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  1. Article: Emergency digital cholangioscopy-assisted electrohydraulic lithotripsy for basket impaction with an entrapped bile duct stone.

    Hara, Akane / Minaga, Kosuke / Otsuka, Yasuo / Tanaka, Hidekazu / Takenaka, Mamoru / Kudo, Masatoshi

    Endoscopy international open

    2024  Volume 12, Issue 2, Page(s) E271–E273

    Language English
    Publishing date 2024-02-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-2246-6568
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  2. Article ; Online: Chromosome Conformation Capture for Large Genomes.

    Kawaguchi, Akane / Tanaka, Elly M

    Methods in molecular biology (Clifton, N.J.)

    2022  Volume 2562, Page(s) 291–318

    Abstract: The gigantic 32Gb Axolotl genome inspires fascinating questions such as: how such a big genome is organized and packed in nuclei and how regulation of gene transcription can happen over such large genomic distances. Currently, there are many technical ... ...

    Abstract The gigantic 32Gb Axolotl genome inspires fascinating questions such as: how such a big genome is organized and packed in nuclei and how regulation of gene transcription can happen over such large genomic distances. Currently, there are many technical challenges when we investigate chromatin architecture in axolotl. For example, probing promoter-enhancer interactions in such a large genome. Chromatin capture methods (e.g., Chromatin Conformation Capture) have been used in a variety of species. The large size of the axolotl nuclei and its genome requires the adaptation of such methods. Here, we describe a detailed protocol for high-throughput genome-wide conformation capture (Hi-C) using axolotl limb cells. This Hi-C library preparation protocol can also be used to prepare libraries from other nonmodel organisms such as Lungfish and Cephalopods. We believe that our protocol could be useful for a variety of animal systems including other salamanders.
    MeSH term(s) Animals ; High-Throughput Nucleotide Sequencing/methods ; Genome ; Chromosomes/genetics ; Chromatin/genetics ; Genomics/methods ; Nucleic Acid Conformation
    Chemical Substances Chromatin
    Language English
    Publishing date 2022-10-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-2659-7_20
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  3. Article ; Online: Effect of farm Hazard Analysis and Critical Control Point (farm HACCP) certification efforts on emissions of volatile organic compounds from livestock sheds in Japan.

    Tanaka, Nobuyuki / Aizawa, Arika / Miyazaki, Akane / Ando, Yoshitake

    Animal science journal = Nihon chikusan Gakkaiho

    2023  Volume 94, Issue 1, Page(s) e13908

    Abstract: Farm HACCP" incorporates the concept of Hazard Analysis and Critical Control Points (HACCP) into farm animal husbandry and sanitation management to ensure the safety of livestock products and improve productivity. Implementing farm HACCP may reduce the ... ...

    Abstract "Farm HACCP" incorporates the concept of Hazard Analysis and Critical Control Points (HACCP) into farm animal husbandry and sanitation management to ensure the safety of livestock products and improve productivity. Implementing farm HACCP may reduce the emission of volatile organic compounds (VOCs), which are derived from livestock manure and are responsible for odors, PM
    MeSH term(s) Animals ; Female ; Cattle ; Swine ; Livestock ; Farms ; Volatile Organic Compounds/analysis ; Hazard Analysis and Critical Control Points ; Japan ; Chickens ; Air Pollutants/analysis
    Chemical Substances Volatile Organic Compounds ; Air Pollutants
    Language English
    Publishing date 2023-12-19
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 2095161-9
    ISSN 1740-0929 ; 1344-3941
    ISSN (online) 1740-0929
    ISSN 1344-3941
    DOI 10.1111/asj.13908
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  4. Article ; Online: School-aged children's movement behaviours and subjective health complaints in Japan: a cross-sectional study during COVID-19 pandemic-related school closures and after school reopenings.

    Kasai, Akane / Shikano, Akiko / Tanaka, Ryo / Yoshinaga, Mari / Noi, Shingo

    BMC public health

    2024  Volume 24, Issue 1, Page(s) 1204

    Abstract: Background: Social restrictions associated with the COVID-19 pandemic have altered children's movement behaviours and impacted their mental health. However, the influence of social restrictions on subjective health complaints remains inadequately ... ...

    Abstract Background: Social restrictions associated with the COVID-19 pandemic have altered children's movement behaviours and impacted their mental health. However, the influence of social restrictions on subjective health complaints remains inadequately understood. This study compared adherence to 24-hour movement behaviour guidelines and the prevalence of subjective health complaints during school closure and one year after reopening. We also examined how combinations of adherence to movement behaviour recommendations relate to subjective health complaints.
    Methods: A repeated cross-sectional survey was conducted at two points. The first survey in May 2020 included 1535 (766 boys and 769 girls) participants during school closures, while the second survey from May to July 2021 involved 1125 (583 boys and 542 girls) participants one year after school reopening. The questionnaire covered socio-demographics, physical activity, screen time, sleep, and subjective health complaints. Differences between periods were analysed using chi-square tests. Logistic regression models assessed the association between adherence to guidelines and subjective health complaints.
    Results: During school closure, children were more likely to meet 'only sleep' recommendations and have irritability and lethargy symptoms. Irrespective of sex, those adhering to two or all three recommendations (excluding physical activity and screen time) had a lower risk of symptoms related to physical and mental pain, fatigue, irritability, and lethargy as compared to those who met none of the recommendations.
    Conclusions: Children should meet at least one physical activity or screen time recommendation in addition to sleep recommendations for subjective health. Strategies considering the priority of each movement behaviour are crucial, even during abnormal situations, such as pandemic-related social restrictions. This study offers insightful findings concerning children's mental health issues during unprecedented and massive disasters or crises.
    MeSH term(s) Humans ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/psychology ; Cross-Sectional Studies ; Male ; Female ; Japan/epidemiology ; Child ; Schools ; Exercise/psychology ; Screen Time ; Pandemics ; Sleep ; Adolescent ; Surveys and Questionnaires ; Child Behavior/psychology ; Diagnostic Self Evaluation
    Language English
    Publishing date 2024-04-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-024-18712-6
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  5. Article: Differential In Vivo Effects on Cancer Models by Recorded Magnetic Signals Derived From a Healing Technique.

    Bengston, William / Cizdziel, Paul / Tanaka, Akane / Matsuda, Hiroshi

    Dose-response : a publication of International Hormesis Society

    2023  Volume 21, Issue 2, Page(s) 15593258231179903

    Abstract: Previous research on "healing-with-intent" has reasonably demonstrated the validity of the phenomenon at least when a human healer is present and involved. However, in order for healing to be adopted into more conventional therapies, it must be able to ... ...

    Abstract Previous research on "healing-with-intent" has reasonably demonstrated the validity of the phenomenon at least when a human healer is present and involved. However, in order for healing to be adopted into more conventional therapies, it must be able to be made scalable. The present study tests the effects of a scalable recording of the Bengston Healing Method on 3 cancer models. BalbC mice engrafted with 4T1 breast cancer cells, C57BL mice with melanoma B16 cells, and C3H mice with bladder MBT-2 wells were exposed to a recording of healing intent for 4 hours/day for approximately 1 month. In the breast cancer model, there was significant tumor suppression and a reduction of anemia marker HCT in treated vs control mice. In the melanoma model, there were no significant differences except for a reduction in platelet count among the treated mice. For unknown reasons, tumor growth never became evident in the bladder cancer model. While the effects of the recording seem to vary by model, there appears reason to pursue scalable delivery systems in multiple models and with multiple doses.
    Language English
    Publishing date 2023-06-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2440820-7
    ISSN 1559-3258
    ISSN 1559-3258
    DOI 10.1177/15593258231179903
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  6. Article ; Online: A case of gas gangrene caused by Clostridium septicum with undiagnosed advanced colon cancer.

    Sumigama, Anna / Goto, Yusuke / Ohno, Yoshiyuki / Ohata, Hiroto / Okuno, Mitsuru / Onogi, Akane / Watanabe, Naoki / Tanaka, Takuji / Kanoh, Hiroyuki

    The Journal of dermatology

    2024  

    Language English
    Publishing date 2024-03-03
    Publishing country England
    Document type Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.17167
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  7. Article ; Online: Chloroplast dehydroascorbate reductase and glutathione cooperatively determine the capacity for ascorbate accumulation under photooxidative stress conditions.

    Hamada, Akane / Tanaka, Yasuhiro / Ishikawa, Takahiro / Maruta, Takanori

    The Plant journal : for cell and molecular biology

    2023  Volume 114, Issue 1, Page(s) 68–82

    Abstract: Ascorbate is an indispensable redox buffer essential for plant growth and stress acclimation. Its oxidized form, dehydroascorbate (DHA), undergoes rapid degradation unless it is recycled back into ascorbate by glutathione (GSH)-dependent enzymatic or non- ...

    Abstract Ascorbate is an indispensable redox buffer essential for plant growth and stress acclimation. Its oxidized form, dehydroascorbate (DHA), undergoes rapid degradation unless it is recycled back into ascorbate by glutathione (GSH)-dependent enzymatic or non-enzymatic reactions, with the enzymatic reactions catalyzed by dehydroascorbate reductases (DHARs). Our recent study utilizing an Arabidopsis quadruple mutant (∆dhar pad2), which lacks all three DHARs (∆dhar) and is deficient in GSH (pad2), has posited that these GSH-dependent reactions operate in a complementary manner, enabling a high accumulation of ascorbate under high-light stress. However, as Arabidopsis DHAR functions in the cytosol or chloroplasts, it remained unclear which isoform played a more significant role in cooperation with GSH-dependent non-enzymatic reactions. To further comprehend the intricate network of ascorbate recycling systems in plants, we generated mutant lines lacking cytosolic DHAR1/2 or chloroplastic DHAR3, or both, in another GSH-deficient background (cad2). A comprehensive comparison of ascorbate profiles in these mutants under conditions of photooxidative stress induced by various light intensities or methyl viologen unequivocally demonstrated that chloroplastic DHAR3, but not cytosolic isoforms, works in concert with GSH to accumulate ascorbate. Our findings further illustrate that imbalances between stress intensity and recycling capacity significantly impact ascorbate pool size and tolerance to photooxidative stress. Additionally, it was found that the absence of DHARs and GSH deficiency do not impede ascorbate biosynthesis, at least in terms of transcription or activity of biosynthetic enzymes. This study provides insights into the robustness of ascorbate recycling.
    MeSH term(s) Arabidopsis/metabolism ; Ascorbic Acid/metabolism ; Glutathione/metabolism ; Chloroplasts/metabolism ; Oxidative Stress
    Chemical Substances glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) ; Ascorbic Acid (PQ6CK8PD0R) ; Glutathione (GAN16C9B8O)
    Language English
    Publishing date 2023-02-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.16117
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    In stock of ZB MED Bonn / Germany

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  8. Article ; Online: Evolutionary insights into strategy shifts for the safe and effective accumulation of ascorbate in plants.

    Maruta, Takanori / Tanaka, Yasuhiro / Yamamoto, Kojiro / Ishida, Tetsuya / Hamada, Akane / Ishikawa, Takahiro

    Journal of experimental botany

    2024  Volume 75, Issue 9, Page(s) 2664–2681

    Abstract: Plants accumulate high concentrations of ascorbate, commonly in their leaves, as a redox buffer. While ascorbate levels have increased during plant evolution, the mechanisms behind this phenomenon are unclear. Moreover, has the increase in ascorbate ... ...

    Abstract Plants accumulate high concentrations of ascorbate, commonly in their leaves, as a redox buffer. While ascorbate levels have increased during plant evolution, the mechanisms behind this phenomenon are unclear. Moreover, has the increase in ascorbate concentration been achieved without imposing any detrimental effects on the plants? In this review, we focus on potential transitions in two regulatory mechanisms related to ascorbate biosynthesis and the availability of cellular dehydroascorbate (DHA) during plant evolution. The first transition might be that the trigger for the transcriptional induction of VTC2, which encodes the rate-limiting enzyme in ascorbate biosynthesis, has shifted from oxidative stress (in green algae) to light/photosynthesis (in land plants), probably enabling the continuous accumulation of ascorbate under illumination. This could serve as a preventive system against the unpredictable occurrence of oxidative stress. The second transition might be that DHA-degrading enzymes, which protect cells from the highly reactive DHA in green algae and mosses, have been lost in ferns or flowering plants. Instead, flowering plants may have increased glutathione concentrations to reinforce the DHA reduction capacity, possibly allowing ascorbate accumulation and avoiding the toxicity of DHA. These potential transitions may have contributed to strategies for plants' safe and effective accumulation of ascorbate.
    MeSH term(s) Ascorbic Acid/metabolism ; Plants/metabolism ; Biological Evolution ; Oxidative Stress
    Chemical Substances Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2976-2
    ISSN 1460-2431 ; 0022-0957
    ISSN (online) 1460-2431
    ISSN 0022-0957
    DOI 10.1093/jxb/erae062
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    In stock of ZB MED Bonn / Germany

    Z 55/29: Show issues

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  9. Article: Emergency digital cholangioscopy-assisted electrohydraulic lithotripsy for basket impaction with an entrapped bile duct stone

    Hara, Akane / Minaga, Kosuke / Otsuka, Yasuo / Tanaka, Hidekazu / Takenaka, Mamoru / Kudo, Masatoshi

    Endoscopy International Open

    2024  Volume 12, Issue 02, Page(s) E271–E273

    Language English
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722 ; 2196-9736
    ISSN (online) 2196-9736
    ISSN 2364-3722 ; 2196-9736
    DOI 10.1055/a-2246-6568
    Database Thieme publisher's database

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  10. Article ; Online: Chloroplast dehydroascorbate reductase and glutathione cooperatively determine the capacity for ascorbate accumulation under photooxidative stress conditions

    Hamada, Akane / Tanaka, Yasuhiro / Ishikawa, Takahiro / Maruta, Takanori

    The Plant Journal. 2023 Apr., v. 114, no. 1 p.68-82

    2023  

    Abstract: Ascorbate is an indispensable redox buffer essential for plant growth and stress acclimation. Its oxidized form, dehydroascorbate (DHA), undergoes rapid degradation unless it is recycled back into ascorbate by glutathione (GSH)‐dependent enzymatic or non‐ ...

    Abstract Ascorbate is an indispensable redox buffer essential for plant growth and stress acclimation. Its oxidized form, dehydroascorbate (DHA), undergoes rapid degradation unless it is recycled back into ascorbate by glutathione (GSH)‐dependent enzymatic or non‐enzymatic reactions, with the enzymatic reactions catalyzed by dehydroascorbate reductases (DHARs). Our recent study utilizing an Arabidopsis quadruple mutant (∆dhar pad2), which lacks all three DHARs (∆dhar) and is deficient in GSH (pad2), has posited that these GSH‐dependent reactions operate in a complementary manner, enabling a high accumulation of ascorbate under high‐light stress. However, as Arabidopsis DHAR functions in the cytosol or chloroplasts, it remained unclear which isoform played a more significant role in cooperation with GSH‐dependent non‐enzymatic reactions. To further comprehend the intricate network of ascorbate recycling systems in plants, we generated mutant lines lacking cytosolic DHAR1/2 or chloroplastic DHAR3, or both, in another GSH‐deficient background (cad2). A comprehensive comparison of ascorbate profiles in these mutants under conditions of photooxidative stress induced by various light intensities or methyl viologen unequivocally demonstrated that chloroplastic DHAR3, but not cytosolic isoforms, works in concert with GSH to accumulate ascorbate. Our findings further illustrate that imbalances between stress intensity and recycling capacity significantly impact ascorbate pool size and tolerance to photooxidative stress. Additionally, it was found that the absence of DHARs and GSH deficiency do not impede ascorbate biosynthesis, at least in terms of transcription or activity of biosynthetic enzymes. This study provides insights into the robustness of ascorbate recycling.
    Keywords Arabidopsis ; acclimation ; biosynthesis ; chloroplasts ; cytosol ; glutathione ; glutathione dehydrogenase (ascorbate) ; mutants ; paraquat ; photooxidation ; plant growth
    Language English
    Dates of publication 2023-04
    Size p. 68-82.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 1088037-9
    ISSN 1365-313X ; 0960-7412
    ISSN (online) 1365-313X
    ISSN 0960-7412
    DOI 10.1111/tpj.16117
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

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