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Article: Novel Anthropometric Indices as Screening Tools for Obesity: A Study on Healthy Iranians.

Alirezaei, Toktam / Soori, Hamid / Irilouzadian, Rana / Najafimehr, Hadis

2023 Volume 2023, Page(s) 6612411

Abstract: Background and aims: Upper body fat distribution is more related to cardiometabolic diseases than central obesity. Neck circumference (NC) and neck-to-height ratio (NHtR) are two indicators of upper body obesity that are affordable, easy to obtain, ... ...

Abstract	Background and aims: Upper body fat distribution is more related to cardiometabolic diseases than central obesity. Neck circumference (NC) and neck-to-height ratio (NHtR) are two indicators of upper body obesity that are affordable, easy to obtain, highly reproducible, and more practical in the crowded health centers than the classic anthropometric indices. Methods: 18-65-year-old individuals with no past medical history were included. After obtaining written informed consent, they were screened for hypertension, high blood glucose, and other abnormal laboratory results. Data were analyzed using SPSS and Mann-Whitney Results: In our 2,812 participants, NC had the lowest area under the curve (AUC) in both male and female obese and overweight subjects. NHtR and hip circumference (HC) had the highest AUC in men and women with obesity, respectively. The highest sensitivity for overweight men and women belonged to waist circumference (WC) and waist-to-height ratio (WHtR), respectively, and for both males and females with obesity, NHtR had the highest sensitivity. The cutoff point of NHtR had the same value for males and females. HC and NHtR had the highest positive likelihood ratio (PLR) for obesity in men. In addition, HC and WC had the highest PLR for obesity in women. Conclusion: In this study, we revealed that NC had the lowest and NHtR and HC had the highest predictive value for obesity. Furthermore, for both males and females with obesity, NHtR had the highest sensitivity. HC had the highest PLR for obesity in both genders. Our results warrant prospective studies to evaluate the role of NHtR and other novel anthropometric indices in the risk of cardiometabolic diseases.
Language	English
Publishing date	2023-10-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2573563-9
ISSN	2090-0732 ; 2090-0724
ISSN (online)	2090-0732
ISSN	2090-0724
DOI	10.1155/2023/6612411
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Comparative analysis of anthropometric indices with serum uric acid in Iranian healthy population.

Soori, Hamid / Rezapoor, Parinaz / Najafimehr, Hadis / Alirezaei, Toktam / Irilouzadian, Rana

Journal of clinical laboratory analysis

2022 Volume 36, Issue 2, Page(s) e24246

Abstract: Background: The relationship between elevated serum uric acid (SUA) levels and hypertension, metabolic syndrome and cardiovascular disease has been established. In this study, the relation of SUA levels to anthropometric indices, blood cell count and ... ...

Abstract	Background: The relationship between elevated serum uric acid (SUA) levels and hypertension, metabolic syndrome and cardiovascular disease has been established. In this study, the relation of SUA levels to anthropometric indices, blood cell count and lipid profile was examined. Methods: Anthropometric parameters including body-mass index, waist circumference, waist to height ratio, waist to hip ratio, waist to pelvic ratio, neck circumference (NC), body fat mass (BFM), basal metabolic rate (BMR), visceral fat level (VFL) and percent body fat (PBF), along with complete blood cell count, lipid profile and SUA were obtained from 2921 young and middle-aged Iranian healthy subjects. To assess the normality of data, the Kolmogorov-Smirnov test was used. Mann-Whitney, Kruskal-Wallis, Chi-square and Spearman correlation tests were used for evaluating the association between variables. Simple and multiple regression analyses were also performed. Results: The results of data analysis showed all studied factors were correlated with SUA level except VFL, BFM, and platelet-to-lymphocyte ratio. The highest correlation was with NC, BMR, hematocrits (HCT) and triglycerides (TG). The backward method revealed that TG, LDL, HDL, neutrophil, lymphocyte, platelet, HCT, BMR and skinfold fat thickness were factors related to SUA. Conclusions: According to the finding of this study, SUA level is related to anthropometric indices, lipid profile and neutrophil to lymphocyte ratio in healthy population. SUA measurement might be advisable to identify those at increased risk of health problems whom might benefit from further evaluation.
MeSH term(s)	Adult ; Anthropometry ; Biomarkers/blood ; Blood Platelets ; Body Weights and Measures ; Cross-Sectional Studies ; Female ; Humans ; Iran ; Lipids/blood ; Lymphocytes ; Male ; Middle Aged ; Neutrophils ; Pilot Projects ; Uric Acid/blood
Chemical Substances	Biomarkers ; Lipids ; Uric Acid (268B43MJ25)
Language	English
Publishing date	2022-01-16
Publishing country	United States
Document type	Comparative Study ; Journal Article
ZDB-ID	645095-7
ISSN	1098-2825 ; 0887-8013
ISSN (online)	1098-2825
ISSN	0887-8013
DOI	10.1002/jcla.24246
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Article ; Online: Estimation of basic reproduction number for COVID-19 and the reasons for its differences.

Najafimehr, Hadis / Mohamed Ali, Kosar / Safari, Saeed / Yousefifard, Mahmoud / Hosseini, Mostafa

International journal of clinical practice

2020 Volume 74, Issue 8, Page(s) e13518

Keywords	covid19
Language	English
Publishing date	2020-04-16
Publishing country	India
Document type	Letter
ZDB-ID	1386246-7
ISSN	1742-1241 ; 1368-5031
ISSN (online)	1742-1241
ISSN	1368-5031
DOI	10.1111/ijcp.13518
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Article: Iranian high risk regions due to esophageal cancer: spatial analysis of cancer registry data.

Najafimehr, Hadis / Ashtari, Sara / Pourhoseingholi, Mohamad Amin / Busani, Luca

Gastroenterology and hepatology from bed to bench

2019 Volume 11, Issue Suppl 1, Page(s) S25–S31

Abstract: Aim: The aim of this study was to identify the esophageal cancer (EC) high risk regions to evaluate changes of relative risks (RRs) for both genders by time in Iranian provinces.: Background: EC is one of the public health problems in Iran. In spite ... ...

Abstract	Aim: The aim of this study was to identify the esophageal cancer (EC) high risk regions to evaluate changes of relative risks (RRs) for both genders by time in Iranian provinces. Background: EC is one of the public health problems in Iran. In spite of this fact, there is not comprehensive study estimating RRs across the Iranian provinces. Methods: In this cross-sectional study the data for EC cases were extracted from Ministry of Health and Medical Education (MOHME) including 30 provinces from 2004 to 2010. For estimating the model parameters, we used Bayesian approach by regarding spatial correlations of adjacent provinces. Results: The Northern half of Iran has high risk and other half has low risk. During the time, the range of RRs has decreased for both gender and also the dispersion of EC is decreasing for women but nearly is fixed for men. Conclusion: While RR has declined during the study, focusing on the Northern half of Iran as high risk regions is a considerable fact for policymakers.
Language	English
Publishing date	2019-01-22
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2569124-7
ISSN	2008-4234 ; 2008-2258
ISSN (online)	2008-4234
ISSN	2008-2258
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Article ; Online: The Effect of Sleep Quality on Mental Health Among Clinical and Non-Clinical Staffs

Hadis Najafimehr / Hamid Soori / Narges Naghavi / Reyhaneh Sadat Jafarian Bahri / Mohammad Taghi Yasami

Acta Medica Iranica, Vol 59, Iss

2021 Volume 1

Abstract: Sleep quality plays an important role in people's mental health. Until now, the comparison of factors affecting mental health among clinical and non-clinical workers has received less attention. This study aimed to investigate the relationship between ... ...

Abstract	Sleep quality plays an important role in people's mental health. Until now, the comparison of factors affecting mental health among clinical and non-clinical workers has received less attention. This study aimed to investigate the relationship between sleep quality and mental health and factors affecting mental health in a large working population. The present study was derived from the first phase of a cohort study of Shahid Beheshti University of Medical Sciences staff in 2019. Participants included 2921 employees. Demographic variables and job characteristics, the Pittsburgh Sleep Quality Index (PSQI) and General Health Questionnaire-28 (GHQ-28) were used for data collection. For finding factors affecting mental health, logistic regression was used. Clinical workers had lower mental health (P<0.001) and lower sleep quality (P=0.04) than others. The relationship between mental health and sleep quality was significant (P<0.001). The prevalence of poor sleep quality was 35.6% and for undesirable mental health was 27.8%. Marital status had a significant relationship with mental health (P=0.02). The chance of undesirable mental health decreased with age (OR: 0.98 (0.97, 0.99)). Women had twice undesirable mental health than men (OR: 1.99 (1.62, 2.50)). The odds of undesirable mental health in staff with poor sleep quality were about five times higher than others (OR: 4.80 (3.99, 5.76)). Sleep quality may be considered as a factor affecting mental health. Due to the importance of the issue, planning for the improvement of clinical workers' sleep quality seems to be necessary by health policymakers.
Keywords	Employee ; Job ; Mental health ; Sleep ; Medicine (General) ; R5-920
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Tehran University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Clinical decision rules in predicting computed tomography scan findings and need for neurosurgical intervention in mild traumatic brain injury: a prospective observational study.

Forouzannia, Seyed Mohammad / Najafimehr, Hadis / Oskooi, Rosita Khatamian / Faridaalaee, Gholamreza / Dizaji, Shayan Roshdi / Toloui, Amirmohammad / Forouzannia, Seyed Ali / Alavi, Seyedeh Niloufar Rafiei / Alizadeh, Mohammadreza / Safari, Saeed / Baratloo, Alireza / Yousefifard, Mahmoud / Hosseini, Mostafa

European journal of trauma and emergency surgery : official publication of the European Trauma Society

2023

Abstract: Purpose: In this study, we will compare the diagnostic values of head CT decision rules in predicting the findings of CT scans in a prospective multicenter study in university emergency departments in Iran.: Methods: The primary outcome was any ... ...

Abstract	Purpose: In this study, we will compare the diagnostic values of head CT decision rules in predicting the findings of CT scans in a prospective multicenter study in university emergency departments in Iran. Methods: The primary outcome was any traumatic lesion findings in brain CT scans, and the secondary outcomes were death, the need for mechanical ventilation, and neurosurgical intervention. Decision rules including the Canadian CT Head Rule (CCHR), New Orleans Criteria (NOC), National Institute for Health and Clinical Excellence (NICE), National Emergency X-Radiography Utilization Study (NEXUS), and Neurotraumatology Committee of the World Federation of Neurosurgical Societies (NCWFNS) were compared for the main outcomes. Results: In total, 434 mild TBI patients were enrolled in the study. The NCWFNS had the highest sensitivity (91.14%) and the lowest specificity (39.42%) for predicting abnormal finding in CT scan compared to other models. While the NICE obtained the lowest sensitivity (79.75%), it was associated with the highest specificity (66.67%). All model performances were improved when administered to predict neurosurgical intervention among patients with GCS 13-15. NEXUS (AUC 0.862, 95% CI 0.799-0.924) and NCWFNS (AUC 0.813, 95% CI 0.723-0.903) had the best performance among all evaluated models. Conclusion: The NCWFNS and the NEXUS decision rules performed better than the CCHR and NICE guidelines for predicting any lesion in the CT imaging and neurosurgical intervention among patients with mTBI with GCS 13-15. For a subset of mTBI patients with GCS 15, the NOC criteria have higher sensitivity for abnormal CT imaging, but lower specificity and more requested CTs.
Language	English
Publishing date	2023-09-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2275480-5
ISSN	1863-9941 ; 1863-9933
ISSN (online)	1863-9941
ISSN	1863-9933
DOI	10.1007/s00068-023-02373-y
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Article: The spatial distribution of colorectal cancer relative risk in Iran: a nationwide spatial study.

Pourhoseingholi, Mohamad Amin / Najafimehr, Hadis / Kavousi, Amir / Pasharavesh, Leila / Khanabadi, Binazir

Gastroenterology and hepatology from bed to bench

2020 Volume 13, Issue Suppl1, Page(s) S40–S46

Abstract: Aim: The aim of this study was to estimate the standardized incidence rate (SIR) and also the relative risk (RR) of colorectal cancer (CRC) in Iran and to determine the distribution of CRC risk in a map after adjusting socioeconomic risk factors.: ... ...

Abstract	Aim: The aim of this study was to estimate the standardized incidence rate (SIR) and also the relative risk (RR) of colorectal cancer (CRC) in Iran and to determine the distribution of CRC risk in a map after adjusting socioeconomic risk factors. Background: The growth of CRC incidence rate in Iran is a major public health problem and identifying high-risk regions is essential for further intervention. Methods: For this cross-sectional study, all CRC cases that occurred in 30 Iranian provinces between 2005 and 2008 were collected according to the International Classification of Diseases (ICD-10). In addition, socioeconomic information was extracted from statistical center of Iran. Bayesian and Poison regression models were fitted to identify significant covariates. For RR estimating, the spatial analysis using GIS technique was carried out. Results: The Bayesian method with increasing precision of the parameter estimates had a better fit. According to spatial model, East Azerbaijan province had a high (11.14) and South Khorasan province had a low (0.22) risk of CRC in the period of study. SIR for the male population was 1.92 ± 3.25, and for the female population it was 1.85 ± 3.37. Conclusion: There is a non-uniform spatial pattern of CRC risk in Iran. According to the results, North, Northwest and some parts of West and Central provinces of Iran are identified as high-risk areas; thus, it is recommended that health policymakers, especially in these areas, have more intervention measures. Further studies are needed to map the RR adjusted for nutrition factors.
Language	English
Publishing date	2020-05-28
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2569124-7
ISSN	2008-4234 ; 2008-2258
ISSN (online)	2008-4234
ISSN	2008-2258
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Effect of COPD on Health-Related Quality of Life; Results from the BOLD Study in Iran.

Sharifi, Hooman / Ghanei, Mostafa / Jamaati, Hamidreza / Masjedi, Mohammad Reza / Najafimehr, Hadis / Fakharian, Atefeh / Aryanpour, Mahshid / Buist, A Sonia

Tanaffos

2021 Volume 20, Issue 1, Page(s) 51–58

Abstract: Background: Chronic obstructive pulmonary disease (COPD) has been the third leading cause of morbidity and the sixth leading cause of mortality in 2020. This chronic disease usually impairs health status and is an independent predictor of morbidity and ... ...

Abstract	Background: Chronic obstructive pulmonary disease (COPD) has been the third leading cause of morbidity and the sixth leading cause of mortality in 2020. This chronic disease usually impairs health status and is an independent predictor of morbidity and mortality. The main objective of this study was to assess health-Related quality of life (HRQL) in a large sample of participants with and without COPD. Materials and methods: The present study was based on the data obtained from the population-based BOLD study in Iran. The sampling frame in this study included the whole population of 31 provinces of Iran. Participants were recruited using a stratified cluster sampling strategy with proportional allocations within strata. All the participants were requested to fill the Short Form 12 (SF-12) Health Survey Questionnaire, an abbreviated version of the SF-36. Results: A total of 1062 subjects, including 479 (45%) males and 583 (54.7%) females, were enrolled in the study. The mean age of the participants was 40±15.04 years. The overall COPD prevalence based on the post-bronchodilator spirometry functional criteria was 5.0%. The mean PCS- 12 and MCS- 12 for all the subjects were 66.61±22.72 and 60.79±23.52, respectively. The mean scores of PCS and MCS were significantly lower in patients with COPD than those without COPD (P<0.001). Conclusion: The findings of this study demonstrated that COPD, female gender, and an age above 40 years influenced HRQL, especially the physical dimension, as shown by the SF-12 instrument.
Language	English
Publishing date	2021-07-27
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2233372-1
ISSN	1735-0344
ISSN	1735-0344
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: A Systematic Review and Meta-Analysis on the Association between Inflammatory Bowel Disease Family History and Colorectal Cancer.

Najafimehr, Hadis / Aghdaei, Hamid Asadzadeh / Pourhoseingholi, Mohamad Amin / Shalmani, Hamid Mohaghegh / Vahedian-Azimi, Amir / Kroh, Matthew / Zali, Mohammad Reza / Sahebkar, Amirhossein

Gastroenterology research and practice

2021 Volume 2021, Page(s) 4874459

Abstract: Background: Colorectal cancer (CRC) and inflammatory bowel disease (IBD) are closely interrelated. However, the effect of having a family history of one disease on the risk of another remains undetermined.: Aim: The purpose of this meta-analysis was ... ...

Abstract	Background: Colorectal cancer (CRC) and inflammatory bowel disease (IBD) are closely interrelated. However, the effect of having a family history of one disease on the risk of another remains undetermined. Aim: The purpose of this meta-analysis was to estimate the prevalence of a family history of CRC among patients with IBD, as well as the prevalence of a family history of IBD among patients with CRC. Methods: PubMed, Scopus, Embase, Web of Science, and Google Scholar were searched to identify studies reporting the prevalence of family history of IBD among patients with CRC, in addition to the prevalence of family history of CRC among IBD patients. Criteria for study inclusion consisted of the following: (1) studies that evaluated either IBD or CRC and dysplasia, (2) included all age groups, and (3) evaluated the family history effects for IBD or CRC. The total number of IBD patients and IBD patients with a family history of CRC and the total number of CRC patients and CRC patients with a family history of IBD were reviewed. The pooled prevalence of diseases was also estimated according to degree of relatives and geographical area. Random-effects models were used for estimating pooled prevalence. Results: A total of 27 studies were included with 26,576 IBD and 9,181 CRC or dysplasia patients. Eligible studies included 13 case-control, 10 cohort, and 4 cross-sectional types. The pooled prevalence of a family history of CRC among patients with IBD was 6% (95% CI: 4-9%). The pooled prevalence for first- and second-degree relatives (11%, 95% CI: 0-37%) was more than that for the other relative subgroups of relatedness degree. The prevalence in the American regions (8% (95% CI: 5-13%)) was higher than that in the others. The pooled prevalence for a family history of IBD among CRC or dysplasia patients was 11% (95% CI: 6-16%). The pooled prevalence for first-degree relatives (13% (95% CI: 3-28%) was higher than that for the other relative subgroups of relatedness degree; it was also greater in American countries (15%, 95% CI: 8-23%). Conclusion: This study emphasizes the relationship between a family history of IBD and CRC development. Additionally, there was notable prevalence for a family history of CRC among IBD patients. American countries and first-degree relatives were identified to have a higher prevalence for both disease processes.
Language	English
Publishing date	2021-10-23
Publishing country	Egypt
Document type	Journal Article ; Review
ZDB-ID	2435460-0
ISSN	1687-630X ; 1687-6121
ISSN (online)	1687-630X
ISSN	1687-6121
DOI	10.1155/2021/4874459
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Estimation of basic reproduction number for COVID-19 and the reasons for its differences

Najafimehr, Hadis / Mohamed Ali, Kosar / Safari, Saeed / Yousefifard, Mahmoud / Hosseini, Mostafa

Int J Clin Pract

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #66343
Database	COVID19

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