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  1. Article: Einfluss von Schüben auf die MS-Progression. Interview mit Prof. Dr. Peter Rieckmann

    Rieckmann, Peter

    Der Neurologe & Psychiater

    2010  Volume 11, Issue 2, Page(s) 14

    Language German
    Document type Article
    ZDB-ID 2036795-8
    ISSN 1616-2455
    Database Current Contents Medicine

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  2. Article: Cochrane-Metaanalyse zur Wirksamkeit von MS-Therapien. Was nützt MS-Patienten am meisten? Nachgefragt bei Professor Peter Rieckmann, Chefarzt Neurologische Klinik, Sozialstiftung Bamberg, Klinik am Bruderwald

    Rieckmann, Peter

    InFo Neurologie & Psychiatrie

    2013  Volume 15, Issue 9, Page(s) 8

    Language German
    Document type Article
    ZDB-ID 2008542-4
    ISSN 1437-062X
    Database Current Contents Medicine

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  3. Article: The Association Between Actigraphy-Derived Behavioral Clusters and Self-Reported Fatigue in Persons With Multiple Sclerosis: Cross-sectional Study.

    Gulde, Philipp / Rieckmann, Peter

    JMIR rehabilitation and assistive technologies

    2022  Volume 9, Issue 1, Page(s) e31164

    Abstract: Background: Persons with multiple sclerosis frequently report increased levels of fatigue and fatigability. However, behavioral surrogates that are strongly associated with self-reports are lacking, which limits research and treatment.: Objective: ... ...

    Abstract Background: Persons with multiple sclerosis frequently report increased levels of fatigue and fatigability. However, behavioral surrogates that are strongly associated with self-reports are lacking, which limits research and treatment.
    Objective: The aim of this study was to derive distinct behavioral syndromes that are reflected by self-reports concerning fatigue and fatigability.
    Methods: We collected actigraphic data of 30 persons with multiple sclerosis over a period of 1 week during an inpatient stay at a neurorehabilitation facility. Further, participants completed the German fatigue severity scale. A principal component analysis of actigraphic parameters was performed to extract the latent component levels of behaviors that reflect fatigue (quantity of activity) and fatigability (fragmentation of activity). The resulting components were used in a cluster analysis.
    Results: Analyses suggested 3 clusters, one with high activity (d=0.65-1.57) and low clinical disability levels (d=0.91-1.39), one with high levels of sedentary behavior (d=1.06-1.58), and one with strong activity fragmentation (d=1.39-1.94). The cluster with high levels of sedentary behavior further revealed strong differences from the other clusters concerning participants' reported levels of fatigue (d=0.99-1.28).
    Conclusions: Cluster analysis data proved to be feasible to meaningfully differentiate between different behavioral syndromes. Self-reports reflected the different behavioral syndromes strongly. Testing of additional domains (eg, volition or processing speed) and assessments during everyday life seem warranted to better understand the origins of reported fatigue symptomatology.
    Language English
    Publishing date 2022-03-17
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2798120-4
    ISSN 2369-2529
    ISSN 2369-2529
    DOI 10.2196/31164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Going beyond PA: Assessing sensorimotor capacity with wearables in multiple sclerosis-a cross-sectional study.

    Gulde, Philipp / Vojta, Heike / Schmidle, Stephanie / Rieckmann, Peter / Hermsdörfer, Joachim

    Journal of neuroengineering and rehabilitation

    2023  Volume 20, Issue 1, Page(s) 123

    Abstract: Background: Wearable technologies are currently clinically used to assess energy expenditure in a variety of populations, e.g., persons with multiple sclerosis or frail elderly. To date, going beyond physical activity, deriving sensorimotor capacity ... ...

    Abstract Background: Wearable technologies are currently clinically used to assess energy expenditure in a variety of populations, e.g., persons with multiple sclerosis or frail elderly. To date, going beyond physical activity, deriving sensorimotor capacity instead of energy expenditure, is still lacking proof of feasibility.
    Methods: In this study, we read out sensors (accelerometer and gyroscope) of smartwatches in a sample of 90 persons with multiple sclerosis over the course of one day of everyday life in an inpatient setting. We derived a variety of different kinematic parameters, in addition to lab-based tests of sensorimotor performance, to examine their interrelation by principal component, cluster, and regression analyses.
    Results: These analyses revealed three components of behavior and sensorimotor capacity, namely clinical characteristics with an emphasis on gait, gait-related physical activity, and upper-limb related physical activity. Further, we were able to derive four clusters with different behavioral/capacity patterns in these dimensions. In a last step, regression analyses revealed that three selected smartwatch derived kinematic parameters were able to partially predict sensorimotor capacity, e.g., grip strength and upper-limb tapping.
    Conclusions: Our analyses revealed that physical activity can significantly differ between persons with comparable clinical characteristics and that assessments of physical activity solely relying on gait can be misleading. Further, we were able to extract parameters that partially go beyond physical activity, with the potential to be used to monitor the course of disease progression and rehabilitation, or to early identify persons at risk or a sub-clinical threshold of disease severity.
    MeSH term(s) Aged ; Humans ; Cross-Sectional Studies ; Multiple Sclerosis/diagnosis ; Energy Metabolism ; Exercise ; Wearable Electronic Devices
    Language English
    Publishing date 2023-09-21
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2164377-5
    ISSN 1743-0003 ; 1743-0003
    ISSN (online) 1743-0003
    ISSN 1743-0003
    DOI 10.1186/s12984-023-01247-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Outside the Laboratory Assessment of Upper Limb Laterality in Patients With Stroke: A Cross-Sectional Study.

    Gulde, Philipp / Vojta, Heike / Schmidle, Stephanie / Rieckmann, Peter / Hermsdörfer, Joachim

    Stroke

    2023  Volume 55, Issue 1, Page(s) 146–155

    Abstract: Background: The rehabilitation of upper limb sensorimotor performance after stroke requires the assessment of daily use, the identification of key levels of impairment, and monitoring the course of recovery. It needs to be answered, how laboratory-based ...

    Abstract Background: The rehabilitation of upper limb sensorimotor performance after stroke requires the assessment of daily use, the identification of key levels of impairment, and monitoring the course of recovery. It needs to be answered, how laboratory-based assessments and everyday behavior are connected, which dimension of metrics, that is, volume, intensity, or quality, is most sensitive to reduced function, and what sensor, that is, gyroscope or accelerometer, is best suited to gather such data.
    Methods: Performance in laboratory-based sensorimotor tests, as well as smartwatch-derived kinematic data of everyday life relative upper limb activity, during 1 day of inpatient neurorehabilitation (Germany, 2022) of 50 patients with stroke, was cross-sectionally assessed and resulting laterality indices (performance ratios) between the limbs were analyzed using ANCOVAs and principal component analysis.
    Results: Laboratory-based tests revealed the strongest laterality indices, followed by smartwatch-based (intensity>quality>volume) metrics. Angular velocity-based metrics revealed higher laterality indices than acceleration-based ones. Laterality indices were overall well associated; however, a principal component analysis suggested upper limb impairments to be unidimensional.
    Conclusions: Our findings suggest that the use of sensors can deliver valid information of stroke-related laterality. It appeared that commonly used metrics that estimate the volume of use (ie, energy expenditure) are not the most sensitive. Especially reached intensities could be well used for monitoring, because they are more dependent on the performance of the sensorimotor system and less on confounders like age. The unidimensionality of the upper limb laterality suggests that an impaired limb with reduced movement quality and the inability to reach higher intensities will be used less in everyday life, especially when it is the nondominant side.
    MeSH term(s) Humans ; Cross-Sectional Studies ; Stroke Rehabilitation/methods ; Stroke/diagnosis ; Upper Extremity ; Activities of Daily Living ; Recovery of Function
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.123.043657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Changes in thumb tapping rates and central motor conduction times are associated in persons with multiple sclerosis.

    Gulde, Philipp / Cetin, Mehmet / Hermsdörfer, Joachim / Rieckmann, Peter

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2022  Volume 43, Issue 8, Page(s) 4945–4951

    Abstract: Introduction: In persons with multiple sclerosis, nerve conductivity can be reduced. The assessment is generally performed via motor evoked potentials (MEP). So far, a strongly associated motor performance surrogate for changes in the extracted central ... ...

    Abstract Introduction: In persons with multiple sclerosis, nerve conductivity can be reduced. The assessment is generally performed via motor evoked potentials (MEP). So far, a strongly associated motor performance surrogate for changes in the extracted central motor conduction time (CMCT) is missing.
    Methods: CMCT and performance in the nine-hole peg test and maximum thumb tapping frequencies over 10 s of 12 persons with multiple sclerosis were measured prior to and after training over 5 consecutive days. Each training consisted of 10,000 thumb taps at maximum effort with the dominant upper limb.
    Results: The dominant upper limb improved in maximum tapping frequency over 10 s (d = 0.79) and 10,000 taps (d = 1.04), the nine-hole peg test (d = 0.60), and CMCT (d = 0.52). The nondominant upper limb only improved in the nine-hole peg test (d = 0.38). Models of multiple linear regression predicted 0.78 (model 1, tapping performance as factors) and 0.87 (model 2, patient baseline characteristics as factors) of the variance in CMCT changes.
    Discussion: Changes in CMCT were well predictable, although the assessment of those surrogates is either not economic (model 1) or rather describing a potential of change (model 2). However, we were able to show moderate changes in CMCT within 5 days.
    MeSH term(s) Evoked Potentials, Motor/physiology ; Humans ; Multiple Sclerosis/diagnosis ; Neural Conduction/physiology ; Thumb ; Transcranial Magnetic Stimulation
    Language English
    Publishing date 2022-04-04
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-05991-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Professionelle Begleitung durch geschultes Pflege- und Praxispersonal : Frei und selbstbestimmt leben mit Multipler Sklerose

    Rieckmann, Peter

    Heilberufe

    2017  Volume 69, Issue 9, Page(s) 36–37

    Keywords Selbstbestimmung
    Language German
    Document type Article
    Note Nicht online
    ZDB-ID 541233-x
    ISSN 1867-1535 ; 0017-9604
    ISSN (online) 1867-1535
    ISSN 0017-9604
    Database bibnet.org

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  8. Article: Inpatient Rehabilitation: Prediction of Changes in Sensorimotor Performance in Multiple Sclerosis: A Pilot Study.

    Gulde, Philipp / Hermsdörfer, Joachim / Rieckmann, Peter

    Journal of clinical medicine

    2021  Volume 10, Issue 10

    Abstract: Inpatient rehabilitation has been shown to be an effective intervention for sensorimotor performance in multiple sclerosis (MS) patients. So far, predictions of the rehabilitation outcomes are limited. The objective was to predict inpatient ... ...

    Abstract Inpatient rehabilitation has been shown to be an effective intervention for sensorimotor performance in multiple sclerosis (MS) patients. So far, predictions of the rehabilitation outcomes are limited. The objective was to predict inpatient rehabilitation outcomes by changes in the Watzmann Severity Scale (WSS), a statistical estimation of the EDSS by sensorimotor capacity. Sensorimotor performance and physical activity during rehabilitation (by actigraphy) were assessed in a sample of 28 MS patients at a facility for neurorehabilitation. Daily changes in the WSS were predicted by a model of multiple linear regression. The resulting model had an R
    Language English
    Publishing date 2021-05-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10102177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Speed but Not Smoothness of Gait Reacts to Rehabilitation in Multiple Sclerosis.

    Gulde, Philipp / Hermsdörfer, Joachim / Rieckmann, Peter

    Multiple sclerosis international

    2021  Volume 2021, Page(s) 5589562

    Abstract: Introduction: Improved gait is one of the leading therapy goals in multiple sclerosis. A plethora of clinical timed trials and state-of-the-art technology-based approaches are available to assess gait performance.: Objectives: To examine what aspects ...

    Abstract Introduction: Improved gait is one of the leading therapy goals in multiple sclerosis. A plethora of clinical timed trials and state-of-the-art technology-based approaches are available to assess gait performance.
    Objectives: To examine what aspects of gait react to inpatient rehabilitation in MS and which parameters should be best assessed.
    Design: In this longitudinal study, we examined the performance of 76 patients with MS to shed further light on factors influencing gait, associations between tests, and the reaction to inpatient rehabilitation during an average time span of 16 d.
    Results: All gait parameters were strongly intercorrelated (all
    Conclusions: Since we were not able to observe improvements in smoothness of gait, we conclude that rehabilitation programs should be adapted to the patient's physiological capacities in order to allow for such improvements in smoothness of gait. Externally valid gait capacity (6MWT) could be predicted by a single walk for 10 s at natural pace.
    Language English
    Publishing date 2021-06-03
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2603577-7
    ISSN 2090-2662 ; 2090-2654
    ISSN (online) 2090-2662
    ISSN 2090-2654
    DOI 10.1155/2021/5589562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Sensorimotor function does not predict quality of life in persons with multiple sclerosis.

    Gulde, Philipp / Hermsdörfer, Joachim / Rieckmann, Peter

    Multiple sclerosis and related disorders

    2021  Volume 52, Page(s) 102986

    Abstract: Quality of life (QOL) has been reported to be reduced in persons with multiple sclerosis. Further, associations between QOL and the clinical severity of the disease as well as sensorimotor function were shown. We reinvestigated impacting factors on QOL ... ...

    Abstract Quality of life (QOL) has been reported to be reduced in persons with multiple sclerosis. Further, associations between QOL and the clinical severity of the disease as well as sensorimotor function were shown. We reinvestigated impacting factors on QOL by the additional assessment of depression, fatigue, satisfaction with life, and a battery of end-effector based assessments of sensorimotor functioning. Models of multiple linear regression revealed everyday life activity limitations to be the driving factor within the used questionnaire and no association with sensorimotor tests, but depression, fatigue, and satisfaction with life. We conclude that either psycho-emotional coping and adaptability are the dominant determinant of QOL or that QOL is in need of a quantitative and objective reconceptualization.
    MeSH term(s) Depression ; Fatigue ; Humans ; Multiple Sclerosis ; Quality of Life ; Surveys and Questionnaires
    Language English
    Publishing date 2021-04-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2645330-7
    ISSN 2211-0356 ; 2211-0348
    ISSN (online) 2211-0356
    ISSN 2211-0348
    DOI 10.1016/j.msard.2021.102986
    Database MEDical Literature Analysis and Retrieval System OnLINE

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