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  1. Article ; Online: Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic.

    Aznab, Mozaffar

    International journal of clinical oncology

    2020  Volume 25, Issue 9, Page(s) 1581–1586

    Abstract: Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period.: Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a ...

    Abstract Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period.
    Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90-day period, starting from beginning of this epidemic in Iran, January, to April 19, 2020. For treatment of solid tumor patients, if they did not have symptoms related to COVID-19, just chest X-ray was requested. If they showed COVID-19 related symptoms, high resolution CT scan of lungs was requested. For hematology cancer patients, PCR test for COVID-19 infection was requested as well. Protection measures were considered for personnel of oncology wards.
    Results: 279 Patients were followed up in this 90-day period. No COVID-19 infection was observed in 92 cases of breast cancer, 14 cases of gastric cancer and 12 cases of pancreaticobiliary cancer. However, in 72 cases of colon cancer, 11 cases of lung cancer, 5 cases brain tumors and 12 cases ovarian cancer; 4 cases of COVID-19 were observed. In the hematology cancers group, which included 14 cases of Hodgkin's disease, 23 cases of lymphoproliferative disorder, 12 cases of acute leukemia and 12 cases of multiple myeloma; 3 cases of COVID-19 were observed.
    Conclusion: Patients with cancer who need treatment can be treated by taking some measures. These measures include observing individual and collective protection principles in patients and health-care personnel, increasing patients' awareness particularly about self-care behavior, performing a COVID-19 test, and taking a chest X-ray, before the treatment starts.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Female ; Humans ; Iran/epidemiology ; Male ; Neoplasms/complications ; Neoplasms/therapy ; Pandemics/prevention & control ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Polymerase Chain Reaction ; SARS-CoV-2 ; Tomography, X-Ray Computed
    Keywords covid19
    Language English
    Publishing date 2020-07-11
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1400227-9
    ISSN 1437-7772 ; 1341-9625
    ISSN (online) 1437-7772
    ISSN 1341-9625
    DOI 10.1007/s10147-020-01734-6
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  2. Article ; Online: Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic

    Aznab, Mozaffar

    International Journal of Clinical Oncology

    2020  Volume 25, Issue 9, Page(s) 1581–1586

    Keywords Surgery ; Oncology ; Hematology ; General Medicine ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1400227-9
    ISSN 1437-7772 ; 1341-9625
    ISSN (online) 1437-7772
    ISSN 1341-9625
    DOI 10.1007/s10147-020-01734-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Zs.A 4828: Show issues Location:
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  3. Article ; Online: Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic

    Aznab, Mozaffar

    medRxiv

    Abstract: Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90- ... ...

    Abstract Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90-day period, starting from beginning of this epidemic in Iran, January, to April 19, 2020. For treatment of solid tumor patients, if they did not have symptoms related to COVID-19, just chest X-ray was requested. If they showed COVID-19 related symptoms, High Resolution CT scan of lungs was requested. For hematology cancer patients, PCR test for COVID-19 infection was requested as well. Protection measures were considered for personnel of oncology wards. Results: In this study, 279 patients were followed up in this 90-day period. No COVID-19 infection was observed in 92 cases of breast cancer, 72 cases of colon cancer, 14 cases of gastric cancer and 12 cases of pancreaticobiliary cancer .However, in 11 cases of lung cancer, 5 cases brain tumors and 12 cases ovarian cancer; 3 case of COVID-19 were observed. In the hematology cancers group, which included 14 cases of Hodgkin Lymphoma, 23 cases of lymphoproliferative disorder, 12 cases of acute leukemia and 12 cases of multiple myeloma; three of COVID-19 were observed. Conclusion: Patients with cancer who need treatment can be treated by taking some measures. These measures include observing individual and collective protection principles in patients and health-care personnel, increasing patients awareness particularly about self-care behavior, performing a COVID-19 test, and taking a chest X ray, before the treatment starts
    Keywords covid19
    Language English
    Publishing date 2020-06-01
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2020.05.26.20102889
    Database COVID19

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  4. Article ; Online: Evaluation of COVID 19 infection in 279 cancer patients treated during a 90-day period in 2020 pandemic

    Aznab, Mozaffar

    Abstract: Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90- ... ...

    Abstract Background: The aim of this study was investigation of COVID-19 disease and its outcome in cancer patients who needed treatment, in a 90-day period. Methods: Cancer patient who required treatment, were evaluated for potential COVID-19 infection in a 90-day period, starting from beginning of this epidemic in Iran, January, to April 19, 2020. For treatment of solid tumor patients, if they did not have symptoms related to COVID-19, just chest X-ray was requested. If they showed COVID-19 related symptoms, High Resolution CT scan of lungs was requested. For hematology cancer patients, PCR test for COVID-19 infection was requested as well. Protection measures were considered for personnel of oncology wards. Results: In this study, 279 patients were followed up in this 90-day period. No COVID-19 infection was observed in 92 cases of breast cancer, 72 cases of colon cancer, 14 cases of gastric cancer and 12 cases of pancreaticobiliary cancer .However, in 11 cases of lung cancer, 5 cases brain tumors and 12 cases ovarian cancer; 3 case of COVID-19 were observed. In the hematology cancers group, which included 14 cases of Hodgkin Lymphoma, 23 cases of lymphoproliferative disorder, 12 cases of acute leukemia and 12 cases of multiple myeloma; three of COVID-19 were observed. Conclusion: Patients with cancer who need treatment can be treated by taking some measures. These measures include observing individual and collective protection principles in patients and health-care personnel, increasing patients awareness particularly about self-care behavior, performing a COVID-19 test, and taking a chest X ray, before the treatment starts
    Keywords covid19
    Publisher MedRxiv; WHO
    Document type Article ; Online
    Note WHO #Covidence: #20102889
    DOI 10.1101/2020.05.26.20102889
    Database COVID19

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  5. Article ; Online: Salivary and serum levels of soluble E-cadherin in patients with gastrointestinal cancers: A comparative study.

    Aznab, Mozaffar / Shahhosseini, Rezvan / Safaei, Mohsen / Mozaffari, Hamid Reza

    Journal of cancer research and therapeutics

    2023  Volume 19, Issue 7, Page(s) 1982–1987

    Abstract: Aim: According to the literature, high levels of salivary soluble E-cadherin may be lined to advanced stage and poor prognosis in cancers. This research aimed at comparing salivary and serum levels of soluble E-cadherin in cases with esophageal, gastric, ...

    Abstract Aim: According to the literature, high levels of salivary soluble E-cadherin may be lined to advanced stage and poor prognosis in cancers. This research aimed at comparing salivary and serum levels of soluble E-cadherin in cases with esophageal, gastric, and colorectal cancers.
    Methods: This case-control research was performed on 68 patients with gastrointestinal cancers and 57 healthy volunteers as a control group to measure salivary and serum levels of soluble E-cadherin using ELISA kits.
    Results: The results showed a statistically significant difference between salivary and serum levels of soluble E-cadherin in the case group, as opposed to the control group (P = 0.031). The salivary level of soluble E-cadherin in the control group was 2.138 ng/mL on average lower than that that in the case group. The median salivary level of soluble E-cadherin among cases with lymph node involvement was significantly higher compared with its median level in the control group (P = 0.049). Soluble E-cadherin salivary level and other variables, such as metastasis and cancer stage, were directly correlated, but it was not statistically significant.
    Conclusion: According to the findings, the salivary level of soluble E-cadherin among cases with gastric cancer could be considered as a prognostic marker, but the diagnostic value of saliva could not be judged in esophageal and colorectal cancers because of small sample size, and more investigations are required for a definite conclusion.
    MeSH term(s) Humans ; Cadherins ; Colorectal Neoplasms ; Enzyme-Linked Immunosorbent Assay ; Gastrointestinal Neoplasms/diagnosis ; Stomach Neoplasms ; Case-Control Studies
    Chemical Substances Cadherins
    Language English
    Publishing date 2023-04-27
    Publishing country India
    Document type Journal Article
    ZDB-ID 2187633-2
    ISSN 1998-4138 ; 0973-1482
    ISSN (online) 1998-4138
    ISSN 0973-1482
    DOI 10.4103/jcrt.jcrt_702_22
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  6. Article ; Online: Evaluation of Safety and Side Effects COVID-19 Vaccine in Cancer Patients Being Treated.

    Aznab, Mozaffar / Chalehchaleh, Maryam / Dokoshkani, Somayeh / Rezaei, Maryam

    Asian Pacific journal of cancer prevention : APJCP

    2022  Volume 23, Issue 4, Page(s) 1263–1270

    Abstract: According to the instructions of Iran's National Corona Response Committee in the Iranian Ministry of Health and Medical Education, patients undergoing treatments for their cancer are prioritized in Covid-19 vaccination. The present study was therefore ... ...

    Abstract According to the instructions of Iran's National Corona Response Committee in the Iranian Ministry of Health and Medical Education, patients undergoing treatments for their cancer are prioritized in Covid-19 vaccination. The present study was therefore conducted to investigate the toxicity and acute side-effects of a Covid-19 vaccine in cancer patients presenting to Medical Oncology Clinic of Kermanshah University of Medical Science. After excluding the patients with active infection and the recently-infected ones with Covid-19, they underwent the vaccination. The patients with cell counts exceeding 3,000 received two doses of the vaccine with a 21-day interval and treatment of their underlying disease was postponed for 7 days. The side-effects were mild and tolerable and included fever (case 10), pain at the injection site (7), dizziness (7), body pain (6), abdominal pain (6), myalgia (6), headache (6), chills (3), shortness of breath (3), diarrhea (1), runny nose (1) and dryness of the throat (1). No significant toxicity was reported in the patients who were safely vaccinated under the supervision of the medical oncology clinic.
    MeSH term(s) COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Iran/epidemiology ; Neoplasms/therapy ; Pain
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-04-01
    Publishing country Thailand
    Document type Journal Article
    ZDB-ID 2218955-5
    ISSN 2476-762X ; 1513-7368
    ISSN (online) 2476-762X
    ISSN 1513-7368
    DOI 10.31557/APJCP.2022.23.4.1263
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  7. Article: Clinical Characteristics and Risk Factors of COVID-19 in 60 Adult Cancer Patients.

    Aznab, Mozaffar / Eskandari Roozbahani, Narges / Moazen, Homa

    Clinical Medicine Insights. Oncology

    2022  Volume 16, Page(s) 11795549221074168

    Abstract: Background: During the pandemic of COVID-19, cancer patients have been considered as one high-risk group in the morbidity and mortality of COVID-19. This study aimed to describe the clinical symptoms and risk factors of COVID-19 in cancer patients.: ... ...

    Abstract Background: During the pandemic of COVID-19, cancer patients have been considered as one high-risk group in the morbidity and mortality of COVID-19. This study aimed to describe the clinical symptoms and risk factors of COVID-19 in cancer patients.
    Method: In a prospective cross-sectional study, during a year, all cancer patients who underwent chemotherapy and/or targeted therapy in our clinic (Kermanshah, Iran) were followed up in terms of getting COVID-19. We analyzed the effect of tumor features and demographic information on clinical manifestations, survival status, therapeutic outcomes, and severity of the disease COVID-19 in 2 categories of cancer (hematologic and solid cancers).
    Results: Most of the patients (68%) were in the solid tumor category, including breast cancer (24.4%), colon cancer (22%), and gastric cancer (9.8%). There was a statistically significant difference between 2 categories of cancer in the clinical manifestations: the stage of cancer and survival status (
    Conclusions: Thrombocytopenia, anemia, and diarrhea are symptoms that, along with common symptoms such as lung involvement, difficulty breathing, and the need for a ventilator, increase the risk of death in cancer patients with COVID-19.
    Language English
    Publishing date 2022-01-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2577877-8
    ISSN 1179-5549
    ISSN 1179-5549
    DOI 10.1177/11795549221074168
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  8. Article ; Online: The association between microRNA polymorphisms and the risk of childhood acute lymphoblastic leukemia: A meta-analysis.

    Navabi, Abbas / Aznab, Mozaffar / Heydarpour, Fatemeh

    Cancer epidemiology

    2022  Volume 81, Page(s) 102285

    Abstract: The aim of this meta-analysis was to determine the relationship between microRNA polymorphisms and the risk of childhood acute lymphoblastic leukemia comprehensively. PubMed, EMBASE, Scopus, Web of Science, the Cochrane Library, Global Index Medicus, ... ...

    Abstract The aim of this meta-analysis was to determine the relationship between microRNA polymorphisms and the risk of childhood acute lymphoblastic leukemia comprehensively. PubMed, EMBASE, Scopus, Web of Science, the Cochrane Library, Global Index Medicus, Clinicaltrials.gov, ProQuest, and Open Grey databases were used to find relevant papers. Using the STATA 16.0 and CMA 3.0 software, the significance of relationships between microRNA polymorphisms and childhood acute lymphoblastic leukemia risk was evaluated using odds ratios (ORs) and 95 % confidence intervals (95 % CIs) for five genetic models. The results of the meta-analysis showed that there was no significant association between the polymorphism of miR-146a rs2910164 and childhood acute lymphoblastic leukemia risk in different genetic models. Also, in the sensitivity analysis, removing Xue's study from the analysis indicated that both the homozygote and recessive models are significantly affected. Additionally, there was a statistically significant relationship between the polymorphisms of pri-miR-34b/c rs4938723 (in the homozygote and recessive models) and miR-612 rs12803915 (in the allele and dominant models) and childhood acute lymphoblastic leukemia risk. These findings suggest that the rs4938723 and rs12803915 polymorphisms may have a role in the development of childhood acute lymphoblastic leukemia.
    Language English
    Publishing date 2022-11-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2508729-0
    ISSN 1877-783X ; 1877-7821
    ISSN (online) 1877-783X
    ISSN 1877-7821
    DOI 10.1016/j.canep.2022.102285
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    Zs.A 1427: Show issues Location:
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  9. Article: Evaluation of the Role of Tumor-Infiltrating Lymphocytes and CD8

    Shojaei, Shahram / Aznab, Mozaffar / Rahimi, Amirmasoud / Ahmadi, Seyed Mojtaba / Eslampia, Kumars / Golpazir, Arash / Iravani, Masoud

    International journal of hematology-oncology and stem cell research

    2023  Volume 17, Issue 1, Page(s) 9–17

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-08-24
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2652853-8
    ISSN 2008-2207 ; 2008-3009
    ISSN (online) 2008-2207
    ISSN 2008-3009
    DOI 10.18502/ijhoscr.v17i1.11708
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  10. Article ; Online: Long-term Results of Adjuvant Imatinib Treatment for Localized Gastrointestinal Stromal Tumors after Surgery

    Aznab, Mozaffar / Akhmadi, Sayed Mojtaba

    Asian Pacific journal of cancer prevention : APJCP

    2018  Volume 19, Issue 1, Page(s) 39–43

    Language English
    Publishing date 2018-01-27
    Publishing country Thailand
    Document type Journal Article
    ISSN 2476-762X
    ISSN (online) 2476-762X
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