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  1. Article ; Online: An m-Health telerehabilitation and health education program on physical performance in patients with hip fracture and their family caregivers: Study protocol for the ActiveHip+ randomized controlled trial.

    Mora-Traverso, Marta / Molina-Garcia, Pablo / Prieto-Moreno, Rafael / Borges-Cosic, Milkana / Cruz Guisado, Victor / Del Pino Algarrada, Rogelio / Moreno-Ramírez, Paz / Gomez-Jurado, Gema / Gomez Tarrias, Consuelo / Hidalgo Isla, Margarita / Jimenez Andrés, Patricia / Linares Gago, Marta / Lirola-Liebanas, Ana / Mesa-Ruiz, Antonio / Muñoz-Garach, Araceli / Salazar-Graván, Susana / Estevez-Lopez, Fernando / Martín-Matillas, Miguel / Ariza-Vega, Patrocinio

    Research in nursing & health

    2022  Volume 45, Issue 3, Page(s) 287–299

    Abstract: ... multicentre randomized controlled trial (RCT) aims to test the effect of the ActiveHip+ m-Health system ... of a multidisciplinary m-Health system in the rehabilitation of patients with hip fracture. ...

    Abstract Telerehabilitation interventions administered via a smartphone may provide new feasible and effective rehabilitation options at home for patients with hip fracture. However, to date, no such interventions have been shown to be effective in the recovery key health outcomes of these patients. The present multicentre randomized controlled trial (RCT) aims to test the effect of the ActiveHip+ m-Health system in the recovery of physical performance, functional level, quality of life, and other health-related outcomes in both patients with hip fracture and their family caregivers. A total of 104 patients older than 65 years, with hip fracture, and their family caregivers will be randomized into the ActiveHip+ rehabilitation (N = 52) or the control group (N = 52). ActiveHip+ is a 12-week smartphone-based rehabilitation program conducted in Granada and Cádiz (Spain) that includes: (1) 24 sessions of physical exercise and 12 sessions of occupational therapy; (2) seven educational modules for patients and for caregivers; and (3) general recommendations in activities of daily living. The control group will receive the usual rehabilitation protocol offered by the Andalusian Public Healthcare System. The primary outcome is the patient's physical performance, while the secondary outcomes are the patient's functional level, quality of life, pain, fear of falling, fitness perception, pre-fracture functional level, emotional status, and caregiver burden. The present project will substantially contribute to the existing knowledge by testing for the first time the efficacy and feasibility of a multidisciplinary m-Health system in the rehabilitation of patients with hip fracture.
    MeSH term(s) Caregivers ; Health Education ; Hip Fractures/rehabilitation ; Humans ; Physical Functional Performance ; Quality of Life ; Randomized Controlled Trials as Topic ; Telerehabilitation/methods
    Language English
    Publishing date 2022-02-11
    Publishing country United States
    Document type Clinical Trial Protocol ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 424453-9
    ISSN 1098-240X ; 0160-6891
    ISSN (online) 1098-240X
    ISSN 0160-6891
    DOI 10.1002/nur.22218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neural crest derived progenitor cells contribute to tumor stroma and aggressiveness in stage 4/M neuroblastoma.

    Linares-Clemente, Pedro / Aguilar-Morante, Diana / Rodríguez-Prieto, Ismael / Ramírez, Gema / de Torres, Carmen / Santamaría, Vicente / Pascual-Vaca, Diego / Colmenero-Repiso, Ana / Vega, Francisco M / Mora, Jaume / Cabello, Rosa / Márquez, Catalina / Rivas, Eloy / Pardal, Ricardo

    Oncotarget

    2017  Volume 8, Issue 52, Page(s) 89775–89792

    Abstract: ... of gene expression profiles in stage 4/M NB revealed a neural crest stem cell (NCSC) gene signature that was associated ... in prognosis to improve stratification of stage 4/M NB tumors. Our results might facilitate the design of new ...

    Abstract Pediatric tumors arise upon oncogenic transformation of stem/progenitor cells during embryonic development. Given this scenario, the existence of non-tumorigenic stem cells included within the aberrant tumoral niche, with a potential role in tumor biology, is an intriguing and unstudied possibility. Here, we describe the presence and function of non-tumorigenic neural crest-derived progenitor cells in aggressive neuroblastoma (NB) tumors. These cells differentiate into neural crest typical mesectodermal derivatives, giving rise to tumor stroma and promoting proliferation and tumor aggressiveness. Furthermore, an analysis of gene expression profiles in stage 4/M NB revealed a neural crest stem cell (NCSC) gene signature that was associated to stromal phenotype and high probability of relapse. Thus, this NCSC gene expression signature could be used in prognosis to improve stratification of stage 4/M NB tumors. Our results might facilitate the design of new therapies by targeting NCSCs and their contribution to tumor stroma.
    Language English
    Publishing date 2017-10-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2560162-3
    ISSN 1949-2553 ; 1949-2553
    ISSN (online) 1949-2553
    ISSN 1949-2553
    DOI 10.18632/oncotarget.21128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Actividad antioxidante y antinflamatoria in vitro de extractos de chaya (Cnidoscolus aconitifolius (Mill.) I.M. Johnst).

    Us Medina, Ulil / Millán Linares, Maria Del Carmen / Arana Argáez, Victor / Segura-Campos, Maira Rubi

    Nutricion hospitalaria

    2019  Volume 37, Issue 1, Page(s) 46–55

    Abstract: Introduction: Introduction: noncommunicable diseases (NCDs) are the main cause of death worldwide. Secondary metabolites from plant sources such as Cnidoscolus aconitifolius may be used as adjuvants in the prevention of diseases related to oxidative ... ...

    Title translation In vitro antioxidant and anti-inflammatory activity of chaya extracts (Cnidoscolus aconitifolius (Mill.) I.M. Johnst).
    Abstract Introduction: Introduction: noncommunicable diseases (NCDs) are the main cause of death worldwide. Secondary metabolites from plant sources such as Cnidoscolus aconitifolius may be used as adjuvants in the prevention of diseases related to oxidative stress and inflammation such as NCDs. Objective: the in vitro antioxidant and anti-inflammatory activities associated with biologically active compounds in C. aconitifolius extracts were evaluated. Method: the contents of phenols, flavonoids, flavonones and hydroflavonoles were determined. The potential antioxidant activity was determined with 1,1-Diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays, and angiotensin-converting enzyme (ACE) activity. For anti-inflammatory activity quantitative PCR and enzyme-linked immunosorbent assay (ELISA) tests were used in macrophages derived from THP-1 monocytes and stimulated with LPS. Results: the aqueous extract recorded the highest phenolic content (70.61  0.07 g/100 g of extract), and the ethanolic extract registered the highest content in flavonoids (47.76  4.84 g/100 g of extract), flavonones and dihydroflavonoles (70.10  7.29 g/100 g of extract). The acetone extract obtained the highest DPPH inhibition (49.85 ± 5.30%), while the ethanolic extract showed the highest ABTS inhibition (41.01 ± 3.81%). The etanolic and aqueous extracts had the highest ACE inhibition. The ethanolic extract had the highest anti-inflammatory activity, decreasing gene expression for TNF- by 39.78% and for IL-6 by 97.81%, and their production by 46% and 48.38%, respectively, in macrophages stimulated with LPS. Conclusion: these extracts demonstrated in vitro their antioxidant and anti-inflammatory potential due to their content of bioactive compounds.
    MeSH term(s) Acetone ; Angiotensin-Converting Enzyme Inhibitors/pharmacology ; Anti-Inflammatory Agents, Non-Steroidal/pharmacology ; Antioxidants/pharmacology ; Biphenyl Compounds ; Ethanol ; Euphorbiaceae/chemistry ; Flavones/pharmacology ; Humans ; Lipopolysaccharides/pharmacology ; Macrophages/drug effects ; Phenols/pharmacology ; Picrates ; Plant Extracts/pharmacology ; Plant Leaves/chemistry ; Solvents
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors ; Anti-Inflammatory Agents, Non-Steroidal ; Antioxidants ; Biphenyl Compounds ; Flavones ; Lipopolysaccharides ; Phenols ; Picrates ; Plant Extracts ; Solvents ; Acetone (1364PS73AF) ; Ethanol (3K9958V90M) ; 1,1-diphenyl-2-picrylhydrazyl (DFD3H4VGDH)
    Language Spanish
    Publishing date 2019-12-11
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1481223-x
    ISSN 1699-5198 ; 0212-1611
    ISSN (online) 1699-5198
    ISSN 0212-1611
    DOI 10.20960/nh.02752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Biomass and lipid production from Chlorella vulgaris UTEX 26 cultivated in 2 m

    Ramírez-López, Citlally / Perales-Vela, Hugo Virgilio / Fernández-Linares, Luis

    Bioresource technology

    2018  Volume 274, Page(s) 252–260

    Abstract: A Chlorella vulgaris UTEX 26 semicontinuous culture was implemented in 2000 L raceways with M ... medium during spring season at greenhouse conditions. Areal biomass productivities between 20 and 26 g m ...

    Abstract A Chlorella vulgaris UTEX 26 semicontinuous culture was implemented in 2000 L raceways with M medium during spring season at greenhouse conditions. Areal biomass productivities between 20 and 26 g m
    MeSH term(s) Biomass ; Chlorella vulgaris/metabolism ; Lipids/biosynthesis ; Microalgae ; Photobioreactors ; Ponds ; Seasons
    Chemical Substances Lipids
    Language English
    Publishing date 2018-11-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1065195-0
    ISSN 1873-2976 ; 0960-8524
    ISSN (online) 1873-2976
    ISSN 0960-8524
    DOI 10.1016/j.biortech.2018.11.096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Thesis: Separation und phänotypische Charakterisierung intestinaler mononukleärer Zellen der Lamina propia [propria] aus Mukosa-Biopsaten von Patienten mit M. Crohn und Colitis ulcerosa

    Linares, Teresa

    1990  

    Title variant Separation und phänotypische Charakterisierung intestinaler mononukleärer Zellen der Lamina propia aus Mukosa-Biopsaten von Patienten mit M. Crohn und Colitis ulcerosa
    Author's details vorgelegt von Teresa Linares
    Size 60, [14] S. : graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 1991
    HBZ-ID HT004323749
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Availability of Non-English Language Telephone Recordings at Ambulatory Clinics.

    Linares, Miguel / Linares, Emily / Rodriguez, Jorge A

    Journal of general internal medicine

    2024  

    Language English
    Publishing date 2024-04-23
    Publishing country United States
    Document type Letter
    ZDB-ID 639008-0
    ISSN 1525-1497 ; 0884-8734
    ISSN (online) 1525-1497
    ISSN 0884-8734
    DOI 10.1007/s11606-024-08763-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Increase of the M phenotype among erythromycin-resistant Streptococcus pneumoniae isolates from Spain related to the serotype 14 variant of the Spain9V-3 clone.

    Ardanuy, C / Fenoll, A / Berrón, S / Calatayud, L / Liñares, J

    Antimicrobial agents and chemotherapy

    2006  Volume 50, Issue 9, Page(s) 3162–3165

    Abstract: ... Although the MLS(B) phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% (P < 0 ...

    Abstract Between 1998 and 2003 the rate of erythromycin resistance among pneumococci in Spain was 34.4%. Although the MLS(B) phenotype was prevalent (94.7%), the rate of the M phenotype increased from 3.3% to 8.9% (P < 0.01). Clonal dissemination of mef(E)-carrying strains of serotype 14 variant of the Spain(9V)-3 clone was the major contributor to this increase.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/genetics ; Drug Resistance, Bacterial ; Erythromycin/pharmacology ; Humans ; Membrane Proteins/genetics ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/microbiology ; Spain/epidemiology ; Streptococcus pneumoniae/classification ; Streptococcus pneumoniae/drug effects ; Streptococcus pneumoniae/genetics ; Streptococcus pneumoniae/isolation & purification
    Chemical Substances Anti-Bacterial Agents ; Bacterial Proteins ; MefA protein, Streptococcus ; Membrane Proteins ; Erythromycin (63937KV33D)
    Language English
    Publishing date 2006-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 217602-6
    ISSN 1098-6596 ; 0066-4804
    ISSN (online) 1098-6596
    ISSN 0066-4804
    DOI 10.1128/AAC.00269-06
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: XLVIII National Congress of the Sociedad Española de Enfermeria Intensiva y Unidades Coronarias.

    Del Barrio Linares, M

    Enfermeria intensiva

    2023  Volume 34, Issue 3, Page(s) 113–114

    Language English
    Publishing date 2023-09-08
    Publishing country Spain
    Document type Editorial
    ISSN 2529-9840
    ISSN (online) 2529-9840
    DOI 10.1016/j.enfie.2023.08.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: JUNTOS Radio: a podcast created in collaboration with Spanish-speaking healthcare providers, Juntos Center for Advancing Latino Health, and a medical librarian.

    Linares, Brenda M / Ramirez, Mariana

    Journal of the Medical Library Association : JMLA

    2023  Volume 111, Issue 4, Page(s) 831–832

    Abstract: Spanish speaking healthcare providers, JUNTOS Center for Advancing Latino Health, and a medical librarian partnered to create a podcast on essential health topics relevant to the Latinx community. The podcasts were recorded in Spanish and included ... ...

    Abstract Spanish speaking healthcare providers, JUNTOS Center for Advancing Latino Health, and a medical librarian partnered to create a podcast on essential health topics relevant to the Latinx community. The podcasts were recorded in Spanish and included Spanish supplementary consumer health information from credible resources such as MedlinePlus en Espanol. The podcasts covered important topics about COVID-19 such as vaccines, clinical trials, and social distancing. It also includes other relevant topics that are affecting the Latinx community.
    MeSH term(s) Humans ; Health Personnel ; Hispanic or Latino ; Librarians ; MedlinePlus ; Webcasts as Topic ; Health Education
    Language English
    Publishing date 2023-12-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2072435-4
    ISSN 1558-9439 ; 1536-5050
    ISSN (online) 1558-9439
    ISSN 1536-5050
    DOI 10.5195/jmla.2023.1653
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Genome-Wide Association Study Reveals a QTL Region for Ashy Stem Blight Resistance in PRA154 Andean Common Bean.

    Viteri, Diego M / Linares-Ramírez, Angela M / Shi, Ainong

    Plant disease

    2024  Volume 108, Issue 2, Page(s) 407–415

    Abstract: Ashy stem blight (ASB) caused ... ...

    Abstract Ashy stem blight (ASB) caused by
    MeSH term(s) Quantitative Trait Loci/genetics ; Genome-Wide Association Study ; Phaseolus/genetics ; Plant Breeding ; Chromosome Mapping
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-07-23-1275-RE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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