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  1. Article ; Online: Rapid and Accurate Quantification of Viable

    Wang, Chenglong / Liu, Siyuan / Wang, Ziquan / Wang, Meng / Pang, Huimin / Liu, Yingying / Chang, Haiyan / Sui, Zhiwei

    Analytical chemistry

    2024  Volume 96, Issue 3, Page(s) 1093–1101

    Abstract: ... ...

    Abstract Lactobacillus
    MeSH term(s) Humans ; Lactobacillus/genetics ; Real-Time Polymerase Chain Reaction/methods ; Flow Cytometry/methods ; In Situ Hybridization, Fluorescence ; Infant Formula ; Azides ; Bacteria ; Microbial Viability ; Propidium/analogs & derivatives
    Chemical Substances propidium monoazide ; Azides ; Propidium (36015-30-2)
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1508-8
    ISSN 1520-6882 ; 0003-2700
    ISSN (online) 1520-6882
    ISSN 0003-2700
    DOI 10.1021/acs.analchem.3c03742
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4033: Show issues Location:
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  2. Article ; Online: Pressure-Modulated Interface Engineering toward Realizing Core@Shell Configuration Transition.

    Lv, Pengfei / Zhao, Dianlong / Ma, Zhiwei / Cong, Ming / Sui, Yongming / Xiao, Guanjun / Zou, Bo

    Nano letters

    2023  Volume 23, Issue 24, Page(s) 11982–11988

    Abstract: The strained interface of core@shell nanocrystals (NCs) can effectively modulate the energy level alignment, thereby significantly affecting the optical properties. Herein, the unique photoluminescence (PL) response of doped Mn ions is introduced as a ... ...

    Abstract The strained interface of core@shell nanocrystals (NCs) can effectively modulate the energy level alignment, thereby significantly affecting the optical properties. Herein, the unique photoluminescence (PL) response of doped Mn ions is introduced as a robust probe to detect the targeted pressure-strain relation of CdS@ZnS NCs. Results show that the core experiences actually less pressure than the applied external pressure, attributed to the pressure-induced optimized interface that reduces the compressive strain on core. The pressure difference between core and shell increases the conduction band and valence band offsets and further achieves the core@shell configuration transition from quasi type II to type I. Accordingly, the PL intensity of CdS@ZnS NCs slightly increases, along with a faster blue-shift rate of PL peak under low pressure. This study elucidates the interplay between external physical pressure and interfacial chemical stress for core@shell NCs, leading to precise construction of interface engineering for practical applications.
    Language English
    Publishing date 2023-12-05
    Publishing country United States
    Document type Journal Article
    ISSN 1530-6992
    ISSN (online) 1530-6992
    DOI 10.1021/acs.nanolett.3c04359
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  3. Article ; Online: Air-Liquid Interface Microfluidic Monitoring Sensor Platform for Studying Autophagy Regulation after PM2.5 Exposure.

    Zheng, Lulu / Yang, Zhijin / Xue, Zhiwei / Chen, Mengya / Zhang, Yule / Cai, Shuqi / Zheng, Kejie / Dai, Bo / Liu, Sixiu / Zhuang, Songlin / Sui, Guodong / Zhang, Dawei

    ACS sensors

    2024  Volume 9, Issue 3, Page(s) 1178–1187

    Abstract: Undoubtedly, a deep understanding of ... ...

    Abstract Undoubtedly, a deep understanding of PM
    MeSH term(s) Humans ; RNA, Long Noncoding/genetics ; Microfluidics ; Lung Neoplasms/genetics ; Particulate Matter/toxicity ; Autophagy
    Chemical Substances RNA, Long Noncoding ; Particulate Matter
    Language English
    Publishing date 2024-03-04
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.3c01744
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  4. Article ; Online: Strong non-uniformity correction algorithm based on spectral shaping statistics and LMS.

    Liu, Tong / Sui, Xiubao / Wang, Yihong / Wang, Yu / Chen, Qian / Guan, Zhiwei / Chen, Xingliao

    Optics express

    2023  Volume 31, Issue 19, Page(s) 30693–30709

    Abstract: The existence of non-uniformity in infrared detector output images is a widespread problem that significantly degrades image quality. Existing scene-based non-uniformity correction algorithms typically struggle to balance strong non-uniformity correction ...

    Abstract The existence of non-uniformity in infrared detector output images is a widespread problem that significantly degrades image quality. Existing scene-based non-uniformity correction algorithms typically struggle to balance strong non-uniformity correction with scene adaptability. To address this issue, we propose a novel scene-based algorithm that leverages the frequency characteristics of the non-uniformity, combine and improve single-frame stripe removal, multi-scale statistics, and least mean square (LMS) methods. Following the "coarse-to-fine" correction process, the coarse correction stage introduces an adaptive progressive correction strategy based on Laplacian pyramids. By improving 1-D guided filtering and high-pass filtering to shape high-frequency sub-bands, non-uniformity can be well separated from the scene, effectively suppressing ghosting. In the fine correction stage, we optimize the expected image estimation and spatio-temporal adaptive learning rates based on guided filtering LMS method. To validate the efficacy of our algorithm, we conduct extensive simulation and real experiments, demonstrating its adaptability to various scene conditions and its effectiveness in correcting strong non-uniformity.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491859-6
    ISSN 1094-4087 ; 1094-4087
    ISSN (online) 1094-4087
    ISSN 1094-4087
    DOI 10.1364/OE.496398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Rapid and Multiplexed Detection of Single Cells of

    Wang, Ziquan / Wang, Meng / Xu, Qian / Liu, Siyuan / Gao, Ying / Chang, Haiyan / Sui, Zhiwei

    Foodborne pathogens and disease

    2022  Volume 19, Issue 4, Page(s) 272–280

    Abstract: ... ...

    Abstract Salmonella
    MeSH term(s) Animals ; Cattle ; Escherichia coli O157 ; Flow Cytometry ; Food Microbiology ; Meat Products/microbiology ; Salmonella ; Shigella flexneri
    Language English
    Publishing date 2022-03-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2148479-X
    ISSN 1556-7125 ; 1535-3141
    ISSN (online) 1556-7125
    ISSN 1535-3141
    DOI 10.1089/fpd.2021.0088
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    In stock of ZB MED Bonn / Germany

    Z 7517: Show issues

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  6. Article ; Online: Rapid Detection of Single Viable

    Wang, Ziquan / Liu, Siyuan / Zhen, Xiaoxiao / Li, Longquan / Zhou, Guoping / Wei, Qiang / Sui, Zhiwei

    Foodborne pathogens and disease

    2021  Volume 19, Issue 1, Page(s) 36–44

    Abstract: ... ...

    Abstract Enterohemorrhagic
    MeSH term(s) Colony Count, Microbial ; Escherichia coli O157 ; Flow Cytometry ; Food Microbiology ; Fragaria ; Immunomagnetic Separation ; Lactuca
    Language English
    Publishing date 2021-09-30
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2148479-X
    ISSN 1556-7125 ; 1535-3141
    ISSN (online) 1556-7125
    ISSN 1535-3141
    DOI 10.1089/fpd.2021.0031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 7517: Show issues

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  7. Article ; Online: Facilitating alkaline hydrogen evolution reaction on the hetero-interfaced Ru/RuO

    Zhu, Yiming / Klingenhof, Malte / Gao, Chenlong / Koketsu, Toshinari / Weiser, Gregor / Pi, Yecan / Liu, Shangheng / Sui, Lijun / Hou, Jingrong / Li, Jiayi / Jiang, Haomin / Xu, Limin / Huang, Wei-Hsiang / Pao, Chih-Wen / Yang, Menghao / Hu, Zhiwei / Strasser, Peter / Ma, Jiwei

    Nature communications

    2024  Volume 15, Issue 1, Page(s) 1447

    Abstract: Exploring an active and cost-effective electrocatalyst alternative to carbon-supported platinum nanoparticles for alkaline hydrogen evolution reaction (HER) have remained elusive to date. Here, we report a catalyst based on platinum single atoms (SAs) ... ...

    Abstract Exploring an active and cost-effective electrocatalyst alternative to carbon-supported platinum nanoparticles for alkaline hydrogen evolution reaction (HER) have remained elusive to date. Here, we report a catalyst based on platinum single atoms (SAs) doped into the hetero-interfaced Ru/RuO
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-024-45654-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Evaluation of volume-based flow cytometry as a potential primary method for quantification of bacterial reference material.

    Liu, Siyuan / Wang, Ziquan / Wang, Meng / Meng, Tao / Zhang, Yunzhe / Zhang, Wei / Sui, Zhiwei

    Talanta

    2022  Volume 255, Page(s) 124197

    Abstract: Bacterial reference materials (RMs) play a crucial role in many analytical processes of microbiological detection. Currently, bacteria are typically counted using the traditional plate-based approach, which results in a higher uncertainty of bacterial ... ...

    Abstract Bacterial reference materials (RMs) play a crucial role in many analytical processes of microbiological detection. Currently, bacteria are typically counted using the traditional plate-based approach, which results in a higher uncertainty of bacterial RMs unfortunately. Therefore, novel methods are urgently required for the value assignment of RMs in the field of microbiology to derive measurement traceability and accuracy. A potential primary method for microbiological quantification based on flow cytometry (FCM) is described in this study using Escherichia coli O157 (E. coli O157) as an example. The proposed method was applied to determine the number of viable E. coli O157 cells in the RMs with a result of (5.48 ± 0.27) × 10
    MeSH term(s) Food Microbiology ; Flow Cytometry/methods ; Bacteria ; Escherichia coli O157
    Language English
    Publishing date 2022-12-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2022.124197
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  9. Article ; Online: A Novel Strategy for Rapid Fluorescence Detection of FluB and SARS-CoV-2.

    Yang, Zhijin / Xue, Zhiwei / Zheng, Kejie / Zhang, Yule / Sui, Guorong / Yang, Haima / Zhuang, Songlin / Zheng, Lulu / Zhang, Dawei

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 5

    Abstract: Undoubtedly, SARS-CoV-2 has caused an outbreak of pneumonia that evolved into a worldwide pandemic. The confusion of early symptoms of the SARS-CoV-2 infection with other respiratory virus infections made it very difficult to block its spread, leading to ...

    Abstract Undoubtedly, SARS-CoV-2 has caused an outbreak of pneumonia that evolved into a worldwide pandemic. The confusion of early symptoms of the SARS-CoV-2 infection with other respiratory virus infections made it very difficult to block its spread, leading to the expansion of the outbreak and an unreasonable demand for medical resource allocation. The traditional immunochromatographic test strip (ICTS) can detect one analyte with one sample. Herein, this study presents a novel strategy for the simultaneous rapid detection of FluB/SARS-CoV-2, including quantum dot fluorescent microspheres (QDFM) ICTS and a supporting device. The ICTS could be applied to realize simultaneous detection of FluB and SARS-CoV-2 with one test in a short time. A device supporting FluB/SARS-CoV-2 QDFM ICTS was designed and had the characteristics of being safe, portable, low-cost, relatively stable, and easy to use, ensuring the device could replace the immunofluorescence analyzer in cases where there is no need for quantification. This device does not need to be operated by professional and technical personnel and has commercial application potential.
    MeSH term(s) Humans ; SARS-CoV-2 ; COVID-19 ; Limit of Detection ; Quantum Dots/chemistry
    Language English
    Publishing date 2023-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28052104
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    Zs.MO 81: Show issues

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  10. Article ; Online: Synthesis and biological activity assay of novel camptothecin-peptidic conjugates based on PEPT1.

    Zhang, Qiang / Zou, Ping / Zhu, Meixuan / Sui, Dan / Wang, Shaoming / Hu, Zhiwei / Wang, Yang / Jing, Lijia / Zheng, Jian

    Bioorganic & medicinal chemistry letters

    2023  Volume 96, Page(s) 129502

    Abstract: Camptothecin (CPT) and its derivatives are potent candidates for cancer treatment. However, the clinical applications are largely restricted by non-selectivity and severe toxicities. The peptide transporter 1 (PEPT1), which is highly expressed in human ... ...

    Abstract Camptothecin (CPT) and its derivatives are potent candidates for cancer treatment. However, the clinical applications are largely restricted by non-selectivity and severe toxicities. The peptide transporter 1 (PEPT1), which is highly expressed in human intestines, has been found to be overexpressed in several cancer cells. This discovery suggests that PEPT1 has the potential to serve as a therapeutic target for both improving bioavailability and cancer-targeting treatment. Therefore, a prodrug approach for CPT targeting at PEPT1 highly expressed cancer cells was adopted in the present study. Eighteen CPT prodrugs, its peptidic conjugates, were synthesized and the structures were confirmed by NMR and HRMS. The protein expression profiles of PEPT1 in different cell lines were performed using immunofluorescence assay and western blotting analysis. The cytotoxicity of CPT prodrugs and their uptake via competition with Gly-Sar, a typical substrate of PEPT1, were evaluated in both PEPT1-overexpressed and under expressed cells. The results demonstrated that most CPT prodrugs significantly impaired Gly-Sar uptake, suggesting a higher affinity of CPT-peptidic conjugates for PEPT1 and PEPT1 overexpression cells. In addition, these prodrugs demonstrated a higher capability for inhibiting cell growth in PEPT1 highly-expressed cancer cells compared to PEPT1 under expressed cells. These results indicated that this peptidic prodrug strategy might offer great potential for improved tumor selectivity and chemotherapeutic efficacy of CPT.
    MeSH term(s) Humans ; Prodrugs/chemistry ; Peptide Transporter 1/metabolism ; Cell Line ; Biological Transport ; Neoplasms ; Camptothecin/pharmacology ; Camptothecin/chemistry
    Chemical Substances Prodrugs ; Peptide Transporter 1 ; Camptothecin (XT3Z54Z28A)
    Language English
    Publishing date 2023-10-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1063195-1
    ISSN 1464-3405 ; 0960-894X
    ISSN (online) 1464-3405
    ISSN 0960-894X
    DOI 10.1016/j.bmcl.2023.129502
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3203: Show issues Location:
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