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  1. Article: Efficacy and safety analysis of TACE + PEI + lenvatinib compared with TACE + lenvatinib for the treatment of hepatocellular carcinoma with PVTT: a retrospective study.

    Lu, Haohao / Zheng, Chuansheng / Liang, Bin / Xia, Xiangwen / Fan, Hongjie

    Frontiers in oncology

    2024  Volume 14, Page(s) 1280837

    Abstract: Objective: The aim of this study was to investigate the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with percutaneous ethanol injection (PEI) and lenvatinib in HCC patients with PVTT (Vp2-3), thus providing a safe and ...

    Abstract Objective: The aim of this study was to investigate the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with percutaneous ethanol injection (PEI) and lenvatinib in HCC patients with PVTT (Vp2-3), thus providing a safe and effective treatment strategy for advanced HCC patients.
    Materials and methods: Clinical data of 227 patients with unresectable HCC and PVTT treated at the Union Hospital from January 2018 to December 2021 were retrospectively analyzed. The patients were divided into two groups according to their treatment methods: TACE+PEI+lenvatinib group (N=103) and TACE+lenvatinib group (N=124).
    Results: The proportion of patients with disappearance, shrinkage, or no change of PVTT after treatment was significantly higher in the TACE+PEI+lenvatinib group compared to the TACE+lenvatinib group, with statistical significance (P<0.001). The TACE+PEI+lenvatinib group had higher objective response rate (ORR) (50.5% vs. 25.8%, P<0.001) and disease control rate (DCR) (87.4% vs. 74.2%, P=0.013) than the TACE+lenvatinib group. The median progression-free survival (mPFS) of the TACE+PEI+lenvatinib group was longer than that of the TACE+lenvatinib group (8.1 months vs. 6.5 months, P<0.001). Consistently, the median overall survival (mOS) of the TACE+PEI+lenvatinib group was longer than that of the TACE+lenvatinib group (17.1 months vs. 13.9 months, P<0.001).
    Conclusion: Among HCC patients with PVTT (Vp2-3), TACE+PEI+lenvatinib is more effective comparing to TACE+lenvatinib in prolonging PFS and OS. The control of PVTT in the TACE+PEI+lenvatinib group was significantly more satisfactory than that in the TACE+lenvatinib group. TACE+PEI+lenvatinib is a safe and effective treatment strategy for HCC patients with PVTT (Vp2-3).
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2024.1280837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of the pre-crosslinking of Ba

    Li, Yan / Wu, Yuzhi / Zhai, Hongjie / Qiao, Cuixia / Zhao, Gang / Xue, Zhixin / Xia, Yanzhi

    International journal of biological macromolecules

    2024  Volume 259, Issue Pt 1, Page(s) 129169

    Abstract: Decreased coagulation bath concentration and difficult recovery are classical issues observed during the wet spinning of fibers. In this paper, a novel method was presented for preparing environment-friendly agar fibers using deionized water as the ... ...

    Abstract Decreased coagulation bath concentration and difficult recovery are classical issues observed during the wet spinning of fibers. In this paper, a novel method was presented for preparing environment-friendly agar fibers using deionized water as the coagulation and stretch baths. The addition of Ba
    MeSH term(s) Agar ; Water/chemistry ; Temperature ; Microscopy, Electron, Scanning
    Chemical Substances Agar (9002-18-0) ; Water (059QF0KO0R)
    Language English
    Publishing date 2024-01-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2023.129169
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2374: Show issues Location:
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  3. Article ; Online: Screening of Transition Metal Supported on Black Phosphorus as Electrocatalysts for CO

    Zhong, Weichan / Yue, Jingxiu / Zhang, Rongxin / Huang, Hongjie / Huang, Hong / Shen, Zhangfeng / Jiang, Lingchang / Xu, Minhong / Xia, Qineng / Cao, Yongyong

    Inorganic chemistry

    2024  Volume 63, Issue 2, Page(s) 1035–1045

    Abstract: The electrocatalytic ... ...

    Abstract The electrocatalytic CO
    Language English
    Publishing date 2024-01-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.3c03320
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  4. Article ; Conference proceedings: Short Lecture "Search for diversified miliusane compounds from Miliusa plants for anticancer drug discovery"

    Zhang, Hongjie / Xie, Wen-Jian / Xia, Yi-Xuan

    Planta Medica

    2023  Volume 89, Issue 14

    Event/congress 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Trinity College Dublin Ireland, 2023-07-02
    Language English
    Publishing date 2023-11-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 123545-x
    ISSN 1439-0221 ; 0032-0943
    ISSN (online) 1439-0221
    ISSN 0032-0943
    DOI 10.1055/s-0043-1773879
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Population Structure, Genetic Diversity, and Conservation Strategies of a Commercially Important Sleeper Fish,

    Hu, Yun / Li, Hongjie / Xia, Jianhong / Li, Chenhong

    Frontiers in genetics

    2022  Volume 13, Page(s) 843848

    Abstract: Odontobutis ... ...

    Abstract Odontobutis potamophilus
    Language English
    Publishing date 2022-05-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2022.843848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Construction of self-enhanced luminescence probes based on Ti

    Wei, Zhihao / Zhang, Huixin / Zhang, Feifei / Xia, Jianfei / Meng, Qingyang / Huang, Hongjie / Wang, Zonghua

    Biosensors & bioelectronics

    2024  Volume 256, Page(s) 116236

    Abstract: Au nano-clusters (Au NCs) were promising electrochemiluminescence (ECL) nano-materials. However, the small size of Au NCs presented a challenge in terms of their immobilization during the construction of an ECL biosensing platform. This limitation ... ...

    Abstract Au nano-clusters (Au NCs) were promising electrochemiluminescence (ECL) nano-materials. However, the small size of Au NCs presented a challenge in terms of their immobilization during the construction of an ECL biosensing platform. This limitation significantly hindered the wider application of Au NCs in the ECL field. In this work, we successfully used the reducibility of Ti
    MeSH term(s) Titanium/chemistry ; Biosensing Techniques/methods ; Humans ; Luminescent Measurements/methods ; Gold/chemistry ; Limit of Detection ; Polynucleotide 5'-Hydroxyl-Kinase/analysis ; Electrochemical Techniques/methods ; Metal Nanoparticles/chemistry ; Luminescent Agents/chemistry
    Chemical Substances Titanium (D1JT611TNE) ; Gold (7440-57-5) ; titanium dioxide (15FIX9V2JP) ; Polynucleotide 5'-Hydroxyl-Kinase (EC 2.7.1.78) ; titanium carbide (12070-08-5) ; Luminescent Agents
    Language English
    Publishing date 2024-04-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1011023-9
    ISSN 1873-4235 ; 0956-5663
    ISSN (online) 1873-4235
    ISSN 0956-5663
    DOI 10.1016/j.bios.2024.116236
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2275: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  7. Article ; Online: Application of 3D printing technology for green synthesis of Fe

    Liu, Dingyong / Cai, Hongjie / Zhou, Weiming / Lei, Dandan / Cao, Changlin / Xia, Xinshu / Xiao, Liren / Qian, Qingrong / Chen, Qinghua

    RSC advances

    2024  Volume 14, Issue 2, Page(s) 1501–1512

    Abstract: Photocatalysis is widely acknowledged as an efficient and environmentally friendly method for treating dye-contaminated wastewater. However, the utilization of powdered photocatalysts presents significant challenges, including issues related to ... ...

    Abstract Photocatalysis is widely acknowledged as an efficient and environmentally friendly method for treating dye-contaminated wastewater. However, the utilization of powdered photocatalysts presents significant challenges, including issues related to recyclability and the potential for secondary pollution. Herein, a novel technique based on 3D printing for the synthesizing of iron oxide (Fe
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ISSN 2046-2069
    ISSN (online) 2046-2069
    DOI 10.1039/d3ra07143j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: An electrochemiluminescence aptasensor based on Ti

    Du, Lin / Zhang, Huixin / Zhang, Feifei / Xia, Jianfei / Meng, Qingyang / Huang, Hongjie / Wang, Zonghua

    Talanta

    2023  Volume 270, Page(s) 125574

    Abstract: Developing a highly selective and sensitive analysis strategy for lincomycin (LIN) is of great significance for environmental protection and food safety. Herein, we reported a novel electrochemiluminescence (ECL) aptasensor based on ... ...

    Abstract Developing a highly selective and sensitive analysis strategy for lincomycin (LIN) is of great significance for environmental protection and food safety. Herein, we reported a novel electrochemiluminescence (ECL) aptasensor based on Ti
    MeSH term(s) Molybdenum ; Titanium ; Catalysis ; Electric Conductivity ; Lincomycin
    Chemical Substances Molybdenum (81AH48963U) ; Titanium (D1JT611TNE) ; Lincomycin (BOD072YW0F)
    Language English
    Publishing date 2023-12-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.125574
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  9. Article ; Online: Ultrasound-assisted enzymatic hydrolysis of yeast β-glucan catalyzed by β-glucanase

    Hongjie Yuan / Yan He / Hua Zhang / Xia Ma

    Ultrasonics Sonochemistry, Vol 86, Iss , Pp 106012- (2022)

    Chemical and microstructural analysis

    2022  

    Abstract: The purpose of this study was to investigate the effect of ultrasound-assisted enzymolysis on modified solubilization of yeast β-glucan and its related mechanism. The depolymerization effects of this system on the physicochemical properties and ... ...

    Abstract The purpose of this study was to investigate the effect of ultrasound-assisted enzymolysis on modified solubilization of yeast β-glucan and its related mechanism. The depolymerization effects of this system on the physicochemical properties and structural features of the degraded fragments were studied systematically. The structure and physicochemical properties of the samples showed that the solubility of yeast β-glucan achieved 75.35 % after modification; and ultrasonic enzymatic enhanced the degradation efficiency. The yeast β-glucan obtained after solubilization and modification owned better antioxidant activities. The yeast β-glucan particles become obviously smaller, sparsely dispersed in the aqueous solution and the stability was improved. In addition, the hydrogen bonds in yeast β-glucan native triple helix structure were partially broken. Moreover, the disruption of yeast β-glucan's original structure made it decreased thermostability and easier to dissolve in water. The atomic force microscope (AFM) imaging directly verified the branched-chain morphology of yeast β-glucan and the small-strand degradation fragments. Therefore, this research can provide a feasible and effective approach for improving solubility of water-insoluble yeast β-glucan to enlarge its food and biomedical applications.
    Keywords Yeast β-glucan ; Ultrasound ; Enzymolysis ; Modification ; Structural features ; Depolymerization ; Chemistry ; QD1-999 ; Acoustics. Sound ; QC221-246
    Subject code 540
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Pathogenic mechanisms of osteogenesis imperfecta, evidence for classification.

    Yu, Hongjie / Li, Changrong / Wu, Huixiao / Xia, Weibo / Wang, Yanzhou / Zhao, Jiajun / Xu, Chao

    Orphanet journal of rare diseases

    2023  Volume 18, Issue 1, Page(s) 234

    Abstract: Osteogenesis imperfecta (OI) is a connective tissue disorder affecting the skeleton and other organs, which has multiple genetic patterns, numerous causative genes, and complex pathogenic mechanisms. The previous classifications lack structure and ... ...

    Abstract Osteogenesis imperfecta (OI) is a connective tissue disorder affecting the skeleton and other organs, which has multiple genetic patterns, numerous causative genes, and complex pathogenic mechanisms. The previous classifications lack structure and scientific basis and have poor applicability. In this paper, we summarize and sort out the pathogenic mechanisms of OI, and analyze the molecular pathogenic mechanisms of OI from the perspectives of type I collagen defects(synthesis defects, processing defects, post-translational modification defects, folding and cross-linking defects), bone mineralization disorders, osteoblast differentiation and functional defects respectively, and also generalize several new untyped OI-causing genes and their pathogenic mechanisms, intending to provide the evidence of classification and a scientific basis for the precise diagnosis and treatment of OI.
    MeSH term(s) Humans ; Osteogenesis Imperfecta/genetics ; Collagen Type I/genetics ; Osteogenesis/genetics ; Calcification, Physiologic ; Bone Diseases ; Mutation
    Chemical Substances Collagen Type I
    Language English
    Publishing date 2023-08-09
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2225857-7
    ISSN 1750-1172 ; 1750-1172
    ISSN (online) 1750-1172
    ISSN 1750-1172
    DOI 10.1186/s13023-023-02849-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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