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Article ; Online: Sudden bilateral vision loss in a COVID-19 patient: A case report.

Atum, Mahmut / Demiryürek, Bekir Enes

2021 Volume 69, Issue 8, Page(s) 2227–2228

Abstract: We present a Coronavirus disease 2019 (COVID-19) patient who developed sudden bilateral vision loss after a bilateral occipital ischemic stroke and without a history of stroke risk factors. An 84-year-old man was admitted to the emergency room with ... ...

Abstract	We present a Coronavirus disease 2019 (COVID-19) patient who developed sudden bilateral vision loss after a bilateral occipital ischemic stroke and without a history of stroke risk factors. An 84-year-old man was admitted to the emergency room with bilateral sudden vision loss while receiving Favipiravir treatment for 5 days following a COVID-19 diagnosis. The patient had no history of stroke risk factors, such as hypertension, diabetes mellitus, coronary artery disease, or arrhythmia. Diffusion magnetic resonance imaging of the patient revealed acute ischemia in the bilateral posterior occipital lobe and bilateral cerebellar hemisphere. We conclude that COVID-19 may rarely cause bilateral ischemic stroke presented only in the form of vision loss.
MeSH term(s)	Aged, 80 and over ; Blindness/diagnosis ; Blindness/etiology ; COVID-19 ; COVID-19 Testing ; Humans ; Male ; Occipital Lobe ; SARS-CoV-2
Language	English
Publishing date	2021-07-14
Publishing country	India
Document type	Case Reports
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_3706_20
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Article: Retinal morphological changes during the two years of follow-up in Parkinson's disease.

Atum, Mahmut / Demiryürek, Bekir Enes

Ideggyogyaszati szemle

2021 Volume 74, Issue 1-2, Page(s) 57–63

Abstract: Background and purpose: The study aims to investigate the relationship between the progression of idiopathic Parkinson's disease (IPD) and retinal morphology.: Methods: The study was carried out with 23 patients diagnosed with early-stage IPD (phases ...

Title translation	A retina morfológiai változásai Parkinson-kóros betegek kétéves utánkövetése során.
Abstract	Background and purpose: The study aims to investigate the relationship between the progression of idiopathic Parkinson's disease (IPD) and retinal morphology. Methods: The study was carried out with 23 patients diagnosed with early-stage IPD (phases 1 and 2 of the Hoehn and Yahr scale) and 30 age-matched healthy controls. All patients were followed up at least two years, with 6-month intervals (initial, 6th month, 12th month, 18th month, and 24th month), and detailed neurological and ophthalmic examinations were performed at each follow-up. Unified Parkinson's Disease Rating Scale part III (UPDRS Part III) scores, Hoehn and Yahr (H&Y) scores, best-corrected visual acuity (BCVA), intraocular pressure (IOP) measurement, central macular thickness (CMT) and retinal nerve fiber layer (RNFL) thickness were analyzed at each visit. Results: The average age of the IPD and control groups was 43.96 ± 4.88 years, 44.53 ± 0.83 years, respectively. The mean duration of the disease in the IPD group was 7.48 ± 5.10 months at the start of the study (range 0-16). There was no statistically significant difference in BCVA and IOP values between the two groups during the two-year follow-up period (p> 0.05, p> 0.05, respectively). Average and superior quadrant RNFL thicknesses were statistically different between the two groups at 24 months and there was no significant difference between other visits (p=0.025, p=0.034, p> 0.05, respectively). There was no statistically significant difference in CMT between the two groups during the follow-up period (p> 0.05). Conclusion: Average and superior quadrant RNFL thicknesses were significantly thinning with the progression of IPD.
MeSH term(s)	Adult ; Follow-Up Studies ; Humans ; Middle Aged ; Nerve Fibers ; Parkinson Disease ; Retina/diagnostic imaging ; Tomography, Optical Coherence
Language	English
Publishing date	2021-01-19
Publishing country	Hungary
Document type	Journal Article
ZDB-ID	2240317-6
ISSN	0019-1442
ISSN	0019-1442
DOI	10.18071/isz.74.0057
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Article: Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in Patients with Retinal Artery Occlusion.

Atum, Mahmut / Alagöz, Gürsoy

Journal of ophthalmic & vision research

2020 Volume 15, Issue 2, Page(s) 195–200

Abstract: Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them.!## ...

Abstract	Purpose: This study aimed to compare the neutrophil-to-lymphocyte (NLR) and platelet-to-lymphocyte (PLR) ratios in patients with retinal artery occlusion (RAO) with those from a healthy control population and to identify the relationship between them. Methods: Forty-six patients with RAO and fifty-one healthy control subjects were included in this retrospective case-control study. RAO was diagnosed following an ophthalmic examination and fluorescein angiography (FA). Blood neutrophil, lymphocyte, and platelet counts were recorded for each of the 97 subjects, from which NLR and PLR values were calculated. Results: There were 46 patients (28 male [M], 18 female [F]) in the RAO group and 51 patients (27 M, 24 F) in the control group. No significant differences were found between patients with RAO and the control subjects in terms of gender and age (P Conclusion: NLRs were significantly increased in patients with RAO compared to the control subjects.
Language	English
Publishing date	2020-04-06
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ISSN	2008-2010
ISSN	2008-2010
DOI	10.18502/jovr.v15i2.6737
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Article ; Online: Comparison of three different intraocular lens implantation techniques in the absence of capsular support: sutured scleral, haptic flanged intrascleral, and four flanged intrascleral fixations.

Boz, Ali Altan Ertan / Atum, Mahmut / Özmen, Sedat / Yuvacı, İsa / Çelik, Erkan

International ophthalmology

2023 Volume 43, Issue 12, Page(s) 5045–5053

Abstract: Introduction: After lens extraction, if the capsular bag insufficiency occurs, there are different IOL implantation techniques. IOL implantation in the posterior chamber is safer in eyes with low endothelial cell count, peripheral anterior synechiae, ... ...

Abstract	Introduction: After lens extraction, if the capsular bag insufficiency occurs, there are different IOL implantation techniques. IOL implantation in the posterior chamber is safer in eyes with low endothelial cell count, peripheral anterior synechiae, shallow anterior chamber, and glaucoma. Alternative approaches for scleral fixation techniques, both with and without sutures, continue to undergo development. In this study, we aimed to compare the postoperative outcomes of the sutured scleral fixation (SSF), haptic flanged intrascleral fixation (HFISF) and four flanged intrascleral fixation (FFISF) IOL implantation techniques in eyes with the absence of capsular support. Materials and methods: A hundred and thirty-seven aphakic eyes with the absence of capsular support were included in the study. The patients were divided into three groups: group 1-SSF, group 2-HFISF (Yamane technique), and group 3-FFISF. Surgical time in minutes, preoperative and postoperative parameters such as best corrected visual acuity (BCVA), corneal astigmatism, lenticular astigmatism, intraocular pressure (IOP), specular microscopy, central macular thickness (CMT) were recorded. Pseudophacodonesis was assessed at 6 months postoperatively using a slit lamp, and early and late complications were recorded. Results: Of the 137 eyes, 69 eyes were included in the SSF group, 41 eyes in the HFISF group, and 27 eyes in the FFISF group. No statistically significant differences were observed among the three groups in terms of age, gender, preoperative mean BCVA, corneal astigmatism, IOP, endothelial cell density, and CMT. It was observed that the mean BCVA significantly improved compared to the preoperative visual acuity in all three groups. Postoperative lenticular astigmatism, pseudophacodonesis score, percentage of the endothelial cell loss were found to be higher in FFISF groups. The surgical time was found to be shorter in the HFISF group. IOL decentration was observed in 1.44% of the SSF group and 7.40% of the FFISF group. Cystoid macular edema was observed in 5.79% of the SSF group, 4.87% of the HFISF group, and 7.40% of the FFISF group. Retinal detachment was observed in 1.44% of the SSF group and 7.31% of the HFISF group. Conclusions: The optimal technique for treating aphakia without capsular support remains uncertain. Surgeons are tasked with a complex decision, aiming for both excellent vision and minimal risk. This decision is based on their expertise, the distinctive ocular condition of the patient, and the availability of essential operating room equipment. In this study, the following findings were observed: in the HFISF technique, the average surgical time was found to be shorter, the SSF technique demonstrated greater stability in terms of astigmatism and pseudophacodonesis and the FFISF technique was recognized for its relatively straightforward application method. It is important to note that the three IOL implantation techniques yielded comparable outcomes in terms of postoperative BCVA, as well as early and late complications.
MeSH term(s)	Humans ; Lens Implantation, Intraocular/methods ; Lenses, Intraocular ; Astigmatism/surgery ; Haptic Technology ; Sclera/surgery ; Corneal Diseases/surgery ; Retrospective Studies ; Suture Techniques ; Postoperative Complications/surgery
Language	English
Publishing date	2023-10-18
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-023-02907-8
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Article: Delirium due to the use of topical cyclopentolate hydrochloride.

Atum, Mahmut / Çelik, Erkan / Alagöz, Gürsoy

Ideggyogyaszati szemle

2020 Volume 73, Issue 1-2, Page(s) 51–52

Abstract: Introduction - Our aim is to present a rare case where a child had delirium manifestation after instillation of cyclopentolate. Case presentation - A 7-year old patient was seen in our outpatient clinic, and cyclopentolate was dropped three times at 10 ... ...

Title translation	Cyclopentolat-hydrochlorid szemcsepp alkalmazása következtében kialakuló delírium.
Abstract	Introduction - Our aim is to present a rare case where a child had delirium manifestation after instillation of cyclopentolate. Case presentation - A 7-year old patient was seen in our outpatient clinic, and cyclopentolate was dropped three times at 10 minutes intervals in both eyes. The patient suddenly developed behavioral disorders along with gait disturbance, and complained of visual hallucinations 20-25 minutes after the last drop. The patient was transferred to intensive care unit and 0.02 mg/kg IV. physostigmine was administered. The patient improved after minutes of onset of physostigmine, and was discharged with total recovery after 30 minutes. Conclusion - Delirium is a rare systemic side effect of cyclopentolate. The specific antidote is physostigmine, which can be used in severely agitated patients who are not responding to other therapies.
MeSH term(s)	Antidotes/administration & dosage ; Child ; Cyclopentolate/adverse effects ; Delirium/chemically induced ; Hallucinations ; Humans ; Parasympatholytics/adverse effects ; Physostigmine/administration & dosage
Chemical Substances	Antidotes ; Parasympatholytics ; Physostigmine (9U1VM840SP) ; Cyclopentolate (I76F4SHP7J)
Language	English
Publishing date	2020-02-14
Publishing country	Hungary
Document type	Case Reports ; Journal Article
ZDB-ID	2240317-6
ISSN	0019-1442
ISSN	0019-1442
DOI	10.18071/isz.73.0051
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Article ; Online: A new method of arterial stiffness measurement in pseudoexfoliation syndrome: cardio-ankle vascular index.

Atum, Mahmut / Kocayiğit, İbrahim / Sahinkuş, Salih / Coşkun, Şule Bahadır / Çelik, Erkan

Arquivos brasileiros de oftalmologia

2022 Volume 85, Issue 6, Page(s) 578–583

Abstract: Purpose: To investigate whether pseudoexfoliation syndrome affects arterial stiffness by using cardio-ankle vascular index measurement.: Methods: This cross-sectional case-control study included 55 patients with pseudoexfoliation syndrome and 106 age- ...

Abstract	Purpose: To investigate whether pseudoexfoliation syndrome affects arterial stiffness by using cardio-ankle vascular index measurement. Methods: This cross-sectional case-control study included 55 patients with pseudoexfoliation syndrome and 106 age- and gender-matched healthy control subjects. All subjects underwent a complete ophthalmic exa mination of both eyes and cardio-ankle vascular index measu rements. Echocardiographic and body mass index measurements were performed in all patients, and the results were recorded. A binary regression model was used to determine the relationship between cardio-ankle vascular index and pseudoexfoliation. Results: There were no significant differences between the pseudoexfoliation and control groups in baseline clinical and demographic characteristics, echocardiographic measurements of left ventricular ejection fraction, and body mass index. The mean cardio-ankle vascular index value was significantly higher in the pseudoexfoliation group than in the controls (9.47 ± 1.23 vs. 8.33 ± 1.50, p<0.001). Intraocular pressure was significantly higher in the pseudoexfoliation group than in the controls (18.31 ± 1.78 vs. 15.24 ± 2.42 mm Hg, p<0.05). Although the logistic regression analysis showed that mean cardio-ankle vascular index and IOP values were positively associated with pseudoexfoliation syndrome (Odds ratios (OR) = 1.973, 95% CI, 1.051-3.706, p=0.035; OR=3.322, 95% CI = 2.000-5.520, p<0.001, respectively), the Pearson correlation analysis revealed a borderline significant positive correlation between age and mean cardio-ankle vascular index and a significant positive correlation between dyslipidemia and intraocular pressure and mean cardio-ankle vascular index (r=0.265, p=0.050; r=0.337, p=0.012; r=0.433, p=0.001, respectively). Conclusion: Our findings demonstrated that cardio-ankle vascular index values increased in patients with pseudoexfoliation syndrome.
MeSH term(s)	Humans ; Vascular Stiffness ; Case-Control Studies ; Cross-Sectional Studies ; Ankle/blood supply ; Exfoliation Syndrome ; Stroke Volume ; Ventricular Function, Left
Language	English
Publishing date	2022-02-14
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	603915-7
ISSN	1678-2925 ; 0004-2749
ISSN (online)	1678-2925
ISSN	0004-2749
DOI	10.5935/0004-2749.20220085
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Article ; Online: Can the CRP/albumin Ratio be Used as a New Indicator of Activation in Patients with Uveitis?

Bozkurt, Erdinç / Muhafiz, Ersin / Sengul, Dilek / Uçak, Turgay / Atum, Mahmut

Ocular immunology and inflammation

2020 Volume 29, Issue 5, Page(s) 1017–1022

Abstract: ... ...

Abstract	Purpose
MeSH term(s)	Adult ; Albumins/metabolism ; Biomarkers/blood ; Blood Cell Count ; Blood Platelets/metabolism ; Blood Sedimentation ; C-Reactive Protein/metabolism ; Cross-Sectional Studies ; Female ; Humans ; Lymphocyte Count ; Lymphocytes/metabolism ; Male ; Middle Aged ; Platelet Count ; ROC Curve ; Retrospective Studies ; Uveitis/blood ; Uveitis/diagnosis ; Young Adult
Chemical Substances	Albumins ; Biomarkers ; C-Reactive Protein (9007-41-4)
Language	English
Publishing date	2020-03-03
Publishing country	England
Document type	Journal Article
ZDB-ID	1193873-0
ISSN	1744-5078 ; 0927-3948
ISSN (online)	1744-5078
ISSN	0927-3948
DOI	10.1080/09273948.2020.1714061
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Article ; Online: Increased cardio-ankle vascular index values in patients with acute branch retinal vein occlusion.

Kocayigit, Ibrahim / Atum, Mahmut / Sahinkus, Salih / Aksoy, Murat / Can, Yusuf

Indian journal of ophthalmology

2020 Volume 68, Issue 5, Page(s) 868–871

Abstract: Purpose: Patients with retinal vein occlusions (RVOs) are at increased risk of cardiovascular disease. Arterial stiffness is an independent risk factor for cardiovascular events. Our aim is to evaluate the arterial stiffness in patients with acute ... ...

Abstract	Purpose: Patients with retinal vein occlusions (RVOs) are at increased risk of cardiovascular disease. Arterial stiffness is an independent risk factor for cardiovascular events. Our aim is to evaluate the arterial stiffness in patients with acute branch retinal vein occlusion (BRVO) by using cardio-ankle vascular index (CAVI). Methods: This prospective study included 42 patients (18 male, mean age 57.5 ± 11.3) with acute BRVO and a matched control group (by age, sex, and presence of hypertension) with 70 (26 male, mean age 54.4 ± 9.4) patients. All patients and control subjects underwent complete ocular examination and CAVI measurement. BRVO was diagnosed based on clinical examination. Results: There were no significant differences between baseline clinical and demographic characteristics, echocardiographic measurements of left ventricular ejection fraction, systolic and diastolic blood pressure, and body mass index of the BRVO and control group. Both right and left CAVI values were found significantly higher in BRVO group (7.94 ± 1.53 vs 7.28 ± 1.25, P < 0.05 and 8.06 ± 1.41 vs 7.30 ± 1.26, P < 0.05, respectively). There were no significant difference in right and left ankle-brachial index values between the groups (1.05 ± 0.10 vs 1.06 ± 0.08, P = 0.46 and 1.04 ± 0.12 vs 1.05 ± 0.08, P = 0.46, respectively). Conclusion: Arterial stiffness is an important mediator of cardiovascular diseases. We found that CAVI which is a novel marker of the arterial stiffness is increased in patients with acute BRVO compared to controls.
MeSH term(s)	Aged ; Ankle ; Blood Pressure ; Humans ; Male ; Middle Aged ; Prospective Studies ; Retinal Vein Occlusion/diagnosis ; Stroke Volume ; Ventricular Function, Left
Language	English
Publishing date	2020-04-21
Publishing country	India
Document type	Journal Article
ZDB-ID	187392-1
ISSN	1998-3689 ; 0301-4738
ISSN (online)	1998-3689
ISSN	0301-4738
DOI	10.4103/ijo.IJO_1300_19
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Article ; Online: Outcomes of the Ophthalmic Examinations in Patients Infected by SARS-CoV-2.

Boz, Ali Altan Ertan / Atum, Mahmut / Çakır, Burçin / Karabay, Oğuz / Çelik, Erkan / Alagöz, Gürsoy

Ocular immunology and inflammation

2020 Volume 29, Issue 4, Page(s) 638–641

Abstract: ... ...

Abstract	Purpose
MeSH term(s)	COVID-19/diagnosis ; COVID-19/virology ; Conjunctivitis/diagnosis ; Conjunctivitis/virology ; Cross-Sectional Studies ; Eye Infections, Viral/diagnosis ; Eye Infections, Viral/virology ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Prognosis ; SARS-CoV-2 ; Slit Lamp Microscopy ; Uveitis, Anterior/diagnosis ; Uveitis, Anterior/virology
Language	English
Publishing date	2020-11-23
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1193873-0
ISSN	1744-5078 ; 0927-3948
ISSN (online)	1744-5078
ISSN	0927-3948
DOI	10.1080/09273948.2020.1844904
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Article: Bilateral acute angle-closure glaucoma induced by duloxetine.

Mahmut, Atum / Tunc, Vildan / Demiryurek, Enes / Gursoy, Alagoz

Ideggyogyaszati szemle

2018 Volume 70, Issue 9-10, Page(s) 358–360

Abstract: Introduction - To present a rare case of bilateral acute angle-closure glaucoma secondary to duloxetine administered for the treatment of depression. Case presentation - A 46 year old woman developed bilateral closed angle glaucoma after 15 days of ... ...

Title translation	Duloxetin által kiváltott, kétoldali, akut zárt zugú glaucoma.
Abstract	Introduction - To present a rare case of bilateral acute angle-closure glaucoma secondary to duloxetine administered for the treatment of depression. Case presentation - A 46 year old woman developed bilateral closed angle glaucoma after 15 days of duloxetine usage. Intraocular pressures (IOP) were 52 and 55 mm Hg in right and left eyes respectively, with shallow anterior chamber and angle closure on gonioscopy. Discontinuing duloxetine treatment, initiation of antiglaucomatous treatment and bilateral Nd:YAG Laser iridotomy obtained normalized IOP and anterior chamber depth. Conclusion - Duloxetine, used in the treatment of depression can be responsible for acute angle-closure glaucoma by leading to mydriasis and ciliary effusion.
MeSH term(s)	Antidepressive Agents/adverse effects ; Antidepressive Agents/therapeutic use ; Duloxetine Hydrochloride/adverse effects ; Duloxetine Hydrochloride/therapeutic use ; Female ; Glaucoma, Angle-Closure/diagnostic imaging ; Glaucoma, Angle-Closure/drug therapy ; Glaucoma, Angle-Closure/etiology ; Humans ; Middle Aged
Chemical Substances	Antidepressive Agents ; Duloxetine Hydrochloride (9044SC542W)
Language	English
Publishing date	2018-06-05
Publishing country	Hungary
Document type	Case Reports
ZDB-ID	2240317-6
ISSN	0019-1442
ISSN	0019-1442
DOI	10.18071/isz.70.0358
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