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  1. Book ; Online ; E-Book: Response of field crops to abiotic stress

    Choudhury, Shuvasish / Moulick, Debojyoti

    current status and future prospects

    2023  

    Author's details edited by Shuvasish Choudhury and Debojyoti Moulick
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiv, 318 Seiten), Illustrationen
    Publisher CRC Press
    Publishing place Boca Raton, Fla
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021699621
    ISBN 978-1-00-080535-2 ; 9781032191966 ; 1-00-080535-2 ; 1032191961
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online ; E-Book: Sustainable agriculture in the era of climate change

    Roychowdhury, Rajib / Choudhury, Shuvasish / Hasanuzzaman, Mirza / Srivastava, Sangeeta

    2020  

    Author's details Rajib Roychowdhury, Shuvasish Choudhury, Mirza Hasanuzzaman, Sangeeta Srivastava, editors
    Keywords Plant breeding ; Plant physiology ; Plant biochemistry ; Plant genetics ; Agriculture ; Climate change
    Language English
    Size 1 Online-Ressource (xxii, 690 Seiten), Illustrationen
    Publisher Springer International Publishing
    Publishing place Cham
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020622642
    ISBN 978-3-030-45669-6 ; 9783030456689 ; 9783030456702 ; 9783030456719 ; 3-030-45669-2 ; 3030456684 ; 3030456706 ; 3030456714
    DOI 10.1007/978-3-030-45669-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Suggesting Ritonavir against COVID-19/SARS-CoV-2.

    Choudhury, Shuvasish / Mazumder, Muhammed Khairujjaman

    Medical hypotheses

    2020  Volume 140, Page(s) 109764

    Keywords covid19
    Language English
    Publishing date 2020-04-22
    Publishing country United States
    Document type Letter
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.109764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
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  5. Article ; Online: Suggesting Ritonavir against COVID-19/SARS-CoV-2

    Choudhury, Shuvasish / Mazumder, Muhammed Khairujjaman

    Medical Hypotheses

    2020  Volume 140, Page(s) 109764

    Keywords General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2020.109764
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Iron (Fe3+)-mediated redox responses and amelioration of oxidative stress in cadmium (Cd2+) stressed mung bean seedlings: a biochemical and computational analysis

    Mazumder, Muhammad Khairujjaman / Moulick, Debojyoti / Choudhury, Shuvasish

    Journal of plant biochemistry and biotechnology. 2022 Mar., v. 31, no. 1

    2022  

    Abstract: The present investigation aims to evaluate the possible ameliorative role of iron (Fe³⁺) on cadmium (Cd²⁺)-induced oxidative stress in mung bean (Vigna radiata L.) seedlings using biochemical and computational approaches. Imposition of Cd²⁺ stress for a ... ...

    Abstract The present investigation aims to evaluate the possible ameliorative role of iron (Fe³⁺) on cadmium (Cd²⁺)-induced oxidative stress in mung bean (Vigna radiata L.) seedlings using biochemical and computational approaches. Imposition of Cd²⁺ stress for a period of 7d showed substantial changes in the growth of root and shoot, and was accompanied by significant Cd²⁺ accumulation and alteration of biochemical parameters. Cd²⁺ stress resulted in a significant reduction in root and shoot length, biomass and moisture content, and increased the levels of reactive oxygen species (ROS) such as hydrogen peroxide (H₂O₂) and superoxide (O₂·⁻). Furthermore, a significant increase in the rate of lipid peroxidation and degradation of antioxidant defence metabolism were observed. Supplementation of the Cd²⁺-stressed seedlings with Fe³⁺ for 7d resulted in amelioration of growth, and restoration of normal cellular homeostasis as observed by considerable changes in oxidative stress parameters as compared to Cd²⁺ treated seedlings alone. Besides, in absence of Fe³⁺, Cd²⁺ accumulation in both root and shoot were significantly high as compared to both control and Fe³⁺-supplemented seedlings. Computational (molecular docking) analysis with superoxide dismutase and catalase as target enzymes revealed that both Cd²⁺ and Fe³⁺ have got affinities for the active sites of these antioxidant enzymes. Thus, it is hereby proposed that Cd²⁺ may potentially interfere with the activities of these antioxidant enzymes, while Fe³⁺ may prevent such interactions. Our findings based on biochemical and computational analysis clearly reveals the ameliorative role of Fe³⁺ on Cd²⁺-induced alterations in growth and oxidative stress in mung bean seedlings.
    Keywords Vigna radiata ; antioxidant activity ; biomass ; biotechnology ; cadmium ; catalase ; homeostasis ; hydrogen peroxide ; iron ; lipid peroxidation ; metabolism ; mung beans ; oxidative stress ; plant biochemistry ; superoxide dismutase ; water content
    Language English
    Dates of publication 2022-03
    Size p. 49-60.
    Publishing place Springer India
    Document type Article
    ZDB-ID 2206337-7
    ISSN 0974-1275 ; 0971-7811
    ISSN (online) 0974-1275
    ISSN 0971-7811
    DOI 10.1007/s13562-021-00654-4
    Database NAL-Catalogue (AGRICOLA)

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  7. Article: Drought-Induced Oxidative Stress in Pearl Millet (

    Choudhury, Shuvasish / Moulick, Debojyoti / Ghosh, Dibakar / Soliman, Mohamed / Alkhedaide, Adel / Gaber, Ahmed / Hossain, Akbar

    Life (Basel, Switzerland)

    2022  Volume 12, Issue 8

    Abstract: We report the impact of drought stress on pearl millet during the early seedling stage and its survival mechanism. Drought stress imposed for a period of 7, 14 and 21 days showed considerable changes in morphophysiological attributes, which were evident ... ...

    Abstract We report the impact of drought stress on pearl millet during the early seedling stage and its survival mechanism. Drought stress imposed for a period of 7, 14 and 21 days showed considerable changes in morphophysiological attributes, which were evident by a decline in seedling elongation, fresh and dry biomass, and relative water content (RWC) and degradation of chlorophyll pigment. Besides this, visible chlorosis lesions were observed in leaves as compared to the control. As compared to the respective controls, a nearly 60% decline in chlorophyll content was recorded after 14 and 21 days of drought stress. In both root and shoot, drought stress raised the reactive oxygen species (ROS) levels. Both H
    Language English
    Publishing date 2022-07-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life12081171
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Tea polyphenols as multi-target therapeutics for Alzheimer's disease: An in silico study.

    Mazumder, Muhammed Khairujjaman / Choudhury, Shuvasish

    Medical hypotheses

    2019  Volume 125, Page(s) 94–99

    Abstract: Alzheimer's disease (AD) is the most common progressive neurodegenerative disease characterized by cognitive decline, dementia, and in later stages complete loss of feelings, sensation and death. The global prevalence of the disease is on the rise, and ... ...

    Abstract Alzheimer's disease (AD) is the most common progressive neurodegenerative disease characterized by cognitive decline, dementia, and in later stages complete loss of feelings, sensation and death. The global prevalence of the disease is on the rise, and it affects 35-40% of the population above 80 years. The pathological hallmarks of the disease include extra-neuronal deposition of amyloid-β (Aβ) as plaques and intra-neuronal hyperphosphorylated tau protein as neurofibrillary tangles, which cause neurodegeneration and cerebral atrophy. Aβ deposition is catalyzed by β-secretase and γ-secretase, while tau hyperphosphorylation is catalyzed by glycogen synthase kinase - 3β (GSK-3β). With neurodegeneration, the level of the neurotransmitter acetylcholine (ACh), as well as acetylcholinesterase (AChE), decreases in the synaptic cleft, called cholinergic deficiency. This leads to the cardinal behavioural abnormalities of AD, which is referred to as cholinergic hypothesis of AD. The other enzyme which degrades ACh is the butyrylcholinesterase (BuChE). Thus, current treatment options of AD include symptomatic treatment to elevate the levels of ACh by inhibiting AChE. However, the currently used drugs cause several side effects, and the quest for novel drugs remains an interesting and essential venture. Since the disease has multiple pathophysiologies, there is an unrelenting need to develop novel drugs and lead molecules capable of inhibiting multiple pathways. The present study hypothesizes use of tea polyphenols against the key drug targets of AD, viz. β-Secretase, γ-Secretase, GSK-3β, AChE and BuChE. The hypothesis has been validated using molecular docking tools. The result indicates that the polyphenols may potentially inhibit these enzymes, similar to their known inhibitors. Thus, the findings are of immense significance in the therapeutic interventions of AD, using tea polyphenols as exciting multi-target drugs.
    MeSH term(s) Acetylcholine/metabolism ; Acetylcholinesterase/metabolism ; Aged, 80 and over ; Alzheimer Disease/drug therapy ; Alzheimer Disease/epidemiology ; Amyloid beta-Peptides/metabolism ; Butyrylcholinesterase/metabolism ; Catalytic Domain ; Cholinesterase Inhibitors/therapeutic use ; Glycogen Synthase Kinase 3 beta/metabolism ; Humans ; Ligands ; Molecular Docking Simulation ; Neurofibrillary Tangles/metabolism ; Oxidative Stress ; Phosphorylation ; Polyphenols/therapeutic use ; Prevalence ; Protein Binding ; Tea/chemistry
    Chemical Substances Amyloid beta-Peptides ; Cholinesterase Inhibitors ; Ligands ; Polyphenols ; Tea ; Glycogen Synthase Kinase 3 beta (EC 2.7.11.1) ; Acetylcholinesterase (EC 3.1.1.7) ; Butyrylcholinesterase (EC 3.1.1.8) ; Acetylcholine (N9YNS0M02X)
    Language English
    Publishing date 2019-02-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 193145-3
    ISSN 1532-2777 ; 0306-9877
    ISSN (online) 1532-2777
    ISSN 0306-9877
    DOI 10.1016/j.mehy.2019.02.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1132: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Secondary metabolites protect against metal and metalloid stress in rice: an in silico investigation using dehydroascorbate reductase

    Choudhury, Shuvasish / Moulick, Debojyoti / Mazumder, Muhammed Khairujjaman

    Acta physiologiae plantarum. 2021 Jan., v. 43, no. 1

    2021  

    Abstract: Plant metabolites including ascorbic acid (AA), reduced glutathione (GSH), serotonin, jasmonic acid (JA) and salicylic acid (SA) alleviate metal/metalloid-induced stress in plants, mainly by regulating the redox homeostasis. This possibly improves stress ...

    Abstract Plant metabolites including ascorbic acid (AA), reduced glutathione (GSH), serotonin, jasmonic acid (JA) and salicylic acid (SA) alleviate metal/metalloid-induced stress in plants, mainly by regulating the redox homeostasis. This possibly improves stress tolerance and augments productivity. The present computational modeling analysis was performed to understand the potential of these five metabolites in ameliorating metal/metalloid stress in rice, using dehydroascorbate reductase (DHAR) as a model. Six metal/metalloid ions (As³⁺, As⁵⁺, Cd²⁺, Cu²⁺, Pb²⁺, Zn²⁺) were used in the study, and the relative affinity, binding geometry and electrostatic surfaces of secondary metabolites and ions with the active site of DHAR were predicted. The results revealed that all the metabolites and ions may potentially interact with the active catalytic site of DHAR. However, the free energies of binding (docking score) of the metabolites (ranging from − 50.64 to − 81.56 kcal/mol) were many-folds higher than those of the ions (ranging from − 16.21 to − 16.23 kcal/mol). On comparison, the docking score of As³⁺ was found to be 28.29% of that of AA. Further, compared to AA, SA had lower score, and GSH, JA and serotonin showed 1.42-, 1.30- and 1.18-fold higher score than AA. Further analysis revealed that the electrostatic surfaces of the metabolites and ions overlap with one another. Statistical analysis was performed to determine the properties of the ligands which are crucial in facilitating interaction of the ligands. Based on the findings, it is argued that the secondary metabolites may interfere with the binding of the ions with DHAR, and when present in higher quantities, these metabolites may ameliorate metal/metalloid-induced stress responses.
    Keywords active sites ; ascorbic acid ; computer simulation ; geometry ; glutathione ; glutathione dehydrogenase (ascorbate) ; homeostasis ; jasmonic acid ; ligands ; models ; rice ; salicylic acid ; secondary metabolites ; serotonin ; statistical analysis ; stress tolerance
    Language English
    Dates of publication 2021-01
    Size p. 3.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 783102-x
    ISSN 1861-1664 ; 0137-5881
    ISSN (online) 1861-1664
    ISSN 0137-5881
    DOI 10.1007/s11738-020-03173-2
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 4051: Show issues

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  10. Article: An assessment of the impact of traditional rice cooking practice and eating habits on arsenic and iron transfer into the food chain of smallholders of Indo-Gangetic plain of South-Asia: Using AMMI and Monte-Carlo simulation model.

    Moulick, Debojyoti / Ghosh, Dibakar / Gharde, Yogita / Majumdar, Arnab / Upadhyay, Munish Kumar / Chakraborty, Deep / Mahanta, Subrata / Das, Anupam / Choudhury, Shuvasish / Brestic, Marian / Alahmadi, Tahani Awad / Ansari, Mohammad Javed / Chandra Santra, Shubhas / Hossain, Akbar

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28296

    Abstract: The current study was designed to investigate the consequences of rice cooking and soaking of cooked rice (CR) with or without arsenic (As) contaminated water on As and Fe (iron) transfer to the human body along with associated health risk assessment ... ...

    Abstract The current study was designed to investigate the consequences of rice cooking and soaking of cooked rice (CR) with or without arsenic (As) contaminated water on As and Fe (iron) transfer to the human body along with associated health risk assessment using additive main-effects and multiplicative interaction (AMMI) and Monte Carlo Simulation model. In comparison to raw rice, As content in cooked rice (CR) and soaked cooked rice (SCR) enhanced significantly (at p < 0.05 level), regardless of rice cultivars and locations (at
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28296
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