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  1. Article ; Online: Evaluation model and promotion based on the ecological characteristics of Saihanba

    Wang Bingqi

    E3S Web of Conferences, Vol 375, p

    2023  Volume 03013

    Abstract: Saihanba Mechanical Forest Farm is an important sand source control project area in China. In order to promote the excellent case of Saihanba to other regions of the country and even the Asia-Pacific region, we have established a Saihanba ecological ... ...

    Abstract Saihanba Mechanical Forest Farm is an important sand source control project area in China. In order to promote the excellent case of Saihanba to other regions of the country and even the Asia-Pacific region, we have established a Saihanba ecological environmental impact model and ecological engineering construction assessment model, to provide suggestions for the establishment of ecological protection areas in China and even countries in the Asia-Pacific region. This paper determined the index of Saihanba ecological influence evaluation system using frequency analysis method and theoretical research method, determined the TOPSIS weight based on entropy weight method, to establish a complete ecological and environmental influence evaluation system. Subsequently, the paper introduced the data of relevant indicators around 1962 into the evaluation system, which got good scores, indicating that Saihanba has a great positive impact on the ecological environment. On the basis of problem 1, this paper had redefined the index and weight, established the index system based on the sandstorm background in Beijing, and brought the relevant data of Beijing in recent years into the model, and the establishment of Saihanba had played a relatively significant optimization effect on all the indicators of the sandstorm in Beijing. In view of problem 3, this article was first divided into 9 different ecological system service functional zones according to the National ecological function zoning (revised version) proposed by the Ministry of Environmental Protection and the Chinese Academy of Sciences. Meanwhile, based on the TOPSIS model, proposed a modified model based on DPSIR. The model fully omitted the impact of ecological, economic, policy and other factors on the construction of ecological protection areas .Meanwhile, multi-objective planning method based on genetic algorithm was used to solve the above problems to determine the best number and scale of ecological reserves in the region.
    Keywords entropy power method topsis principal component analysis genetic algorithm multi-objective planning bp neural network dpsir ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: SELPLG Expression Was Potentially Correlated With Metastasis and Prognosis of Osteosarcoma.

    Wang, Bingqi / Sun, Yufu

    Pathology oncology research : POR

    2022  Volume 28, Page(s) 1610047

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Biomarkers, Tumor/metabolism ; Bone Neoplasms/pathology ; Humans ; Membrane Glycoproteins/analysis ; Membrane Glycoproteins/biosynthesis ; Osteosarcoma/pathology ; Prognosis
    Chemical Substances Biomarkers, Tumor ; Membrane Glycoproteins ; P-selectin ligand protein
    Language English
    Publishing date 2022-01-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1375979-6
    ISSN 1532-2807 ; 1219-4956
    ISSN (online) 1532-2807
    ISSN 1219-4956
    DOI 10.3389/pore.2022.1610047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pathogenesis or a response to lithium? A novel perspective for mitochondrial mass fluctuation of naïve T cells in patients with bipolar disorder.

    Chen, Zhenni / Wang, Bingqi / Huang, Yiran / Wang, Xiaofan / Li, Wanzhen / Wang, Min

    Journal of affective disorders

    2024  Volume 355, Page(s) 86–94

    Abstract: Background: Immune imbalances are associated with the pathogenesis and pharmacological efficacy of bipolar disorder (BD). The underlying mechanisms remain largely obscure but may involve immunometabolic dysfunctions of T-lymphocytes.: Methods: We ... ...

    Abstract Background: Immune imbalances are associated with the pathogenesis and pharmacological efficacy of bipolar disorder (BD). The underlying mechanisms remain largely obscure but may involve immunometabolic dysfunctions of T-lymphocytes.
    Methods: We investigated if inflammatory cytokines and the immunometabolic function of T-lymphocytes, including frequencies of subsets, mitochondrial mass (MM), and low mitochondrial membrane potential (MMP
    Results: In comparison to HC, BD patients predominantly showed a trend toward CD4
    Limitations: The cross-sectional design and short-term follow-up meant that we could not directly examine the causality of BD and immune dysregulation.
    Conclusion: The altered metabolism of CD4
    MeSH term(s) Humans ; Bipolar Disorder/genetics ; Lithium/pharmacology ; Lithium/therapeutic use ; CD8-Positive T-Lymphocytes/metabolism ; Cross-Sectional Studies ; Mitochondria/metabolism ; Lithium Compounds/therapeutic use ; Lithium Compounds/pharmacology
    Chemical Substances Lithium (9FN79X2M3F) ; Lithium Compounds
    Language English
    Publishing date 2024-03-21
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 135449-8
    ISSN 1573-2517 ; 0165-0327
    ISSN (online) 1573-2517
    ISSN 0165-0327
    DOI 10.1016/j.jad.2024.03.095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Atlas of the Inferior Mesenteric Artery and Vein under Maximum-Intensity Projection and Three-Dimensional Reconstruction View.

    Zhang, Hongwei / Liu, Shurong / Dong, Bingqi / Liu, Jing / Guo, Xiaochao / Chen, Guowei / Jiang, Yong / Wu, Yingchao / Zhang, Junling / Wang, Xin

    Journal of clinical medicine

    2024  Volume 13, Issue 3

    Abstract: 1) ...

    Abstract (1)
    Language English
    Publishing date 2024-02-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13030879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Relationship between circulating metabolites and diabetic retinopathy: a two-sample Mendelian randomization analysis.

    Ma, Lingli / Dong, Ying / Li, Zimeng / Meng, Jian / Zhao, Bingqi / Wang, Qing

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 4964

    Abstract: Diabetic retinopathy (DR) is the most frequent microvascular complication of diabetes mellitus, however, its underlying biological mechanisms remain poorly understood. We examined single nucleotide polymorphisms linked to 486 blood metabolites through ... ...

    Abstract Diabetic retinopathy (DR) is the most frequent microvascular complication of diabetes mellitus, however, its underlying biological mechanisms remain poorly understood. We examined single nucleotide polymorphisms linked to 486 blood metabolites through extensive genome-wide association studies conducted on individuals of European ancestry. The FinnGen Biobank database served as a reference to define DR. Two-sample MR analysis was conducted to reveal the association between the levels of genetically predicted circulating metabolites and the susceptibility to DR. To validate the robustness of the obtained findings, sensitivity analyses with weighted median, weighted mode, and MR-Egger were conducted. 1-oleoylglycerophosphoethanolamine (odds ratio [OR] (OR per one standard deviation [SD] increase) = 0.414; 95% confidence interval [CI] 0.292-0.587; P = 7.613E-07, P
    MeSH term(s) Humans ; Diabetic Retinopathy/genetics ; Genome-Wide Association Study ; Mendelian Randomization Analysis ; Prospective Studies ; Databases, Factual ; Diabetes Mellitus
    Language English
    Publishing date 2024-02-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55704-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Bioinformatics and Network Pharmacology Explore the Role of Immune Cells in the Occurrence of Anti-Vascular Endothelial Growth Factor (VEGF) Resistance in Patients with Neovascular Age-Related Macular Degeneration(nAMD) and the Application of Complementary Medicine Treatment.

    Wang, Mingyan / Li, Hongwei / Wu, Yan / Wang, Bingqi / Xi, Ya / Hu, Kaifeng

    Ocular immunology and inflammation

    2024  , Page(s) 1–16

    Abstract: Purpose: This study explores the immune cells' role in anti-VEGF resistance in nAMD patients, and the potential of Zi-Yin-Jiang-Huo-Tang (ZYJHT), a Traditional Chinese Medicine formula, as complementary therapy.: Methods: Aqueous humor proteomics ... ...

    Abstract Purpose: This study explores the immune cells' role in anti-VEGF resistance in nAMD patients, and the potential of Zi-Yin-Jiang-Huo-Tang (ZYJHT), a Traditional Chinese Medicine formula, as complementary therapy.
    Methods: Aqueous humor proteomics data from 10 nAMD patients with anti-VEGF resistance and 10 nAMD patients without anti-VEGF resistance were analyzed, investigating immune cells's role in anti-VEGF resistance and its underlying mechanism. Network pharmacology methods are employed to analyze the active ingredients in ZYJHT that contribute to therapeutic effects and their mechanisms. Real-time PCR (polymerase chain reaction) was used to detect changes in the expression of SOD1 (superoxide dismutase 1) after treatment with compounds targeting SOD1 in ARPE-19 cells.
    Results: nAMD patients with anti-VEGF resistance showed enhancement of biological processes linked to the positive regulation of immune function, along with decreased cellular resistance to oxidative stress. Infiltration of B cells memory, plasma cells, CD8
    Language English
    Publishing date 2024-01-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1193873-0
    ISSN 1744-5078 ; 0927-3948
    ISSN (online) 1744-5078
    ISSN 0927-3948
    DOI 10.1080/09273948.2024.2306129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Clinical and prognostic significance of CCPG1 in hepatocellular carcinoma.

    Wang, Gangpu / Liu, Zhiqian / Wang, Qi / Liu, Bingqi / Li, Jie

    General physiology and biophysics

    2023  Volume 42, Issue 5, Page(s) 431–442

    Abstract: This study aimed to examine the clinical and prognostic significance of cell-cycle progression gene 1 (CCPG1) in hepatocellular carcinoma (HCC). We firstly analyzed CCPG1 expression in various cancers using The Cancer Genome Atlas and the Genotype-Tissue ...

    Abstract This study aimed to examine the clinical and prognostic significance of cell-cycle progression gene 1 (CCPG1) in hepatocellular carcinoma (HCC). We firstly analyzed CCPG1 expression in various cancers using The Cancer Genome Atlas and the Genotype-Tissue Expression project databases. The relative expression levels of CCPG1 were determined in 164 paired HCC and adjacent tissues using immunohistochemistry. The correlation between CCPG1 and clinicopathological characteristics of HCC was analyzed. Cox proportional models were used to identify the prognostic factors for overall survival (OS) and disease-free survival (DFS). The expression of CCPG1 was lower in HCC tissues than in adjacent non-tumor liver tissues. The expression of CCPG1 was significantly correlated with tumor number (p = 0.02) and tumor differentiation (p = 0.04) in HCC. Lower expression of CCPG1 in HCC patients was associated with poor OS and DFS (p < 0.01). Relative low expression of CCPG1 in HCC is significantly correlated with the poor prognosis of HCC patients after surgical resection, suggesting its possible role as a potential prognostic marker for HCC.
    MeSH term(s) Humans ; Carcinoma, Hepatocellular/diagnosis ; Cell Differentiation ; Liver Neoplasms/diagnosis ; Prognosis
    Chemical Substances CCPG1 protein, human
    Language English
    Publishing date 2023-09-13
    Publishing country Slovakia
    Document type Journal Article
    ZDB-ID 791184-1
    ISSN 0231-5882
    ISSN 0231-5882
    DOI 10.4149/gpb_2023017
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Study on the Kinetics of Hydration Transformation from Hemihydrate Phosphogypsum to Dihydrate Phosphogypsum in Simulated Wet Process Phosphoric Acid

    Bingqi Wang / Lin Yang / Tong Luo / Jianxin Cao

    ACS Omega, Vol 6, Iss 11, Pp 7342-

    2021  Volume 7350

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Hybrid Aerogel Triboelectric Nanogenerator Based on the Synergistic Effect of Solid-Solid/Gas-Solid Triboelectricity and Piezoelectric Polarization.

    Huang, Tianci / Long, Yong / Zhao, Bingqi / Hua, Qilin / Wang, Zhong Lin / Hu, Weiguo

    ACS applied materials & interfaces

    2023  Volume 15, Issue 22, Page(s) 26682–26690

    Abstract: Aerogels, due to their unique interconnected 3D networks, and large number of air-filled pores, extend the structural characteristics and physicochemical properties of the nanoscale to the macro level. However, aerogels made from a single component can ... ...

    Abstract Aerogels, due to their unique interconnected 3D networks, and large number of air-filled pores, extend the structural characteristics and physicochemical properties of the nanoscale to the macro level. However, aerogels made from a single component can hardly meet the needs of multifunctional energy harvesting/supply situations. Here, a BaTiO
    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Journal Article
    ISSN 1944-8252
    ISSN (online) 1944-8252
    DOI 10.1021/acsami.3c02969
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: TYR mutation in a Chinese population with oculocutaneous albinism: Molecular characteristics and ophthalmic manifestations.

    Chen, Chonglin / Li, Jun / Wang, Bingqi / Wang, Yinghuan / Yu, Xinping

    Experimental eye research

    2023  Volume 239, Page(s) 109761

    Abstract: Oculocutaneous albinism (OCA) is a rare inherited disorder characterized by a partial or complete reduction of melanin biosynthesis that leads to hypopigmentation in the skin, hair and eyes. The OCA1 subtype is caused by mutations in TYR. The purpose of ... ...

    Abstract Oculocutaneous albinism (OCA) is a rare inherited disorder characterized by a partial or complete reduction of melanin biosynthesis that leads to hypopigmentation in the skin, hair and eyes. The OCA1 subtype is caused by mutations in TYR. The purpose of this study was to investigate the genetic and clinical ophthalmic characteristics of TYR mutations in patients with OCA. Herein, 51 probands with a clinical diagnosis of OCA were enrolled. Whole-exome sequencing and comprehensive ophthalmic examinations were performed. Overall, TYR mutations were detected in 37.3% (19/51) in the patients with OCA. Fifteen patients had compound heterozygous variants, and four cases had homozygous variants. Eleven different pathogenic variants in TYR were detected in these 19 patients, with missense, insertion, delins and nonsense in 71.1% (27/38), 15.8% (6/38), 2.6% (1/38), and 10.5% (4/38), respectively. Clinical examinations revealed that 84.2% (16/19) of patients were OCA1A, and 15.8% (3/19) were OCA1B. Most TYR probands (52.6%, 10/19) had moderate vision impairment, 15.8% (3/19) had severe visual impairment, 10.5% (2/19) exhibited blindness, only 5.3% (1/19) had mild visual impairment and 15.8% (3/19) were not available. Photophobia and nystagmus were found in 100% (19/19) of the patients. In addition, grade 4 foveal hypoplasia was detected in 100% (12/12) of the patients. In conclusion: The TYR patients exhibited severe ocular phenotypes: the majority (93.8%, 15/16) of them had a moderate vision impairment or worse, and 100% (12/12) had severe grade 4 foveal hypoplasia. These novel findings could provide insight into the understanding of OCA.
    MeSH term(s) Humans ; Albinism, Oculocutaneous/genetics ; Albinism, Oculocutaneous/diagnosis ; Albinism, Oculocutaneous/epidemiology ; Mutation ; Retina ; Monophenol Monooxygenase/genetics ; Vision Disorders ; China/epidemiology
    Chemical Substances Monophenol Monooxygenase (EC 1.14.18.1)
    Language English
    Publishing date 2023-12-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 80122-7
    ISSN 1096-0007 ; 0014-4835
    ISSN (online) 1096-0007
    ISSN 0014-4835
    DOI 10.1016/j.exer.2023.109761
    Database MEDical Literature Analysis and Retrieval System OnLINE

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