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Article ; Online: STILLBIRTH RATE AND INFANT MORTALITY RATE: STUDY IN THE REGIONS OF UKRAINE MOST INTENSIVELY RADIOCONTAMINATED UPON THE CHORNOBYL NPP ACCIDENT.

Gunko, N V / Korotkova, N V / Masiuk, S V

Problemy radiatsiinoi medytsyny ta radiobiolohii

2023 Volume 28, Page(s) 143–157

Abstract: Objective: to evaluate the time pattern peculiarities of stillbirth and infant mortality rates in the radiocontaminated territories of Ukraine in the post-accident period on the basis of the national State Statistics Service data.: Object of the study! ...

Title translation	МЕРТВОНАРОДЖУВАНІСТЬ ТА МАЛЮКОВА СМЕРТНОСТЬ: ДОСЛІДЖЕННЯ РАЙОНІВ УКРАЇНИ НАЙБІЛЬШ РАДІОАКТИВНО ЗАБРУДНЕНИХ ВНАСЛІДОК АВАРІЇ НА ЧОРНОБИЛЬСЬКІЙ АЕС.
Abstract	Objective: to evaluate the time pattern peculiarities of stillbirth and infant mortality rates in the radiocontaminated territories of Ukraine in the post-accident period on the basis of the national State Statistics Service data. Object of the study: stillbirth and infant mortality rates of population of the most intensively radiocontaminated territories of Ukraine (Lughinskyi, Narodytskyi, Ovrutskyi and Olevskyi districts of Zhytomyrska oblast, Vyshgorodskyi, Ivankivskyi and Poliskyi districts of Kyivska oblast, Rokytnivskyi and Sarnenskyi districts of Rivnenska oblast, and Kozeletskyi and Rypkinskyi districts of Chernihivska oblast).Research materials and methods. Information resources of the State Statistics Service of Ukraine for 1986-2020 regarding the infant mortality and stillbirth rates were used in the study. Demographic, mathematical-statistical, graphical, and software-technological research methods were applies. Results and conclusions: Parameters of infant mortality and stillbirth rates for the 1986-2020 period were studied retrospectively. Significant variations in values were revealed both between the territories and years of survey.
MeSH term(s)	Infant ; Female ; Pregnancy ; Humans ; Stillbirth/epidemiology ; Retrospective Studies ; Ukraine/epidemiology ; Chernobyl Nuclear Accident ; Infant Mortality
Language	Ukrainian
Publishing date	2023-12-28
Publishing country	Ukraine
Document type	Journal Article
ISSN	2313-4607
ISSN (online)	2313-4607
DOI	10.33145/2304-8336-2023-28-143-157
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Article ; Online: An isotonic protein solution favorably modulated the porcine intestinal immune response and cellular adhesion markers and reduced PEDV shedding in vivo.

Masiuk, Dmytro M / Kokariev, Andrii V / Buzoianu, Stefan G / Firth, Ava M / Nedzvetsky, Victor S

Veterinary immunology and immunopathology

2024 Volume 271, Page(s) 110753

Abstract: Porcine epidemic diarrhea virus (PEDV) causes immensely large economic losses worldwide in the swine industry. PEDV attacks the intestine, disrupts intestinal epithelium morphology and barrier integrity, and results in profound diarrhea and high ... ...

Abstract	Porcine epidemic diarrhea virus (PEDV) causes immensely large economic losses worldwide in the swine industry. PEDV attacks the intestine, disrupts intestinal epithelium morphology and barrier integrity, and results in profound diarrhea and high mortality. A commercially available isotonic protein solution (IPS) (Tonisity Px) has anecdotally been reported to be effective in supportive treatment of piglets with active PEDV infections. This study evaluated the effects of supplementing (or not) the drinking water of 14 day old PEDV-infected piglets with the IPS on the content of E-cadherin, fibronectin, interferon-alpha (IFN-α), and matrix metalloproteinase 9 (MMP-9) in duodenal tissue. The content of PEDV DNA in feces was also measured. Though both groups had similar PEDV shedding at day 1, IPS piglets had significantly lower PEDV shedding at day 5, 14 and 21. The IPS group also had a shorter duration of PEDV virus shedding. Levels of E-cadherin and fibronectin, both of which are structural proteins in the intestine, remained unchanged from baseline in the IPS group, whereas the same molecules decreased significantly in the control group. IFN-α, an antiviral cytokine, and MMP-9, an enzyme that aids in tissue remodeling, were increased at days 5 and 14 post infection, and then decreased at day 21 post-infection in the IPS group compared to control. Overall, the IPS used in this study enhanced epithelial intercellular adhesion (E-cadherin) and extracellular matrix structure (fibronectin), resulted in significantand favorable changes in MMP-9 activity, and favorably modulated IFN-α production. This is the first report of this panel of biomarkers, especially MMP-9 and IFN-α, in the face of in vivo PEDV infection. This is also the first report to investigate a commercially available swine product that does not need to be administered in solid feed, and that is already registered for use throughout Asia, Europe, South America, and North America. Overall, the results of this study serve to clarify the behavior of 4 key biomarkers in the presence of in vivo PEDV infection. The results also indicate that IPS (Tonisity Px) supplementation is a viable intervention to modulate the porcine intestinal immune response with favorable effects on the intestine.
MeSH term(s)	Animals ; Swine ; Virus Shedding ; Porcine epidemic diarrhea virus/physiology ; Porcine epidemic diarrhea virus/immunology ; Coronavirus Infections/veterinary ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Swine Diseases/virology ; Swine Diseases/immunology ; Fibronectins/metabolism ; Matrix Metalloproteinase 9/metabolism ; Cadherins/metabolism ; Intestines/immunology ; Intestines/virology ; Interferon-alpha/immunology ; Cell Adhesion ; Intestinal Mucosa/immunology
Chemical Substances	Fibronectins ; Matrix Metalloproteinase 9 (EC 3.4.24.35) ; Cadherins ; Interferon-alpha
Language	English
Publishing date	2024-04-06
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	754160-0
ISSN	1873-2534 ; 0165-2427
ISSN (online)	1873-2534
ISSN	0165-2427
DOI	10.1016/j.vetimm.2024.110753
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Article ; Online: Stereodivergent Assembly of 2,6-

Masiuk, Uladzimir S / Faletrov, Yaroslav V / Kananovich, Dzmitry G / Mineyeva, Iryna V

The Journal of organic chemistry

2022 Volume 88, Issue 1, Page(s) 355–370

Abstract: The stereodivergent synthesis ... ...

Abstract	The stereodivergent synthesis of
MeSH term(s)	Molecular Structure ; Cyclization ; Stereoisomerism ; Organometallic Compounds
Chemical Substances	phenyllithium ; Organometallic Compounds
Language	English
Publishing date	2022-12-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	123490-0
ISSN	1520-6904 ; 0022-3263
ISSN (online)	1520-6904
ISSN	0022-3263
DOI	10.1021/acs.joc.2c02382
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Article: The enzyme activity dynamic relationship with the content of structural polypeptides of enterocyte membranes in cattle fetal

D. M. Masiuk

Ukrainian journal of veterinary and agricultural sciences. 2021 June, v. 4, no. 2

2021

Abstract: ... enzyme activity at different poles of the enterocytes plasmolemma of cow's fetal large intestine with the content ...

Abstract	The article performs new data on the relationship between the hydrolytic and transport enzyme activity at different poles of the enterocytes plasmolemma of cow's fetal large intestine with the content of individual fractions of polypeptides. An expressive direct dependence of enzyme activity dynamics on the apical and basolateral membranes of enterocytes containing low molecular weight proteins and an inverse relationship with the concentration of proteins with medium and large molecular weights has been proved. It was found that the alkaline activity of the phosphatase and γ-glutamyltransferase on the apical domain of enterocyte plasmolemma is directly related to the proteins content with molecular masses of 9.6–14.2 kD, 21 kD, 22.5 kD, 26 kD, 33 kD, 35 kD, 170–185 kD, and 205 kD (P ≤ 0.05–0.001). Gamma-glutamyltransferase activity is straightly related to protein quantity with molecular weights of 15.5 kDa and 39 kD (P ≤ 0.05). In contrast, alkaline phosphatase and GGT activity have inverse correlations with the content of polypeptides with molecular masses of 46 kD, 63 kD, and 250 kD in the apical membrane of enterocytes (P ≤ 0.01–0.001). The lactase activity in the cattle enterocytes apical membrane during the test period has significant direct correlations only with the amount of the polypeptide of polypeptides with molecular weights of 31 kD, 39 kD, and 100 kD (P ≤ 0.05–0.01) and inverse relationships containing proteins with molecular masses of 46 kD and 120 kD (P ≤ 0.05). A linear dependence of the different ATPase activity of the apical membrane of red blood cells containing proteins with molecular weights of 9.6–14.2 kD, 15.5 kD, 21 kD, 22.5 kD, 33 kD, 35 kD, 39 kD, and 205 kD (P ≤ 0.05–0.001) was observed. Alkaline phosphatase activity in the apical membrane of enterocytes is only directly related to the number of proteins with molecular weights of 17 kD and 24 kD (P ≤ 0.001) in this domain. It inversely depends on the content of proteins with molecular masses of 9.6–14.2 kD and 52 kD (P ≤ 0.001). G-glutamyltransferase activity is inversely related to protein content with molecular weights of 43 kD, 52 kD, 66 kD, 87 kD, and 100 kD and 155 kD (P ≤ 0.001). The Ca2+, Mg2+-ATPase of the basolateral membrane activity of enterocytes is directly related to the protein amount with molecular weights of 26 kD (P ≤ 0.01), Mg2+-ATPase and Mg2+-ATPase with protein content with the molecular value of 100 kD (P ≤ 0.05).
Keywords	adenosinetriphosphatase ; alkaline phosphatase ; beta-galactosidase ; calcium ; cows ; enterocytes ; enzyme activity ; gamma-glutamyltransferase ; large intestine ; molecular weight ; polypeptides ; protein content
Language	English
Dates of publication	2021-06
Size	p. 3-6.
Publishing place	Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv
Document type	Article
ISSN	2617-6149
DOI	10.32718/ujvas4-2.01
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: RECONSTRUCTION OF THE RADIOACTIVE CONTAMINATION OF THE TERRITORY OF UKRAINE BY IODINE-131 DURING INITIAL PERIOD OF THE CHORNOBYL ACCIDENT USING THE RESULTS FROM NUMERICAL MODEL WRF.

Talerko, M M / Lev, T D / Drozdovitch, V V / Masiuk, S V

Problemy radiatsiinoi medytsyny ta radiobiolohii

2020 Volume 25, Page(s) 285–299

Abstract: Objective: To reconstruct the 131I activity concentrations in air and 131I ground deposition densities from 26 April to7 May 1986 from the radioactivity release after the Chornobyl accident in the settlements of Ukraine using themesoscale radionuclides ... ...

Title translation	REKONSTRUKTsIIa RADIOAKTYVNOGO ZABRUDNENNIa TERYTORIÏ UKRAÏNY ĬODOM-131 V POChATKOVYĬ PERIOD ChORNOBYL'S'KOÏ AVARIÏ Z VYKORYSTANNIaM ChYSEL'NOÏ MODELI WRF.
Abstract	Objective: To reconstruct the 131I activity concentrations in air and 131I ground deposition densities from 26 April to7 May 1986 from the radioactivity release after the Chornobyl accident in the settlements of Ukraine using themesoscale radionuclides atmospheric transport model LEDI and meteorological information from the numericalweather forecast model WRF and to compare the obtained results with those calculated previously as well as withavailable measurements of 131I activity in soil.Object of research: the near-ground layer of the atmosphere and the surface of the territory of Ukraine radioactively contaminated as a result of the Chornobyl accident.Materials and methods of research. The dispersion of 131I in the atmosphere and deposition on the ground surfacein Ukraine were calculated using the Lagrangian-Eulerian diffusion model LEDI. The detailed fields of meteorological parameters calculated using the mesoscale weather forecast model WRF, which was adapted for the territory ofUkraine, were used as input data for the LEDI model. Results: The 131I daily-average activity concentrations in the surface air and 131I daily ground deposition densitiesfrom 26 April to 7 May 1986 were calculated using the up-to-date mesoscale model of numerical weather forecastWRF for 30,352 settlements in entire Ukraine, including 1,263 settlements in Kyiv, 1,717 - in Zhytomyr and 1,570 -in Chernihiv Oblasts. Conclusions: The method of mathematical modeling of the atmospheric transport of the radionuclides is combination with the up-to-date mesoscale model of numerical weather forecast WRF is a useful tool for reconstruction ofradioactive contamination of the air and the ground surface after the Chornobyl accident. Calculated in this study131I activity concentrations in air and 131I ground deposition densities were used to reconstruct the thyroid doses dueto 131I intake to the population of Ukraine.
MeSH term(s)	Air Pollutants, Radioactive/analysis ; Chernobyl Nuclear Accident ; Food Contamination, Radioactive/analysis ; Humans ; Iodine Radioisotopes/analysis ; Models, Statistical ; Radiation Dosage ; Radiation Exposure/analysis ; Radiation Monitoring/methods ; Radiation, Ionizing ; Radioactive Fallout/analysis ; Rural Population ; Soil Pollutants, Radioactive/analysis ; Ukraine ; Weather
Chemical Substances	Air Pollutants, Radioactive ; Iodine Radioisotopes ; Iodine-131 ; Radioactive Fallout ; Soil Pollutants, Radioactive
Language	Ukrainian
Publishing date	2020-12-28
Publishing country	Ukraine
Document type	Journal Article
ISSN	2313-4607
ISSN (online)	2313-4607
DOI	10.33145/2304-8336-2020-25-285-299
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Article ; Online: SOME ISSUES OF LIFE ACTIVITIES OF POPULATION IN THE CHORNOBYL EXCLUSION ZONE IN UKRAINE.

Gunko, N V / Ivanova, O M / Loganovsky, K M / Korotkova, N V / Masiuk, S V

Problemy radiatsiinoi medytsyny ta radiobiolohii

2021 Volume 26, Page(s) 141–161

Abstract: Background: Radiation accidents at the Chornobyl Nuclear Power Plant (USSR, 1986) and Fukushima-1 (Japan,2011) have shown that global environmental contamination is an intervention in normal human life making nega-tive effect on population health. These ...

Title translation	DEIaKI ASPEKTY ZhYTTIeDIIaL'NOSTI NASELENNIa V ChORNOBYL'S'KIĬ ZONI VIDChUZhENNIa UKRAÏNY.
Abstract	Background: Radiation accidents at the Chornobyl Nuclear Power Plant (USSR, 1986) and Fukushima-1 (Japan,2011) have shown that global environmental contamination is an intervention in normal human life making nega-tive effect on population health. These accidents highlighted a number of statutory and regulatory both with me-dical and social problems for individuals, who returned voluntarily for permanent residence in the ChornobylExclusion Zone i.e. a radiation-hazardous area (they are named the «self-settlers»). Objective: generalization of experience in the settlement of normative-legal, ecological-dosimetric and medico-social life issues of population living in the Chornobyl NPP (ChNPP) Exclusion Zone («self-settlers»). Object and methods: The chosen problem is complex, necessitating the generalization of radiation-hygienic, med-ical-biological, socio-economic, demographic and sociological research results obtained by the national and foreignauthors. A set of theoretical research and analysis of empirical data methods on the principles of interdisciplinaryinteraction was used; the systematic, legal, economic, medical-biological, demographic and retrospective-dosimet-ric approaches of research were applied. Results: It was shown that a part of population refused to evacuate or had returned for permanent residence to theradiation-hazardous lands after the ChNPP accident. In 1986-2009 the number of «self-settlers» ranged from 150to 2,000 in different years. In 2021 - the 101 people. Those were mainly people of working age, mostly females, single people or widows/widowers. Рrevious medical and dosimetric studies have shown that long-term residence inthe Exclusion Zone affects physical and mental health of «self-settlers» and causes atypical aging, includinginvolvement of the central nervous system. According to calculations, the average effective total radiation doseaccumulated by «self-settlers» for the first 3 years was 30 % of dose for the entire post-accident period, and thedose accumulated over 20 years was 54 % of the dose accumulated over 35 years. But the effective radiation dosesaccumulated in different periods after the accident differ significantly in residents of different Exclusion Zone settlements. This information needs further study in terms of the «radiation dose - health status» dependence. Conclusions: The effective radiation doses accumulated in different periods after the accident differ significantlyin the residents of different Exclusion Zone settlements. Тhe average effective total radiation dose accumulated by«self-settlers» for the first 3 years was 30 % of the dose for the entire post-accident period, and the dose accumulated over 20 years was 54 % of the dose accumulated over 35 years.
MeSH term(s)	Activities of Daily Living/psychology ; Adult ; Aged ; Aged, 80 and over ; Chernobyl Nuclear Accident ; Emigration and Immigration/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Quality of Life/psychology ; Radiation Exposure/adverse effects ; Radiation Injuries/epidemiology ; Radiation Injuries/etiology ; Radiation Monitoring/methods ; Radioactive Hazard Release/statistics & numerical data ; Retrospective Studies ; Ukraine/epidemiology
Language	Ukrainian
Publishing date	2021-12-26
Publishing country	Ukraine
Document type	Journal Article
ISSN	2313-4607
ISSN (online)	2313-4607
DOI	10.33145/2304-8336-2021-26-141-161
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Article ; Online: Assessment of Uncertainties and Errors in Post-Chernobyl Dosimetry.

Drozdovitch, Vladimir / Masiuk, Sergii / Kryuchkov, Victor / Minenko, Victor / Chizhov, Konstantin / Chepurny, Mykola / Kukhta, Tatiana / Golovanov, Ivan / Bakhanova, Elena / Chumak, Vadim

Radiation research

2023 Volume 199, Issue 5, Page(s) 517–531

Abstract: The present paper reviews the uncertainties and errors in complex dosimetry systems that were developed to estimate individual doses in different post-Chernobyl (Chornobyl) radiation epidemiology studies among the general population and the cleanup ... ...

Abstract	The present paper reviews the uncertainties and errors in complex dosimetry systems that were developed to estimate individual doses in different post-Chernobyl (Chornobyl) radiation epidemiology studies among the general population and the cleanup workers. These uncertainties and errors are associated with (i) instrumental radiation measurements of humans and environmental samples, (ii) inherent uncertainties arising from the stochastic random variability of the parameters used in exposure assessment and from a lack of knowledge about the true values of the parameters, and (iii) human factor uncertainties due to poor memory recall resulting in incomplete, inaccurate, or missing responses during personal interview with study subjects conducted long after exposure. Relative measurement errors of 131I thyroid activity associated with devices for measuring radioactivity in the thyroid reached up to 0.86 (coefficient of variation). The inherent uncertainty in estimates of individual doses varied between different studies and exposure pathways (GSD from 1.2 to 15 for model-based doses and from 1.3 to 5.1 for measurement-based doses). The human factor uncertainties can cause individual doses to be underestimated or overestimated by an average of 10 times for model-based doses and 2 times for measurement-based doses calculated for the general population and up to 3 times for doses calculated for cleanup workers. The sources of errors and uncertainties, especially the human factor uncertainties, should be carefully considered in dose assessment for radiation epidemiological studies, with particular attention to studies involving persons without instrumental radiation measurements.
MeSH term(s)	Humans ; Radiation Dosage ; Chernobyl Nuclear Accident ; Iodine Radioisotopes ; Uncertainty ; Risk Assessment/methods
Chemical Substances	Iodine-131 ; Iodine Radioisotopes
Language	English
Publishing date	2023-03-07
Publishing country	United States
Document type	Review ; Journal Article ; Research Support, N.I.H., Intramural
ZDB-ID	80322-4
ISSN	1938-5404 ; 0033-7587
ISSN (online)	1938-5404
ISSN	0033-7587
DOI	10.1667/RADE-22-00138.1
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Article ; Online: ON THE METHODOLOGY OF PASSPORT DOSES CALCULATION FOR UKRAINIAN SETTLEMENTS RADIOACTIVELY CONTAMINATED DUE TO THE CHORNOBYL NPP ACCIDENT.

Bazyka, D A / Sushko, V O / Ivanova, O M / Vasylenko, V V / Bilonyk, A B / Fedosenko, G V / Buderatska, V B / Boiko, Z N / Chepurny, M I / Kuriata, M S / Morozov, V V / Gorbachov, S G / Masiuk, S V

Problemy radiatsiinoi medytsyny ta radiobiolohii

2023 Volume 28, Page(s) 110–142

Abstract: Objective: scientific substantiation of the new methodology for estimation of passport doses of the settlementswhich belong to Zone of Unconditional (obligatory) Resettlement, or 2nd zone and Zone of Granted VoluntaryResettlement, or 3rd zone in the ... ...

Title translation	ЩОДО МЕТОДИКИ РОЗРАХУНКУ ПАСПОРТНИХ ДОЗ НАСЕЛЕНИХ ПУНКТІВ УКРАЇНИ, ЯКІ ЗАЗНАЛИ РАДІОАКТИВНОГО ЗАБРУДНЕННЯ В РЕЗУЛЬТАТІ АВАРІЇ НА ЧАЕС.
Abstract	Objective: scientific substantiation of the new methodology for estimation of passport doses of the settlementswhich belong to Zone of Unconditional (obligatory) Resettlement, or 2nd zone and Zone of Granted VoluntaryResettlement, or 3rd zone in the framework of dosimetric passportization in accordance with the legislation ofUkraine. Materials and methods: 37 years after the accident, radioactive contamination of the environment has significantly decreased. However, it is still necessary to carry out ecological and dosimetric monitoring and apply countermeasures in certain territories of Ukraine affected by the accident at the Chornobyl Nuclear Power Plant: restriction of the consumption of locally produced milk, forest products, etc. The methodology, which was since 1996 used to estimate the passport doses of Ukrainian settlements, no longer corresponds to the current level of scientific knowledge about radioactive contamination of environment. The new methods of passport doses calculating presented in the work involves the use of a model whose parameters are determined by the types, quality and completeness of radio-ecological and dosimetric monitoring carried out on the radioactively contaminated territories in 1986-2013. The methodology takes into account the specific of radioactive contamination of each settlement. The passport dose of external exposure is reconstructed only from 137Cs radionuclide, because the contributions of other Chornobyl radionuclides influence the radiation dose only in the first years after the accident. The passport dose of internal exposure is formed as a result of the consumption of 137Cs contaminated food products. It is calculated depending on the availability in the settlement in the current year of the results of measurements of the 137Cs radionuclide activity incorporated in the human body using a whole body counter (WBC) and the activity of 137Cs in the private milk. At the same time, priority is given precisely to the results of WBC measurements of 137Cs. Results and conclusions: A new methodology (Methodology-2023) for passport doses calculation of Ukrainian settlements was substantiated. A comparison of passport doses based on the results of radioecological and dosimetric monitoring in 2011 calculated by Methodology-2023 and passport doses calculated by Methodology-96 was made.Passport doses calculated by Methodology-2023 increased by 40 % on average compared to doses calculated by Methodology-96. At the same time, passport doses of internal radiation calculated by the new methodologyincreased by 1.5 times, and passport doses of external radiation increased by 1.7 times. The passport dose of 2011, calculated by Methodology-2023, exceeds the legally established limit of 1 mSv in 71 settlements, most of which are located in Korostenkyi raion of Zhytomyr Oblast.
MeSH term(s)	Humans ; Radiation Dosage ; Cesium Radioisotopes/analysis ; Chernobyl Nuclear Accident ; Body Burden ; Food Contamination, Radioactive/analysis ; Ukraine ; Radiation Monitoring/methods
Chemical Substances	Cesium-137 (4T2E65IAR7) ; Cesium Radioisotopes
Language	Ukrainian
Publishing date	2023-12-28
Publishing country	Ukraine
Document type	Journal Article
ISSN	2313-4607
ISSN (online)	2313-4607
DOI	10.33145/2304-8336-2023-28-110-142
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Article: METHODOLOGY OF RECONSTRUCTION OF INDIVIDUALIZED EXPOSURE DOSES FOR PERSONS RESIDING AT RADIOACTIVELY CONTAMINATED TERRITORIES OF UKRAINE.

Ivanova, O M / Kovgan, L M / Masiuk, S V

Problemy radiatsiinoi medytsyny ta radiobiolohii

2018 Volume 23, Page(s) 164–187

Abstract: Objective: Development of methodology for reconstruction of individualized exposure doses for persons residing atradioactively contaminated after Chornobyl accident territories.Materials and methods of research. The methodology is based on the data of ... ...

Title translation	METODYKA REKONSTRUKTsIÏ INDYVIDUALIZOVANYKh DOZ OPROMINENNIa OSIB, ShchO MEShKAIuT' NA RADIOAKTYVNO ZABRUDNENYKh TERYTORIIaKh UKRAÏNY.
Abstract	Objective: Development of methodology for reconstruction of individualized exposure doses for persons residing atradioactively contaminated after Chornobyl accident territories.Materials and methods of research. The methodology is based on the data of radio-ecological (ground, meal) anddosimetric (WBC measurements) monitoring held in Ukraine in 1986-2013, the results of which are saved in databases of Central Ecological and Dosimetric Register of Radiation Protection Laboratory of NRCRM. It is presentedfour levels of individualization of exposure doses. Each subsequent level of the model is based on the previous oneand takes into account additional parameters, and as a result a model of the next level comprises more number ofexposure situations and provides more accurate estimates. Using the methodology it is necessary to select a modelof such level that enables to solve in the best way the assignments posed before a researcher. For the population ofradioactively contaminated territories, two main ways of exposure are considered: (a) external gamma-exposurefrom radionuclides in the ground, and (b) internal exposure from consumption of radioactively contaminated meal.The dose is evaluated from all the main radionuclides of radioactive accident deposition, and in case of internalexposure after 1986 - only from radio-isotopes of cesium (134Cs and 137Cs). Results: Individualized doses are evaluated for different age groups of population residing in 10 raions of the mostcontaminated after Chornobyl accident Oblasts of Ukraine: Zhytomyr, Kyiv, Rivne and Chernihiv Oblasts. Dose esti-mates are presented weighted by the number of residents in settlements of specific raions. Among them are: thedose for 1986, doses accumulated during the first 15 years after the accident (1986-2000), and during the periodof 32 years after the accident (1986-2017). Conclusions: Average raion dose reconstructed for adult residents of the most radioactively contaminatedNarodychy Raion of Zhytomyr Oblast in 1986 was 18 mSv, and accumulated during the whole period after the acci-dent was 51 mSv. The lowest doses among abovementioned 10 raions were obtained by persons residing at the ter-ritory of Kozelets and Ripky Raions of Chernihiv Oblast. Average dose for them in 1986 constituted 1.3 and 1.7 mSv,and the one accumulated during 32 years was 6.1 and 6.2, respectively.
MeSH term(s)	Adolescent ; Adult ; Aged ; Animals ; Body Burden ; Cesium Radioisotopes/analysis ; Chernobyl Nuclear Accident ; Child ; Child, Preschool ; Databases, Factual ; Environmental Exposure/analysis ; Female ; Food Contamination, Radioactive/analysis ; Gamma Rays/adverse effects ; Humans ; Infant ; Longitudinal Studies ; Male ; Middle Aged ; Models, Statistical ; Radiation Dosage ; Radiation Exposure/analysis ; Radiation Monitoring/methods ; Radiation Monitoring/statistics & numerical data ; Risk Assessment ; Ukraine
Chemical Substances	Cesium Radioisotopes
Language	Ukrainian
Publishing date	2018-10-19
Publishing country	Ukraine
Document type	Journal Article
ISSN	2304-8336
ISSN	2304-8336
DOI	10.33145/2304-8336-2018-23-164-187
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Article: Radiation Risk Analysis of Neuropsychiatric Disorders in Ukrainian Chornobyl Catastrophe Liquidators.

Loganovsky, Konstantyn N / Masiuk, Sergii V / Buzunov, Vladimir A / Marazziti, Donatella / Voychulene, Yuliya S

Frontiers in psychiatry

2020 Volume 11, Page(s) 553420

Abstract: Goal: ...

Abstract	Goal:
Language	English
Publishing date	2020-11-17
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2020.553420
Database	MEDical Literature Analysis and Retrieval System OnLINE

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