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Article ; Online: [No title information]

Schlager, Justin Gabriel / Hartmann, Daniela / Kendziora, Benjamin

Dermatologie (Heidelberg, Germany)

2023 Volume 75, Issue 1, Page(s) 70

Title translation	Bakterielle Endokarditis und hämatogene Gelenkprotheseninfektion : Perioperative Antibiose in der Dermatochirurgie sinnvoll?
MeSH term(s)	Humans ; Antibiosis ; Arthroplasty, Replacement ; Joint Prosthesis ; Endocarditis, Bacterial
Language	German
Publishing date	2023-11-22
Publishing country	Germany
Document type	Journal Article
ISSN	2731-7013
ISSN (online)	2731-7013
DOI	10.1007/s00105-023-05264-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online ; Thesis: Computed tomography for the diagnosis of coronary artery disease and magnetic resonance imaging for quantifying salvaged myocardium after myocardial infarction

Kendziora, Benjamin [Verfasser]

2021

Author's details	Benjamin Kendziora
Keywords	Medizin, Gesundheit ; Medicine, Health
Subject code	sg610
Language	English
Publisher	Medizinische Fakultät Charité - Universitätsmedizin Berlin
Publishing place	Berlin
Document type	Book ; Online ; Thesis
Database	Digital theses on the web

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Article ; Online: Postoperative Infektionen und perioperative Antibiose in der Dermatochirurgie.

Schlager, Justin Gabriel / Hartmann, Daniela / Kendziora, Benjamin

Dermatologie (Heidelberg, Germany)

2023 Volume 74, Issue 11, Page(s) 827–834

Abstract: Background: Postoperative wound infections represent the most common complication in dermatosurgery. Given the low incidence and heterogeneous data, no standards for perioperative antibiotic prophylaxis (PAP) have been established in clinical practice.!# ...

Title translation	Surgical site infection and perioperative antibiotics in dermatosurgery.
Abstract	Background: Postoperative wound infections represent the most common complication in dermatosurgery. Given the low incidence and heterogeneous data, no standards for perioperative antibiotic prophylaxis (PAP) have been established in clinical practice. Objectives: To summarize the current evidence on risk factors for postoperative wound infection in dermatosurgery and the new recommendations on PAP. Materials and methods: Relevant study data and current recommendations were summarized descriptively. Results: Current evidence suggests that the following factors are associated with an increased risk of wound infection after dermatosurgical procedures: surgery to the lower extremity or the ear, postoperative hemorrhage, defect closure by flap or skin graft, large wound defect, immunosuppression, and male sex. Probably not affecting the risk of infection are diabetes, obesity, age, smoking, use of a blood thinner, multiple surgeries, or wound healing by second intention. Not all risk factors affect the risk of infection equally. They must be weighted differently and only in combination do they increase the risk of wound infection in a clinically relevant way. According to a current position paper of the German Society for Dermatosurgery, the indication for PAP should be made individually and only if multiple factors are present. Furthermore, patients with increased risk for bacterial endocarditis or hematogenic endoprosthesis infection should receive PAP prior to septic skin surgery. Conclusion: In dermatologic surgery, PAP should be restricted to patients at high risk for wound infection. Further indications are the prevention of bacterial endocarditis and hematogenic endoprosthesis infection in high-risk individuals prior to septic surgery.
MeSH term(s)	Humans ; Male ; Surgical Wound Infection/epidemiology ; Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Skin Transplantation ; Endocarditis, Bacterial/drug therapy
Chemical Substances	Anti-Bacterial Agents
Language	German
Publishing date	2023-10-12
Publishing country	Germany
Document type	English Abstract ; Journal Article ; Review
ISSN	2731-7013
ISSN (online)	2731-7013
DOI	10.1007/s00105-023-05233-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Has the quality of reporting improved since it became mandatory to use the Standards for Reporting Diagnostic Accuracy?

Stahl, Ann-Christine / Tietz, Anne-Sophie / Dewey, Marc / Kendziora, Benjamin

Insights into imaging

2023 Volume 14, Issue 1, Page(s) 85

Abstract: Objectives: To investigate whether making the Standards for Reporting Diagnostic Accuracy (STARD) mandatory by the leading journal 'Radiology' in 2016 improved the quality of reporting of diagnostic accuracy studies.: Methods: A validated search term ...

Abstract	Objectives: To investigate whether making the Standards for Reporting Diagnostic Accuracy (STARD) mandatory by the leading journal 'Radiology' in 2016 improved the quality of reporting of diagnostic accuracy studies. Methods: A validated search term was used to identify diagnostic accuracy studies published in Radiology in 2015 and 2019. STARD adherence was assessed by two independent reviewers. Each item was scored as yes (1 point) if adequately reported or as no (0 points) if not. The total STARD score per article was calculated. Wilcoxon-Mann-Whitney tests were used to evaluate differences of the total STARD scores between 2015 and 2019. In addition, the total STARD score was compared between studies stratified by study design, citation rate, and data collection. Results: The median number of reported STARD items for the total of 66 diagnostic accuracy studies from 2015 to 2019 was 18.5 (interquartile range [IQR] 17.5-20.0) of 29. Adherence to the STARD checklist significantly improved the STARD score from a median of 18.0 (IQR 15.5-19.5) in 2015 to a median of 19.5 (IQR 18.5-21.5) in 2019 (p < 0.001). No significant differences were found between studies stratified by mode of data collection (prospective vs. retrospective studies, p = 0.68), study design (cohort vs. case-control studies, p = 0.81), and citation rate (two groups divided by median split [< 0.56 citations/month vs. ≥ 0.56 citations/month], p = 0.54). Conclusions: Making use of the STARD checklist mandatory significantly increased the adherence with reporting standards for diagnostic accuracy studies and should be considered by editors and publishers for widespread implementation. Critical relevance statement: Editors may consider making reporting guidelines mandatory to improve the scientific quality.
Language	English
Publishing date	2023-05-15
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2543323-4
ISSN	1869-4101
ISSN	1869-4101
DOI	10.1186/s13244-023-01432-7
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Article ; Online: Prognostic value of the myocardial salvage index measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging after ST-segment elevation myocardial infarction: A systematic review and meta-regression analysis.

Kendziora, Benjamin / Dewey, Marc

PloS one

2020 Volume 15, Issue 2, Page(s) e0228736

Abstract: In all patients with ST-segment elevation myocardial infarction, risk stratification should be performed before discharge. The measurement of therapy efficiency with magnetic resonance imaging has been proposed as part of the risk assessment, but it has ... ...

Abstract	In all patients with ST-segment elevation myocardial infarction, risk stratification should be performed before discharge. The measurement of therapy efficiency with magnetic resonance imaging has been proposed as part of the risk assessment, but it has not been adopted widely. This meta-analysis was conducted to summarize published data on the prognostic value of the proportion of salvaged myocardium inside previously ischemic myocardium (myocardial salvage index) measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging after ST-segment elevation myocardial infarction. Random and mixed effects models were used for analyzing the data of 10 studies with 2,697 patients. The pooled myocardial salvage index, calculated as the proportion of non-necrotic myocardium inside edematous myocardium measured by T2-weighted and T1-weighted late gadolinium enhancement MRI, was 43.0% (95% confidence interval: 37.4, 48.6). The pooled length of follow-up was 12.3 months (95% confidence interval: 7.0, 17.6). The pooled incidence of major cardiac events during follow-up, defined as cardiac death, nonfatal myocardial infarction, or admission for heart failure, was 10.6% (95% confidence interval: 5.7, 15.5). The applied mixed effects model showed an absolute decrease of 1.7% in the incidence of major cardiac events during follow-up (95% confidence interval: 1.6, 1.9) with every 1% of increase in the myocardial salvage index. The heterogeneity between studies was considerable (τ = 21.3). Analysis of aggregated follow-up data after ST-segment elevation myocardial infarction suggests that the myocardial salvage index measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging provides prognostic information on the risk of major cardiac events, but considerable heterogeneity exists between studies.
MeSH term(s)	Contrast Media/chemistry ; Gadolinium/chemistry ; Humans ; Magnetic Resonance Imaging ; Myocardium/pathology ; Prognosis ; Risk Factors ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/pathology ; Severity of Illness Index
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2020-02-13
Publishing country	United States
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0228736
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Antibiotic Prophylaxis of Surgical Site Infections in Cutaneous Surgery: A Prospective Observational Study.

Kendziora, Benjamin / Patzer, Kathrin / French, Lars E / Schlager, Justin G / Hartmann, Daniela

Acta dermato-venereologica

2023 Volume 103, Page(s) adv4469

Abstract: The use of perioperative antibiotic prophylaxis in cutaneous surgery is controversial due to unclear efficacy and, thus, potentially unnecessary side-effects. This prospective observational study analysed the efficacy of oral perioperative antibiotic ... ...

Abstract	The use of perioperative antibiotic prophylaxis in cutaneous surgery is controversial due to unclear efficacy and, thus, potentially unnecessary side-effects. This prospective observational study analysed the efficacy of oral perioperative antibiotic prophylaxis in preventing surgical site infections. Adult patients undergoing cutaneous surgery between August 2020 and May 2021 at Ludwig-Maximilian University Hospital Munich, Germany, without prior signs of infection were eligible. Propensity score weighting was used for covariate adjustment to account for non-randomized treatment assignment. Of 758 included patients, 23 received perioperative antibiotic prophylaxis (3.0%). In this group, a surgical site infection occurred in 1 of 45 lesions (2.2%) compared with 76 of 1,189 lesions (6.5%) in the group without perioperative antibiotic prophylaxis (735 patients, 97.0%). With covariate adjustment, the odds ratio for the occurrence of a surgical site infection in patients receiving perioperative antibiotic prophylaxis was 0.114 (95% confidence interval 0.073-0.182; p <0.001) on a per lesion level. The number of lesions needed to treat to prevent 1 surgical site infection was 17.6 (95% confidence interval 16.8-19.2). This prospective observational study shows a reduction in the incidence of surgical site infection in cutaneous surgery performed with perioperative antibiotic prophylaxis. The large size difference between the 2 study groups limits the study.
MeSH term(s)	Adult ; Humans ; Antibiotic Prophylaxis/adverse effects ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/prevention & control ; Anti-Bacterial Agents/therapeutic use ; Prospective Studies ; Dermatologic Surgical Procedures/adverse effects
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2023-05-10
Publishing country	Sweden
Document type	Observational Study ; Journal Article
ZDB-ID	80007-7
ISSN	1651-2057 ; 0001-5555
ISSN (online)	1651-2057
ISSN	0001-5555
DOI	10.2340/actadv.v103.4469
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Article ; Online: Has the quality of reporting improved since it became mandatory to use the Standards for Reporting Diagnostic Accuracy?

Ann-Christine Stahl / Anne-Sophie Tietz / Marc Dewey / Benjamin Kendziora

Insights into Imaging, Vol 14, Iss 1, Pp 1-

2023 Volume 10

Abstract: Abstract Objectives To investigate whether making the Standards for Reporting Diagnostic Accuracy (STARD) mandatory by the leading journal ‘Radiology’ in 2016 improved the quality of reporting of diagnostic accuracy studies. Methods A validated search ... ...

Abstract	Abstract Objectives To investigate whether making the Standards for Reporting Diagnostic Accuracy (STARD) mandatory by the leading journal ‘Radiology’ in 2016 improved the quality of reporting of diagnostic accuracy studies. Methods A validated search term was used to identify diagnostic accuracy studies published in Radiology in 2015 and 2019. STARD adherence was assessed by two independent reviewers. Each item was scored as yes (1 point) if adequately reported or as no (0 points) if not. The total STARD score per article was calculated. Wilcoxon–Mann–Whitney tests were used to evaluate differences of the total STARD scores between 2015 and 2019. In addition, the total STARD score was compared between studies stratified by study design, citation rate, and data collection. Results The median number of reported STARD items for the total of 66 diagnostic accuracy studies from 2015 to 2019 was 18.5 (interquartile range [IQR] 17.5–20.0) of 29. Adherence to the STARD checklist significantly improved the STARD score from a median of 18.0 (IQR 15.5–19.5) in 2015 to a median of 19.5 (IQR 18.5–21.5) in 2019 (p < 0.001). No significant differences were found between studies stratified by mode of data collection (prospective vs. retrospective studies, p = 0.68), study design (cohort vs. case–control studies, p = 0.81), and citation rate (two groups divided by median split [< 0.56 citations/month vs. ≥ 0.56 citations/month], p = 0.54). Conclusions Making use of the STARD checklist mandatory significantly increased the adherence with reporting standards for diagnostic accuracy studies and should be considered by editors and publishers for widespread implementation. Critical relevance statement Editors may consider making reporting guidelines mandatory to improve the scientific quality. Graphical Abstract
Keywords	Checklist ; Accuracy ; Diagnostic tests ; Reference standards ; Research design ; Medical physics. Medical radiology. Nuclear medicine ; R895-920
Subject code	001 ; 333
Language	English
Publishing date	2023-05-01T00:00:00Z
Publisher	SpringerOpen
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Has the STARD statement improved the quality of reporting of diagnostic accuracy studies published in European Radiology?

Stahl, Ann-Christine / Tietz, Anne-Sophie / Kendziora, Benjamin / Dewey, Marc

European radiology

2022 Volume 33, Issue 1, Page(s) 97–105

Abstract: Objectives: To investigate whether encouraging authors to follow the Standards for Reporting Diagnostic Accuracy (STARD) guidelines improves the quality of reporting of diagnostic accuracy studies.: Methods: In mid-2017, European Radiology started ... ...

Abstract	Objectives: To investigate whether encouraging authors to follow the Standards for Reporting Diagnostic Accuracy (STARD) guidelines improves the quality of reporting of diagnostic accuracy studies. Methods: In mid-2017, European Radiology started encouraging its authors to follow the STARD guidelines. Our MEDLINE search identified 114 diagnostic accuracy studies published in European Radiology in 2015 and 2019. The quality of reporting was evaluated by two independent reviewers using the revised STARD statement. Item 11 was excluded because a meaningful decision about adherence was not possible. Student's t test for independent samples was used to analyze differences in the mean number of reported STARD items between studies published in 2015 and in 2019. In addition, we calculated differences related to the study design, data collection, and citation rate. Results: The mean total number of reported STARD items for all 114 diagnostic accuracy studies analyzed was 15.9 ± 2.6 (54.8%) of 29 items (range 9.5-22.5). The quality of reporting of diagnostic accuracy studies was significantly better in 2019 (mean ± standard deviation (SD), 16.3 ± 2.7) than in 2015 (mean ± SD, 15.1 ± 2.3; p < 0.02). No significant differences in the reported STARD items were identified in relation to study design (p = 0.13), data collection (p = 0.87), and citation rate (p = 0.09). Conclusion: The quality of reporting of diagnostic accuracy studies according to the STARD statement was moderate with a slight improvement since European Radiology started to recommend its authors to follow the STARD guidelines. Key points: • The quality of reporting of diagnostic accuracy studies was moderate with a mean total number of reported STARD items of 15.9 ± 2.6. • The adherence to STARD was significantly better in 2019 than in 2015 (16.3 ± 2.7 vs. 15.1 ± 2.3; p = 0.016). • No significant differences in the reported STARD items were identified in relation to study design (p = 0.13), data collection (p = 0.87), and citation rate (p = 0.09).
Language	English
Publishing date	2022-07-30
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-022-09008-7
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prognostic value of the myocardial salvage index measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging after ST-segment elevation myocardial infarction

Benjamin Kendziora / Marc Dewey

PLoS ONE, Vol 15, Iss 2, p e

A systematic review and meta-regression analysis.

2020 Volume 0228736

Abstract	In all patients with ST-segment elevation myocardial infarction, risk stratification should be performed before discharge. The measurement of therapy efficiency with magnetic resonance imaging has been proposed as part of the risk assessment, but it has not been adopted widely. This meta-analysis was conducted to summarize published data on the prognostic value of the proportion of salvaged myocardium inside previously ischemic myocardium (myocardial salvage index) measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging after ST-segment elevation myocardial infarction. Random and mixed effects models were used for analyzing the data of 10 studies with 2,697 patients. The pooled myocardial salvage index, calculated as the proportion of non-necrotic myocardium inside edematous myocardium measured by T2-weighted and T1-weighted late gadolinium enhancement MRI, was 43.0% (95% confidence interval: 37.4, 48.6). The pooled length of follow-up was 12.3 months (95% confidence interval: 7.0, 17.6). The pooled incidence of major cardiac events during follow-up, defined as cardiac death, nonfatal myocardial infarction, or admission for heart failure, was 10.6% (95% confidence interval: 5.7, 15.5). The applied mixed effects model showed an absolute decrease of 1.7% in the incidence of major cardiac events during follow-up (95% confidence interval: 1.6, 1.9) with every 1% of increase in the myocardial salvage index. The heterogeneity between studies was considerable (τ = 21.3). Analysis of aggregated follow-up data after ST-segment elevation myocardial infarction suggests that the myocardial salvage index measured by T2-weighted and T1-weighted late gadolinium enhancement magnetic resonance imaging provides prognostic information on the risk of major cardiac events, but considerable heterogeneity exists between studies.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: MRI for measuring therapy efficiency after revascularisation in ST-segment elevation myocardial infarction: a systematic review and meta-regression analysis.

Kendziora, Benjamin / Stier, Heli / Schlattmann, Peter / Dewey, Marc

BMJ open

2020 Volume 10, Issue 9, Page(s) e034359

Abstract: Objective: To summarise existing data on the relation between the time from symptom onset until revascularisation (time to reperfusion) and the myocardial salvage index (MSI) calculated as proportion of non-necrotic myocardium inside oedematous ... ...

Abstract	Objective: To summarise existing data on the relation between the time from symptom onset until revascularisation (time to reperfusion) and the myocardial salvage index (MSI) calculated as proportion of non-necrotic myocardium inside oedematous myocardium on T2-weighted and T1-weighted late gadolinium enhancement MRI after ST-segment elevation myocardial infarction (STEMI). Methods: Studies including patients with revascularised STEMI and stating both the time to reperfusion and the MSI measured by T2-weighted and T1-weighted late gadolinium enhancement MRI were searched in MEDLINE, EMBASE and ISI Web of Science until 16 May 2020. A mixed effects model was used to evaluate the relation between the time to reperfusion and the MSI. The gender distribution and mean age in included patient groups, the timing of MRI, used MRI sequences and image interpretation methodology were included in the mixed effects model to explore between-study heterogeneity. Results: We included 38 studies with 5106 patients. The pooled MSI was 42.6% (95% CI: 38.1 to 47.1). The pooled time to reperfusion was 3.8 hours (95% CI: 3.5 to 4.0). Every hour of delay in reperfusion was associated with an absolute decrease of 13.1% (95% CI: 11.5 to 14.6; p<0.001) in the MSI. Between-study heterogeneity was considerable (σ Conclusions: The MSI on T2-weighted and T1-weighted late gadolinium enhancement MRI correlates inversely with the time to reperfusion, which indicates that cardioprotection achieved by minimising the time to reperfusion leads to a higher MSI. The analysis revealed considerable heterogeneity between studies. The heterogeneity could partly be explained by differences in the gender distribution, timing and interpretation of MRI suggesting that the MRI-assessed MSI is not only influenced by cardioprotective therapy but also by patient characteristics and MRI parameters.
MeSH term(s)	Contrast Media ; Gadolinium ; Humans ; Magnetic Resonance Imaging ; Myocardium ; Regression Analysis ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/surgery ; Treatment Outcome
Chemical Substances	Contrast Media ; Gadolinium (AU0V1LM3JT)
Language	English
Publishing date	2020-09-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2019-034359
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