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Article: Developing a digital archive system for imperial Chinese robe in the Qing Dynasty.

Su, Miao / Li, Saiquan / Lu, Yan / Yang, Limei / Duan, Yiting / Xiao, Kaida / Pointer, Michael / Luo, Ming Ronnier / Liu, Xiaoxuan

Frontiers in neuroscience

2022 Volume 16, Page(s) 971169

Abstract: ... to achieve accurate color reproduction. Taking the Imperial Chinese robes in the Qing Dynasty as an example ...

Abstract	The digital archive of cultural heritage provides new opportunities for the protection of the cultural heritage and the development of online museums. One of the essential requirements for the digitization is to achieve accurate color reproduction. Taking the Imperial Chinese robes in the Qing Dynasty as an example, this study aims to develop a digital achieve system to digitize the robes using a high-end imaging system and accurately reproduce their color properties on a display. Currently, there has been very limited study focused on the color reproduction of silk fabrics or other textile materials. The conventional color management process using a traditional color chart, however, may not be suitable for the reproduction of silk fabrics because they have very high gloss. To address this difficulty, a unique "Qianlong Palette" color chart, consisting of 210 silk fabric samples, has been specifically produced for optimizing the color reproduction of silk fabrics and a color image reproduction system has been developed for the digitization and archiving of the clothing fabric for the royal court. Color characterization models using both the "Qianlong Palette" color chart and the traditional color chart, and different mapping methods, are compared and the model with highest accuracy used in a self-programmed interface for automatically processing textile images in the future. Finally, the digital archive system has been validated using six garments of silk fabric relics. The color differences after the color image reproduction are all less than 3.00ΔE*
Language	English
Publishing date	2022-07-28
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2411902-7
ISSN	1662-453X ; 1662-4548
ISSN (online)	1662-453X
ISSN	1662-4548
DOI	10.3389/fnins.2022.971169
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effect and mechanism of Qing Gan Zi Shen decoction on heart damage induced by obesity and hypertension.

Zhang, Shujie / Liu, Zitian / Zhang, Han / Zhou, Xiaonian / Wang, Xiuming / Chen, Yan / Miao, Xiaofan / Zhu, Yao / Jiang, Weimin

Journal of ethnopharmacology

2023 Volume 319, Issue Pt 2, Page(s) 117163

Abstract: Ethnopharmacological relevance: Qing Gan Zi Shen Decoction (QGZS) is a traditional Chinese formula ...

Abstract	Ethnopharmacological relevance: Qing Gan Zi Shen Decoction (QGZS) is a traditional Chinese formula. It has been extensively used for decades in the treatment of hypertension combined with metabolic diseases, but its cardioprotective effects and underlying mechanisms are poorly understood. Aim of the study: To explore the cardioprotective effects and potential mechanisms of QGZS in an animal model of obese hypertension. Materials and methods: In this study, spontaneously hypertensive rats (SHRs) were utilized as an animal model to examine the effects of a high-fat diet and two concentrations of QGZS. Echocardiography, hematoxylin eosin (H&E) staining, and wheat germ agglutinin (WGA) staining were employed to assess the cardiac structure and function of the SHRs throughout a 16-week therapy period. Furthermore, Western blotting (WB) and immunofluorescence (IF) were employed to identify the levels of Nrf2 expression in the mitochondria, cytoplasm, and nucleus of the myocardium. Additionally, transmission electron microscopy and enzyme-linked immunosorbent assay (ELISA) were utilized to measure mitochondrial morphology and pro-inflammatory cytokine levels, respectively. Furthermore, Western blotting (WB), immunohistochemistry (IHC), and immunofluorescence (IF) techniques were employed to quantify the levels of marker proteins associated with myocardial fibrosis, cardiac inflammation, oxidative stress, and mitochondrial dysfunction. Results: QGZS inhibited weight gain and depressed systolic and mean arterial pressures in high-fat-fed SHRs. Echocardiographic results demonstrated that QGZS prevented the increase in left ventricular mass, restricted the growth of left ventricular diameter, and improved ejection fraction (EF), fractional shortening (FS), and the ratio of early diastolic peak velocity of transmitral flow (E) to late diastolic peak velocity (A) in high-fat-fed SHRs. This suggested that QGZS prevented ventricular remodeling and protected cardiac systolic and diastolic functions. H&E and WGA staining showed that QGZS improved cardiomyocyte disorders and restricted cardiomyocyte hypertrophy. The underlying mechanisms, QGZS attenuated the oxidative stress state, including reducing the generation of reactive oxygen species (ROS) in the myocardium, revitalizing the antioxidant enzyme system, and protecting mitochondrial function. Moreover, QGZS alleviated the pro-inflammatory state in high-fat-fed SHRs. What's more, QGZS significantly increased the expression level of Nrf2 in nuclei and mitochondria in rat heart tissues, exerting a proximate Nrf2 agonist effect. Conclusions: QGZS exerted cardioprotective effects, in part due to its increasing expression of Nrf2 protein in the heart, which promoted Nrf2 nuclear expression.
MeSH term(s)	Rats ; Animals ; NF-E2-Related Factor 2/metabolism ; Obesity/metabolism ; Myocardium/metabolism ; Hypertension/drug therapy ; Hypertension/metabolism ; Rats, Inbred SHR ; Heart Injuries/metabolism
Chemical Substances	NF-E2-Related Factor 2
Language	English
Publishing date	2023-09-21
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2023.117163
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Zs.A 1494: Show issues

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Article ; Online: Xin-Yi-Qing-Fei-Tang and its critical components reduce asthma symptoms by suppressing GM-CSF and COX-2 expression in RBL-2H3 cells.

Wang, Shulhn-Der / Chen, Po-Ting / Hsieh, Miao-Hsi / Wang, Jiu-Yao / Chiang, Chung-Jen / Lin, Li-Jen

Journal of ethnopharmacology

2024 Volume 330, Page(s) 118105

Abstract: Ethnopharmacological relevance: The traditional Chinese medicine (TCM) XYQFT is composed of 10 herbs. According to the NHIRD, XYQFT is one of the top ten most commonly used TCM prescriptions for asthma treatment.: Aim of the study: The aim of this ... ...

Abstract	Ethnopharmacological relevance: The traditional Chinese medicine (TCM) XYQFT is composed of 10 herbs. According to the NHIRD, XYQFT is one of the top ten most commonly used TCM prescriptions for asthma treatment. Aim of the study: The aim of this study was to explore whether XYQFT reduces asthma symptoms in a mouse model of chronic asthma and determine the immunomodulatory mechanism of mast cells. Materials and methods: BALB/c mice were intratracheally (it) stimulated with 40 μL (2.5 μg/μL) of Dermatophagoides pteronyssinus (Der p) once a week for 6 consecutive weeks and orally administered XYQFT at 1 g/kg 30 min before Der p stimulation. Airway hypersensitivity, inflammatory cells in the BALF and total IgE in the blood were assessed in mice. In addition, RBL-2H3 cells (mast cells) were stimulated with DNP-IgE, after which different concentrations of XYQFT were added for 30 min to evaluate the effect of XYQFT on the gene expression and degranulation of DNP-stimulated RBL-2H3 cells. After the compounds in XYQFT were identified using LC‒MS/MS, the PBD method was used to identify the chemical components that inhibited the expression of the GM-CSF and COX-2 genes in mast cells. Results: The airway hypersensitivity assay demonstrated that XYQFT significantly alleviated Der p-induced airway hypersensitivity. Moreover, cell counting and typing of bronchoalveolar lavage fluid revealed a significant reduction in Der p-induced inflammatory cell infiltration with XYQFT treatment. ELISA examination further indicated a significant decrease in Der p-induced total IgE levels in serum following XYQFT administration. In addition, XYQFT inhibited the degranulation and expression of genes (IL-3, IL-4, ALOX-5, IL-13, GM-CSF, COX-2, TNF-α, and MCP-1) in RBL-2H3 cells after DNP stimulation. The compounds timosaponin AIII and genkwanin in XYQFT were found to be key factors in the inhibition of COX-2 and GM-CSF gene expression in mast cells. Conclusion: By regulating mast cells, XYQFT inhibited inflammatory cell infiltration, airway hypersensitivity and specific immunity in a mouse model of asthma. In addition, XYQFT synergistically inhibited the expression of the GM-CSF and COX-2 genes in mast cells through timosaponin AIII and genkwanin.
Language	English
Publishing date	2024-04-16
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2024.118105
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Article ; Online: Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs.

Zhong, Linda Li Dan / Lam, Wai Ching / Yang, Wei / Chan, Kam Wa / Sze, Stephen Cho Wing / Miao, Jiangxia / Yung, Ken Kin Lam / Bian, Zhaoxiang / Wong, Vivian Taam

The American journal of Chinese medicine

2020 Volume 48, Issue 5, Page(s) 1051–1071

Abstract: ... to identify more therapeutics such as Chinese medicine formulae to meet the urgent need. Qing Fei Pai Du Tang ...

Abstract	COVID-19 has been declared a pandemic by WHO on March 11, 2020. No specific treatment and vaccine with documented safety and efficacy for the disease have been established. Hence it is of utmost importance to identify more therapeutics such as Chinese medicine formulae to meet the urgent need. Qing Fei Pai Du Tang (QFPDT), a Chinese medicine formula consisting of 21 herbs from five classical formulae has been reported to be efficacious on COVID-19 in 10 provinces in mainland China. QFPDT could prevent the progression from mild cases and shorten the average duration of symptoms and hospital stay. It has been recommended in the 6th and 7th versions of Clinical Practice Guideline on COVID-19 in China. The basic scientific studies, supported by network pharmacology, on the possible therapeutic targets of QFPDT and its constituent herbs including
MeSH term(s)	Animals ; Antiviral Agents/administration & dosage ; Antiviral Agents/history ; Betacoronavirus/drug effects ; Betacoronavirus/physiology ; COVID-19 ; China ; Coronavirus Infections/drug therapy ; Coronavirus Infections/virology ; Drugs, Chinese Herbal/administration & dosage ; Drugs, Chinese Herbal/history ; History, Ancient ; Humans ; Medicine in Literature ; Medicine, Chinese Traditional ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/virology ; SARS-CoV-2
Chemical Substances	Antiviral Agents ; Drugs, Chinese Herbal
Keywords	covid19
Language	English
Publishing date	2020-05-07
Publishing country	Singapore
Document type	Historical Article ; Journal Article ; Review
ZDB-ID	193085-0
ISSN	1793-6853 ; 0090-2942 ; 0192-415X
ISSN (online)	1793-6853
ISSN	0090-2942 ; 0192-415X
DOI	10.1142/S0192415X20500512
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Article ; Online: Comprehensive profiling and characterization of the absorbed components and metabolites in mice serum and tissues following oral administration of Qing-Fei-Pai-Du decoction by UHPLC-Q-Exactive-Orbitrap HRMS.

Liu, Wei / Huang, Jian / Zhang, Feng / Zhang, Cong-Cong / Li, Rong-Sheng / Wang, Yong-Li / Wang, Chao-Ran / Liang, Xin-Miao / Zhang, Wei-Dong / Yang, Ling / Liu, Ping / Ge, Guang-Bo

Chinese journal of natural medicines

2021 Volume 19, Issue 4, Page(s) 305–320

Abstract: Qing-Fei-Pai-Du decoction (QFPDD) is a Chinese medicine compound formula recommended for combating ...

Abstract	Qing-Fei-Pai-Du decoction (QFPDD) is a Chinese medicine compound formula recommended for combating corona virus disease 2019 (COVID-19) by National Health Commission of the People's Republic of China. The latest clinical study showed that early treatment with QFPDD was associated with favorable outcomes for patient recovery, viral shedding, hospital stay, and course of the disease. However, the effective constituents of QFPDD remain unclear. In this study, an UHPLC-Q-Orbitrap HRMS based method was developed to identify the chemical constituents in QFPDD and the absorbed prototypes as well as the metabolites in mice serum and tissues following oral administration of QFPDD. A total of 405 chemicals, including 40 kinds of alkaloids, 162 kinds of flavonoids, 44 kinds of organic acids, 71 kinds of triterpene saponins and 88 kinds of other compounds in the water extract of QFPDD were tentatively identified via comparison with the retention times and MS/MS spectra of the standards or refereed by literature. With the help of the standards and in vitro metabolites, 195 chemical components (including 104 prototypes and 91 metabolites) were identified in mice serum after oral administration of QFPDD. In addition, 165, 177, 112, 120, 44, 53 constituents were identified in the lung, liver, heart, kidney, brain, and spleen of QFPDD-treated mice, respectively. These findings provided key information and guidance for further investigation on the pharmacologically active substances and clinical applications of QFPDD.
MeSH term(s)	Administration, Oral ; Alkaloids/analysis ; Animals ; COVID-19 ; Chromatography, High Pressure Liquid ; Drugs, Chinese Herbal/chemistry ; Drugs, Chinese Herbal/pharmacokinetics ; Flavonoids/analysis ; Mice ; SARS-CoV-2 ; Saponins/analysis ; Triterpenes/analysis
Chemical Substances	Alkaloids ; Drugs, Chinese Herbal ; Flavonoids ; Saponins ; Triterpenes
Language	English
Publishing date	2021-03-13
Publishing country	China
Document type	Journal Article
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(21)60031-6
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Article: Potential Targets for Treatment of Coronavirus Disease 2019 (COVID-19): A Review of Qing-Fei-Pai-Du-Tang and Its Major Herbs

Zhong, Linda Li Dan / Lam, Wai Ching / Yang, Wei / Chan, Kam Wa / Sze, Stephen Cho Wing / Miao, Jiangxia / Yung, Ken Kin Lam / Bian, Zhaoxiang / Wong, Vivian Taam

Am J Chin Med

Abstract: ... to identify more therapeutics such as Chinese medicine formulae to meet the urgent need. Qing Fei Pai Du Tang ...

Abstract	COVID-19 has been declared a pandemic by WHO on March 11, 2020. No specific treatment and vaccine with documented safety and efficacy for the disease have been established. Hence it is of utmost importance to identify more therapeutics such as Chinese medicine formulae to meet the urgent need. Qing Fei Pai Du Tang (QFPDT), a Chinese medicine formula consisting of 21 herbs from five classical formulae has been reported to be efficacious on COVID-19 in 10 provinces in mainland China. QFPDT could prevent the progression from mild cases and shorten the average duration of symptoms and hospital stay. It has been recommended in the 6th and 7th versions of Clinical Practice Guideline on COVID-19 in China. The basic scientific studies, supported by network pharmacology, on the possible therapeutic targets of QFPDT and its constituent herbs including Ephedra sinica, Bupleurum chinense, Pogostemon cablin, Cinnamomum cassia, Scutellaria baicalensis were reviewed. The anti-oxidation, immuno-modulation and antiviral mechanisms through different pathways were collated. Two clusters of actions identified were cytokine storm prevention and angiotensin converting enzyme 2 (ACE2) receptor binding regulation. The multi-target mechanisms of QFPDT for treating viral infection in general and COVID-19 in particular were validated. While large scale clinical studies on QFPDT are being conducted in China, one should use real world data for exploration of integrative treatment with inclusion of pharmacokinetic, pharmacodynamic and herb-drug interaction studies.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #647145
Database	COVID19

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Article: Comment on “An equable subtropical climate throughout China in the Miocene based on palaeofloral evidence” by Qing Wang, Yan Li David K. Ferguson, Wen-Bo Mo, and Nan Yang, Earth-Science Reviews, [Earth-Science Reviews 218 (2021) 103649]

Miao, Yunfa / Xiang, Mingxing / Zhang, Teng / Warny, Sophie

Elsevier B.V. Earth-science reviews. 2022 Mar. 29,

2022

Abstract: ... based on palaeofloral evidence”, Qing Wang, Yan Li, David K. Ferguson, Wen-Bo Mo, and Nan Yang (2021 ...

Abstract	In their thoughtful paper entitled “An equable subtropical climate throughout China in the Miocene based on palaeofloral evidence”, Qing Wang, Yan Li, David K. Ferguson, Wen-Bo Mo, and Nan Yang (2021) imply that China exhibited negligible latitudinal mean annual precipitation (MAP) gradients and lacked arid regions during the Miocene. They also speculate that there was no abrupt change in elevation of the Tibetan Plateau, nor that the plateau attained its present altitude or orography during that period. These conclusions were derived mainly by using a co-existence approach (CA) and ‘incomplete data’. Here, we use CA with training data and also integrate a coexistence likelihood estimation, a pollen-MAP boundary, a desert-MAP boundary, and other newly published MAP data to show that Northwest China consistently exhibited drier conditions than South China and East China during the entire Miocene, with our new values being 300–500 mm lower than those of Wang et al. (2021). This implies that there were large spatial gradients of MAP in China during the Miocene, which may be directly linked with the growth of the Tibetan Plateau, the global cooling, as well as other factors. We recommend the comprehensive consideration of multiple methods and proxies for reconstructing past climate conditions as opposed to a single proxy.
Keywords	Miocene epoch ; altitude ; atmospheric precipitation ; global cooling ; paper ; subtropics ; China
Language	English
Dates of publication	2022-0329
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ZDB-ID	1792-9
ISSN	0012-8252
ISSN	0012-8252
DOI	10.1016/j.earscirev.2022.104020
Database	NAL-Catalogue (AGRICOLA)

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Article: Qing-Re-Xing-Yu decoction confers intestinal barrier protection by reducing epithelial cell pyroptosis in experimental ulcerative colitis based on a NLRP3-GSDMD axis-dependent mechanism

Yan, Jing / Cao, Tingting / Ye, Ningyuan / Ye, Bai / Xu, Yi / Lu, Weimin / Xu, Danhua / Tan, Chang / Ning, Liqin / Miao, Zhiwei

Phytomedicine. 2021 Aug. 20,

2021

Abstract: ... mechanistic actions of Qing-Re-Xing-Yu (QRXY) decoction on the intestinal barrier dysfunction of UC.UC was ...

Abstract	Ulcerative colitis (UC) is a chronic inflammatory disease afflicting the colon, showing a rising incidence worldwide. Chinese medicinal formulae have been identified to be effective for the clinical treatment of UC yet the underlying mechanism remains under-studied.We herein investigate the molecular mechanistic actions of Qing-Re-Xing-Yu (QRXY) decoction on the intestinal barrier dysfunction of UC.UC was induced in C57BL/6 mice by adding 3% dextran sulfate sodium (DSS) in the drinking water. Following this, the mice were administrated with QRXY decoction. Clinical symptoms were assessed, followed by determining the expression of NACHT, LRR, and PYD domains-containing protein 3 (NLRP3), inflammatory cytokines, Caco-2 cell viability, pyroptosis and permeability along with the lactate dehydrogenase (LDH) release in DSS-induced UC mice and NLRP3- or Gasdermin-D (GSDMD)-knockout Caco-2 cells. The GSDMD-overexpressing mouse model was constructed using the adeno-associated virus type 2 (AAV2) to examine its involvement in the role of QRXY in UC.QRXY decoction alleviated the DSS-induced intestinal mucosal damage in mice with UC. This effect of QRXY was associated with the downregulated activity of NLRP3 inflammasome. Mechanistic investigations showed that QRXY decoction impaired the DSS-induced Caco-2 cell pyroptosis and permeability in vitro by inhibiting the NLRP3-GSDMD signaling axis. Moreover, GSDMD overexpression attenuated the protective role of QRXY decoction in the intestinal barrier dysfunction.Our study reveals that QRXY decoction restores intestinal barrier function via a NLRP3-GSDMD feedback loop, suggesting that NLRP3-GSDMD signaling inhibitor may serve as a adjuvant agent for UC, providing novel insight into the clinical application of QRXY decoction with better efficiency and smaller side effect.
Keywords	Dependoparvovirus ; adjuvants ; adverse effects ; cell viability ; colon ; cytokines ; dextran sulfate ; epithelial cells ; human cell lines ; inflammasomes ; lactate dehydrogenase ; mice ; permeability ; protective effect ; pyroptosis ; ulcerative colitis
Language	English
Dates of publication	2021-0820
Publishing place	Elsevier GmbH
Document type	Article
Note	Pre-press version
ZDB-ID	1205240-1
ISSN	1618-095X ; 0944-7113
ISSN (online)	1618-095X
ISSN	0944-7113
DOI	10.1016/j.phymed.2021.153725
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Article: Comprehensive profiling and characterization of the absorbed components and metabolites in mice serum and tissues following oral administration of Qing-Fei-Pai-Du decoction by UHPLC-Q-Exactive-Orbitrap HRMS

LIU, Wei / HUANG, Jian / ZHANG, Feng / ZHANG, Cong-Cong / LI, Rong-Sheng / WANG, Yong-Li / WANG, Chao-Ran / LIANG, Xin-Miao / ZHANG, Wei-Dong / YANG, Ling / LIU, Ping / GE, Guang-Bo

Chinese journal of natural medicines. 2021 Apr., v. 19, no. 4

2021

Abstract: Qing-Fei-Pai-Du decoction (QFPDD) is a Chinese medicine compound formula recommended for combating ...

Abstract	Qing-Fei-Pai-Du decoction (QFPDD) is a Chinese medicine compound formula recommended for combating corona virus disease 2019 (COVID-19) by National Health Commission of the People’s Republic of China. The latest clinical study showed that early treatment with QFPDD was associated with favorable outcomes for patient recovery, viral shedding, hospital stay, and course of the disease. However, the effective constituents of QFPDD remain unclear. In this study, an UHPLC-Q-Orbitrap HRMS based method was developed to identify the chemical constituents in QFPDD and the absorbed prototypes as well as the metabolites in mice serum and tissues following oral administration of QFPDD. A total of 405 chemicals, including 40 kinds of alkaloids, 162 kinds of flavonoids, 44 kinds of organic acids, 71 kinds of triterpene saponins and 88 kinds of other compounds in the water extract of QFPDD were tentatively identified via comparison with the retention times and MS/MS spectra of the standards or refereed by literature. With the help of the standards and in vitro metabolites, 195 chemical components (including 104 prototypes and 91 metabolites) were identified in mice serum after oral administration of QFPDD. In addition, 165, 177, 112, 120, 44, 53 constituents were identified in the lung, liver, heart, kidney, brain, and spleen of QFPDD-treated mice, respectively. These findings provided key information and guidance for further investigation on the pharmacologically active substances and clinical applications of QFPDD.
Keywords	COVID-19 infection ; Oriental traditional medicine ; blood serum ; brain ; flavonoids ; heart ; hospitals ; kidneys ; liver ; lungs ; medicinal properties ; metabolites ; oral administration ; patients ; spleen ; triterpenoid saponins
Language	English
Dates of publication	2021-04
Size	p. 305-320.
Publishing place	Elsevier B.V.
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(21)60031-6
Database	NAL-Catalogue (AGRICOLA)

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Book ; Online ; E-Book: Covid-19 from traditional Chinese medicine perspective

Huang, Luqi / Li, Hao / Qi, Wensheng / Yang, Zhixu / Miao, Qing

severe clinical cases in the context of syndrome differentiation

2021

Author's details	Luqi Huang, Hao Li, Wensheng Qi, Zhixu Yang, Qing Miao
Keywords	Electronic books
Language	English
Size	1 Online-Ressource (xxiv, 351 Seiten), Illustrationen, Diagramme
Publisher	World Scientific
Publishing place	Singapore
Publishing country	Singapore
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT020865342
ISBN	978-981-122-875-9 ; 978-981-122-876-6 ; 9789811228742 ; 981-122-875-2 ; 981-122-876-0 ; 9811228744
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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