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  1. Article ; Online: Corrigendum to "Betaine prevents and reverses the behavioral deficits and synaptic dysfunction induced by repeated ketamine exposure in mice" by Shao-Tsu Chen [Biomed. Pharmacother. 144 (2021) 112369].

    Chen, Shao-Tsu / Hsieh, Chung-Pin / Lee, Mei-Yi / Chen, Liao-Chen / Huang, Chien-Min / Chen, Hwei-Hsien / Chan, Ming-Huan

    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

    2023  Volume 163, Page(s) 114840

    Language English
    Publishing date 2023-05-05
    Publishing country France
    Document type Published Erratum
    ZDB-ID 392415-4
    ISSN 1950-6007 ; 0753-3322 ; 0300-0893
    ISSN (online) 1950-6007
    ISSN 0753-3322 ; 0300-0893
    DOI 10.1016/j.biopha.2023.114840
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.198: Show issues Location:
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  2. Article: Driving forces of grassland vegetation changes in Chen Barag Banner, Inner Mongolia

    Yan, Xiaoxiao / Li, Jing / Shao, Yang / Hu, Zhenqi / Yang, Zhen / Yin, Shouqiang / Cui, lvyuan

    GIScience & remote sensing. 2020 Aug. 17, v. 57, no. 6

    2020  

    Abstract: ... balance in Chen Barag Banner and other areas facing similar challenges. ...

    Abstract Inner Mongolia is an important ecological zone of northern China and 67% of its land area is grassland. This ecologically fragile region has experienced significant vegetation degradation during the last decades. Although the spatial extents and rates of vegetation change have previously been characterized through various remote sensing and GIS studies, the underlying driving factors of vegetation changes are still not well understood. In this study, we first used time-series MODIS NDVI data from 2000 to 2016 to characterize the temporal trend of vegetation changes. These vegetation change trends were compared with climate and socioeconomic variables to determine the potential drivers. We used a set of statistical methods, including multiple linear regression (MLR), spatial correlation analysis, and partial least squares (PLS) regression analyzes, to quantify the spatial distribution of the driving forces and their relative importance to vegetation changes. Results show that the main driving factors and their impact magnitude (weight) are in the order of human activities (r = -0.785, p < 0.01, VIP = 1.37), precipitation (r = 0.541, p < 0.05, VIP = 0.89), temperature (r = -0.319, p > 0.05 VIP = 0.59). The area affected by human activities was 10.57%. Specific human activities, such as coal mining and grazing were negatively associated with vegetation cover, while eco-engineering projects had positive impacts. This study provided thorough quantification of driving forces of vegetation change and enhanced our understanding of their interactions. Our integrated geospatial-statistical approach is particularly important for sustainable development of ecosystem balance in Chen Barag Banner and other areas facing similar challenges.
    Keywords climate ; coal ; ecosystems ; grasslands ; humans ; sustainable development ; temperature ; time series analysis ; vegetation cover ; China
    Language English
    Dates of publication 2020-0817
    Size p. 753-769.
    Publishing place Taylor & Francis
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2209042-3
    ISSN 1943-7226 ; 1548-1603
    ISSN (online) 1943-7226
    ISSN 1548-1603
    DOI 10.1080/15481603.2020.1794395
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Apoptosis of human pancreatic carcinoma cell-1 cells induced by Yin Chen Hao Decoction.

    Zhou, Hai-Bo / Chen, Jing-Ming / Shao, Li-Ming / Chen, Zhi-Gang

    World journal of gastroenterology

    2015  Volume 21, Issue 27, Page(s) 8352–8357

    Abstract: ... expression induced by Yin Chen Hao Decoction (YCHD).: Methods: The cell growth inhibitory rate was ...

    Abstract Aim: To evaluate human pancreatic carcinoma cell line (PANC-1) cells apoptosis and Bcl-2 and Bax expression induced by Yin Chen Hao Decoction (YCHD).
    Methods: The cell growth inhibitory rate was determined by MTT assay. Apoptosis of PANC-1 cells before and after treatment with YCHD was determined by TUNEL staining. Expression of the apoptosis-associated genes, Bcl-2 and Bax, was detected by immunohistochemical staining and reverse transcription -PCR.
    Results: YCHD inhibited the growth of PANC-1 cells. Following treatment with YCHD for 24-96 h, the apoptotic rate of PANC-1 cells increased with time. In addition, the positive rate of Bcl-2 protein expression decreased in a time-dependent manner, whereas the positive rate of Bax protein expression increased in a time-dependent manner. Following treatment of with YCHD for 24-96h, expression of BAX mRNA increased gradually and BCL-2 mRNA reduced gradually with time.
    Conclusion: YCHD induces apoptosis of PANC-1 cells mediated in part via up-regulation of BAX and down-regulation of BCL-2.
    MeSH term(s) Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis/drug effects ; Carcinoma/drug therapy ; Carcinoma/genetics ; Carcinoma/metabolism ; Carcinoma/pathology ; Cell Line, Tumor ; Drugs, Chinese Herbal/pharmacology ; Gene Expression Regulation, Neoplastic ; Humans ; Immunohistochemistry ; In Situ Nick-End Labeling ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/genetics ; Pancreatic Neoplasms/metabolism ; Pancreatic Neoplasms/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; RNA, Messenger/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
    Chemical Substances Antineoplastic Agents, Phytogenic ; BAX protein, human ; BCL2 protein, human ; Drugs, Chinese Herbal ; Proto-Oncogene Proteins c-bcl-2 ; RNA, Messenger ; bcl-2-Associated X Protein ; yinchenhao
    Language English
    Publishing date 2015-07-21
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v21.i27.8352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6039: Show issues Location:
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  4. Book: Chen Du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Author's details zhu bian Ren Jianshu; fu zhu bian Li Yinde, Shao Hua
    Language Chinese
    Size 2, 9, 459 S., port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  5. Book: Chen Du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Author's details zhu bian Ren Jianshu; fu zhu bian Li Yinde, Shao Hua
    Language Chinese
    Size 16, 352 S., port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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  6. Book: Chen Du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Author's details zhu bian Ren Jianshu; fu zhu bian Li Yinde, Shao Hua
    Language Chinese
    Size 13, 499 S., port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

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  7. Book: Chen Du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Author's details zhu bian Ren Jianshu; fu zhu bian Li Yinde, Shao Hua
    Language Chinese
    Size 14, 552 S., port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

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  8. Book: Chen Du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Author's details zhu bian Ren Jianshu; fu zhu bian Li Yinde, Shao Hua
    Language Chinese
    Size 5, 400 S., port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    Database Former special subject collection: coastal and deep sea fishing

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    Inter-library loan at ZB MED

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  9. Book: Chen du xiu zhu zuo xuan bian

    Chen, Duxiu / Ren, Jianshu / Li, Yinde / Shao, Hua

    2010  

    Title translation Selections. 2009
    Author's details zhu bian ren jian shu; fu zhu bian li yin de, shao hua
    Keywords Chinese literature
    Language Chinese
    Size 6 v, port, 24 cm
    Edition Di 1 ban
    Publisher Shang hai ren min chu ban she
    Publishing place Shang hai
    Document type Book
    ISBN 7208081417 ; 9787208081413
    Database Former special subject collection: coastal and deep sea fishing

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  10. Article ; Online: The Hypolipidemic Effect of Dalbergia odorifera T. C. Chen Leaf Extract on Hyperlipidemic Rats and Its Mechanism Investigation Based on Network Pharmacology

    Hui Mei / Huiming Hu / Yanni Lv / Guangqiang Ma / Fangrui Tang / Zhou Hong / Feng Shao

    Evidence-Based Complementary and Alternative Medicine, Vol

    2021  Volume 2021

    Abstract: ... odorifera T. C. Chen leaf extract. Methods. The hypolipidemic effect of D. odorifera leaf extract was ...

    Abstract Objective. The aim of this study was to explore the hypolipidemic effect and mechanism of Dalbergia odorifera T. C. Chen leaf extract. Methods. The hypolipidemic effect of D. odorifera leaf extract was investigated using a hyperlipidemic rat model. Then, its mechanism was predicted using network pharmacology methods and verified using western blotting. Results. Compared with the levels in the model group, the serum levels of triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) decreased significantly, whereas the serum level of high-density lipoprotein cholesterol (HDL-C) increased dramatically after treatment with the extract. The degrees of hepatocyte steatosis and inflammatory infiltration were markedly attenuated in vivo. Then, its hyperlipidemic mechanism was predicted using network pharmacology-based analysis. Thirty-five key targets, including sterol regulatory element-binding protein cleavage-activating protein (SCAP), sterol regulatory element-binding protein-2 (SREBP-2), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), low-density lipoprotein receptor (LDLR), and ten signaling pathways, were associated with hyperlipidemia. Finally, it was verified that the extract downregulated the protein levels of SCAP, SREBP-2, and HMGCR, and upregulated protein levels of LDLR. Conclusion. These findings provided additional evidence of the hypolipidemic effect of D. odorifera leaf extract.
    Keywords Other systems of medicine ; RZ201-999
    Subject code 616
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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