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  1. Article ; Online: In regard to: "Dosimetric predictive factors for facial nerve paralysis after Cyberknife stereotactic radiotherapy for vestibular schwannomas: A single institution experience of 88 patients".

    Conti, Alfredo

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

    2023  Volume 187, Page(s) 109796

    MeSH term(s) Humans ; Neuroma, Acoustic/radiotherapy ; Neuroma, Acoustic/surgery ; Facial Nerve ; Treatment Outcome ; Dose Fractionation, Radiation ; Radiosurgery/adverse effects ; Paralysis ; Retrospective Studies
    Language English
    Publishing date 2023-07-07
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 605646-5
    ISSN 1879-0887 ; 0167-8140
    ISSN (online) 1879-0887
    ISSN 0167-8140
    DOI 10.1016/j.radonc.2023.109796
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: 50 Years After Schizophrenia and Cyclothymia, Results and Problems

    Conti, Norberto A

    Vertex (Buenos Aires, Argentina)

    2023  Volume 34, Issue 160, abr.-jun., Page(s) 129–137

    Title translation A 50 años de Esquizofrenia y Ciclotimia, resultados y problemas.
    MeSH term(s) Humans ; Schizophrenia ; Cyclothymic Disorder ; Methotrexate ; Cyclophosphamide ; Prednisone ; Retrospective Studies
    Chemical Substances Methotrexate (YL5FZ2Y5U1) ; Cyclophosphamide (8N3DW7272P) ; Prednisone (VB0R961HZT)
    Language Spanish
    Publishing date 2023-07-10
    Publishing country Argentina
    Document type English Abstract ; Journal Article
    ISSN 0327-6139
    ISSN 0327-6139
    DOI 10.53680/vertex.v34i160.466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Editorial: Impact of radiotherapy and radiosurgery on neuro-oncology.

    Conti, Alfredo

    Frontiers in oncology

    2022  Volume 12, Page(s) 978709

    Language English
    Publishing date 2022-07-26
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2022.978709
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Medicine matters in five comedies of Shakespeare

    Camaiora, Luisa / Conti, Andrea A.

    from the Renaissance context to a reading of the plays

    (Natur, Wissenschaft und die Künste ; volume 16)

    2016  

    Author's details Luisa Camaiora & Andrea A. Conti
    Series title Natur, Wissenschaft und die Künste ; volume 16
    Collection
    Keywords Shakespeare, William ; Medizin
    Language English
    Size 244 Seiten
    Publisher Peter Lang
    Publishing place Bern
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019065475
    ISBN 978-3-0343-2192-1 ; 9783034323130 ; 9783035109443 ; 3-0343-2192-9 ; 3034323131 ; 3035109443
    Database Catalogue ZB MED Medicine, Health

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  5. Article ; Online: A Promising Breakthrough: The Potential of VORASIDENIB in the Treatment of Low-grade Glioma.

    Bombino, Alice / Magnani, Marcello / Conti, Alfredo

    Current molecular pharmacology

    2024  

    Abstract: Introduction: Gliomas are common malignant brain tumors characterized by diffuse brain infiltration. World Health Organization grade II and grade III diffuse gliomas are considered lower-grade gliomas (LGGs) and have isocitrate dehydrogenase (IDH) ... ...

    Abstract Introduction: Gliomas are common malignant brain tumors characterized by diffuse brain infiltration. World Health Organization grade II and grade III diffuse gliomas are considered lower-grade gliomas (LGGs) and have isocitrate dehydrogenase (IDH) mutations. LGGs are challenging due to their infiltrative nature, making them capable of progressing into higher-grade malignancies. Vorasidenib is a novel therapeutic agent targeting mutant IDH1/2, sparking interest in the field.
    Mechanism of action: Vorasidenib inhibits mutant IDH1/2 through a unique mechanism, reducing the production of the oncometabolite 2-hydroxyglutarate (2-HG). This alteration affects key enzymes and DNA methylation, impacting tumor growth and invasion. Preclinical Evidence: Preclinical studies show vorasidenib's efficacy in inhibiting mutant IDH1/2 and 2-HG production in glioma models. It suppresses tumor growth, making it a potential treatment option.
    Clinical evidence: Early clinical trials demonstrate vorasidenib's clinical activity in non-enhancing gliomas. It reduces 2-hydroxyglutarate levels and tumor cell proliferation, with an objective response rate and prolonged progression-free survival. The drug's safety profile is favorable. Challenges and Future Directions: Challenges include identifying predictive biomarkers and optimizing sequencing or combinations with existing therapies. Further research is needed to establish long-term effectiveness, evaluate side effects, and explore combinations with immunotherapy.
    Conclusion: orasidenib significantly advances LGG treatment, targeting a prevalent mutation and slowing tumor growth. Promising preclinical and clinical evidence and manageable side effects suggest its potential impact on LGG management. However, more research, including large trials, is needed to confirm its efficacy and role in treatment.
    Language English
    Publishing date 2024-02-29
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1874-4702
    ISSN (online) 1874-4702
    DOI 10.2174/0118761429290327240222061812
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Meet the authors: Achim Keidel and Elena Conti.

    Keidel, Achim / Conti, Elena

    Molecular cell

    2023  Volume 83, Issue 22, Page(s) 3943–3945

    Abstract: We talk to authors Achim Keidel and Elena Conti about their paper "Concerted structural ...

    Abstract We talk to authors Achim Keidel and Elena Conti about their paper "Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly" (in this issue of Molecular Cell), staying focused on the scientific question while being open to new approaches and their preferred way to celebrate good news.
    MeSH term(s) Exosomes ; RNA
    Chemical Substances RNA (63231-63-0)
    Language English
    Publishing date 2023-11-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1415236-8
    ISSN 1097-4164 ; 1097-2765
    ISSN (online) 1097-4164
    ISSN 1097-2765
    DOI 10.1016/j.molcel.2023.10.027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Virtual Issue on Fast Dynamics and Function of Biomolecules.

    Conti Nibali, Valeria / Paciaroni, Alessandro

    The journal of physical chemistry letters

    2023  Volume 14, Issue 20, Page(s) 4786–4788

    Language English
    Publishing date 2023-05-25
    Publishing country United States
    Document type Editorial
    ISSN 1948-7185
    ISSN (online) 1948-7185
    DOI 10.1021/acs.jpclett.3c01122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A new approach in monitoring blood tests in anti-tumour necrosis factor-α therapies in psoriasis.

    Conti, Andrea / Paolinelli, Matteo

    The British journal of dermatology

    2023  Volume 190, Issue 4, Page(s) 463–464

    MeSH term(s) Humans ; Cost-Benefit Analysis ; Hematologic Tests ; Immunotherapy ; Psoriasis/drug therapy ; Necrosis
    Language English
    Publishing date 2023-12-09
    Publishing country England
    Document type Editorial ; Comment
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1093/bjd/ljad490
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Il bisogno di cure palliative nei pazienti in cure domiciliari attraverso l’applicazione di due algoritmi. Studio osservazionale prospettico.

    Sechi, Lucia / Conti, Alessio / Cirio, Franco / Viottini, Elena

    Assistenza infermieristica e ricerca : AIR

    2024  Volume 42, Issue 4, Page(s) 189–198

    Abstract: The need for palliative care in home care patients. Prospective observational study with the implementation of two algorithms.: Introduction: The early identification of patients with palliative care needs is crucial for defining appropriate care ... ...

    Title translation The need for palliative care in home care patients. Prospective observational study with the implementation of two algorithms.
    Abstract . The need for palliative care in home care patients. Prospective observational study with the implementation of two algorithms.
    Introduction: The early identification of patients with palliative care needs is crucial for defining appropriate care settings and interventions.
    Objective: To detect the need for palliative care in home care patients and to compare two instruments: the SPICT™ and the I-CURPAL-029.
    Methods: All new patients taken on in home care in the South-West and North-West Districts of the ASL Città di Torino between 27/12/2021 and 19/02/2022 were included and assessed with the two systems at intake, at two and six weeks. Data collected on patients: demographic characteristics, diagnosis, reason and duration of admission, reason for discharge, degree of autonomy and mobility, presence of cognitive and behavioural disorders, social support.
    Results: 170 patients were included. At admission, 99 (58.2%) patients with SPICT™ and 84 (49.4%) with I-CURPAL-029 were assessed as needing palliative care; 78 (45.9%) by both instruments. Of the 13 with a need for specialist palliation, 8 were transferred to specialist palliative care. Changes in patients' conditions between controls were detected by both instruments and only affected 12.4% of the sample. SPICT™ and I-CURPAL-029 were sensitive in detecting the need for palliation. SPICT™ was suitable for the home context due to the presence of indicators on caregiving.
    Conclusions: Many patients in home care need palliative care. To support decisions for specialistic care, patients classified as palliative by SPICT™ could be assessed with I-CURPAL-029 to identify the need for specialist palliative care.
    MeSH term(s) Humans ; Palliative Care ; Home Care Services ; Prospective Studies ; Hospitalization ; Patient Discharge
    Language Italian
    Publishing date 2024-01-17
    Publishing country Italy
    Document type Observational Study ; English Abstract ; Journal Article
    ZDB-ID 1480438-4
    ISSN 2038-1778 ; 1120-3803
    ISSN (online) 2038-1778
    ISSN 1120-3803
    DOI 10.1702/4178.41683
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Essential notes: impacted fetal head.

    Baycroft, Alixandra / Conti, Daniel / Sultan, Pervez

    BJA education

    2024  Volume 24, Issue 3, Page(s) 81–83

    Language English
    Publishing date 2024-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2888911-3
    ISSN 2058-5357 ; 2058-5349
    ISSN (online) 2058-5357
    ISSN 2058-5349
    DOI 10.1016/j.bjae.2023.12.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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