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  1. Article ; Online: Thrombopoietin Agonism to Promote Platelet Engraftment Following Hematopoietic Stem Cell Transplantation: Promising, but Not Ready for Primetime.

    Al-Samkari, Hanny

    Transplantation and cellular therapy

    2024  Volume 30, Issue 5, Page(s) 465–467

    MeSH term(s) Hematopoietic Stem Cell Transplantation ; Humans ; Thrombopoietin/therapeutic use ; Thrombopoietin/pharmacology ; Blood Platelets/drug effects ; Blood Platelets/metabolism ; Receptors, Thrombopoietin/agonists ; Animals
    Chemical Substances Thrombopoietin (9014-42-0) ; Receptors, Thrombopoietin
    Language English
    Publishing date 2024-02-13
    Publishing country United States
    Document type Editorial ; Journal Article
    ZDB-ID 3062231-1
    ISSN 2666-6367
    ISSN (online) 2666-6367
    DOI 10.1016/j.jtct.2024.04.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5082: Show issues Location:
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  2. Article ; Online: Even effective drugs require adequately powered trials: Systemic bevacizumab in hereditary hemorrhagic telangiectasia.

    Al-Samkari, Hanny

    Journal of internal medicine

    2023  Volume 294, Issue 6, Page(s) 684–686

    Language English
    Publishing date 2023-08-22
    Publishing country England
    Document type Editorial
    ZDB-ID 96274-0
    ISSN 1365-2796 ; 0954-6820
    ISSN (online) 1365-2796
    ISSN 0954-6820
    DOI 10.1111/joim.13713
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  3. Article ; Online: COVID-19 vaccination and immune thrombocytopenia: Cause for vigilance, but not panic.

    Al-Samkari, Hanny

    Research and practice in thrombosis and haemostasis

    2023  Volume 7, Issue 1, Page(s) 100039

    Language English
    Publishing date 2023-02-15
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1016/j.rpth.2023.100039
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  4. Article ; Online: Treatment of chemotherapy-induced thrombocytopenia with monotherapy versus combination therapy: the devil is in the details.

    Al-Samkari, Hanny

    Research and practice in thrombosis and haemostasis

    2023  Volume 7, Issue 8, Page(s) 102250

    Language English
    Publishing date 2023-11-04
    Publishing country United States
    Document type Journal Article
    ISSN 2475-0379
    ISSN (online) 2475-0379
    DOI 10.1016/j.rpth.2023.102250
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  5. Article ; Online: Optimal management of chemotherapy-induced thrombocytopenia with thrombopoietin receptor agonists.

    Al-Samkari, Hanny

    Blood reviews

    2023  Volume 63, Page(s) 101139

    Abstract: Chemotherapy-induced thrombocytopenia (CIT) is a common complication of antineoplastic therapy, resulting in antineoplastic therapy dose reductions, treatment delays, treatment discontinuation, and morbid bleeding events. Despite several decades of ... ...

    Abstract Chemotherapy-induced thrombocytopenia (CIT) is a common complication of antineoplastic therapy, resulting in antineoplastic therapy dose reductions, treatment delays, treatment discontinuation, and morbid bleeding events. Despite several decades of research into thrombopoietic growth factors in CIT, there are presently no available U.S. FDA- or EMA-approved agents to treat CIT. However, a respectable body of evidence has been published evaluating the thrombopoietin receptor agonists (TPO-RAs) for the management and prevention of CIT in patients with solid tumors, and critical studies are ongoing with the TPO-RAs romiplostim and avatrombopag. When employed in the appropriate patient population and used properly, TPO-RAs can successfully and safely manage CIT for extended periods of time with minimal apparent risks. This comprehensive review discusses the evidence for TPO-RAs in CIT in patients with solid tumors, provides detailed guidance for their use in the clinic, and discusses ongoing essential clinical trials in management of CIT.
    MeSH term(s) Humans ; Thrombocytopenia/chemically induced ; Thrombocytopenia/drug therapy ; Receptors, Thrombopoietin/agonists ; Antineoplastic Agents/adverse effects ; Neoplasms/complications ; Neoplasms/drug therapy ; Risk
    Chemical Substances Receptors, Thrombopoietin ; Antineoplastic Agents
    Language English
    Publishing date 2023-10-18
    Publishing country England
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 639015-8
    ISSN 1532-1681 ; 0268-960X
    ISSN (online) 1532-1681
    ISSN 0268-960X
    DOI 10.1016/j.blre.2023.101139
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    Zs.A 2207: Show issues Location:
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  6. Article ; Online: Adenovirus-associated thrombosis and thrombocytopenia: an emerging anti-PF4 disorder.

    Song, Andrew B / Al-Samkari, Hanny

    Haematologica

    2024  

    Abstract: Not available. ...

    Abstract Not available.
    Language English
    Publishing date 2024-02-08
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.284460
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  7. Article ; Online: Doxycycline for bleeding in hereditary hemorrhagic telangiectasia: When low-hanging fruit meets inconvenient data.

    Al-Samkari, Hanny

    Journal of thrombosis and haemostasis : JTH

    2022  Volume 20, Issue 5, Page(s) 1067–1069

    MeSH term(s) Doxycycline ; Epistaxis ; Humans ; Telangiectasia, Hereditary Hemorrhagic/complications ; Telangiectasia, Hereditary Hemorrhagic/diagnosis ; Telangiectasia, Hereditary Hemorrhagic/drug therapy
    Chemical Substances Doxycycline (N12000U13O)
    Language English
    Publishing date 2022-05-02
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 2112661-6
    ISSN 1538-7836 ; 1538-7933
    ISSN (online) 1538-7836
    ISSN 1538-7933
    DOI 10.1111/jth.15675
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    Zs.A 5805: Show issues Location:
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    Zs.MO 295: Show issues

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  8. Article ; Online: Platelet clump visible to the naked eye in type 2B von Willebrand disease.

    Al-Samkari, Hanny

    Blood

    2022  Volume 138, Issue 25, Page(s) 2742

    MeSH term(s) Adult ; Blood Platelet Disorders/complications ; Blood Platelet Disorders/pathology ; Blood Platelets/pathology ; Female ; Humans ; Platelet Aggregation ; Platelet Count ; von Willebrand Disease, Type 2/complications ; von Willebrand Disease, Type 2/pathology
    Language English
    Publishing date 2022-01-20
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2021013652
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  9. Article: Pyruvate kinase deficiency: clinical expression and new therapies.

    Al-Samkari, Hanny

    Clinical advances in hematology & oncology : H&O

    2022  Volume 20, Issue 7, Page(s) 422–425

    MeSH term(s) Anemia, Hemolytic, Congenital Nonspherocytic ; Erythrocytes ; Humans ; Pyruvate Kinase/deficiency ; Pyruvate Kinase/genetics ; Pyruvate Metabolism, Inborn Errors/therapy
    Chemical Substances Pyruvate Kinase (EC 2.7.1.40)
    Language English
    Publishing date 2022-07-08
    Publishing country United States
    Document type Interview
    ZDB-ID 2271951-9
    ISSN 1543-0790
    ISSN 1543-0790
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6505: Show issues Location:
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  10. Article ; Online: Splanchnic vein thrombosis in the patient with cirrhosis: Better anticoagulated than not (for most patients).

    Al-Samkari, Hanny

    Thrombosis research

    2022  Volume 218, Page(s) 201–202

    MeSH term(s) Anticoagulants/therapeutic use ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/drug therapy ; Liver Cirrhosis/pathology ; Portal Vein/pathology ; Splanchnic Circulation ; Venous Thrombosis/complications ; Venous Thrombosis/drug therapy
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-07-25
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2022.07.009
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    Zs.A 863: Show issues Location:
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