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  1. Article: Lodge, George C.; Wilson, Craig: A corporate solution to global poverty, how multinationals can help the poor and invigorate their own legitimacy : Princeton, NJ [u.a.], Princeton Univ. Press, 2006 / [rezensiert von:] Robert Kennedy

    Kennedy, Robert / Lodge, George C / Wilson, Craig

    Journal of economic literature Vol. 45, No. 2 , p. 432-437

    2007  Volume 45, Issue 2, Page(s) 432–437

    Language English
    Publisher Assoc.
    Publishing place Nashville, Tenn.
    Document type Article
    ZDB-ID 3076-4
    Database ECONomics Information System

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  2. Article ; Online: Reply to Robert P. Myers' letter to the editor re: Francesco Montorsi, Timothy G. Wilson, Raymond C. Rosen, et al. best practices in robot-assisted radical prostatectomy: recommendations of the Pasadena consensus panel. Eur Urol 2012;62:368-81.

    Ficarra, Vincenzo / Novara, Giacomo / Mottrie, Alexandre / Wilson, Timothy G / Montorsi, Francesco

    European urology

    2013  Volume 63, Issue 3, Page(s) e42–3

    MeSH term(s) Benchmarking/standards ; Humans ; Laparoscopy/standards ; Male ; Prostatectomy/standards ; Prostatic Neoplasms/surgery ; Robotics/standards ; Surgery, Computer-Assisted/standards
    Language English
    Publishing date 2013-03
    Publishing country Switzerland
    Document type Comment ; Letter
    ZDB-ID 193790-x
    ISSN 1873-7560 ; 1421-993X ; 0302-2838
    ISSN (online) 1873-7560 ; 1421-993X
    ISSN 0302-2838
    DOI 10.1016/j.eururo.2012.11.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1247: Show issues Location:
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    Zs.MO 294: Show issues

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  3. Article ; Online: Oxidosqualene Cyclase Residues that Promote Formation of Cycloartenol, Lanosterol, and Parkeol We are grateful to Bridget M. Joubert for advice regarding mutagenesis. We thank Elizabeth A. Hart for an authentic parkeol standard, and for chromatographic and spectroscopic information. This research was funded by the National Institutes of Health (grant no. AI 41598) and the Robert A. Welch Foundation (grant no. C-1323). M.M.M. was an American Society of Pharmacognosy Undergraduate Fellow. M.J.R.S. was a Robert A. Welch Fellow and was supported by an NIH Biotechnology Training Grant (grant no. T32 GM08362).

    Meyer / Segura / Wilson / Matsuda

    Angewandte Chemie (International ed. in English)

    2000  Volume 39, Issue 22, Page(s) 4090–4092

    Language English
    Publishing date 2000-11-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/1521-3773(20001117)39:22<4090::aid-anie4090>3.0.co;2-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Experimental Evidence for Millisecond-Timescale Structural Evolution Following the Microsecond-Timescale Folding of a Small Protein.

    Wilson, C Blake / Yau, Wai-Ming / Tycko, Robert

    Physical review letters

    2024  Volume 132, Issue 4, Page(s) 48402

    Abstract: ... process that has not been previously detected. ^{13}C ssNMR spectra of frozen HP35 solutions, acquired ... with a variable time τ_{e} at 30 °C after rapid cooling from 95 °C and before rapid freezing, show changes ...

    Abstract Prior work has shown that small proteins can fold (i.e., convert from unstructured to structured states) within 10  μs. Here we use time-resolved solid state nuclear magnetic resonance (ssNMR) methods to show that full folding of the 35-residue villin headpiece subdomain (HP35) requires a slow annealing process that has not been previously detected. ^{13}C ssNMR spectra of frozen HP35 solutions, acquired with a variable time τ_{e} at 30 °C after rapid cooling from 95 °C and before rapid freezing, show changes on the 3-10 ms timescale, attributable to slow rearrangements of protein sidechains during τ_{e}.
    MeSH term(s) Protein Folding ; Magnetic Resonance Spectroscopy
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.132.048402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Millisecond Time-Resolved Solid-State NMR Initiated by Rapid Inverse Temperature Jumps.

    Wilson, C Blake / Tycko, Robert

    Journal of the American Chemical Society

    2022  Volume 144, Issue 22, Page(s) 9920–9925

    Abstract: ... and cooled blocks, solution temperatures can be switched from 95 to 30 °C (or lower) in about 0.8 ms ...

    Abstract Elucidation of the detailed mechanisms by which biological macromolecules undergo major structural conversions, such as folding, complex formation, and self-assembly, is a central concern of biophysical chemistry that will benefit from new experimental methods. We describe a simple technique for initiating a structural conversion process by a rapid decrease in the temperature of a solution, i.e., a rapid inverse temperature jump. By pumping solutions through copper capillary tubes that are thermally anchored to heated and cooled blocks, solution temperatures can be switched from 95 to 30 °C (or lower) in about 0.8 ms. For time-resolved solid-state nuclear magnetic resonance (ssNMR), solutions can then be frozen rapidly by spraying into cold isopentane after a variable structural evolution time τ
    MeSH term(s) Kinetics ; Magnetic Resonance Spectroscopy/methods ; Melitten/chemistry ; Protein Conformation, alpha-Helical ; Temperature
    Chemical Substances Melitten (20449-79-0)
    Language English
    Publishing date 2022-05-26
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 3155-0
    ISSN 1520-5126 ; 0002-7863
    ISSN (online) 1520-5126
    ISSN 0002-7863
    DOI 10.1021/jacs.2c02704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online: (Table S1) Chronostratigraphic constrains for sediment core AND1-1B, supplementary data to: Naish, Tim R; Powell, Ross; Levy, R; Wilson, Gary S; Scherer, Reed P; Talarico, Franco; Krissek, Lawrence A; Niessen, Frank; Pompilio, Massimo; Wilson, Terry; Carter, Lionel; DeConto, Robert M; Huybers, P; McKay, R; Pollard, David; Ross, J; Winter, Diane M; Barrett, Peter J; Browne, G; Cody, R; Cowan, Ellen A; Crampton, J; Dunbar, Gavin B; Dunbar, N; Florindo, Fabio; Gebhardt, Andrea Catalina; Graham, IJ; Hannah, Mike J; Hansaraj, D; Harwood, David M; Helling, D; Henrys, Stuart; Hinnov, L; Kuhn, Gerhard; Kyle, Philip R; Läufer, Andreas L; Maffioli, P; Magens, Diana; Mandernack, Kevin W; McIntosh, WC; Millan, C; Morin, Roger H; Ohneiser, Christian; Paulsen, Timothy S; Persico, Davide; Raine, J Ian; Reed, J; Riesselman, C; Sagnotti, Leo; Schmitt, D R; Sjunneskog, C; Strong, P; Taviani, Marco; Vogel, Stefan; Wilch, T; Williams, Trevor (2009): Obliquity-paced Pliocene West Antarctic ice sheet oscillations. Nature, 458(7236), 322-329

    Naish, Tim R / Krissek, Lawrence A / Levy, R / Niessen, Frank / Pompilio, Massimo / Powell, Ross / Scherer, Reed P / Talarico, Franco / Wilson, Gary S / al., et

    2009  

    Abstract: ... when planetary temperatures were up to ~3° C warmer than today ( Kim and Crowley, 2000, doi:10.1029/1999PA000459 ...

    Abstract Thirty years after oxygen isotope records from microfossils deposited in ocean sediments confirmed the hypothesis that variations in the Earth's orbital geometry control the ice ages (Hays et al., 1976, doi:10.1126/science.194.4270.1121), fundamental questions remain over the response of the Antarctic ice sheets to orbital cycles (Raymo and Huybers, 2008, doi:10.1038/nature06589). Furthermore, an understanding of the behaviour of the marine-based West Antarctic ice sheet (WAIS) during the 'warmer-than-present' early-Pliocene epoch (~5-3 Myr ago) is needed to better constrain the possible range of ice-sheet behaviour in the context of future global warming (Solomon et al., 2007). Here we present a marine glacial record from the upper 600 m of the AND-1B sediment core recovered from beneath the northwest part of the Ross ice shelf by the ANDRILL programme and demonstrate well-dated, ~40-kyr cyclic variations in ice-sheet extent linked to cycles in insolation influenced by changes in the Earth's axial tilt (obliquity) during the Pliocene. Our data provide direct evidence for orbitally induced oscillations in the WAIS, which periodically collapsed, resulting in a switch from grounded ice, or ice shelves, to open waters in the Ross embayment when planetary temperatures were up to ~3° C warmer than today ( Kim and Crowley, 2000, doi:10.1029/1999PA000459) and atmospheric CO2 concentration was as high as ~400 p.p.m.v. (van der Burgh et al., 1993, doi:10.1126/science.260.5115.1788, Raymo et al., 1996, doi:10.1016/0377-8398(95)00048-8). The evidence is consistent with a new ice-sheet/ice-shelf model (Pollard and DeConto, 2009, doi:10.1038/nature07809) that simulates fluctuations in Antarctic ice volume of up to +7 m in equivalent sea level associated with the loss of the WAIS and up to +3 m in equivalent sea level from the East Antarctic ice sheet, in response to ocean-induced melting paced by obliquity. During interglacial times, diatomaceous sediments indicate high surface-water productivity, minimal summer sea ice and air temperatures above freezing, suggesting an additional influence of surface melt (Huybers, 2006, doi:10.1126/science.1125249) under conditions of elevated CO2.
    Language English
    Dates of publication 2009-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1038/nature07867
    DOI 10.1594/PANGAEA.769658
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Article ; Online: Epigenetic-related transcriptional reprogramming elucidated by identification and validation of a novel reference gene combination for RT-qPCR studies in porcine oocytes of contrasting quality.

    Haug, Linda Marijke / Wilson, Robert C / Alm-Kristiansen, Anne Hege

    Molecular biology reports

    2024  Volume 51, Issue 1, Page(s) 368

    Abstract: Background: Reliable RT-qPCR results are dependent on appropriate normalisation. Oocyte maturation studies can be challenging in this respect, as the stage of development can distinctively affect reference gene transcript abundance. The aim of this ... ...

    Abstract Background: Reliable RT-qPCR results are dependent on appropriate normalisation. Oocyte maturation studies can be challenging in this respect, as the stage of development can distinctively affect reference gene transcript abundance. The aim of this study was to validate the use of reference genes in oocyte in vitro maturation RT-qPCR studies, and thereafter, examine the abundance of transcripts supporting histone modification during oocyte and early embryo development in oocytes of contrasting quality.
    Methods and results: Total RNA from oocytes from prepubertal gilts and sows was extracted either directly succeeding follicle aspiration or after 44 h in vitro maturation, followed by RT-qPCR. The stability of YWHAG, HPRT1, ACTB, GAPDH, HMBS and PFKP, was analysed by NormFinder and further cross-validated by assessing results generated following application of different combinations of potential reference genes for normalisation of the RT-qPCR data. Combining ACTB and PFKP generated high stability according to NormFinder and concordant results. Applying this normalisation, gilt derived oocytes displayed significantly higher abundance than oocytes from sows of almost all the epigenetic-related transcripts studied (HDAC2, SIRT1, SALL4, KDM1A, KDM1B, KDM5A), both before and after maturation.
    Conclusions: This study identified the combined use of ACTB and PFKP as the optimal normalisation for porcine oocyte RT-qPCR data. In oocytes collected from prepubertal gilts, transcription did not appear to be silenced at the time of aspiration, and accumulation of transcripts supporting histone modification facilitating proper fertilization and further embryo development seemed delayed. The results imply the epigenetic-related transcripts may have potential as markers of oocyte quality.
    MeSH term(s) Swine/genetics ; Animals ; Female ; Oocytes ; Sus scrofa ; In Vitro Oocyte Maturation Techniques ; Embryonic Development ; Epigenesis, Genetic
    Language English
    Publishing date 2024-02-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 186544-4
    ISSN 1573-4978 ; 0301-4851
    ISSN (online) 1573-4978
    ISSN 0301-4851
    DOI 10.1007/s11033-024-09319-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1140: Show issues Location:
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  8. Book ; Online: Sedimentology, geochemistry and paleomagnetic of ODP Hole 151-913B, supplementary data to: Eldrett, James S; Harding, Ian C; Wilson, Paul A; Butler, Emily; Roberts, Andrew P (2007): Continental ice in Greenland during the Eocene and Oligocene. Nature, 446(7132), 176-179

    Eldrett, James S / Butler, Emily / Harding, Ian C / Roberts, Andrew P / Wilson, Paul A

    2007  

    Abstract: The Eocene and Oligocene epochs (55 to 23 million years ago) comprise a critical phase in Earth history. An array of geological records (Zachos et al., 2001, doi:10.1126/science.1059412; Lear et al., 2000, doi:10.1126/science.287.5451.269; Coxall et al., ...

    Abstract The Eocene and Oligocene epochs (55 to 23 million years ago) comprise a critical phase in Earth history. An array of geological records (Zachos et al., 2001, doi:10.1126/science.1059412; Lear et al., 2000, doi:10.1126/science.287.5451.269; Coxall et al., 2005, doi:10.1038/nature03135; Pekar et al., 2005; doi:10.1130/B25486.1; Strand et al., 2003, doi:10.1016/S0031-0182(03)00396-1) supported by climate modelling (DeConto and Pollard, 2003, doi:10.1038/nature01290) indicates a profound shift in global climate during this interval, from a state that was largely free of polar ice caps to one in which ice sheets on Antarctica approached their modern size. However, the early glaciation history of the Northern Hemisphere is a subject of controversy (Coxall et al., 2005, doi:10.1038/nature03135; Tripati et al., 2005, doi:10.1038/nature03874; Wolf-Welling et al., 1996, doi:10.2973/odp.proc.sr.151.139.1996; Moran et al., 2006, doi:10.1038/nature04800). Here we report stratigraphically extensive ice-rafted debris, including macroscopic dropstones, in late Eocene to early Oligocene sediments from the Norwegian-Greenland Sea that were deposited between about 38 and 30?million years ago. Our data indicate sediment rafting by glacial ice, rather than sea ice, and point to East Greenland as the likely source. Records of this type from one site alone cannot be used to determine the extent of ice involved. However, our data suggest the existence of (at least) isolated glaciers on Greenland about 20?million years earlier than previously documented (Winkler et al., 2002, doi:10.1007/s005310100199), at a time when temperatures and atmospheric carbon dioxide concentrations were substantially higher.
    Language English
    Dates of publication 2007-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1038/nature05591
    DOI 10.1594/PANGAEA.769772
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Article: Editorial: Computational accounts of reinforcement learning and decision making in psychiatric disorders.

    Chase, Henry W / Wilson, Robert C / Waltz, James A

    Frontiers in psychiatry

    2022  Volume 13, Page(s) 966369

    Language English
    Publishing date 2022-07-25
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2022.966369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Author Correction: Age-group differences in trust-related decision-making and learning.

    Horta, Marilyn / Shoenfelt, Alayna / Lighthall, Nichole R / Perez, Eliany / Frazier, Ian / Heemskerk, Amber / Lin, Tian / Wilson, Robert C / Ebner, Natalie C

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5132

    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55891-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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