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  1. Article ; Online: Bronchoscopy for diagnosis of ventilator-associated pneumonia.

    Martin-Loeches, Ignacio / Chastre, Jean / Wunderink, Richard G

    Intensive care medicine

    2022  Volume 49, Issue 1, Page(s) 79–82

    MeSH term(s) Humans ; Pneumonia, Ventilator-Associated/diagnosis ; Pneumonia, Ventilator-Associated/drug therapy ; Bronchoscopy ; Bronchoalveolar Lavage Fluid ; Anti-Bacterial Agents/therapeutic use ; Pneumonia/drug therapy ; Respiration, Artificial ; Cross Infection/diagnosis
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-09-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06898-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1089: Show issues Location:
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  2. Article ; Online: Ventilator-associated pneumonia and ventilator-associated conditions: apples are not oranges (mix only in a salade de fruits!).

    Chastre, Jean

    Critical care medicine

    2015  Volume 43, Issue 1, Page(s) 227–229

    MeSH term(s) Female ; Humans ; Male ; Pneumonia, Ventilator-Associated/prevention & control ; Respiration, Artificial/adverse effects ; Suction/methods
    Language English
    Publishing date 2015-01
    Publishing country United States
    Document type Comment ; Editorial
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000000758
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1261: Show issues Location:
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  3. Article ; Online: Viral Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia.

    Luyt, Charles-Edouard / Hékimian, Guillaume / Bréchot, Nicolas / Chastre, Jean

    Seminars in respiratory and critical care medicine

    2022  Volume 43, Issue 2, Page(s) 310–318

    Abstract: Among the viruses possibly responsible for hospital-acquired and ventilator-associated pneumonia, herpes simplex virus (HSV) is probably the most often involved: HSV reactivation is frequent in intensive care unit patients, and lung parenchymal infection ...

    Abstract Among the viruses possibly responsible for hospital-acquired and ventilator-associated pneumonia, herpes simplex virus (HSV) is probably the most often involved: HSV reactivation is frequent in intensive care unit patients, and lung parenchymal infection (HSV bronchopneumonitis) has been well described, either using cytological signs of parenchymal involvement in cells obtained during bronchoalveolar lavage or using HSV virus load in the lower respiratory tract. Although treating patients with HSV bronchopneumonitis may be recommended, based on expert opinion, prophylactic or preemptive treatment of HSV reactivation should be avoided. Ventilator-associated pneumonia due to cytomegalovirus (CMV) is less frequent than HSV bronchopneumonitis, and more difficult to diagnose. No data exists on the impact of antiviral treatment on CMV pneumonia. The involvement of respiratory viruses has been described in patients with healthcare-associated pneumonia and hospital-acquired pneumonia, but their role in ventilator-associated pneumonia is not clear.
    MeSH term(s) Cytomegalovirus Infections ; Herpes Simplex/diagnosis ; Herpesviridae Infections ; Hospitals ; Humans ; Pneumonia, Ventilator-Associated/drug therapy ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/therapy ; Simplexvirus
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0041-1740981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: The INHALE trial: multiple reasons for a negative result - Authors' reply.

    Niederman, Michael S / Chastre, Jean / Corkery, Kevin

    The Lancet. Infectious diseases

    2020  Volume 20, Issue 7, Page(s) 779–780

    MeSH term(s) Amikacin ; Anti-Bacterial Agents ; Double-Blind Method ; Humans ; Negative Results ; Respiration, Artificial
    Chemical Substances Anti-Bacterial Agents ; Amikacin (84319SGC3C)
    Language English
    Publishing date 2020-06-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30450-3
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    Zs.A 5743: Show issues Location:
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  5. Article: Eurocode Shear Design of Coarse Recycled Aggregate Concrete: Reliability Analysis and Partial Factor Calibration.

    Pacheco, João / de Brito, Jorge / Chastre, Carlos / Evangelista, Luís

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 15

    Abstract: This paper contributes to the definition of design clauses for coarse recycled aggregate concrete. One of the main reasons for scepticism towards recycled aggregate concrete is the perceived notion that the heterogeneity of recycled aggregates may ... ...

    Abstract This paper contributes to the definition of design clauses for coarse recycled aggregate concrete. One of the main reasons for scepticism towards recycled aggregate concrete is the perceived notion that the heterogeneity of recycled aggregates may increase the uncertainty of the behaviour of concrete. Therefore, the paper uses structural reliability concepts to propose partial factors for recycled aggregate concrete's design for shear failure. The paper builds upon a previous publication by the authors, in which the model uncertainty of recycled aggregate concrete elements designed for shear, with and without shear reinforcement, was compared with that of natural aggregate concrete elements. In that paper, the statistics of the model uncertainty for recycled aggregate concrete shear design were indeed found to be less favourable than those of natural aggregate concrete. Therefore, a partial factor for recycled aggregate concrete design is needed to ensure safety. This paper presents partial factors calibrated with explicit reliability analyses for different cases of design concerning beams (in the case of shear design of elements with shear reinforcement) and slabs (for the design of elements without shear reinforcement). For full incorporation of coarse recycled concrete aggregates and the design of elements without shear reinforcement, the calibrated partial factor reduces the design value of shear resistance by 10% (design with EN1992) or 15% (design with prEN1992) in comparison to natural aggregate concrete's design. For the shear design of elements with shear reinforcement, the partial factor decreases resistance by 5% but a sensitivity analysis showed that the reduction might be, under pessimistic expectations, of up to 20%.
    Language English
    Publishing date 2021-07-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14154081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book: Pneumopathie nosocomiale et ventilation artificiellle

    Augustí, C. / Chastre, Jean

    (Collection d'anesthésiologie et réanimation ; 47)

    1995  

    Author's details sous la dir. de J. Chastre ... Avec la collab. de C. Augustí
    Series title Collection d'anesthésiologie et réanimation ; 47
    Collection
    Keywords Respiration, Artificial / adverse effects ; Pneumonia / etiology ; Cross Infection / etiology
    Language French
    Size X, 166 S. : Ill.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book
    HBZ-ID HT007458348
    ISBN 2-225-84882-3 ; 978-2-225-84882-7
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1997 A 2243 order for loan Magazin

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  7. Article ; Online: Controversies and Evolving Concepts in Hospital-Acquired Pneumonia.

    Chastre, Jean / Luyt, Charles-Edouard

    Seminars in respiratory and critical care medicine

    2017  Volume 38, Issue 3, Page(s) 235–236

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Cross Infection/drug therapy ; Cross Infection/epidemiology ; Dose-Response Relationship, Drug ; Drug Monitoring ; Drug Resistance, Multiple, Bacterial ; Humans ; Intensive Care Units ; Pneumonia/drug therapy ; Pneumonia/epidemiology ; Pneumonia, Ventilator-Associated/drug therapy ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/prevention & control
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2017-06-04
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0037-1602850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Evolving problems with resistant pathogens.

    Chastre, J

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

    2008  Volume 14 Suppl 3, Page(s) 3–14

    Abstract: Over the past decade, patterns of resistance to antimicrobial agents have changed dramatically, particularly because of the increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA), as well as the increasing rate of antimicrobial ... ...

    Abstract Over the past decade, patterns of resistance to antimicrobial agents have changed dramatically, particularly because of the increasing prevalence of methicillin-resistant Staphylococcus aureus (MRSA), as well as the increasing rate of antimicrobial resistance seen in several species of Gram-negative bacteria. The unique nature of the intensive care unit (ICU) environment makes it a focus for the emergence and spread of many antimicrobial-resistant pathogens. The patients in this setting are commonly exposed to broad-spectrum antimicrobial agents, and opportunities for the cross-transmission of resistant bacteria from patient to patient abound. Not surprisingly, resistance rates have increased for most pathogens associated with nosocomial infections among ICU patients, and rates are almost universally higher among ICU patients than among non-ICU patients. MRSA strains are now spreading in the community, possibly because of antibiotic pressure outside the hospital, but also because of transfer from hospital settings. Such strains are worrisome, particularly the strains carrying the gene for Panton-Valentine leukocidin (PVL), which has been associated with heightened virulence. Managing infections caused by today's pathogens requires avoidance of antimicrobial agent overuse and appropriate selection, dosing and duration of efficacious antimicrobial therapy.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Drug Resistance, Bacterial ; Europe/epidemiology ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacterial Infections/epidemiology ; Gram-Negative Bacterial Infections/microbiology ; Humans ; Intensive Care Units ; Methicillin Resistance ; Microbial Sensitivity Tests ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/microbiology ; Staphylococcal Infections/epidemiology ; Staphylococcal Infections/microbiology ; Staphylococcus aureus/drug effects ; United States/epidemiology
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2008-04
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1328418-6
    ISSN 1469-0691 ; 1198-743X ; 1470-9465
    ISSN (online) 1469-0691
    ISSN 1198-743X ; 1470-9465
    DOI 10.1111/j.1469-0691.2008.01958.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4541: Show issues Location:
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    Zs.MO 284: Show issues

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  9. Article ; Online: Serious Infections in the ICU: Evolving Concepts in Management and Prevention.

    Chastre, Jean / Luyt, Charles-Edouard / Wolff, Michel

    Seminars in respiratory and critical care medicine

    2019  Volume 40, Issue 4, Page(s) 417–418

    MeSH term(s) Cross Infection/etiology ; Cross Infection/prevention & control ; Humans ; Infection Control/methods ; Intensive Care Units
    Language English
    Publishing date 2019-10-04
    Publishing country United States
    Document type Introductory Journal Article
    ZDB-ID 1183617-9
    ISSN 1098-9048 ; 1069-3424
    ISSN (online) 1098-9048
    ISSN 1069-3424
    DOI 10.1055/s-0039-1696663
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Œdème aigu pulmonaire réfractaire sous ECMO : une place pour l’atrioseptotomie de Rashkind ?

    Pham, V / Schmidt, M / Chastre, T / Combes, A / Waintraub, X / Chommeloux, J

    Annales de cardiologie et d'angeiologie

    2021  Volume 70, Issue 5, Page(s) 355–359

    Abstract: Hydrostatic pulmonary edema is a well-known complication of veinoarterial extracorporeal membrane oxygenation (VA-ECMO) caused by increased left ventricle afterload due to reverse blood flow in the aorta. Several techniques are commonly used for left ... ...

    Title translation Refractory pulmonary edema under ECMO: Is there a place for Rashkind atrioseptotomy?
    Abstract Hydrostatic pulmonary edema is a well-known complication of veinoarterial extracorporeal membrane oxygenation (VA-ECMO) caused by increased left ventricle afterload due to reverse blood flow in the aorta. Several techniques are commonly used for left ventricle venting such as intra-aortic balloon pump, Impella® (Abiomed, Danvers, MA), central surgical cannulation or Rahskind atrial septostomy. We reported two cases of hydrostatic pulmonary edema in patients under VA-ECMO for whom it was decided to perform Rashkind technique. The first is a late anterior myocardial infarction complicated with cardiac arrest and cardiogenic shock. Refractory hypoxemia due to hydrostatic pulmonary edema conducted us to perform atrial septostomy. The second case is a refractory cardiogenic shock due to left main stent thrombosis myocardial infarction. Procedural transesophageal echocardiography revealed a large left atrial thrombus extended to pulmonary veins preventing the procedure. These two cases illustrate the importance and gravity of pulmonary edema induced by VA-ECMO. The first shows that this technique is feasible, allows great left ventricle unloading and improves hypoxemia. The second underlines the interest of performing transesophageal echocardiography to look for pulmonary veins thrombosis that can take part in the elevation of hydrostatic pressure and forbid Rashkind manoeuver.
    MeSH term(s) Extracorporeal Membrane Oxygenation ; Heart Arrest ; Heart-Assist Devices ; Humans ; Pulmonary Edema/etiology ; Pulmonary Edema/therapy ; Shock, Cardiogenic
    Language French
    Publishing date 2021-05-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 418425-7
    ISSN 1768-3181 ; 0003-3928
    ISSN (online) 1768-3181
    ISSN 0003-3928
    DOI 10.1016/j.ancard.2021.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 216: Show issues

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