LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 210

Search options

  1. Article: Interview with Scott B. Halstead, M.D.

    Halstead, Scott B

    Vector borne and zoonotic diseases (Larchmont, N.Y.)

    2007  Volume 7, Issue 1, Page(s) 99–105

    MeSH term(s) Aedes/virology ; Animals ; Dengue/prevention & control ; Dengue Vaccines/immunology ; Global Health ; Humans ; Mosquito Control ; Public Health
    Chemical Substances Dengue Vaccines
    Language English
    Publishing date 2007
    Publishing country United States
    Document type Interview
    ZDB-ID 2047199-3
    ISSN 1557-7759 ; 1530-3667
    ISSN (online) 1557-7759
    ISSN 1530-3667
    DOI 10.1089/vbz.2007.9998
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6137: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Three Dengue Vaccines - What Now?

    Halstead, Scott B

    The New England journal of medicine

    2024  Volume 390, Issue 5, Page(s) 464–465

    MeSH term(s) Humans ; Dengue/prevention & control ; Dengue Vaccines/adverse effects ; Dengue Vaccines/therapeutic use ; Dengue Virus ; Vaccines, Attenuated/adverse effects ; Vaccines, Attenuated/therapeutic use
    Chemical Substances Dengue Vaccines ; Vaccines, Attenuated
    Language English
    Publishing date 2024-02-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMe2314240
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.34: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Is Dengue Vaccine Protection Possible?

    Halstead, Scott B

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2021  Volume 74, Issue 1, Page(s) 156–160

    Abstract: In tropical and subtropical countries, 4 dengue viruses (DENVs) produce mild disease and a potentially fatal vascular permeability syndrome. Unique antigenic and biological properties of DENVs contribute to vaccine development delays. Three tissue ... ...

    Abstract In tropical and subtropical countries, 4 dengue viruses (DENVs) produce mild disease and a potentially fatal vascular permeability syndrome. Unique antigenic and biological properties of DENVs contribute to vaccine development delays. Three tissue culture-based tetravalent candidate dengue vaccines have advanced to phase 3 clinical testing. Sanofi-Pasteur's chimeric yellow fever tetravalent dengue vaccine, Dengvaxia, licensed in 19 dengue-endemic countries, Europe, and the United States, partially protects seropositives but sensitizes some seronegatives to severe hospitalized dengue. During 2 years of phase 3, Takeda's TAK-003, a chimeric DENV 2 tetravalent vaccine, protected against DENV 2 but was less protective against other DENVs. In seronegative adults, 1 dose of a tetravalent nonstructural deletion mutant vaccine in late phase developed by the US National Institutes of Health protected seronegative humans against challenge with DENVs 2 and 3. This experience suggests nearly whole DENV genomes are required to achieve balanced and sustained protective immunity.
    MeSH term(s) Adult ; Antibodies, Neutralizing ; Antibodies, Viral ; Dengue/prevention & control ; Dengue Vaccines ; Dengue Virus ; Humans ; Vaccines, Attenuated ; Yellow Fever
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral ; Dengue Vaccines ; Vaccines, Attenuated
    Language English
    Publishing date 2021-03-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciab282
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1505: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 480: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Vaccine-Associated Enhanced Viral Disease: Implications for Viral Vaccine Development.

    Halstead, Scott B

    BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy

    2021  Volume 35, Issue 5, Page(s) 505–515

    Abstract: Vaccine-associated enhanced disease (VAED) is a serious barrier to attaining successful virus vaccines in human and veterinary medicine. VAED occurs as two different immunopathologies, antibody-dependent enhancement (ADE) and vaccine-associated ... ...

    Abstract Vaccine-associated enhanced disease (VAED) is a serious barrier to attaining successful virus vaccines in human and veterinary medicine. VAED occurs as two different immunopathologies, antibody-dependent enhancement (ADE) and vaccine-associated hypersensitivity (VAH). ADE contributes to the pathology of disease caused by four dengue viruses (DENV) through control of the intensity of cellular infection. Products of virus-infected cells are toxic. A partially protective yellow fever chimeric tetravalent DENV vaccine sensitized seronegative children to ADE breakthrough infections. A live-attenuated tetravalent whole virus vaccine in phase III testing appears to avoid ADE by providing durable protection against the four DENV. VAH sensitization by viral vaccines occurred historically. Children given formalin-inactivated measles or respiratory syncytial virus (RSV) vaccines experienced severe disease during breakthrough infections. Tissue responses demonstrated that VAH not ADE caused these vaccine safety problems. Subsequently, measles was successfully and safely contained by a live-attenuated virus vaccine. The difficulty in formulating a safe and effective RSV vaccine is troublesome evidence that avoiding VAH is a major research challenge. VAH-like tissue responses were observed during breakthrough homologous virus infections in monkeys given severe acute respiratory syndrome (SARS) or Middle East respiratory syndrome (MERS) vaccines.
    MeSH term(s) Antibodies, Neutralizing ; Antibodies, Viral ; Dengue ; Dengue Vaccines ; Humans ; Viral Envelope Proteins ; Virus Diseases
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral ; Dengue Vaccines ; Viral Envelope Proteins
    Language English
    Publishing date 2021-09-09
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 1364202-9
    ISSN 1179-190X ; 1173-8804
    ISSN (online) 1179-190X
    ISSN 1173-8804
    DOI 10.1007/s40259-021-00495-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4112: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: A Step in the Right Direction.

    Halstead, Scott B

    The Journal of infectious diseases

    2020  Volume 222, Issue 5, Page(s) 712–714

    MeSH term(s) Antibody-Dependent Enhancement ; Child ; Dengue ; Humans ; Viral Load ; Virus Diseases
    Language English
    Publishing date 2020-05-11
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3019-3
    ISSN 1537-6613 ; 0022-1899
    ISSN (online) 1537-6613
    ISSN 0022-1899
    DOI 10.1093/infdis/jiz619
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.50: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 445: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book: Dengue

    Halstead, Scott B.

    (Tropical medicine ; 5)

    2008  

    Author's details ed. by Scott B. Halstead
    Series title Tropical medicine ; 5
    Collection
    Keywords Dengue ; Dengue Virus / pathogenicity
    Language English
    Size XX, 485 S. : Ill., graph. Darst.
    Publisher Imperial College Press
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT015751309
    ISBN 1-84816-228-6 ; 978-1-84816-228-0
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2009 A 6639 order for loan Magazin

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: COVID-19: The Need for Immunoprevention at Industrial Scale.

    Halstead, Scott B

    The American journal of tropical medicine and hygiene

    2020  Volume 102, Issue 6, Page(s) 1151

    MeSH term(s) Antibodies, Monoclonal/biosynthesis ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Monoclonal/therapeutic use ; Antiviral Agents/chemical synthesis ; Antiviral Agents/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques/statistics & numerical data ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Humans ; Immune Sera/chemistry ; Immune Sera/pharmacology ; Immunotherapy/methods ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; United States/epidemiology ; Viral Vaccines/biosynthesis ; Viral Vaccines/therapeutic use
    Chemical Substances Antibodies, Monoclonal ; Antiviral Agents ; COVID-19 Vaccines ; Immune Sera ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-04-10
    Publishing country United States
    Document type Editorial
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.20-0239
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.61: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: An Urgent Need for "Common Cold Units" to Study COVID-19.

    Halstead, Scott B

    The American journal of tropical medicine and hygiene

    2020  Volume 102, Issue 6, Page(s) 1152–1153

    MeSH term(s) Antibodies, Monoclonal/biosynthesis ; Antibodies, Monoclonal/isolation & purification ; Antibodies, Monoclonal/therapeutic use ; Antiviral Agents/chemical synthesis ; Antiviral Agents/therapeutic use ; Betacoronavirus/drug effects ; Betacoronavirus/pathogenicity ; COVID-19 ; COVID-19 Testing ; COVID-19 Vaccines ; Clinical Laboratory Techniques/statistics & numerical data ; Common Cold/diagnosis ; Common Cold/drug therapy ; Common Cold/epidemiology ; Common Cold/prevention & control ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Drug Repositioning/statistics & numerical data ; Humans ; Immune Sera/chemistry ; Immune Sera/pharmacology ; Immunotherapy/methods ; International Cooperation ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; SARS-CoV-2 ; United States/epidemiology ; Viral Vaccines/biosynthesis ; Viral Vaccines/therapeutic use
    Chemical Substances Antibodies, Monoclonal ; Antiviral Agents ; COVID-19 Vaccines ; Immune Sera ; Viral Vaccines
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.20-0246
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.61: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Travelling arboviruses: A historical perspective.

    Halstead, Scott B

    Travel medicine and infectious disease

    2019  Volume 31, Page(s) 101471

    Abstract: Chikungunya, dengue, yellow fever and Zika viruses share many attributes. All are complex and widespread zoonoses of subhuman primates that have made successful transitions to the urban Aedes aegypti transmission cycle. More important, they have an ... ...

    Abstract Chikungunya, dengue, yellow fever and Zika viruses share many attributes. All are complex and widespread zoonoses of subhuman primates that have made successful transitions to the urban Aedes aegypti transmission cycle. More important, they have an established record of travelling, having moved from their place of origin hundreds of years ago, sometimes repeatedly. Understanding their epidemiology requires a knowledge of past behaviors including unexplained restraints to their travel. This is a review of mechanisms that may contribute to invasiveness and pathogenicity of these important human pathogens.
    MeSH term(s) Arbovirus Infections/epidemiology ; Arbovirus Infections/history ; Arbovirus Infections/virology ; Arboviruses/physiology ; History, 18th Century ; History, 19th Century ; History, 20th Century ; History, 21st Century ; Humans ; Travel-Related Illness
    Language English
    Publishing date 2019-08-28
    Publishing country Netherlands
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2019.101471
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6236: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Insights from direct studies on human dengue infections.

    Halstead, Scott B

    Proceedings of the National Academy of Sciences of the United States of America

    2018  Volume 116, Issue 1, Page(s) 17–19

    MeSH term(s) Dengue ; Dengue Virus ; Humans
    Language English
    Publishing date 2018-12-13
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.1819607116
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1148: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top