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  1. Article ; Online: [No title information]

    Rockstroh, J K

    Drug research

    2016  Volume 66, Issue S 01, Page(s) S15–S16

    Title translation Behandlung von HIV-Infektionen und AIDS.
    Language German
    Publishing date 2016-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/s-0042-112400
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 research: an opinion piece.

    Waters, L / Rockstroh, J K

    HIV medicine

    2020  Volume 21, Issue 8, Page(s) 536–540

    Abstract: The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel ... ...

    Abstract The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel infection outbreaks, antiretrovirals are just one drug class that has been held up as a potential strategy for prophylaxis and treatment with scant evidence and risk of harm. Here we summarize the evidence for antiretrovirals to treat COVID-19 and, as a drug that has also been studied in HIV, hydroxychloroquine, and flag some of the pitfalls of using therapies that have not been evaluated robustly.
    MeSH term(s) Anti-Retroviral Agents/therapeutic use ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/prevention & control ; Drug Combinations ; Drug Repositioning/standards ; Drug Repositioning/trends ; Humans ; Hydroxychloroquine/therapeutic use ; Lopinavir/therapeutic use ; Pandemics/prevention & control ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/prevention & control ; Research/standards ; Research/trends ; Ritonavir/therapeutic use ; SARS-CoV-2 ; Tenofovir/therapeutic use ; Time Factors
    Chemical Substances Anti-Retroviral Agents ; Drug Combinations ; lopinavir-ritonavir drug combination ; Lopinavir (2494G1JF75) ; Hydroxychloroquine (4QWG6N8QKH) ; Tenofovir (99YXE507IL) ; Ritonavir (O3J8G9O825)
    Keywords covid19
    Language English
    Publishing date 2020-07-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001932-4
    ISSN 1468-1293 ; 1464-2662
    ISSN (online) 1468-1293
    ISSN 1464-2662
    DOI 10.1111/hiv.12913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The path to hepatitis C elimination: who are we leaving behind and why?

    Rockstroh, Jurgen K / Swan, Tracy / Chang, Judy / Elamouri, Fauzi / Lloyd, Andrew R

    Journal of the International AIDS Society

    2023  Volume 26, Issue 7, Page(s) e26136

    MeSH term(s) Humans ; HIV Infections/drug therapy ; Hepatitis C/drug therapy ; Hepatitis C/epidemiology ; Hepatitis C/prevention & control ; Hepacivirus ; Antiviral Agents/therapeutic use ; Hepatitis C, Chronic/drug therapy ; Hepatitis C, Chronic/epidemiology ; Hepatitis C, Chronic/prevention & control
    Chemical Substances Antiviral Agents
    Language English
    Publishing date 2023-07-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2467110-1
    ISSN 1758-2652 ; 1758-2652
    ISSN (online) 1758-2652
    ISSN 1758-2652
    DOI 10.1002/jia2.26136
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: COVID-19 research: an opinion piece

    Waters, L / Rockstroh, J K

    HIV Med

    Abstract: The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel ... ...

    Abstract The unprecedented global scale of COVID-19 globally has triggered a race to discover interventions to reduce associated morbidity and mortality and rapid release of research findings prior to any degree of critical review. As with previous novel infection outbreaks, antiretrovirals are just one drug class that has been held up as a potential strategy for prophylaxis and treatment with scant evidence and risk of harm. Here we summarize the evidence for antiretrovirals to treat COVID-19 and, as a drug that has also been studied in HIV, hydroxychloroquine, and flag some of the pitfalls of using therapies that have not been evaluated robustly.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #599514
    Database COVID19

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  5. Article: Behandlung von HIV-Infektionen und AIDS

    Rockstroh, J. K.

    Drug Research

    2016  Volume 66, Issue S 01, Page(s) S15–S16

    Language German
    Publishing date 2016-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2703847-6
    ISSN 2194-9387 ; 2194-9379
    ISSN (online) 2194-9387
    ISSN 2194-9379
    DOI 10.1055/s-0042-112400
    Database Thieme publisher's database

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  6. Book: Compliance in der HIV-Therapie

    Gölz, Jörg / Rockstroh, Jürgen

    (UNI-MED science)

    2001  

    Author's details [Jörg Gölz ; Jürgen Rockstroh]
    Series title UNI-MED science
    Keywords HIV-Infektion ; Compliance
    Subject Adhärenz ; HIV
    Language German
    Size 117 S. : Ill., graph. Darst.
    Publisher UNI-MED-Verl
    Publishing place Bremen u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT013058015
    ISBN 3-89599-557-6 ; 978-3-89599-557-6
    Database Catalogue ZB MED Medicine, Health

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  7. Article ; Online: The use and impact of European Testing Week regional awareness campaigns to increase HIV and viral hepatitis testing coverage.

    Raben, Dorthe / Kahama, C B / Combs, L / Stengaard, Annemarie / Rockstroh, J K / Simões, Daniel / Collins, Ben

    HIV medicine

    2023  Volume 25, Issue 1, Page(s) 154–160

    Abstract: Introduction: Since 2013, the European Testing Week (ETW) awareness campaign has become a key regional event influencing testing efforts for HIV, viral hepatitis, and sexually transmitted infections (STIs) through participation of 720 organizations. ... ...

    Abstract Introduction: Since 2013, the European Testing Week (ETW) awareness campaign has become a key regional event influencing testing efforts for HIV, viral hepatitis, and sexually transmitted infections (STIs) through participation of 720 organizations. Here, we report on a survey from May to June 2022 aimed at assessing the participant-reported impact of the campaign.
    Methods: All past and current participating organizations were asked to complete an online questionnaire between 12 May and 17 June 2022. Multiple choice and open-text questions included organization information, usage of ETW to engage in local testing-related activities, and the effect of a regional campaign to reach a wider audience and generate impact.
    Results: Of the 52 respondents, 34 (65%) stated first participating in ETW 5-10 years ago. ETW was used for awareness raising by 40 respondents (83%), new testing activities by 37 (77%), advocacy initiatives by 15 (31%), and training/capacity building by 18 (38%). For awareness raising, 95% used ETW to highlight the importance of and to encourage testing; for new testing activities, 74% used ETW to reach new groups. In total, 44 (85%) reported added benefits of a Europe-wide campaign compared with national/local campaigns, particularly the increased visibility and collaboration opportunities. Impact at the local level was observed by 24 (51%), and impact at a national level was observed by 20 (43%). A total of 28 (79%) reported increases in the number of tests performed and 25 (75%) reported increases in clients accessing services.
    Conclusions: Regional awareness campaigns reach wider audiences, boost local and national efforts to increase testing, and sensitize key populations about the critical value of testing compared with local/national campaigns.
    MeSH term(s) Humans ; HIV Infections/diagnosis ; HIV Infections/prevention & control ; Sexually Transmitted Diseases ; Europe/epidemiology ; Surveys and Questionnaires
    Language English
    Publishing date 2023-09-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2001932-4
    ISSN 1468-1293 ; 1464-2662
    ISSN (online) 1468-1293
    ISSN 1464-2662
    DOI 10.1111/hiv.13544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Are there any challenges left in hepatitis C virus therapy of HIV-infected patients?

    Bischoff, Jenny / Rockstroh, Jürgen K

    International journal of antimicrobial agents

    2018  Volume 56, Issue 1, Page(s) 105527

    Abstract: Direct-acting antivirals (DAAs) have tremendously improved the treatment of hepatitis C virus (HCV) infections also in human immunodeficiency virus (HIV)-positive individuals. Curing HCV infection is of particular importance in HIV-positive individuals ... ...

    Abstract Direct-acting antivirals (DAAs) have tremendously improved the treatment of hepatitis C virus (HCV) infections also in human immunodeficiency virus (HIV)-positive individuals. Curing HCV infection is of particular importance in HIV-positive individuals as liver disease progression is accelerated in the course of concomitant HIV infection. Former challenges, such as safety and tolerability as well as reduced treatment uptake of pegylated interferon and ribavirin-based treatments, have been overcome with the approval of DAAs. Indeed, rates of discontinuation under modern all-oral DAA therapy in HIV/HCV coinfection have been reported to be <1%. Rates of sustained virological response (SVR) following treatment have aligned with those seen in HCV monoinfected patients, resulting in an equalisation of treatment recommendations for HCV monoinfected and HIV/HCV coinfected patients. Nevertheless, coinfection with HIV has been associated with slightly higher relapse rates in some real-world cohorts, arousing discussion regarding more individualised treatment once again. Moreover, an ongoing epidemic of acute HCV infections in HIV-positive men who have sex with men with high re-infection rates challenges physicians and researchers. The present review gives a concise summary of the remaining challenges in HCV treatment of HIV-positive individuals.
    MeSH term(s) Antiretroviral Therapy, Highly Active/methods ; Antiviral Agents/therapeutic use ; Benzimidazoles/therapeutic use ; Carbamates/therapeutic use ; Coinfection/drug therapy ; Coinfection/virology ; Drug Interactions ; Drug Therapy, Combination ; Fluorenes/therapeutic use ; HIV Infections/pathology ; Hepacivirus/drug effects ; Hepatitis C, Chronic/drug therapy ; Heterocyclic Compounds, 4 or More Rings/therapeutic use ; Humans ; Interferon alpha-2/therapeutic use ; Interferon-alpha/therapeutic use ; Liver Cirrhosis/prevention & control ; Liver Cirrhosis/virology ; Polyethylene Glycols/therapeutic use ; Recombinant Proteins/therapeutic use ; Ribavirin/therapeutic use ; Sexual and Gender Minorities/statistics & numerical data ; Sofosbuvir/therapeutic use ; Sustained Virologic Response ; Treatment Outcome
    Chemical Substances Antiviral Agents ; Benzimidazoles ; Carbamates ; Fluorenes ; Heterocyclic Compounds, 4 or More Rings ; Interferon alpha-2 ; Interferon-alpha ; Recombinant Proteins ; ledipasvir, sofosbuvir drug combination ; Polyethylene Glycols (3WJQ0SDW1A) ; Ribavirin (49717AWG6K) ; peginterferon alfa-2b (G8RGG88B68) ; velpatasvir (KCU0C7RS7Z) ; peginterferon alfa-2a (Q46947FE7K) ; Sofosbuvir (WJ6CA3ZU8B)
    Language English
    Publishing date 2018-08-23
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2018.08.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: HIV-Infektion : Test und Behandlung.

    Rockstroh, J K / Wasmuth, J-C

    Der Internist

    2016  Volume 57, Issue 8, Page(s) 773–783

    Abstract: In Europe depending on the country 15-80 % of all individuals infected with human immunodeficiency virus (HIV) are either not aware of the diagnosis or are diagnosed later. An early HIV diagnosis could, however, considerably improve the prognosis of ... ...

    Title translation HIV infection : Test and treatment.
    Abstract In Europe depending on the country 15-80 % of all individuals infected with human immunodeficiency virus (HIV) are either not aware of the diagnosis or are diagnosed later. An early HIV diagnosis could, however, considerably improve the prognosis of individuals infected with HIV and decrease the risk of new infections; therefore, in the presence of indicator diseases, such as sexually transmitted diseases, oral thrush, herpes zoster and lymphoma, the performance of a HIV test is of utmost importance. A newly diagnosed HIV infection represents an indication for starting antiretroviral combination therapy independent of the clinical stage or CD4 cell count. A decline of the viral burden to below the limit of detection and subsequent continuous suppression of viral replication can prevent transition from HIV to acquired immune deficiency syndrome (AIDS) and if started early enough a normal life expectancy can be achieved. Challenges which remain in HIV therapy are the lifelong daily intake of medication and the complex long-term adverse effects.
    MeSH term(s) Anti-HIV Agents/administration & dosage ; Anti-Retroviral Agents/administration & dosage ; Diagnosis, Differential ; Drug Administration Schedule ; Drug Monitoring ; Early Diagnosis ; Europe ; Evidence-Based Medicine ; HIV Infections/diagnosis ; HIV Infections/therapy ; HIV Infections/virology ; Humans ; Treatment Outcome ; Viral Load/methods
    Chemical Substances Anti-HIV Agents ; Anti-Retroviral Agents
    Language German
    Publishing date 2016-08
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2913-0
    ISSN 1432-1289 ; 0020-9554
    ISSN (online) 1432-1289
    ISSN 0020-9554
    DOI 10.1007/s00108-016-0099-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Mild and Efficient Heterogeneous Hydrogenation of Nitroarenes Facilitated by a Pyrolytically Activated Dinuclear Ni(II)-Ce(III) Diimine Complex.

    Michalke, Jessica / Faust, Kirill / Bögl, Thomas / Bartling, Stephan / Rockstroh, Nils / Topf, Christoph

    International journal of molecular sciences

    2022  Volume 23, Issue 15

    Abstract: We communicate the assembly of a solid, Ce-promoted Ni-based composite that was applied as catalyst for the hydrogenation of nitroarenes to afford the corresponding organic amines. The catalytically active material described herein was obtained through ... ...

    Abstract We communicate the assembly of a solid, Ce-promoted Ni-based composite that was applied as catalyst for the hydrogenation of nitroarenes to afford the corresponding organic amines. The catalytically active material described herein was obtained through pyrolysis of a SiO
    MeSH term(s) Amines ; Catalysis ; Hydrogenation ; Nickel ; Silicon Dioxide
    Chemical Substances Amines ; Silicon Dioxide (7631-86-9) ; Nickel (7OV03QG267)
    Language English
    Publishing date 2022-08-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23158742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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