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Article ; Online: The Influence of Higher Education on Student Learning and Agency for Sustainability Transition

Elizabeth Sidiropoulos

Sustainability, Vol 14, Iss 3098, p

2022 Volume 3098

Abstract: Higher education (HE) has a key role in educating graduates as decision makers and change agents; however, sustainability education (SE) remains on the fringes of mainstream curricula and is conducted on an ad hoc basis. The context of this research is ... ...

Abstract	Higher education (HE) has a key role in educating graduates as decision makers and change agents; however, sustainability education (SE) remains on the fringes of mainstream curricula and is conducted on an ad hoc basis. The context of this research is five connected studies that aimed to investigate the influence of SE on tertiary students’ views, knowledge, behaviour, and agency to contribute to sustainability transitions. The mixed-methods study investigated learning for sustainability by focusing on key elements of the “learning system”, namely the learner’s personal context, the teaching context (SE compared to regular education) and learning outcomes. The research was guided by a unique conceptual framework that linked theories in education and learning, environmental psychology, and sustainability transitions. The influence of educational interventions was assessed using online pre-post surveys that consisted of well-established instruments and open-ended questions. Key transversal findings are resistance to SE, converging views and attitudes towards an “anthropocentric environmentalist” perspective, limited empowerment and occasional disempowerment from SE, a focus on personal behaviour change rather than professional action/agency, and a limited incidence of wider agency. Cumulative and deeper learning for sustainability occurred with repetition of SE and a greater connection to a student’s lifeworld. The current ad hoc approach to SE in HE is ineffective in creating widespread agents for change. Influences that foster transformative learning for sustainability and the development of competency and agency for sustainability are identified, and recommendations are provided for educational policy and praxis to enhance student learning and agency for sustainability transitions.
Keywords	sustainability education ; ESD ; transformative learning ; LAS ; NEP ; tertiary students ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
Subject code	370
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Existence of solutions to indefinite quasilinear elliptic problems of p-q-Laplacian type

Nikolaos E. Sidiropoulos

Electronic Journal of Differential Equations, Vol 2010, Iss 162,, Pp 1-

2010 Volume 23

Abstract: We study the indefinite quasilinear elliptic problem $$displaylines{ -Delta u-Delta _{p}u=a(x)|u|^ ...

Abstract	We study the indefinite quasilinear elliptic problem $$displaylines{ -Delta u-Delta _{p}u=a(x)\|u\|^{q-2}u-b(x)\|u\|^{s-2}u quadhbox{in }Omega , cr u=0quadhbox{on }partial Omega , }$$ where $Omega $ is a bounded domain in $mathbb{R}^{N}$, $Ngeq 2$, with a sufficiently smooth boundary, $q,s$ are subcritical exponents, $a(cdot)$ changes sign and $b(x)geq 0$ a.e. in $Omega$. Our proofs are variational in character and are based either on the fibering method or the mountain pass theorem.
Keywords	Indefinite quasilinear elliptic problems ; subcritical nonlinearities ; p-Laplacian ; p-q-Laplacian ; fibering method ; mountain pass theorem ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Mathematics ; DOAJ:Mathematics and Statistics
Language	English
Publishing date	2010-11-01T00:00:00Z
Publisher	Texas State University
Document type	Article ; Online
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Article ; Online: Comment on Oldrini et al. PHILOS Synthesis for Proximal Humerus Fractures Has High Complications and Reintervention Rates

Konstantinos Sidiropoulos / Konstantinos Tsikopoulos

Life, Vol 12, Iss 8, p

A Systematic Review and Meta-Analysis. Life 2022, 12 , 311

2022 Volume 1281

Abstract: We read the paper published by Oldrini, L.M. et al. (2022) [.] ...

Abstract	We read the paper published by Oldrini, L.M. et al. (2022) [.]
Keywords	n/a ; Science ; Q
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: A New Approach to the Optimization of Looped Water Distribution Networks with Velocity Constraints

Antonis Manolis / Epaminondas Sidiropoulos

Hydrology, Vol 9, Iss 73, p

2022 Volume 73

Abstract: The optimal design of a looped water distribution system is a problem that is addressed frequently in the literature. Usually, the flow velocity in the pipes is not taken into account. Nevertheless, in real-life applications, there are velocity ... ...

Abstract	The optimal design of a looped water distribution system is a problem that is addressed frequently in the literature. Usually, the flow velocity in the pipes is not taken into account. Nevertheless, in real-life applications, there are velocity restrictions that must be considered for the proper function of water distribution systems. An algorithm has been presented recently for the optimal design of such systems, relying entirely on the hydraulic characteristics of the system, and not involving any parameters to be adjusted. This paper presents a new suitably designed algorithm that retained the features of the original algorithm and handled the problem of velocity restrictions without recourse to penalty functions. The new algorithm was tested and compared with others that used penalty functions to handle the velocity constraints. The results demonstrated its efficiency, reliability, and better performance.
Keywords	optimization ; water distribution networks ; least-cost design ; velocity constraints ; Science ; Q
Subject code	006
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
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Article ; Online: Cost of Illness, Quality of Life, and Work Productivity in Axial Spondyloarthritis Patients Receiving Biological Treatments in Greece.

Kougkas, Nikolaos / Mylonas, Charalambos / Avgoustidis, Nestor / Flouri, Irini / Sidiropoulos, Prodromos / Dimitroulas, Theodoros / Garyfallos, Alexandros

Mediterranean journal of rheumatology

2023 Volume 34, Issue 1, Page(s) 37–43

Abstract: Objectives: To estimate the cost of illness, quality of life and work productivity in patients with Axial Spondyloarthritis (Axial SpA) under biological treatment in Greece.: Methods: We conducted a prospective study of 12-month duration, of patients ...

Abstract	Objectives: To estimate the cost of illness, quality of life and work productivity in patients with Axial Spondyloarthritis (Axial SpA) under biological treatment in Greece. Methods: We conducted a prospective study of 12-month duration, of patients with Axial SpA from a tertiary hospital in Greece. Adult patients fulfilling the Assessment of SpondyloArthritis international Society (ASAS) criteria were enrolled at the beginning of biological treatment due to active disease [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) >4] and failure of first line treatment. All participants completed questionnaires about quality of life, financial costs and work productivity at the same time with the disease activity assessment. Results: 74 patients of whom 57 (77%) with a paid job, were included in the study. The total annual cost for Axial SpA patients is € 9,012.40 while the average cost of acquisition and administration of the drugs is € 8,364. The mean BASDAI in the 52 weeks of follow-up, was decreased from 5.74 to 3.2 and the mean Health Assessment Questionnaire (HAQ) also from 1.13 to 0.75. Work productivity of these patients as measured with the Work Productivity and Activity Impairment Questionnaire (WPAI), was significantly impaired at the baseline and improved after the initiation of biological treatment. Conclusions: The cost of illness in patients receiving biological treatments in Greece is high. However, these treatments except from the well-established positive effect on disease activity, can improve remarkably the work productivity and quality of life of Axial SpA patients.
Language	English
Publishing date	2023-03-31
Publishing country	Greece
Document type	Journal Article
ZDB-ID	3019943-8
ISSN	2529-198X ; 2459-3516
ISSN (online)	2529-198X
ISSN	2459-3516
DOI	10.31138/mjr.34.1.37
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Article ; Conference proceedings: Comparison of endoscopic treatment outcomes between Dieulafoy’s lesion and peptic ulcer: A 10-year single-center retrospective study

Braimakis, I. / Leventaki, F. / Sidiropoulos, O. / Poutakidis, C. / Kouimtsidis, I. / Chachopoulos, C. / Zantza, P. S. / Stasinos, I. / Kalantzis, C. / Tsibouris, P. / Apostolopoulos, P.

Endoscopy

2024 Volume 56, Issue S 02

Event/congress	ESGE Days 2024, Berlin, Germany, 2024-04-25
Language	English
Publishing date	2024-04-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0044-1783305
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Zs.A 669: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Conference proceedings: Impact of periampullary diverticulum on ERCP outcomes, per procedure indication: A 10-year retrospective study

Braimakis, I. / Leventaki, F. / Sidiropoulos, O. / Kouimtsidis, I. / Chachopoulos, C. / Zantza, P. S. / Stasinos, I. / Kalantzis, C. / Tsibouris, P. / Apostolopoulos, P.

Endoscopy

2024 Volume 56, Issue S 02

Event/congress	ESGE Days 2024, Berlin, Germany, 2024-04-25
Language	English
Publishing date	2024-04-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0044-1783130
Database	Thieme publisher's database

In stock of ZB MED Cologne/Königswinter

Zs.A 669: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Patterns of comorbidities differentially affect long-term functional evolution and disease activity in patients with 'difficult to treat' rheumatoid arthritis.

Bertsias, Antonios / Flouri, Irini D / Repa, Argyro / Avgoustidis, Nestor / Kalogiannaki, Eleni / Pitsigavdaki, Sofia / Bertsias, George / Sidiropoulos, Prodromos

RMD open

2024 Volume 10, Issue 1

Abstract: ... p<0.0001 for both) and DAS28 evolution (p<0.0001 and p=0.018, respectively).: Conclusion: D2T ...

Abstract	Background: Characterisation of the long-term outcome of patients with 'difficult to treat' (D2T) rheumatoid arthritis and factors contributing to its evolution are unknown. Herein, we explored the heterogeneity and contributing factors of D2T long-term outcome. Methods: Patients included from a prospective single centre cohort study. The EULAR definition of D2T was applied. Longitudinal clustering of functional status (modified Health Assessment Questionnaire (mHAQ)) and disease activity (Disease Activity Score-28 (DAS28)) were assessed using latent-class trajectory analysis. Multiple linear mixed models were used to examine the impact of comorbidities and their clusters on the long-term outcome. Results: 251 out of 1264 patients (19.9%) were identified as D2T. Younger age, fibromyalgia, osteoarthritis, DAS28-erythrocyte sedimentation rate (ESR) at first biological or targeted synthetic disease-modifying antirheumatic drug (b/ts-DMARD) initiation and failure to reduce DAS28-ESR scores within the first 6 months of b/ts-DMARD therapy were significant predictors of patients becoming D2T. Long-term follow-up (total of 5872 person-years) revealed four groups of functional status evolution: 18.2% had stable, mildly compromised mHAQ (mean 0.41), 39.9% had gradual improvement (1.21-0.87) and two groups had either slow deterioration or stable significant functional impairment (HAQ>1). Similarly, four distinct groups of disease activity evolution were identified. Among the different clusters of comorbidities assessed, presence of 'mental-health and pain-related illnesses' or 'metabolic diseases' had significant contribution to mHAQ worsening (p<0.0001 for both) and DAS28 evolution (p<0.0001 and p=0.018, respectively). Conclusion: D2T patients represent a heterogeneous group in terms of long-term disease course. Mental-health/pain-related illnesses as well as metabolic diseases contribute to long-term adverse outcomes and should be targeted in order to optimise the prognosis of this subset of rheumatoid arthritis.
MeSH term(s)	Humans ; Child, Preschool ; Cohort Studies ; Prospective Studies ; Arthritis, Rheumatoid/diagnosis ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/epidemiology ; Antirheumatic Agents/therapeutic use ; Pain/drug therapy ; Mitoxantrone/analogs & derivatives
Chemical Substances	1-hydroxy-5,8-bis(2-((2-hydroxyethyl)amino)ethylamino)-9,10-anthracenedione (80189-44-2) ; Antirheumatic Agents ; Mitoxantrone (BZ114NVM5P)
Language	English
Publishing date	2024-01-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2812592-7
ISSN	2056-5933 ; 2056-5933
ISSN (online)	2056-5933
ISSN	2056-5933
DOI	10.1136/rmdopen-2023-003808
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Article: Efficacy of esophageal stents as a primary therapeutic option in spontaneous esophageal perforations: a systematic review and meta-analysis of observational studies.

Margaris, Ioannis / Triantafyllou, Tania / Sidiropoulos, Theodoros A / Sideris, Giorgos / Theodorou, Dimitrios / Arkadopoulos, Nikolaos / Michalopoulos, Nikolaos V

Annals of gastroenterology

2024 Volume 37, Issue 2, Page(s) 156–171

Abstract: ... to a statistically significant increase in treatment failure (odds ratio 1.85, 95%CI 0.37-9.30; P=0.72). Drainage ...

Abstract	Background: Spontaneous esophageal perforation traditionally mandates urgent surgical treatment. Lately, esophageal stents have been used to reduce the associated morbidity and mortality. The current systematic review aimed to assess the efficacy of stents as a primary treatment option in this scenario. Methods: A systematic search was conducted in PubMed/MEDLINE, Scopus and the Cochrane Library for studies published in the English language between 2000 and 2023. We included observational studies reporting on the use of stents, alongside conservative measures and drainage procedures, in patients with spontaneous esophageal perforations. Primary outcomes were sealing rate (persistent leak occlusion) and failure rate (mortality or conversion to a major surgical operation). Secondary outcomes included patients' presentation, sepsis, drainage procedures, and reinterventions. Results for primary outcomes were presented as pooled rates with 95% confidence intervals (CIs), using a random-effects model. Methodological quality was assessed using the MINORS score. Results: Eighteen studies involving 171 patients were included. Sealing rate was 86% (95%CI 77-93%) and failure rate was 14% (95%CI 7-22%). Weighted mortality rate was 6% (95%CI 2-13%), while conversion to surgical treatment was 2% (95%CI 0-9%). Late presentation was not related to a statistically significant increase in treatment failure (odds ratio 1.85, 95%CI 0.37-9.30; P=0.72). Drainage procedures were required for the majority of patients, with a high rate of surgical and endoscopic reinterventions. Conclusions: Our results imply that stents may offer an effective and safe alternative treatment for patients with spontaneous esophageal perforations. Additional endoscopic and surgical drainage procedures are frequently needed.
Language	English
Publishing date	2024-02-12
Publishing country	Greece
Document type	Journal Article
ZDB-ID	2032850-3
ISSN	1108-7471
ISSN	1108-7471
DOI	10.20524/aog.2024.0857
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Article ; Online: Therapeutic Applications of Botulinum Neurotoxin for Autonomic Symptoms in Parkinson’s Disease

Steven D. Mitchell / Christos Sidiropoulos

Toxins, Vol 13, Iss 226, p

An Updated Review

2021 Volume 226

Abstract: Parkinson’s disease is the most common age-related motoric neurodegenerative disease. In addition to the cardinal motor symptoms of tremor, rigidity, bradykinesia, and postural instability, there are numerous non-motor symptoms as well. Among the non- ... ...

Abstract	Parkinson’s disease is the most common age-related motoric neurodegenerative disease. In addition to the cardinal motor symptoms of tremor, rigidity, bradykinesia, and postural instability, there are numerous non-motor symptoms as well. Among the non-motor symptoms, autonomic nervous system dysfunction is common. Autonomic symptoms associated with Parkinson’s disease include sialorrhea, hyperhidrosis, gastrointestinal dysfunction, and urinary dysfunction. Botulinum neurotoxin has been shown to potentially improve these autonomic symptoms. In this review, the varied uses of botulinum neurotoxin for autonomic dysfunction in Parkinson’s disease are discussed. This review also includes discussion of some additional indications for the use of botulinum neurotoxin in Parkinson’s disease, including pain.
Keywords	autonomic ; botulinum neurotoxin ; botulinum toxin ; non-motor ; Parkinson’s disease ; Medicine ; R
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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