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Article ; Online: Detection of Epstein-Barr virus and Hashimoto’s autoimmune in patients with a thyroid disorder

AL-Rammahi Anware Abd Hashim Auda / AL-Khilkhali Huda Jameel Baker

BIO Web of Conferences, Vol 65, p

2023 Volume 05046

Abstract: Hypothyroidism’s most common cause is Hashimoto’s thyroiditis (HT). Because Epstein-Barr virus is ... the relationship between Epstein-Barr virus (EBV) and Hashimoto’s autoimmune disease in patients with a thyroid ...

Abstract	Hypothyroidism’s most common cause is Hashimoto’s thyroiditis (HT). Because Epstein-Barr virus is a common pathogen that causes autoimmune diseases to be prevalent worldwide and because it stays in the body for the duration of life, which explains why autoimmune diseases have a chronic course and are frequently accompanied by symptomatic exacerbations, the aim of this research is to determine the relationship between Epstein-Barr virus (EBV) and Hashimoto’s autoimmune disease in patients with a thyroid disorder. 120 samples were collected from the governorate of Najaf (60 with thyroidectomy and 60 as controls) to identify the presence of EBV. The proportion of patients with EBV was 27 (45%) compared to the control group, which was all negative. This study detects the autoimmune disease (Hashimoto thyroiditis) in all 160 samples using the anti-thyroperoxidase (TPO) test, which yields a positive result in 40% of patients (24), a negative result in 60% (36), and a negative result in 100% (60) of control samples.
Keywords	Microbiology ; QR1-502 ; Physiology ; QP1-981 ; Zoology ; QL1-991
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
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Article: A Case Report of Acute Severe Necrotizing Pancreatitis following the Johnson & Johnson Vaccine against the Novel SARS-CoV-2.

Bangolo, Ayrton I / Akhter, Mahabuba / Auda, Auda / Akram, Rahina / Nagesh, Vignesh K / Athem, Donnee / Thomas, Reenu / Tibalan, Ligaya / Trivedi, Mansi / Mushtaq, Saima / Singh, Neha / Bagale, Pracheta / Arana, Georgemar V / Khan, Tayyaba / Sharma, Shelja / Mynedi, Swetha / Patel, Dhara D / Saini, Mandeep / Chinthakuntla, Madhurya R /

Ahmed, Kareem / Gad, Mary / Gondhi, Srikara Dheer D R / Arana, Georgemar / Gurumoorthy, Rohini B / Weissman, Simcha

Case reports in infectious diseases

2023 Volume 2023, Page(s) 9965435

Abstract: Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute ... ...

Abstract	Acute pancreatitis is an inflammatory condition, which is a leading gastrointestinal cause of hospitalization in the United States. Several conditions are associated with acute pancreatitis. More recently, there have been a few cases reported of acute pancreatitis following the Pfizer-BioNTech COVID-19 mRNA vaccine. To our knowledge, no cases of acute pancreatitis have been yet reported following the Johnson & Johnson's Janssen COVID-19 vaccine (J& J vaccine). Herein we report a 34-year-old male with no significant past medical history admitted with acute necrotizing pancreatitis, the day following the receipt of the J&J vaccine. Based on the Naranjo and the modified Naranjo scale, the patient met the requirements for probable drug induced pancreatitis. This case report has the objective to raise awareness of a potentially severe side effect of the J&J vaccine. We hope to use this case to support screening all patients for previous history of acute pancreatitis before administration of the J& J vaccine.
Language	English
Publishing date	2023-03-22
Publishing country	Egypt
Document type	Case Reports
ZDB-ID	2627642-2
ISSN	2090-6633 ; 2090-6625
ISSN (online)	2090-6633
ISSN	2090-6625
DOI	10.1155/2023/9965435
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Article ; Online: Parasiticidal Efficacy of a New Formulation of Silver Nanoparticles on Trichinella spiralis in vitro

Noha M. Taha / Shimaa Abdel-Radi / Fady S. Youssef / Hend M. Auda / Mohamed M. El-Bahy / Reem M. Ramadan

Journal of Advanced Veterinary Research, Vol 12, Iss

2022 Volume 4

Abstract: ... significant difference (p ≤ .05) between the recorded mortalities and DNA damage between that obtained using ...

Abstract	This research illustrates the development of a new sliver nanoparticle (Ag-NPs) formulation. Its shape, size, solubility, and stability were characterized using Scanning Electron Microscope (SEM 3D), Transmission Electron Microscope (TEM 2D), Atomic Force Microscope (AFM), and Zeta size and Zeta potential. Exposure of Trichinella spiralis adult worms to 3, 6, 9 and 12 ppm of Ag-NPs each for 3,6,12 and 24 h. In vitro revealed a direct relation between mortalities and the tested drug concentration and exposure time. Anti- T. spiralis effect of Ag-NPs was evaluated by assessing mortality rate and damage in DNA by comet assay and by SEM analysis. Mean mortalities increased from 6.66% after exposure to 3.0 ppm/1 h to 100% after exposure to 12.0 ppm/12 h. The calculated LC50 was 3.0 ppm/10 h, 6 ppm/6 h, 9.0 ppm/4 h and 12.0 ppm/ 3.30 h, while LC100 was 9.0 ppm/24 h and 12.0 ppm/12 h. DNA genotoxic damage of dead worms was directly related to Ag-NPs concentrations for 12h using comet assay as expressed by variations in the percentage of DNA in the tail segment, tail length (μm), tail moment (μm), and olive tail moment. No significant difference (p ≤ .05) between the recorded mortalities and DNA damage between that obtained using the Ag-NPs LC100 and that recorded using Albendazole (50 mg/kg B.W.) for 12 h. SEM images on dead worms revealed clear morphological alteration, multiple vesicles, and blebs, detachment of the epidermis and the sub-epidermal layer with partial sloughing of the cuticle, and loss of normal creases, ridges, and annulations. These morphological alterations were directly related to the concentration of the tested Ag-NPs. The tested new formulation of Ag-NPs appears to be effective in the control of Trichinellosis as an alternative to other resistant drugs.
Keywords	Trichinella spiralis ; Nano-Silver ; DNA damage ; Electron microscopy ; Veterinary medicine ; SF600-1100
Subject code	621
Language	English
Publishing date	2022-09-01T00:00:00Z
Publisher	Assiut University
Document type	Article ; Online
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Article: Interaction between age and gender on survival outcomes in extramedullary multiple myeloma over the past two decades.

Bangolo, Ayrton I / Fwelo, Pierre / Trivedi, Chinmay / Sagireddy, Sowmya / Aljanaahi, Hamed / Auda, Auda / Mohamed, Maryama / Onyeka, Sonia / Fisher, Miriam / Thapa, Jyoti / Tabucanon, Erwin J / Georgiev, Lyuben / Wishart, Annetta / Kumari, Shilpee / Erikson, Conrad / Bangura, Mary / Paddy, Orent / Madhukar, Rashmi / Gomez, Eugenio L /

Rathod, Joshua / Naria, Mansi / Hajal, Basel / Awadhalla, Mohammad / Siegel, David / Parmar, Harsh / Biran, Noa / Vesole, David H / Phull, Pooja / Weissman, Simcha

World journal of clinical oncology

2023 Volume 14, Issue 4, Page(s) 179–189

Abstract: Background: Extramedullary multiple myeloma (MM) (EMM) is a rare and aggressive subentity of MM that can be present at diagnosis or develop anytime during the disease course. There is a paucity of data on the clinical characteristics and overall ... ...

Abstract	Background: Extramedullary multiple myeloma (MM) (EMM) is a rare and aggressive subentity of MM that can be present at diagnosis or develop anytime during the disease course. There is a paucity of data on the clinical characteristics and overall epidemiology of EMM. Furthermore, there is a scarcity of data on how the interaction of age and gender influences the survival of EMM. Aim: To evaluate the clinical characteristics of patients with EMM over the past 2 decades and to identify epidemiologic characteristics that may impact overall prognosis. Methods: A total of 858 patients diagnosed with EMM, between 2000 and 2017, were ultimately enrolled in our study by retrieving the Surveillance, Epidemiology, and End Results database. We analyzed demographics, clinical characteristics, and overall mortality (OM) as well as cancer-specific mortality (CSM) of EMM. Variables with a Results: From a sample of 858 EMM, the male gender (63.25%), age range 60-79 years (51.05%), and non-Hispanic whites (66.78%) were the most represented. Central Nervous System and the vertebral column was the most affected site (33.10%). Crude analysis revealed higher OM in the age group 80+ [HR = 6.951, 95% confidence interval (95%CI): 3.299-14.647, Conclusion: EMM is a rare entity. To our knowledge, there is a scarcity of data on the clinical characteristics and prognosis factors of patients with extramedullary multiple myeloma. In this retrospective cohort, using a United States-based population, we found that age, marital status, and tumor site were independent prognostic factors. Furthermore, we found that age and gender did not interact to influence the mortality of patients with EMM.
Language	English
Publishing date	2023-04-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	2587357-X
ISSN	2218-4333
ISSN	2218-4333
DOI	10.5306/wjco.v14.i4.179
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Article ; Online: Effects of hydrological regime and land use on in-stream Escherichia coli concentration in the Mekong basin, Lao PDR.

Nakhle, Paty / Ribolzi, Olivier / Boithias, Laurie / Rattanavong, Sayaphet / Auda, Yves / Sayavong, Saysongkham / Zimmermann, Rosalie / Soulileuth, Bounsamay / Pando, Anne / Thammahacksa, Chanthamousone / Rochelle-Newall, Emma J / Santini, William / Martinez, Jean-Michel / Gratiot, Nicolas / Pierret, Alain

Scientific reports

2021 Volume 11, Issue 1, Page(s) 3460

Abstract: In the basin of Mekong, over 70 million people rely on unimproved surface water for their domestic requirements. Surface water is often contaminated with fecal matter and yet little information exists on the underlying mechanisms of fecal contamination ... ...

Abstract	In the basin of Mekong, over 70 million people rely on unimproved surface water for their domestic requirements. Surface water is often contaminated with fecal matter and yet little information exists on the underlying mechanisms of fecal contamination in tropical conditions at large watershed scales. Our objectives were to (1) investigate the seasonality of fecal contamination using Escherichia coli as fecal indicator bacteria (FIB), and (2) establish links between the fecal contamination in stream water and its controlling factors (hydrology and land use). We present the results of (1) a sampling campaign at the outlet of 19 catchments across Lao PDR, in both the dry and the rainy seasons of 2016, and (2) a 10-day interval monitoring conducted in 2017 and 2018 at three point locations of three rivers (Nam Ou, Nam Suang, and Mekong) in northern Lao PDR. Our results show the presence of fecal contamination at most of the sampled sites, with a seasonality characterized by higher and extreme E. coli concentrations occurring during the rainy season. The highest E. coli concentrations, strongly correlated with total suspended sediment concentrations, were measured in catchments dominated by unstocked forest areas, especially in mountainous northern Lao PDR and in Vientiane province.
Language	English
Publishing date	2021-02-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-82891-0
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Article: The needle biopsy should replace open excisional biopsy.

Auda, S P

Annals of surgical oncology

1996 Volume 3, Issue 3, Page(s) 325

MeSH term(s)	Biopsy ; Biopsy, Needle ; Breast/pathology ; Breast Neoplasms/pathology ; Female ; Humans
Language	English
Publishing date	1996-05
Publishing country	United States
Document type	Comment ; Letter
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1007/bf02306290
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Article ; Online: Comparative study of embedded functionalised MWCNTs and GO in Ultrafiltration (UF) PVC membrane: interaction mechanisms and performance

Sadiq, Amna J. / Awad, Eman S. / Shabeeb, Kadhum M. / Khalil, Bassam I. / Al-Jubouri, Sama M. / Sabirova, T. M. / Tretyakova, N. A. / Majdi, Hasan Shaker / Alsalhy, Qusay F. / Braihi, Auda J.

International Journal of Environmental Analytical Chemistry. 2023 Jan. 26, v. 103, no. 2 p.415-436

2023

Abstract: This work presents the development of polyvinyl chloride/functionalised multi-carbon nanotube (PVC/F-MWCNT) membranes and PVC/graphene oxide (PVC/GO) membranes for the improved removal of chemical oxygen demand (COD) from actual petroleum wastewater. ... ...

Abstract	This work presents the development of polyvinyl chloride/functionalised multi-carbon nanotube (PVC/F-MWCNT) membranes and PVC/graphene oxide (PVC/GO) membranes for the improved removal of chemical oxygen demand (COD) from actual petroleum wastewater. Also, this work for the first time presents the proposed interaction mechanism between the contents of PVC/GO and PVC/F-MWCNT membranes as well as the interaction mechanism of each composite membrane with water molecules. The effect of both F-MWCNT and GO content on the characteristics and performance of the PVC/F-MWCNT membrane and PVC/GO membrane were studied. Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscope (SEM), atomic force microscopy (AFM), contact angle (CA), differential scanning calorimetry (DSC), porosity and tensile strength were used to examine the properties of F-MWCNT, GO, PVC/F-MWCNT and PVC/GO membranes. The composite membranes’ performance was studied by measuring the rejection of chemical oxygen demand (COD) and mass flux. It was found that F-MWCNTs and GO played significant roles in the membranes’ structural morphology. A significant improvement was obtained in the CA, porosity and tensile strength of the membranes by embedding the PVC casting solution with 0.12 wt% of each F-MWCNTand GO. The PVC/F-MWCNTs membrane showed higher performance in term of mass flux and COD rejection that reached 88.9%, which makes using a PVC/F-MWCNTs membrane preferable to remove COD from petroleum wastewater.
Keywords	Fourier transform infrared spectroscopy ; X-ray diffraction ; analytical chemistry ; asymmetric membranes ; atomic force microscopy ; calorimetry ; chemical oxygen demand ; comparative study ; contact angle ; graphene oxide ; mass transfer ; nanotubes ; petroleum ; poly(vinyl chloride) ; porosity ; tensile strength ; ultrafiltration ; wastewater ; Interaction mechanism ; MWCNTs ; modified membrane ; flat-sheet membrane ; COD removal
Language	English
Dates of publication	2023-0126
Size	p. 415-436.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	120480-4
ISSN	1029-0397 ; 0306-7319 ; 0092-9085
ISSN (online)	1029-0397
ISSN	0306-7319 ; 0092-9085
DOI	10.1080/03067319.2020.1858073
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Article ; Online: A Novel Genetic Determination of a Lectin Gene in Iraqi

Muslim, Sahira Nsayef / Al-Kadmy, Israa M S / Auda, Ibtesam Ghadban / Mohammed Ali, Alaa Naseer / Al-Jubori, Sawsan Sajid

Journal of AOAC International

2018 Volume 101, Issue 5, Page(s) 1623–1630

Abstract: ... for Klebsiella pneumonia, 46.7% for P. stutzeri and 53% for A. baumannii. These results suggested that lectin has ...

Abstract	Background: Lectin was initially called hemagglutinin or agglutinin because of its capacity to agglutinate human as well as human erythrocytes. They are a heterogeneous group of proteins or glycoproteins of nonimmune origin. Because of their chemical properties, they have become a useful tool in several fields such as immunology, cell biology, molecular biology, membrane structure, pharmacology, cancer research, clinical chemistry, and genetic engineering. Objective: The wide applications of lectins users urged the need to isolate lectins from a new strain of bacteria can produce new and high yield of lectin because the current production of lectin from Pseudomonas spp. is very expensive. The goal of this study was to screen the ability of Acinetobacter baumannii isolates to produce lectin and detection of its phenotypic and genotypic profiles and detection of lectin ability to inhibit ofbiofilm formation. Methods: Fifty-one isolates from different sources were collected and detected genetically by using the recA gene. Phenotypic detection of lectin by using semi-quantitative analysis and quantitative analysis in microtiter plate. Genotypic detection of lectin by designed lec gene and used PCR technique. The lectin was extracted by using glass beads and purified by chromatographyic technique followed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis for determination the molecular size of lectin and finally detection the spectrum of biofilm inhibition by the purified lectin toward biofilm producers. Results: Of 51 A. baumannii isolates, 17 (33.3%) have been found to produce lectin. Ten of 17 were sequenced, of which 2 were submitted and tested by the gene bank National Center for Biotechnology Information (NCBI), and accession numbers (KX766405.1 and KX766406.1) were obtained. These 17 isolates were phenotypically and genotypically positive for lectin and showed different lec gene expression in semi-quantitative and quantitative analysis. The activities ranged between 4-128 U/mL. Lectin purified by ammonium sulfate precipitation was used to inhibit biofilm formation. We found reduction at three different types of bacteria ranging from 26% for Klebsiella pneumonia, 46.7% for P. stutzeri and 53% for A. baumannii. These results suggested that lectin has a promising application as an antibiofilm agent to combat the growing number of multidrug-resistant pathogen-associated infections. Conclusions: Lectin has been detected recently in A. baumannii, but the genetic property of this lectin has not yet been fully studied. In our study, we determined the presence of the lectin gene (lec gene) in A. baumannii by using PCR technique, and lec PCR products were identified with various source of isolation and sequenced to screening for epidemiology and submitted to the gene bank NCBI under accession number (KX766405.1 and KX766406.1). Highlights: A. baumannii has an ability to produce lectin protein; Lec gene was detected in A. baumannii, and the sequence was recorded under accession number KX766405.1 and KX766406.1.; Lectin was extracted by glass beads and purified by chromatographyic technique; Lectin had strong effect against biofilm formation.
MeSH term(s)	Acinetobacter Infections/microbiology ; Acinetobacter baumannii/chemistry ; Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/genetics ; Acinetobacter baumannii/physiology ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/metabolism ; Anti-Bacterial Agents/pharmacology ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Bacterial Proteins/pharmacology ; Biofilms/drug effects ; Genes, Bacterial ; Genotype ; Humans ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/physiology ; Lectins/chemistry ; Lectins/genetics ; Lectins/pharmacology
Chemical Substances	Anti-Bacterial Agents ; Bacterial Proteins ; Lectins
Language	English
Publishing date	2018-04-04
Publishing country	England
Document type	Journal Article
ZDB-ID	1103149-9
ISSN	1944-7922 ; 1060-3271
ISSN (online)	1944-7922
ISSN	1060-3271
DOI	10.5740/jaoacint.17-0422
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Article: Geochemistry of Chilean Rivers Within the Central Zone: Distinguishing the Impact of Mining, Lithology and Physical Weathering

Viers, J / Auda, Y / Carretier, S / Chabaux, F / Herail, G / Pokrovsky, O. S / Regard, V / Seyler, P / Tolorza, V

Aquatic geochemistry. 2019 Apr., v. 25, no. 1-2

2019

Abstract: Several rivers of Chile from the latitude 30°–38° have been sampled during a stable anticyclonic period (October 2008). Firstly, our aim was to evaluate the dissolved chemical composition (major and trace elements) of poorly known central Chilean rivers. ...

Abstract	Several rivers of Chile from the latitude 30°–38° have been sampled during a stable anticyclonic period (October 2008). Firstly, our aim was to evaluate the dissolved chemical composition (major and trace elements) of poorly known central Chilean rivers. Secondly, we used a co-inertia analysis (see Dolédec and Chessel in Freshw Biol 31:277–294, 1994) to explore the possible relationships between the concentrations of elements and the environmental parameters [surface of the basin (km2)/mining activity (%)/average height (m)/watershed mean slope (%)/% of the surface covered by vegetation, sedimentary rocks, volcano-sedimentary rocks, volcanic rocks, granitoid rocks/erosion rate (mm/year)]. Globally, the major elements concentration could be explained by a strong control of mixed silicate and carbonate and evaporate lithology. The statistical treatment reveals that the highest metal and metalloids loads of Tinguiririca, Cachapoal, Aconcagua, Choapa, Illapel and Limari could be explained by the contribution of the mining activities in the uppermost part of these watersheds and/or by the higher geochemical background. Indeed, it remains difficult to decipher between a real mining impact and a higher geochemical background. Even if these rivers could be impacted by AMD process, the size of these watersheds is capable of diluting AMD waters by the alkaline character of tributaries that induce acid neutralization and decrease the level of metals and metalloids.
Keywords	basins ; carbonates ; chemical composition ; environmental factors ; geochemistry ; latitude ; metalloids ; metals ; mining ; neutralization ; rivers ; sedimentary rocks ; silicates ; trace elements ; vegetation ; volcanic rocks ; watersheds ; weathering ; Chile
Language	English
Dates of publication	2019-04
Size	p. 27-48.
Publishing place	Springer Netherlands
Document type	Article
ZDB-ID	1478538-9
ISSN	1573-1421 ; 1380-6165
ISSN (online)	1573-1421
ISSN	1380-6165
DOI	10.1007/s10498-019-09350-1
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Article: Comparative pharmacokinetics and pharmacodynamics of furosemide in Middle Eastern and in Asian subjects.

Abou-Auda, H S

International journal of clinical pharmacology and therapeutics

1998 Volume 36, Issue 5, Page(s) 275–281

Abstract: ... significant differences (p > 0.05) between the 2 ethnic groups in either the area under the plasma ... significantly higher (p < 0.05) in Middle Eastern subjects (2.9+/-0.7 h) than in Asian subjects (2.2+/-0.6 h ... while the maximal plasma concentration (Cmax) in Asian subjects (1,087+/-262 ng/ml) was significantly higher (p < 0 ...

Abstract	The pharmacokinetics and pharmacodynamics of a single oral dose of 40 mg furosemide has been compared in 11 healthy Middle Eastern Arabs with 12 Asian subjects under fasting conditions. There were no significant differences (p > 0.05) between the 2 ethnic groups in either the area under the plasma concentration time curve (AUC) or the time to maximal plasma concentration (tmax). The elimination half-life was significantly higher (p < 0.05) in Middle Eastern subjects (2.9+/-0.7 h) than in Asian subjects (2.2+/-0.6 h), while the maximal plasma concentration (Cmax) in Asian subjects (1,087+/-262 ng/ml) was significantly higher (p < 0.05) compared with Middle Eastern Arabs (776+/-163 ng/ml). The mean residence time (MRT) and the operative apparent volume of distribution (Vd/F) were significantly greater in Middle Eastern Arabs (4.5+/-0.9 h and 54.1+/-14.91) than in Asian subjects (3.6+/-0.8 h and 38.6+/-16.51). The difference between them in (Vd/F) abolished (p > 0.05) when corrected for body weight. The mean cumulative urinary excretion of furosemide in 8 h was 5.6 mg (range 1.6-15.2 mg) for Arabs and 6.1 mg (range 2.1-15.9 mg) for Asians. The relationships between furosemide-induced diuresis and furosemide, sodium, potassium, calcium, magnesium and chloride excretion rates appeared as a clockwise hysteresis loop indicating the development of tolerance during the course of drug action in both ethnic groups. No statistically significant differences (p > 0.05) were observed in the cumulative amounts excreted in urine of these electrolytes or their excretion rates between Arabs and Asians. The relationships between urinary excretion rates of sodium, potassium, calcium, magnesium, and chloride were linear with almost identical slopes for Arabs and Asians in each relationship.
MeSH term(s)	Adult ; Arabs ; Area Under Curve ; Asia, Southeastern/ethnology ; Diuretics/pharmacokinetics ; Diuretics/pharmacology ; Electrolytes/urine ; Fasting/blood ; Fasting/urine ; Female ; Furosemide/pharmacokinetics ; Furosemide/pharmacology ; Humans ; Male ; Middle Aged ; Saudi Arabia ; Spectrophotometry, Atomic
Chemical Substances	Diuretics ; Electrolytes ; Furosemide (7LXU5N7ZO5)
Language	English
Publishing date	1998-05
Publishing country	Germany
Document type	Clinical Trial ; Comparative Study ; Controlled Clinical Trial ; Journal Article
ZDB-ID	124384-6
ISSN	0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
ISSN	0946-1965 ; 0340-0026 ; 0300-9718 ; 0174-4879
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