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Article: The Yin and Yang of the protein corona on the delivery journey of nanoparticles.

Wang, Yi-Feng / Zhou, Yaxin / Sun, JiaBei / Wang, Xiaotong / Jia, Yaru / Ge, Kun / Yan, Yan / Dawson, Kenneth A / Guo, Shutao / Zhang, Jinchao / Liang, Xing-Jie

Nano research

2022 , Page(s) 1–20

Abstract: Nanoparticles-based drug delivery systems have attracted significant attention in biomedical fields because they can deliver loaded cargoes to the target site in a controlled manner. However, tremendous challenges must still be overcome to reach the ... ...

Abstract	Nanoparticles-based drug delivery systems have attracted significant attention in biomedical fields because they can deliver loaded cargoes to the target site in a controlled manner. However, tremendous challenges must still be overcome to reach the expected targeting and therapeutic efficacy
Language	English
Publishing date	2022-09-16
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2442216-2
ISSN	1998-0000 ; 1998-0124
ISSN (online)	1998-0000
ISSN	1998-0124
DOI	10.1007/s12274-022-4849-6
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Article ; Online: Transcriptional regulation of human abraxas brother protein 1 expression by yin yang 1.

Song, Pan / Hong, Jian / Wang, Yuan / Yao, Xuelian / Zhan, Yiqun / Yin, Ronghua / Yu, Miao / Li, Changyan / Yang, Xiaoming / Ge, Changhui

Biochemistry and cell biology = Biochimie et biologie cellulaire

2020 Volume 99, Issue 2, Page(s) 223–230

Abstract: Abraxas brother protein 1 (ABRO1) is a subunit of the deubiquitinating enzyme BRCC36-containing isopeptidase complex and plays important roles in cellular responses to stress by interacting with its binding partners, such as ubiquitin-specific peptidase ... ...

Abstract	Abraxas brother protein 1 (ABRO1) is a subunit of the deubiquitinating enzyme BRCC36-containing isopeptidase complex and plays important roles in cellular responses to stress by interacting with its binding partners, such as ubiquitin-specific peptidase 7, p53, activating transcription factor 4, THAP-domain containing 5, and serine hydroxymethyltransferase. However, the transcriptional regulation of
MeSH term(s)	Animals ; Cell Line ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Nuclear Matrix-Associated Proteins/genetics ; Nuclear Matrix-Associated Proteins/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Ubiquitin-Specific Proteases/genetics ; Ubiquitin-Specific Proteases/metabolism ; YY1 Transcription Factor/metabolism
Chemical Substances	ABRAXAS2 protein, human ; Nuclear Matrix-Associated Proteins ; RNA, Messenger ; YY1 Transcription Factor ; YY1 protein, human ; Ubiquitin-Specific Proteases (EC 3.4.19.12)
Language	English
Publishing date	2020-08-26
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	54104-7
ISSN	1208-6002 ; 0829-8211
ISSN (online)	1208-6002
ISSN	0829-8211
DOI	10.1139/bcb-2019-0279
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Article ; Online: Study on the substance basis of the efficacy of eucommiae cortex before and after salt processing for the treatment of kidney-yang deficiency syndrome based on the spectrum-effect relationship.

Wu, Hangsha / Lv, Yue / Zhao, Mingfang / Tang, Rui / Li, Yafei / Fang, Keer / Wei, Feiyang / Ge, Weihong / Du, Weifeng / Li, Changyu / Zhang, Yefeng

Journal of ethnopharmacology

2023 Volume 318, Issue Pt A, Page(s) 116926

Abstract: Ethnopharmacological relevance: Kidney-Yang deficiency syndrome (KYDS) is one of the common ...

Abstract	Ethnopharmacological relevance: Kidney-Yang deficiency syndrome (KYDS) is one of the common diseases of the elderly and closely related to the ageing of the body, it has a major impact on the quality of life of the patient. Eucommiae Cortex (EC) is the dried bark of Eucommia ulmoides Oliv. Which has the effect of tonifying the liver and kidneys, strengthening the muscles and bones. In Traditional Chinese Medicine clinics, EC is commonly used in the treatment of KYDS, but the material basis for the improvement of its efficacy in treating KYDS after salt processing remains unclear. Aim of the study: This study aimed to find the main active ingredients that could improve the treatment of KYDS efficacy of EC after salt processing. Materials and methods: Firstly, the fingerprints of raw and salt-processed EC were established to determine the common components by using HPLC, and then an experimental study on the treatment of KYDS efficacy was carried out to compare the difference in the efficacy between raw and salt-processed EC. Thirdly, the spectrum-effect relationship of chemical components and pharmacodynamic indexes was established by using Grey Relational Analysis and Entropy Method. Finally, the network pharmacology and molecular docking technique was used to verify the kidney tonifying effect of the active ingredients of EC. Results: According to the results of the analysis of hormonal index levels on the hypothalamic-pituitary-target gland axis and the extent of renal lesions, the therapeutic effect of EC on KYDS was mainly reflected in the regulation of the Adrenocorticotropic hormone, Corticosterone in the hypothalamic-pituitary-adrenal axis and Tri-iodothyronine, Tetra-iodothyronine in the hypothalamic-pituitary-thyroid axis, moreover the therapeutic effect of salt-processed EC was stronger than that of raw EC. The pharmacologically active ingredients that improved its treatment of KYDS efficacy after salt processing were peak 1 (geniposidic acid), peak 2 (chlorogenic acid), peak 5 (geniposide), peak 6 (genipin), peak 7 (pinoresinol diglucoside) and peak 11 (hyperoside). Meanwhile, the results of network pharmacology and molecular docking showed that the 6 active ingredients could exert kidney tonic effects through multiple signaling pathways by acting on core targets such as AKT1 and PTGS2. Conclusion: As far as we known, this was the first time to establish and compare the spectrum-effect relationship between raw and salt-processed EC, which laid the foundation for the pharmacokinetics studies of EC and provided a reference for future EC studies.
MeSH term(s)	Humans ; Aged ; Yang Deficiency/drug therapy ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Drugs, Chinese Herbal/chemistry ; Molecular Docking Simulation ; Hypothalamo-Hypophyseal System ; Quality of Life ; Pituitary-Adrenal System ; Kidney
Chemical Substances	Drugs, Chinese Herbal
Language	English
Publishing date	2023-07-20
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116926
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Article ; Online: Research on the effect of Dipsaci Radix before and after salt-processed on kidney yang deficiency syndrome rats and the preliminary mechanism study through the BMP-Smad signaling pathway.

Du, Weifeng / Lv, Yue / Wu, Hangsha / Li, Yafei / Tang, Rui / Zhao, Mingfang / Wei, Feiyang / Li, Changyu / Ge, Weihong

Journal of ethnopharmacology

2023 Volume 312, Page(s) 116480

Abstract: ... salt-processed with kidney yang deficiency syndrome (KYDS), and we selected the BMP-Smad ...

Abstract	Ethnopharmacological relevance: Dipsaci Radix (DR) is the dry root of Dipsacus asper Wall. ex DC. Aim of the study: The purpose of this study was to compare the effects of DR on rats before and after salt-processed with kidney yang deficiency syndrome (KYDS), and we selected the BMP-Smad signaling pathway to explore the mechanism of DR. Materials and methods: The model of KYDS was established by subcutaneous injection of hydrocortisone, the crude DR (CDR) and salt-processed DR (SDR) were given the corresponding dose (2 g/kg, 4 g/kg, and 6 g/kg). The organ index and the contents of adrenocorticotropic hormone (ACTH), cortistatin (CORT), thyroid hormone (T4), tumor necrosis factor-alpha (TNF-α), testosterone (T), estradiol (E2), cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP), Na Results: The results showed that compared with the model group, the thymus and kidney index, as well as the contents of ACTH, CORT, cAMP, GH, Na Conclusion: This study showed that both CDR and SDR could have a good therapeutic effect on KYDS, and SDR was better than CDR. This study chose the BMP-Smad signaling pathway to study the mechanism of DR in the treatment of KYDS and provided a scientific basis for the processing mechanism of salt-processed.
MeSH term(s)	Rats ; Animals ; Yang Deficiency/drug therapy ; Yang Deficiency/metabolism ; Bone Morphogenetic Protein 7 ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Tumor Necrosis Factor-alpha ; Kidney ; Glomerulonephritis/drug therapy ; Adrenocorticotropic Hormone ; Growth Hormone/therapeutic use
Chemical Substances	Bone Morphogenetic Protein 7 ; Drugs, Chinese Herbal ; Tumor Necrosis Factor-alpha ; Adrenocorticotropic Hormone (9002-60-2) ; Growth Hormone (9002-72-6)
Language	English
Publishing date	2023-04-14
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.116480
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Article ; Online: Ling-Yang-Gou-Teng-decoction prevents vascular dementia through inhibiting oxidative stress induced neurovascular coupling dysfunction.

Zhao, Xin / Liu, Jinyu / Yang, Shijun / Song, Dandan / Wang, Chen / Chen, Chen / Li, Xiaoya / Wang, Qiuting / Ge, Shasha / Yang, Runmei / Liu, Xiuhua / Lin, Yulin / Cai, Dayong

Journal of ethnopharmacology

2018 Volume 222, Page(s) 229–238

Abstract: ... involves in the pathogenesis of VaD. Currently, there is no specific drug for VaD. Ling-Yang-Gou-Teng ...

Abstract	Ethnopharmacological relevance: Vascular dementia (VaD) is the common cognitive disorder derived mainly from lacunar stroke (LS). The oxidative stress induced neurovascular coupling (NVC) dysfunction involves in the pathogenesis of VaD. Currently, there is no specific drug for VaD. Ling-Yang-Gou-Teng -Decoction (LG), a well-known traditional Chinese formula, has been used for preventing VaD in clinic. Aim of the study: In this study, we aimed to investigate the underlying mechanism of LG on VaD in rats. Materials and method: VaD was replicated with autologous micro-thrombi against the background of hypercholesterolemia induced with high fatty diet. PTX (68.90 mg/kg/day), LG with three dosages (2.58, 8.14, 25.80 g/kg/day) was orally administrated to VaD rats, respectively. The NVC sensitivity was defined as the ratio of the microcirculative cerebral blood velocity (CBV) to the electroencephalograph (EEG) before and after penicillin stimulation. Behavioral performance, pathological changes of brain and oxidation related molecules were detected to assess the effects of LG on VaD. Results: LG exhibited beneficial effects on the VaD, which was demonstrated as improved exploratory, learning and memory abilities, relieved vascular or neural pathological changes in cerebral cortex or hippocampus. LG maintained NVC sensitivity, which was confirmed as significantly increased ΔCBV and the elevated ratio of ΔCBV/ΔqEEG. The underlying mechanisms of LG was associated with antioxidant effects, which was confirmed as significantly decreased nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) expression, and increased superoxide dismutase 3 (SOD3) expression. LG also reduced iNOS, increased nNOS and eNOS expression to restore NO bioavailability. Conclusions: The results suggested that LG prevented VaD may associate with inhibiting oxidative stress, protecting NO bioavailability, and then maintaining NVC sensitivity.
MeSH term(s)	Animals ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Brain/drug effects ; Brain/metabolism ; Brain/pathology ; Dementia, Vascular/drug therapy ; Dementia, Vascular/genetics ; Dementia, Vascular/metabolism ; Dementia, Vascular/pathology ; Male ; Maze Learning/drug effects ; NADPH Oxidase 2/genetics ; NADPH Oxidase 2/metabolism ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/therapeutic use ; Neurovascular Coupling/drug effects ; Nitric Oxide Synthase Type I/genetics ; Nitric Oxide Synthase Type I/metabolism ; Nitric Oxide Synthase Type II/genetics ; Nitric Oxide Synthase Type II/metabolism ; Nitric Oxide Synthase Type III/genetics ; Nitric Oxide Synthase Type III/metabolism ; Oxidative Stress/drug effects ; Plant Exudates/pharmacology ; Plant Exudates/therapeutic use ; Rats, Wistar ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism
Chemical Substances	Antioxidants ; Neuroprotective Agents ; Plant Exudates ; Nitric Oxide Synthase Type I (EC 1.14.13.39) ; Nitric Oxide Synthase Type II (EC 1.14.13.39) ; Nitric Oxide Synthase Type III (EC 1.14.13.39) ; Nos2 protein, rat (EC 1.14.13.39) ; Nos3 protein, rat (EC 1.14.13.39) ; Sod3 protein, rat (EC 1.15.1.1) ; Superoxide Dismutase (EC 1.15.1.1) ; Cybb protein, rat (EC 1.6.3.-) ; NADPH Oxidase 2 (EC 1.6.3.-)
Language	English
Publishing date	2018-03-13
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2018.03.015
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Article ; Online: ℤ3 parafermionic chain emerging from Yang-Baxter equation.

Yu, Li-Wei / Ge, Mo-Lin

Scientific reports

2016 Volume 6, Page(s) 21497

Abstract: We construct the 1D ℤ3 parafermionic model based on the solution of Yang-Baxter equation and ... from Yang-Baxter equation. On the other hand, to show the algebra of parafermionic tripling intuitively ... we define a new 3-body Hamiltonian H123 based on Yang-Baxter equation. Different from the Majorana doubling ...

Abstract	We construct the 1D ℤ3 parafermionic model based on the solution of Yang-Baxter equation and express the model by three types of fermions. It is shown that the ℤ3 parafermionic chain possesses both triple degenerate ground states and non-trivial topological winding number. Hence, the ℤ3 parafermionic model is a direct generalization of 1D ℤ2 Kitaev model. Both the ℤ2 and ℤ3 model can be obtained from Yang-Baxter equation. On the other hand, to show the algebra of parafermionic tripling intuitively, we define a new 3-body Hamiltonian H123 based on Yang-Baxter equation. Different from the Majorana doubling, the H123 holds triple degeneracy at each of energy levels. The triple degeneracy is protected by two symmetry operators of the system, ω-parity P [formula in text] and emergent parafermionic operator Γ, which are the generalizations of parity PM and emergent Majorana operator in Lee-Wilczek model, respectively. Both the ℤ3 parafermionic model and H123 can be viewed as SU(3) models in color space. In comparison with the Majorana models for SU(2), it turns out that the SU(3) models are truly the generalization of Majorana models resultant from Yang-Baxter equation.
Language	English
Publishing date	2016-02-23
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/srep21497
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Article ; Online: Fish Consumption and Health: The Yin and Yang.

Parian, Alyssa M / Mullin, Gerard E

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

2016 Volume 31, Issue 4, Page(s) 562–565

MeSH term(s)	Adult ; Animals ; Child ; Fatty Acids, Omega-3/administration & dosage ; Female ; Fishes ; Health Status ; Humans ; Male ; Mercury ; Pregnancy ; Seafood
Chemical Substances	Fatty Acids, Omega-3 ; Mercury (FXS1BY2PGL)
Language	English
Publishing date	2016-08
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	645074-x
ISSN	1941-2452 ; 0884-5336
ISSN (online)	1941-2452
ISSN	0884-5336
DOI	10.1177/0884533616651069
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Article ; Online: Sishen Pill Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis with Spleen-Kidney Yang Deficiency Syndromes

Wei Ge / Bu-Gao Zhou / You-Bao Zhong / Su-Qing Liu / Jia-Qi Huang / Wang-Yuan Yuan / Chang-Ying Xie / Duan-Yong Liu / Hai-Yan Wang / Zheng-Yun Zuo

Evidence-Based Complementary and Alternative Medicine, Vol

Role of Gut Microbiota, Fecal Metabolites, Inflammatory Dendritic Cells, and TLR4/NF-κB Pathway

2022 Volume 2022

Abstract: ... yang deficiency (SKYD) syndromes. However, its exact mechanism of action has not yet been fully elucidated ...

Abstract	Sishen pill (SSP) is an old Chinese medicine used to treat colitis with spleen-kidney-yang deficiency (SKYD) syndromes. However, its exact mechanism of action has not yet been fully elucidated. The aim of this study was to evaluate the effects and potential mechanisms of SSP on colitis with SKYD syndromes in mice. Colitis with SKYD syndromes was induced by rhubarb, hydrocortisone, and dextran sulfate sodium (DSS), and treatment was provided with SSP. Flow cytometry was performed to examine the inflammatory dendritic cell (infDC) regulations of SSP. The changes in the gut microbiota (GM) and fecal metabolites post-SSP treatment were investigated using the combination of 16S rRNA sequencing and untargeted metabolomics. Additionally, we also examined whether SSPs could regulate the infDCs by modifying TLR4/NF-κB signaling pathways. Compared with the DSS group, the disease activity index, colonic weight, index of colonic weight, and colonic injury scores, as well as the levels of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-6, and IL-12p70 decreased significantly in the DSS + SSP group, while free triiodothyronine (FT3), free tetraiodothyronine (FT4), testosterone (TESTO), body weight change, colonic length, and the levels of IL-10 increased. Also, SSP decreased the amounts of CD103+CD11c+iNOS+, CD103+CD11c+TNF-α+, CD11c+CD103+CD324+, CD103+CD11c+MHC-II+, and CD103+CD11c+CD115+. Interestingly, 16S rRNA sequencing and untargeted metabolomics showed that SSP treatment restored the dysbiosis of GM and improved the dysfunction in fecal metabolism in colitis mice with SKYD syndromes. Correlation analysis indicated that the modulatory effects of SSP on FT3, FT4, IL-10, colonic weight index, CD103+CD11c+TNF-α+, CD103+CD11c+MHC-II+, and 13 common differential metabolites were related to alterations in the abundance of Parvibacter, Aerococcus, norank_f_Lachnospiraceae, Lachnospiraceae_UCG-006, Akkermansia, and Rhodococcus in the GM. In addition, SSP markedly inhibited the activation of the TLR4, MyD88, TRAF6, TAB2, ...
Keywords	Other systems of medicine ; RZ201-999
Subject code	630
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Sishen Pill Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis with Spleen-Kidney Yang Deficiency Syndromes: Role of Gut Microbiota, Fecal Metabolites, Inflammatory Dendritic Cells, and TLR4/NF-

Ge, Wei / Zhou, Bu-Gao / Zhong, You-Bao / Liu, Su-Qing / Huang, Jia-Qi / Yuan, Wang-Yuan / Xie, Chang-Ying / Liu, Duan-Yong / Wang, Hai-Yan / Zuo, Zheng-Yun

Evidence-based complementary and alternative medicine : eCAM

2022 Volume 2022, Page(s) 6132289

Abstract: ... yang deficiency (SKYD) syndromes. However, its exact mechanism of action has not yet been fully elucidated ...

Abstract	Sishen pill (SSP) is an old Chinese medicine used to treat colitis with spleen-kidney-yang deficiency (SKYD) syndromes. However, its exact mechanism of action has not yet been fully elucidated. The aim of this study was to evaluate the effects and potential mechanisms of SSP on colitis with SKYD syndromes in mice. Colitis with SKYD syndromes was induced by rhubarb, hydrocortisone, and dextran sulfate sodium (DSS), and treatment was provided with SSP. Flow cytometry was performed to examine the inflammatory dendritic cell (infDC) regulations of SSP. The changes in the gut microbiota (GM) and fecal metabolites post-SSP treatment were investigated using the combination of 16S rRNA sequencing and untargeted metabolomics. Additionally, we also examined whether SSPs could regulate the infDCs by modifying TLR4/NF-
Language	English
Publishing date	2022-10-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2022/6132289
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Article: Ling-Yang-Gou-Teng-decoction prevents vascular dementia through inhibiting oxidative stress induced neurovascular coupling dysfunction

Zhao, Xin / Chen Chen / Chen Wang / Dandan Song / Dayong Cai / Jinyu Liu / Qiuting Wang / Runmei Yang / Shasha Ge / Shijun Yang / Xiaoya Li / Xiuhua Liu / Yulin Lin

Journal of ethnopharmacology. 2018 Aug. 10, v. 222

2018

Abstract: ... there is no specific drug for VaD. Ling-Yang-Gou-Teng -Decoction (LG), a well-known traditional Chinese ...

Abstract	Vascular dementia (VaD) is the common cognitive disorder derived mainly from lacunar stroke (LS). The oxidative stress induced neurovascular coupling (NVC) dysfunction involves in the pathogenesis of VaD. Currently, there is no specific drug for VaD. Ling-Yang-Gou-Teng -Decoction (LG), a well-known traditional Chinese formula, has been used for preventing VaD in clinic.In this study, we aimed to investigate the underlying mechanism of LG on VaD in rats.VaD was replicated with autologous micro-thrombi against the background of hypercholesterolemia induced with high fatty diet. PTX (68.90 mg/kg/day), LG with three dosages (2.58, 8.14, 25.80 g/kg/day) was orally administrated to VaD rats, respectively. The NVC sensitivity was defined as the ratio of the microcirculative cerebral blood velocity (CBV) to the electroencephalograph (EEG) before and after penicillin stimulation. Behavioral performance, pathological changes of brain and oxidation related molecules were detected to assess the effects of LG on VaD.LG exhibited beneficial effects on the VaD, which was demonstrated as improved exploratory, learning and memory abilities, relieved vascular or neural pathological changes in cerebral cortex or hippocampus. LG maintained NVC sensitivity, which was confirmed as significantly increased ΔCBV and the elevated ratio of ΔCBV/ΔqEEG. The underlying mechanisms of LG was associated with antioxidant effects, which was confirmed as significantly decreased nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) expression, and increased superoxide dismutase 3 (SOD3) expression. LG also reduced iNOS, increased nNOS and eNOS expression to restore NO bioavailability.The results suggested that LG prevented VaD may associate with inhibiting oxidative stress, protecting NO bioavailability, and then maintaining NVC sensitivity.
Keywords	antioxidant activity ; bioavailability ; blood ; cerebral cortex ; cognitive disorders ; dementia ; diet ; drugs ; electroencephalography ; endothelial nitric oxide synthase ; hippocampus ; hypercholesterolemia ; inducible nitric oxide synthase ; memory ; NADP (coenzyme) ; neuronal nitric oxide synthase ; nitric oxide ; oxidation ; oxidative stress ; pathogenesis ; penicillins ; rats ; stroke ; superoxide dismutase ; traditional medicine
Language	English
Dates of publication	2018-0810
Size	p. 229-238.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2018.03.015
Database	NAL-Catalogue (AGRICOLA)

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