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Article: Factitiously Elevated Total Triiodothyronine in a Euthyroid Patient with Multiple Myeloma.

Mandal, Kaushik / Ashorobi, Damilola / Lee, Alice / Liao, Huijuan / Kumar, Salini C / Rosenthal, David S

Case reports in endocrinology

2021  Volume 2021, Page(s) 8479193

Abstract: Sporadic reports of factitious elevations of thyroid hormones related to laboratory interference from autoantibodies and multiple myeloma paraproteins have appeared in the literature. Such clinically confusing laboratory results can lead to erroneous ... ...

Abstract Sporadic reports of factitious elevations of thyroid hormones related to laboratory interference from autoantibodies and multiple myeloma paraproteins have appeared in the literature. Such clinically confusing laboratory results can lead to erroneous diagnoses and inappropriate treatments. We report an additional case of a patient with multiple myeloma and an IgG paraproteinemia who had such a spurious elevation of total T3 complicating her levothyroxine management of hypothyroidism. In addition, we alert clinicians that differences in performance characteristics between various manufacturers' test platforms may also cause spurious reports.
Language English
Publishing date 2021-08-30
Publishing country United States
Document type Case Reports
ZDB-ID 2627633-1
ISSN 2090-651X ; 2090-6501
ISSN (online) 2090-651X
ISSN 2090-6501
DOI 10.1155/2021/8479193
Database MEDical Literature Analysis and Retrieval System OnLINE

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