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  1. Article ; Online: A pathway towards high-quality development of the manufacturing industry: Does scientific and technological talent matter?

    Li, Dan / Yao, Qiuyu

    PloS one

    2024  Volume 19, Issue 3, Page(s) e0294873

    Abstract: Against the background of the accelerated evolution of the new round of scientific and technological revolution and industrial change, scientific and technical talents, as essential innovation resources, play an important role in promoting the high- ... ...

    Abstract Against the background of the accelerated evolution of the new round of scientific and technological revolution and industrial change, scientific and technical talents, as essential innovation resources, play an important role in promoting the high-quality development of the manufacturing industry. Based on the panel data of 30 provinces in China from 2012 to 2021, the article constructs a fixed-effects model and systematically researches the impact of scientific and technological talents on the high-quality development of the manufacturing industry. The results show that scientific and technical talents play a significant role in promoting the high-quality development of the manufacturing industry, and the upgrading of the consumption structure and the accumulation of productive service industries play a mediating role. Heterogeneity analysis found that the promotion effect of scientific and technical talents is more favorable in the eastern region, medium-technology level manufacturing, and labor-intensive manufacturing. Among the three sub-dimensions of scientific and technological talents, the scale of scientific and technical talents has the most significant impact on the development of the manufacturing industry. The analysis of the spatial spillover effect finds that scientific and technological talents will have a positive spillover effect on the development of the manufacturing industry in neighboring areas. The study provides a basis for relevant departments to formulate effective strategies and policies.
    MeSH term(s) Manufacturing Industry ; Technology ; Industry ; Commerce ; China ; Economic Development
    Language English
    Publishing date 2024-03-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0294873
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Suggestions on home quarantine and recovery of novel coronavirus patients.

    Li, Qiuyu / Liu, Chengyang / Li, Haiyun

    Journal of translational internal medicine

    2023  Volume 11, Issue 2, Page(s) 111–114

    Language English
    Publishing date 2023-07-05
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 2861892-0
    ISSN 2224-4018 ; 2450-131X
    ISSN (online) 2224-4018
    ISSN 2450-131X
    DOI 10.2478/jtim-2023-0085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Multi-scale adversarial learning with difficult region supervision learning models for primary tumor segmentation.

    Zheng, Shenhai / Sun, Qiuyu / Ye, Xin / Li, Weisheng / Yu, Lei / Yang, Chaohui

    Physics in medicine and biology

    2024  Volume 69, Issue 8

    Abstract: Objective. ...

    Abstract Objective.
    MeSH term(s) Cues ; Brain ; Benchmarking ; Databases, Factual ; Pancreas ; Image Processing, Computer-Assisted
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 208857-5
    ISSN 1361-6560 ; 0031-9155
    ISSN (online) 1361-6560
    ISSN 0031-9155
    DOI 10.1088/1361-6560/ad3321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 199: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Stability mechanism of Monascus pigment-soy protein isolate-maltodextrin complex.

    Wang, Qiuyu / Li, Xiaoyu / Hao, Jia / Xu, Duoxia

    Journal of the science of food and agriculture

    2024  

    Abstract: Background: Monascus pigment (MP) is a natural food coloring with vital physiological functions but prone to degradation and color fading under light conditions.: Results: This study investigated the effect of complex formation of soybean protein ... ...

    Abstract Background: Monascus pigment (MP) is a natural food coloring with vital physiological functions but prone to degradation and color fading under light conditions.
    Results: This study investigated the effect of complex formation of soybean protein isolate (SPI), maltodextrin (MD), and MP on the photostability of MP. Light stability was assessed through retention rate and color difference. Fluorescence spectroscopy (FS), circular dichroism (CD), Fourier-transform infrared (FTIR) spectroscopy, and X-ray diffraction (XRD) explored MP, SPI, and MD interactions, clarifying the MP-SPI-MD complex mechanism on the light stability of MP. Microstructure and differential scanning calorimetry (DSC) analyzed the morphology and thermal properties. The retention rate of MP increased to approximately 80%, and minimal color difference was observed when adding SPI and MD simultaneously. FS revealed hydrophobic interaction between MP and SPI. FTIR analysis showed intensity changes and peak shifts in amide I band and amide II band, which proved the hydrophobic interaction. CD showed a decrease in α-helix content and an increase in β-sheet content after complex formation, indicating strengthened hydrogen bonding interactions. Scanning electron microscopy (SEM) analysis demonstrated that MP was attached to the surface and interior of complexes. XRD showed MP as crystalline, while SPI and MD were amorphous, complexes exhibited weakened or absent peaks, suggesting MP encapsulation. The results of DSC were consistent with XRD.
    Conclusion: SPI and MD enveloped MP through hydrogen bonding and hydrophobic interaction, ultimately enhancing its light stability and providing insights for pigment-protein-polysaccharide interactions and improving pigment stability in the food industry. © 2024 Society of Chemical Industry.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.13539
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 808: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Hereditary hemochromatosis caused by a C282Y/H63D mutation in the HFE gene: A case report.

    Li, Dongdong / Li, Jinfeng / Zhang, Hongkun / Zhu, Qiuyu / Wang, Teng / Zhao, Wen / Zhao, Shousong / Li, Wei

    Heliyon

    2024  Volume 10, Issue 7, Page(s) e28046

    Abstract: Hereditary hemochromatosis (HH) is a disease characterized by disordered iron metabolism. It often involves mutations of ... ...

    Abstract Hereditary hemochromatosis (HH) is a disease characterized by disordered iron metabolism. It often involves mutations of the
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e28046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Characterization and Analysis of Corrosion Resistance of Rubber Materials for Downhole Tools in a High-Stress Environment with Coupled H

    Gong, Leilei / Chen, Yulin / Cai, Meng / Li, Junliang / Lu, Qiuyu / Hou, Duo

    Materials (Basel, Switzerland)

    2024  Volume 17, Issue 4

    Abstract: In the process of constructing deep natural gas wells in Sichuan and Chongqing, gas wells encounter various technical challenges such as high temperature, high pressure, and a corrosive environment containing ... ...

    Abstract In the process of constructing deep natural gas wells in Sichuan and Chongqing, gas wells encounter various technical challenges such as high temperature, high pressure, and a corrosive environment containing H
    Language English
    Publishing date 2024-02-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma17040863
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  7. Article ; Online: Study on the Structure and Bioactivity of

    Liu, Yijun / Mai, Biyi / Li, Zhiyun / Feng, Xingqin / Chen, Yunlan / Lin, Lijing / Xia, Qiuyu

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 5

    Abstract: Various carbon sources affect the growth of ... ...

    Abstract Various carbon sources affect the growth of the
    Language English
    Publishing date 2023-04-26
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9050514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Comprehensive characterization of Epimedium-Rhizoma drynariae herb pair in rat plasma, urine, and feces metabolic profiles by UHPLC-Q-Orbitrap HRMS combined with diagnostic extraction strategy and multicomponent pharmacokinetic study by UHPLC-MS/MS.

    Li, Qiuyu / Ren, Mengxin / Liu, Yanzhu / Qin, Feng / Xiong, Zhili

    Analytical and bioanalytical chemistry

    2024  

    Abstract: Epimedium-Rhizoma drynariae (EP-RD) was a well-known herb commonly used to treat bone diseases in traditional Chinese medicine. Nevertheless, there was incomplete pharmacokinetic behavior, metabolic conversion and chemical characterization of EP-RD in ... ...

    Abstract Epimedium-Rhizoma drynariae (EP-RD) was a well-known herb commonly used to treat bone diseases in traditional Chinese medicine. Nevertheless, there was incomplete pharmacokinetic behavior, metabolic conversion and chemical characterization of EP-RD in vivo. Therefore, this study aimed to establish metabolic profiles combined with multicomponent pharmacokinetics to reveal the in vivo behavior of EP-RD. Firstly, the diagnostic product ions (DPIs) and neutral losses (NLs) filtering strategy combined with UHPLC-Q-Orbitrap HRMS for the in vitro chemical composition of EP-RD and metabolic profiles of plasma, urine, and feces after oral administration of EP-RD to rats were proposed to comprehensively characterize the 47 chemical compounds and the 97 exogenous in vivo (35 prototypes and 62 metabolites), and possible biotransformation pathways of EP-RD were proposed, which included phase I reactions such as hydrolysis, hydrogenation, dehydrogenation, hydroxylation, dehydroxylation, isomerization, and demethylation and phase II reactions such as glucuronidation, acetylation, methylation, and sulfation. Moreover, a UHPLC-MS/MS quantitative approach was established for the pharmacokinetic analysis of seven active components: magnoflorine, epimedin A, epimedin B, epimedin C, icariin, baohuoside II, and icariin II. Results indicated that the established method was reliably used for the quantitative study of plasma active ingredients after oral administration of EP-RD in rats. Compared to oral EP alone, the increase in area under curves and maximum plasma drug concentration (P < 0.05). This study increased the understanding of the material basis and biotransformation profiles of EP-RD in vivo, which was of great significance in exploring the pharmacological effects of EP-RD.
    Language English
    Publishing date 2024-04-23
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 201093-8
    ISSN 1618-2650 ; 0016-1152 ; 0372-7920
    ISSN (online) 1618-2650
    ISSN 0016-1152 ; 0372-7920
    DOI 10.1007/s00216-024-05292-y
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    In stock of ZB MED Bonn / Germany

    Z 4' 69/97: Show issues
    Archiv 3: Show issues
    Z 9.4: Show issues

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  9. Article ; Online: Interactions of rhizosphere microbiota-environmental factors-pharmacological active ingredients of Eucommia ulmoides.

    Dong, Chunbo / Shao, Qiuyu / Ran, Qingsong / Li, Xu / Han, Yanfeng

    Planta

    2024  Volume 259, Issue 3, Page(s) 59

    Abstract: Main conclusion: The composition, diversity and co-occurrence patterns of the rhizosphere microbiota of E. ulmoides were significantly influenced by environmental factors, and which were potentially associated with the contents of pharmacological active ...

    Abstract Main conclusion: The composition, diversity and co-occurrence patterns of the rhizosphere microbiota of E. ulmoides were significantly influenced by environmental factors, and which were potentially associated with the contents of pharmacological active ingredients. Eucommia ulmoides is an important perennial medicinal plant. However, little is known about the interactions among microbiota, environmental factors (EFs), and pharmacological active ingredients (PAIs) of E. ulmoides. Herein, we analyzed the interactions among rhizosphere microbiota-EFs-PAIs of E. ulmoides by amplicon sequencing and multi-analytical approach. Our results revealed variations in the dominant genera, diversity, and co-occurrence networks of the rhizosphere microbiota of E. ulmoides across different geographical locations. Notably, available nitrogen exerted the strongest influence on fungal dominant genera, while pH significantly impacted bacterial dominant genera. Rainfall and relative humidity exhibited pronounced effects on the α-diversity of fungal groups, whereas available phosphorus influenced the number of nodes in fungal co-occurrence networks. Altitude and total phosphorus had substantial effects on the average degree and nodes in bacterial co-occurrence networks. Furthermore, the dominant genera, diversity and co-occurrence network of rhizosphere microbiota of E. ulmoides were significantly correlated with the content of PAIs. Specifically, the abundance of rhizosphere dominant genera Filobasidium, Hannaella and Nitrospira were significantly correlated with the content of pinoresinol diglucoside (PD). Similarly, the abundance of Vishniacozyma and Bradyrhizobium correlated significantly with the content of geniposidic acid (GC), while the abundance of Gemmatimonas was significantly correlated with the content of aucubin. Moreover, the bacterial co-occurrence network parameters including average degree, density, and edge, were significantly correlated with the content of GC and aucubin. The α-diversity index Chao1 also displayed a significant correlation with the content of PD. These findings contribute to a more comprehensive understanding of the interactions between medicinal plants and microbes.
    MeSH term(s) Rhizosphere ; Eucommiaceae/chemistry ; Bacteria/genetics ; Plants, Medicinal ; Microbiota ; Phosphorus ; Soil Microbiology ; Soil ; Lignans ; Iridoid Glucosides
    Chemical Substances aucubin (2G52GS8UML) ; geniposidic acid (27741-01-1) ; pinoresinol diglucoside (63902-38-5) ; Phosphorus (27YLU75U4W) ; Soil ; Lignans ; Iridoid Glucosides
    Language English
    Publishing date 2024-02-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 208909-9
    ISSN 1432-2048 ; 0032-0935 ; 1866-2749
    ISSN (online) 1432-2048
    ISSN 0032-0935 ; 1866-2749
    DOI 10.1007/s00425-024-04338-w
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    In stock of ZB MED Bonn / Germany

    Z 46/303: Show issues

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  10. Article: Chinese Baijiu and Whisky: Research Reservoirs for Flavor and Functional Food.

    Li, Jinchen / Zhang, Qiuyu / Sun, Baoguo

    Foods (Basel, Switzerland)

    2023  Volume 12, Issue 15

    Abstract: Baijiu is a traditional spirit with high reputation in the Chinese community, and whisky, on the other hand, is a renowned spirit in Western culture, with both contributing a major proportion to the consumption and revenue in the global spirit market. ... ...

    Abstract Baijiu is a traditional spirit with high reputation in the Chinese community, and whisky, on the other hand, is a renowned spirit in Western culture, with both contributing a major proportion to the consumption and revenue in the global spirit market. Interestingly, starting with similar raw materials, such as grains, diverse production methods lead to different organoleptic profiles. In addition, such enormous attention they attract renders them as a crucial part in food and the related industry. Therefore, great efforts are made in improving product quality and optimizing production processes, such as flavor enhancement, facility development, and deep utilization of byproducts. Given the huge impacts and great involvements of these spirits in the general food industry, research focusing on either spirit is of referential significance for other relevant fields. With the aim of facilitating such collaboration, this review discusses the current research status, in a comparative manner, of both spirits in respect to key production processes-oriented sensory and flavor analysis, deep utilization of byproducts, and spirit-derived functional food investigations. Finally, the internal correlations based on the abovementioned criteria are identified, with research prospects proposed.
    Language English
    Publishing date 2023-07-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2704223-6
    ISSN 2304-8158
    ISSN 2304-8158
    DOI 10.3390/foods12152841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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