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Article: Exceptional response to immunotherapy monotherapy in a patient with an unfavorable subset of cancer of unknown primary.

Huang, Xiangzhong / Ren, Dongqing / Sun, Qiulian / Xu, Xinjian / Ding, Yiwen

Quantitative imaging in medicine and surgery

2023 Volume 13, Issue 12, Page(s) 8832–8838

Language	English
Publishing date	2023-10-09
Publishing country	China
Document type	Journal Article
ZDB-ID	2653586-5
ISSN	2223-4306 ; 2223-4292
ISSN (online)	2223-4306
ISSN	2223-4292
DOI	10.21037/qims-23-284
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Meta-analysis of cryoablation versus radiofrequency ablation in the treatment of malignant liver tumors.

Huang, Xiangzhong / Xu, Xinjian / Du, Hongtao / Sun, Qiulian / Wu, Minyu

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group

2024 Volume 41, Issue 1, Page(s) 2300347

Abstract: Objective: A meta-analysis was conducted to assess the efficacy and safety of cryoablation (CRA) compared with radiofrequency ablation (RFA).: Methods: A systematic search of PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and VIP databases was ... ...

Abstract	Objective: A meta-analysis was conducted to assess the efficacy and safety of cryoablation (CRA) compared with radiofrequency ablation (RFA). Methods: A systematic search of PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and VIP databases was conducted to identify clinical controlled studies comparing CRA versus RFA for hepatic malignancies up to July 2022. The meta-analysis was performed using RevMan 5.3. Results: A comprehensive analysis was conducted on 8 clinical controlled studies involving a total of 943 patients. There were no significant differences in the incidence of complications, complete ablation of lesions, local recurrence, and 1-year survival between the CRA and RFA groups (OR = 0.98, 95%CI: 0.61-1.55, Conclusion: The efficacy and safety profile of CRA was comparable to that of RFA in the context of ablation therapy for hepatic malignancies. These findings suggested that CRA may be a valuable alternative to RFA in the treatment of hepatic malignancies.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular ; Cryosurgery ; Liver Neoplasms/surgery ; Radiofrequency Ablation
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review
ZDB-ID	632526-9
ISSN	1464-5157 ; 0265-6736
ISSN (online)	1464-5157
ISSN	0265-6736
DOI	10.1080/02656736.2023.2300347
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Article: Effect of Different Drying Methods on the Quality and Nonvolatile Flavor Components of

Shen, Qiulian / He, Zedong / Ding, Yangyue / Sun, Liping

Foods (Basel, Switzerland)

2023 Volume 12, Issue 3

Abstract: Different drying methods affect the quality of foods. The aim of this study is to explore the effects of seven drying methods, including hot air drying at 60 °C and 80 °C, ultrasound-assisted hot air drying at 60 °C and 80 °C, microwave drying, vacuum ... ...

Abstract	Different drying methods affect the quality of foods. The aim of this study is to explore the effects of seven drying methods, including hot air drying at 60 °C and 80 °C, ultrasound-assisted hot air drying at 60 °C and 80 °C, microwave drying, vacuum microwave drying, and vacuum freeze-drying, on the quality and nonvolatile flavor components of
Language	English
Publishing date	2023-02-03
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12030676
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Article ; Online: Genetic improvement of duration of fertility in chickens and its commercial application for extending insemination intervals.

Wang, Qunpu / Wang, Qiulian / Wang, Chaoyi / Sun, Congjiao / Yang, Ning / Wen, Chaoliang

Poultry science

2024 Volume 103, Issue 3, Page(s) 103438

Abstract: The growth rate of chickens has made remarkable progress in recent decades through continuous breeding efforts. However, this advancement has also led to a decline in fertility among commercially bred chickens. Therefore, it is crucial to understand and ... ...

Abstract	The growth rate of chickens has made remarkable progress in recent decades through continuous breeding efforts. However, this advancement has also led to a decline in fertility among commercially bred chickens. Therefore, it is crucial to understand and improve factors that influence fertility to ensure the continued success of the industry. Here, we conduct a 3-generation selection experiment within 2 purebred female lines, with the aim of increasing the duration of fertility (DF). Duration of fertility refers to the length of time hens remain capable of producing fertilized eggs and is a crucial factor that directly impacts chick output. The results showed that significant genetic progress was achieved in embryo survival rates and the fertility duration day during both the peak and late laying periods. Moreover, after 3 generations of selective breeding, the disparities in embryo survival and chick health rates from setting eggs between 8-d and 5-d insemination intervals in the grandparent stock were significantly reduced. The rates decreased from 1.83% and 2.39 to 0.72% and 0.33%, respectively. Surprisingly, the hatching performances of hens with an 8-d interval were comparable to those hens that had not undergone genetic selection for DF and had a 5-d interval. We further discussed the possibility of extending the insemination interval to 8 d in parent stock for commercial practices. The parental populations exhibited remarkable performance in terms of percentages of embryo survival and healthy chicks from the setting eggs, with rates exceeding 94 and 90%, respectively. Thus, it can be inferred that an extended insemination interval is feasible by genetic selection for DF. These findings will provide valuable insights into the efficacy of genetic selection in enhancing DF and its practical application in commercial breeding programs.
MeSH term(s)	Animals ; Female ; Chickens/genetics ; Ovum ; Fertility/genetics ; Health Status ; Zygote
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Journal Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2024.103438
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Article ; Online: Effect of Different Drying Methods on the Quality and Nonvolatile Flavor Components of Oudemansiella raphanipes

Shen, Qiulian / He, Zedong / Ding, Yangyue / Sun, Liping

Foods. 2023 Feb. 03, v. 12, no. 3

2023

Abstract	Different drying methods affect the quality of foods. The aim of this study is to explore the effects of seven drying methods, including hot air drying at 60 °C and 80 °C, ultrasound-assisted hot air drying at 60 °C and 80 °C, microwave drying, vacuum microwave drying, and vacuum freeze-drying, on the quality and nonvolatile flavor components of Oudemansiella raphanipes. The vacuum freeze-drying resulted in minimal collapse, mild shrinkage at the macroscopic level, and the formation of uniform pores at the microscopic level on the surfaces of O. raphanipes mushrooms. In addition, vacuum freeze-drying can improve the color attributes of the mushrooms. Therefore, the appearance and shape of vacuum freeze-drying treated O. raphanipes were closest to those of fresh mushrooms. We found that ultrasound-assisted treatment can effectively shorten the drying time of O. raphanipes. The drying time of ultrasound-assisted hot air drying at 60 °C was 20% shorter than that of hot air drying at 60 °C, and the drying time of ultrasound-assisted hot air drying at 80 °C was 37.5% shorter than that of hot air drying at 80 °C. The analysis of the nonvolatile flavor components showed that the ultrasound-assisted hot air drying at 60 °C of the O. raphanipes sample had the highest content of free amino acids (83.78 mg/g) and an equivalent umami concentration value (1491.33 monosodium glutamate/100 g). The vacuum freeze-drying treated O. raphanipes had the highest 5′-nucleotide content of 2.44 mg/g. Therefore, vacuum freeze-drying and ultrasound-assisted hot air drying at 60 °C, followed by vacuum microwave drying, might protect the flavor components of O. raphanipes to the greatest extent. However, microwave drying, hot air drying at 80 °C, and ultrasound-assisted hot air drying at 80 °C could destroy the flavor components of O. raphanipes during drying. The results of this study provided data support for the industrial production of dried O. raphanipes.
Keywords	air ; color ; freeze drying ; shrinkage ; ultrasonic treatment ; umami
Language	English
Dates of publication	2023-0203
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods12030676
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Isolation, taste characterization and molecular docking study of novel umami peptides from Lactarius volemus (Fr.).

Shen, Qiulian / Sun, Liping / He, Zedong / Xie, Jinxiang / Zhuang, Yongliang

Food chemistry

2022 Volume 401, Page(s) 134137

Abstract: This study aimed to understand the tasty flavor of wild Lactarius volemus (Fr.). The umami peptides from its aqueous extraction were purified by ultrafiltration, Sephadex G-25 gel filtration chromatography, and reversed-phase high-performance liquid ... ...

Abstract	This study aimed to understand the tasty flavor of wild Lactarius volemus (Fr.). The umami peptides from its aqueous extraction were purified by ultrafiltration, Sephadex G-25 gel filtration chromatography, and reversed-phase high-performance liquid chromatography. Sensory evaluation was used to identify the peptide fraction with the intense umami taste, and the peptides in the fraction were identified. Four umami peptides, namely EVAEALDAPKTT, AVLEEAQKVELK, AEDLSTLR, and KVDVDSLK, were virtually selected by molecular docking and umami taste active fragment frequency. The sensory evaluation and electronic tongue revealed that four screened peptides had umami taste features with umami identification thresholds in the range of 0.0625-0.250 mg/mL. Molecular docking results showed that the four umami peptides could be embedded into the binding pocket of the taste receptor T1R3 cavity. The major interactions forces were hydrogen bonding and hydrophobic interactions, and the key sites for T1R3 binding were Glu217, Glu148, and Glu45.
MeSH term(s)	Taste ; Molecular Docking Simulation ; Peptides/chemistry ; Basidiomycota/metabolism ; Receptors, G-Protein-Coupled/metabolism
Chemical Substances	Peptides ; Receptors, G-Protein-Coupled
Language	English
Publishing date	2022-09-07
Publishing country	England
Document type	Journal Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2022.134137
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Article: Isolation, taste characterization and molecular docking study of novel umami peptides from Lactarius volemus (Fr.)

Shen, Qiulian / Sun, Liping / He, Zedong / Xie, Jinxiang / Zhuang, Yongliang

Food chemistry. 2023 Feb. 01, v. 401

2023

Abstract	This study aimed to understand the tasty flavor of wild Lactarius volemus (Fr.). The umami peptides from its aqueous extraction were purified by ultrafiltration, Sephadex G-25 gel filtration chromatography, and reversed-phase high-performance liquid chromatography. Sensory evaluation was used to identify the peptide fraction with the intense umami taste, and the peptides in the fraction were identified. Four umami peptides, namely EVAEALDAPKTT, AVLEEAQKVELK, AEDLSTLR, and KVDVDSLK, were virtually selected by molecular docking and umami taste active fragment frequency. The sensory evaluation and electronic tongue revealed that four screened peptides had umami taste features with umami identification thresholds in the range of 0.0625–0.250 mg/mL. Molecular docking results showed that the four umami peptides could be embedded into the binding pocket of the taste receptor T1R3 cavity. The major interactions forces were hydrogen bonding and hydrophobic interactions, and the key sites for T1R3 binding were Glu217, Glu148, and Glu45.
Keywords	Lactarius ; electronic tongue ; food chemistry ; gel chromatography ; hydrogen ; hydrophobicity ; peptides ; reversed-phase high performance liquid chromatography ; sensory evaluation ; taste ; taste receptors ; ultrafiltration ; umami
Language	English
Dates of publication	2023-0201
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	243123-3
ISSN	1873-7072 ; 0308-8146
ISSN (online)	1873-7072
ISSN	0308-8146
DOI	10.1016/j.foodchem.2022.134137
Database	NAL-Catalogue (AGRICOLA)

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Article: CT-Guided

Xu, Xinjian / Ding, Yiwen / Pan, Tianfan / Gao, Feng / Huang, Xiangzhong / Sun, Qiulian

Cancer management and research

2021 Volume 13, Page(s) 3317–3326

Abstract: Purpose: To investigate the efficacy and safety of CT-guided : Methods: Nineteen patients with TACE-refractory HCC treated with CT-guided : Results: Twenty-one tumours were treated with CT-guided : Conclusion: Our preliminary clinical ... ...

Abstract	Purpose: To investigate the efficacy and safety of CT-guided Methods: Nineteen patients with TACE-refractory HCC treated with CT-guided Results: Twenty-one tumours were treated with CT-guided Conclusion: Our preliminary clinical experience demonstrated that CT-guided
Language	English
Publishing date	2021-04-15
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2508013-1
ISSN	1179-1322
ISSN	1179-1322
DOI	10.2147/CMAR.S305422
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Evolution of Computed Tomography Manifestations in Five Patients Who Recovered from Coronavirus Disease 2019 (COVID-19) Pneumonia.

Sun, Qiulian / Xu, Xinjian / Xie, Jicheng / Li, Jingjing / Huang, Xiangzhong

Korean journal of radiology

2020 Volume 21, Issue 5, Page(s) 614–619

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus ; Coronavirus Infections ; Disease Outbreaks ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Tomography
Keywords	covid19
Language	English
Publishing date	2020-03-13
Publishing country	Korea (South)
Document type	Letter ; Comment
ZDB-ID	2046981-0
ISSN	2005-8330 ; 1229-6929
ISSN (online)	2005-8330
ISSN	1229-6929
DOI	10.3348/kjr.2020.0157
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Article: Evolution of Computed Tomography Manifestations in Five Patients Who Recovered from Coronavirus Disease 2019 (COVID-19) Pneumonia

Sun, Qiulian / Xu, Xinjian / Xie, Jicheng / Li, Jingjing / Huang, Xiangzhong

Korean J Radiol

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #8673
Database	COVID19

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