniecka ; phenomenology ; self ; postmodernism ; clinical theory ; History of scholarship and learning. The humanities ; AZ20-999 ; Social sciences (General) ; H1-99
    Subject code 100
    Language German
    Publishing date 2012-05-01T00:00:00Z
    Publisher Alexandru Ioan Cuza University Press
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Transcription factor DREF regulates expression of the microRNA gene bantam in Drosophila melanogaster.

    Schwartz, M B / Prudnikova, M M / Andreenkov, O V / Volkova, E I / Zhimulev, I F / Antonenko, O V / Demakov, S A

    Vavilovskii zhurnal genetiki i selektsii

    2024  Volume 28, Issue 2, Page(s) 131–137

    Abstract: The bantam gene encodes a vital microRNA and has a complex expression pattern in various tissues at different stages of Drosophila development. This microRNA is involved in the control of normal development of the ocular and wing imaginal discs, the ... ...

    Abstract The bantam gene encodes a vital microRNA and has a complex expression pattern in various tissues at different stages of Drosophila development. This microRNA is involved in the control of normal development of the ocular and wing imaginal discs, the central nervous system, and also in maintaining the undifferentiated state of stem cells in the ovaries of adult females. At the cellular level, bantam stimulates cell proliferation and prevents apoptosis. The bantam gene is a target of several conserved signaling cascades, in particular, Hippo. At the moment, at least ten proteins are known to directly regulate the expression of this gene in different tissues of Drosophila. In this study, we found that the bantam regulatory region contains motifs characteristic of binding sites for DREF, a transcription factor that regulates the expression of Hippo cascade genes. Using transgenic lines containing a full-length bantam lethality-rescuing deletion fragment and a fragment with a disrupted DREF binding site, we show that these motifs are functionally significant because their disruption at the bantam locus reduces expression levels in the larvae and ovaries of homozygous flies, which correlates with reduced vitality and fertility. The effect of DREF binding to the promoter region of the bantam gene on its expression level suggests an additional level of complexity in the regulation of expression of this microRNA. A decrease in the number of eggs laid and a shortening of the reproductive period in females when the DREF binding site in the regulatory region of the bantam gene is disrupted suggests that, through bantam, DREF is also involved in the regulation of Drosophila oogenesis.
    Language English
    Publishing date 2024-04-27
    Publishing country Russia (Federation)
    Document type Journal Article
    ISSN 2500-0462
    ISSN 2500-0462
    DOI 10.18699/vjgb-24-20
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Exposure to Secreted Bacterial Factors Promotes HIV-1 Replication in CD4

    Znaidia, M / de Souza-Angelo, Y / Létoffé, S / Staropoli, I / Grzelak, L / Ghigo, J M / Schwartz, O / Casartelli, N

    Microbiology spectrum

    2023  Volume 11, Issue 2, Page(s) e0431322

    Abstract: Microbial translocation is associated with systemic immune activation in HIV-1 disease. Circulating T cells can encounter microbial products in the bloodstream and lymph nodes, where viral replication takes place. The mechanisms by which bacteria ... ...

    Abstract Microbial translocation is associated with systemic immune activation in HIV-1 disease. Circulating T cells can encounter microbial products in the bloodstream and lymph nodes, where viral replication takes place. The mechanisms by which bacteria contribute to HIV-associated pathogenesis are not completely deciphered. Here, we examined how bacteria may impact T cell function and viral replication. We established cocultures between a panel of live bacteria and uninfected or HIV-1-infected activated peripheral blood CD4-positive (CD4
    MeSH term(s) Humans ; HIV-1/physiology ; HIV Infections ; Bacteria ; CD4-Positive T-Lymphocytes ; Virus Replication
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.04313-22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The text-package: An R-package for analyzing and visualizing human language using natural language processing and transformers.

    Kjell, Oscar / Giorgi, Salvatore / Schwartz, H Andrew

    Psychological methods

    2023  Volume 28, Issue 6, Page(s) 1478–1498

    Abstract: The language that individuals use for expressing themselves contains rich psychological information. Recent significant advances in Natural Language Processing (NLP) and Deep Learning (DL), namely transformers, have resulted in large performance gains in ...

    Abstract The language that individuals use for expressing themselves contains rich psychological information. Recent significant advances in Natural Language Processing (NLP) and Deep Learning (DL), namely transformers, have resulted in large performance gains in tasks related to understanding natural language. However, these state-of-the-art methods have not yet been made easily accessible for psychology researchers, nor designed to be optimal for human-level analyses. This tutorial introduces text (https://r-text.org/), a new R-package for analyzing and visualizing human language using transformers, the latest techniques from NLP and DL. The text-package is both a modular solution for accessing state-of-the-art language models and an end-to-end solution catered for human-level analyses. Hence, text provides user-friendly functions tailored to test hypotheses in social sciences for both relatively small and large data sets. The tutorial describes methods for analyzing text, providing functions with reliable defaults that can be used off-the-shelf as well as providing a framework for the advanced users to build on for novel pipelines. The reader learns about three core methods: (1) textEmbed(): to transform text to modern transformer-based word embeddings; (2) textTrain() and textPredict(): to train predictive models with embeddings as input, and use the models to predict from; (3) textSimilarity() and textDistance(): to compute semantic similarity/distance scores between texts. The reader also learns about two extended methods: (1) textProjection()/textProjectionPlot() and (2) textCentrality()/textCentralityPlot(): to examine and visualize text within the embedding space. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
    MeSH term(s) Humans ; Natural Language Processing ; Language ; Semantics ; Social Sciences
    Language English
    Publishing date 2023-05-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2103345-6
    ISSN 1939-1463 ; 1082-989X
    ISSN (online) 1939-1463
    ISSN 1082-989X
    DOI 10.1037/met0000542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Precocious puberty and Chiari I malformation with syrinx: a case report of an unusual presentation of Costello syndrome.

    Schwartz, Naomi S / Regelmann, Molly O

    International journal of pediatric endocrinology

    2019  Volume 2019, Page(s) 2

    Abstract: Background: Costello syndrome (CS) is a rare RASopathy causing developmental delays, short stature and classically, delayed puberty. We present a patient with CS and central precocious puberty (CPP).: Case presentation: A female patient with CS ... ...

    Abstract Background: Costello syndrome (CS) is a rare RASopathy causing developmental delays, short stature and classically, delayed puberty. We present a patient with CS and central precocious puberty (CPP).
    Case presentation: A female patient with CS presented at 6 years 10 months of age with breast development. CPP was biochemically confirmed at 7 years 1 month of age, no additional pituitary dysfunction was noted and puberty progressed at follow-up. Brain magnetic resonance imaging (MRI) revealed a Chiari I malformation with a syrinx, requiring surgical decompression. The patient was successfully treated with histrelin.
    Conclusions: Although recent publications do not recommend routine brain MRI in girls with isolated CPP over 6 years of age, in those with CS actionable MRI findings are more likely and imaging should be performed. It is unclear whether the cerebral malformation in the patient contributed to CPP or was an incidental syndromic finding.
    Language English
    Publishing date 2019-10-22
    Publishing country England
    Document type Case Reports
    ZDB-ID 2528691-2
    ISSN 1687-9856 ; 1687-9848
    ISSN (online) 1687-9856
    ISSN 1687-9848
    DOI 10.1186/s13633-019-0067-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Cognitive behavioral and mindfulness with daily exercise intervention is associated with changes in intestinal microbial taxa and systemic inflammation in patients with Crohn's disease.

    K, Ilan / Y, Motro / A, Nemirovsky / D, Schwartz / G, Goren / R, Sergienko / D, Greenberg / V, Slonim-Nevo / O, Sarid / M, Friger / S, Regev / S, Odes / J, Moran-Gilad / A, Monsonego

    Gut microbes

    2024  Volume 16, Issue 1, Page(s) 2337269

    Abstract: Crohn's disease (CD) is a chronic inflammatory bowel disease associated with psychological distress and intestinal microbial changes. Here, we examined whether a 3-month period of Cognitive Behavioral and Mindfulness with Daily Exercise (COBMINDEX) ... ...

    Abstract Crohn's disease (CD) is a chronic inflammatory bowel disease associated with psychological distress and intestinal microbial changes. Here, we examined whether a 3-month period of Cognitive Behavioral and Mindfulness with Daily Exercise (COBMINDEX) intervention, which improves the wellbeing and inflammatory state of CD patients, may also affect their gut microbiome. Gut microbiota, circulating inflammatory markers and hormones were analyzed in 24 CD patients before (T1) and after 3 months of COBMINDEX (T2), and in 25 age- and sex-matched wait-list control patients at the corresponding time-points. Microbiota analysis examined relative taxonomical abundance, alpha and beta diversity, and microbiome correlations with inflammatory and psychological parameters. At T1, CD patients exhibited a characteristic microbial profile mainly constituted of Proteobacteria (17.71%), Firmicutes (65.56%), Actinobacteria (8.46%) and Bacteroidetes (6.24%). Baseline bacterial abundances showed significant correlations with psychological markers of distress and with IFN
    MeSH term(s) Humans ; Crohn Disease/microbiology ; Mindfulness ; Gastrointestinal Microbiome ; Inflammation ; Exercise Therapy ; Cognition
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2575755-6
    ISSN 1949-0984 ; 1949-0984
    ISSN (online) 1949-0984
    ISSN 1949-0984
    DOI 10.1080/19490976.2024.2337269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: High negative predictive value of RT-PCR in patients with high likelihood of SARS-CoV-2 infection.

    Galmiche, S / Fernandes-Pellerin, S / Ungeheuer, M N / Schwartz, O / Attia, M / Hoen, B

    Infectious diseases now

    2021  Volume 52, Issue 1, Page(s) 52–53

    MeSH term(s) COVID-19 ; Humans ; Predictive Value of Tests ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2 ; Sensitivity and Specificity
    Language English
    Publishing date 2021-11-24
    Publishing country France
    Document type Letter
    ISSN 2666-9919
    ISSN (online) 2666-9919
    DOI 10.1016/j.idnow.2021.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Challenging the Classical View: Recognition of Identity and Expression as Integrated Processes.

    Schwartz, Emily / O'Nell, Kathryn / Saxe, Rebecca / Anzellotti, Stefano

    Brain sciences

    2023  Volume 13, Issue 2

    Abstract: Recent neuroimaging evidence challenges the classical view that face identity and facial expression are processed by segregated neural pathways, showing that information about identity and expression are encoded within common brain regions. This article ... ...

    Abstract Recent neuroimaging evidence challenges the classical view that face identity and facial expression are processed by segregated neural pathways, showing that information about identity and expression are encoded within common brain regions. This article tests the hypothesis that integrated representations of identity and expression arise spontaneously within deep neural networks. A subset of the CelebA dataset is used to train a deep convolutional neural network (DCNN) to label face identity (chance = 0.06%, accuracy = 26.5%), and the FER2013 dataset is used to train a DCNN to label facial expression (chance = 14.2%, accuracy = 63.5%). The identity-trained and expression-trained networks each successfully transfer to labeling both face identity and facial expression on the Karolinska Directed Emotional Faces dataset. This study demonstrates that DCNNs trained to recognize face identity and DCNNs trained to recognize facial expression spontaneously develop representations of facial expression and face identity, respectively. Furthermore, a congruence coefficient analysis reveals that features distinguishing between identities and features distinguishing between expressions become increasingly orthogonal from layer to layer, suggesting that deep neural networks disentangle representational subspaces corresponding to different sources.
    Language English
    Publishing date 2023-02-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13020296
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Can CO₂ sequestration in basalt efficiently reduce greenhouse gas emission?

    Schwartz, Michael O.

    Environmental technology. 2022 Mar. 21, v. 43, no. 7

    2022  

    Abstract: ... allows injection at a rate in the range of 9–19 kg CO₂/s, depending on permeability (4 × 10⁻¹⁴–10⁻¹³ m² ... operating at maximum capacity (19 kg CO₂/s) represents 50 TWh generated in a gas power station minus ...

    Abstract The research on the Columbia River Basalt is a unique combination of projects that minimise CO₂ emissions to the atmosphere. Both are underground waste disposal projects: CO₂ waste versus nuclear waste. The recent Wallula CO₂ project and the previous nuclear-waste project in the Columbia River Basalt (CRB), USA, provide the database for a high-capacity CO₂ sequestration model. Due to geomechanical constraints, the injection rate of CO₂ sequestration must be limited in order not to jeopardise the integrity of the reservoir and cap rock. The interbed in the continental flood basalt tested in the Wallula project only allows injection at a rate in the range of 9–19 kg CO₂/s, depending on permeability (4 × 10⁻¹⁴–10⁻¹³ m²) and porosity (0.1–0.15). At the end of a 50-year injection period, the fraction of CO₂ converted to carbonate minerals is 37.1–67.1%. Underground space for waste disposal is a rare asset. The Columbia River Basalt occupies an area of 200,000 km². Fifty years of CO₂ sequestration from a single well would require about the same fraction of the area as that of a nuclear waste repository (0.025%). The repository design is for a capacity of 70,000 MTHM (metric tons heavy metal). If all the waste is spent nuclear fuel, it originates from 1.2 × 10⁴–8.4 × 10⁴ TWh electric power production, depending on reactor type. The CO₂ injection well operating at maximum capacity (19 kg CO₂/s) represents 50 TWh generated in a gas power station minus the energy consumed for CO₂ separation, i.e. less than 0.4% of the nuclear option.
    Keywords assets ; basalt ; carbon dioxide ; databases ; electric power ; energy ; environmental technology ; greenhouse gas emissions ; heavy metals ; models ; nuclear fuels ; permeability ; porosity ; power generation ; power plants ; radioactive waste ; waste disposal ; Columbia River
    Language English
    Dates of publication 2022-0321
    Size p. 1082-1092.
    Publishing place Taylor & Francis
    Document type Article
    ISSN 1479-487X
    DOI 10.1080/09593330.2020.1815859
    Database NAL-Catalogue (AGRICOLA)

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