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  1. Article ; Online: Editorial commentary: Clarifying the association between atrial fibrillation and coronary artery disease.

    Dixit, Sanjay

    Trends in cardiovascular medicine

    2022  Volume 34, Issue 2, Page(s) 99–100

    MeSH term(s) Humans ; Coronary Artery Disease/diagnosis ; Coronary Artery Disease/epidemiology ; Coronary Artery Disease/therapy ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/therapy ; Coronary Artery Bypass ; Risk Factors
    Language English
    Publishing date 2022-11-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2022.11.002
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3419: Show issues Location:
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  2. Article ; Online: Navigating the risk of atrial fibrillation after successful ablation of lone typical atrial flutter.

    Dixit, Sanjay / Raad, Mohamad

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2024  Volume 26, Issue 2

    MeSH term(s) Humans ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/epidemiology ; Atrial Fibrillation/surgery ; Atrial Flutter/diagnosis ; Atrial Flutter/surgery ; Atrial Flutter/drug therapy ; Anti-Arrhythmia Agents/therapeutic use ; Catheter Ablation/adverse effects ; Treatment Outcome
    Chemical Substances Anti-Arrhythmia Agents
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euad343
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    Zs.A 5434: Show issues Location:
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  3. Article ; Online: Feasibility of Same Day Discharge in Atrial Fibrillation Patients Undergoing Catheter Ablation.

    Dixit, Sanjay

    JACC. Clinical electrophysiology

    2020  Volume 6, Issue 6, Page(s) 620–622

    MeSH term(s) Atrial Fibrillation/surgery ; Catheter Ablation ; Feasibility Studies ; Humans ; Patient Discharge ; Pulmonary Veins/surgery
    Language English
    Publishing date 2020-06-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2020.03.008
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  4. Article ; Online: Left Atrial Posterior Wall Isolation Guided by Local Electrogram Characteristics: Novel Innovation or Red Herring?

    Pothineni, Naga Venkata K / Dixit, Sanjay

    JACC. Clinical electrophysiology

    2023  Volume 9, Issue 12, Page(s) 2547–2549

    MeSH term(s) Humans ; Heart Atria/surgery ; Atrial Fibrillation/surgery
    Language English
    Publishing date 2023-11-22
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2023.09.027
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  5. Article ; Online: Atrial Fibrillation Management With Antiarrhythmic Drug Therapy: Balancing Benefits and Bradycardia Risks.

    Dixit, Sanjay / Oranefo, Justice U / Raad, Mohamad

    Journal of the American College of Cardiology

    2024  Volume 83, Issue 11, Page(s) 1039–1041

    MeSH term(s) Humans ; Anti-Arrhythmia Agents/adverse effects ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Bradycardia/chemically induced ; Catheter Ablation
    Chemical Substances Anti-Arrhythmia Agents
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2024.01.015
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1846: Show issues Location:
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    Zs.MO 196: Show issues

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  6. Article ; Online: Automated Synthesis of [11C]PiB via [11CH3OTf]-as Methylating Agent for PET Imaging of β-Amyloid.

    Singh, Akhilesh K / Gambhir, Sanjay / Dixit, Manish

    Current radiopharmaceuticals

    2024  

    Abstract: Aim: Efficient synthesis of precursor from commercially available starting materials and automated radiosynthesis of [11C]PiB using commercially available dedicated [11C]- Chemistry module from the synthesized precursor.: Background: [11C]PiB is a ... ...

    Abstract Aim: Efficient synthesis of precursor from commercially available starting materials and automated radiosynthesis of [11C]PiB using commercially available dedicated [11C]- Chemistry module from the synthesized precursor.
    Background: [11C]PiB is a promising radiotracer for PET imaging of β-Amyloid, advancing Alzheimer's disease research. The availability of precursors and protocols for efficient radiolabelling foster the applications of any radiotracer. Efficient synthesis of PiB precursor was performed using anisidine and 4-nitrobenzoyl chloride as starting materials in 5 steps, having addition, substitutions, and cyclization chemical methodologies. This precursor was used for fully automated radiosynthesis of [11C]PiB in a commercially available synthesizer, MPS-100 (SHI, Japan). The synthesized [11C]PiB was purified via solid-phase methodology, and its quality control was by the quality and safety criteria required for clinical use.
    Methods: The synthesis of desired precursors and standard authentic compounds started with commercially available materials with 70-80% yields. The standard analytical methods characterized all synthesized compounds. The fully automated [11C]-chemistry synthesizer (MPS-100) used for radiosynthesis of [11C]PiB with [11C]CH3OTf acts as a methylating agent. For radiolabelling, varied amounts of precursor and time of reaction were explored. The resulting crude product underwent purification through solid-phase cartridges. The synthesized radiotracer was analyzed using analytical tools such as radio TLC, HPLC, pH endo-toxicity, and half-life.
    Results: The precursor for radiosynthesis of [11C]PiB was achieved in excellent yield using simple and feasible chemistry. A protocol for radiolabelling of precursor to synthesized [11C]PiB was developed using an automated synthesizer. The crude radiotracer was purified by solid-phase cartridge, with a decay-corrected radiochemical yield of 40±5% and radiochemical purity of more than 97% in approx 20 minutes (EOB). The specific activity was calculated and found in a 110-121 mCi/μmol range.
    Conclusion: A reliable methodology was developed for preparing precursor followed by fully automated radiolabeling using [11C]MeOTf as a methylating agent to synthesize [11C]PiB. The final HPLC-free purification yielded more than 97% radiochemical purity tracer within one radionuclide half-life. The method was reproducible and efficient for any clinical center.
    Language English
    Publishing date 2024-03-06
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1874-4729
    ISSN (online) 1874-4729
    DOI 10.2174/0118744710295705240229114137
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  7. Article ; Online: Utility of Multipolar Catheter for Characterizing Myocardial Substrate in a Porcine Post Myocardial Infarction Model.

    Dixit, Sanjay / Dhakal, Bishnu P

    JACC. Clinical electrophysiology

    2022  Volume 8, Issue 4, Page(s) 450–452

    MeSH term(s) Animals ; Catheters ; Humans ; Myocardial Infarction ; Swine ; Tachycardia, Ventricular
    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2846739-5
    ISSN 2405-5018 ; 2405-500X ; 2405-500X
    ISSN (online) 2405-5018 ; 2405-500X
    ISSN 2405-500X
    DOI 10.1016/j.jacep.2022.01.006
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  8. Article ; Online: Assessing snow cover patterns in the Indus-Ganga-Brahmaputra River Basins of the Hindu Kush Himalayas using snow persistence and snow line as metrics

    Abhilasha Dixit / Ajanta Goswami / Sanjay Jain / Pritam Das

    Environmental Challenges, Vol 14, Iss , Pp 100834- (2024)

    2024  

    Abstract: This study investigates the utilization of snow persistence (SP) as a metric to assess snow cover patterns in the Upper Indus-Ganga-Brahmaputra (UIGB) river basins, an area notably susceptible to climate change. The objectives of the study are to ... ...

    Abstract This study investigates the utilization of snow persistence (SP) as a metric to assess snow cover patterns in the Upper Indus-Ganga-Brahmaputra (UIGB) river basins, an area notably susceptible to climate change. The objectives of the study are to establish seasonal snow persistence, calculate seasonal snow lines, and quantify the temporal trend of snow lines. It also underscores the importance of accounting for climate zones, elevation, and seasonal variations when investigating snow persistence. Furthermore, the study estimates the snow line elevation using the Regional Snow Line Elevation (RSLE) approach with remote sensing data. Over a span of 19 years (2003–2021), the analysis of SP% in UIGB basins indicates a notable reduction in the mean annual permanent snow zone area, decreasing by -2.61 %, -2.37 %, and -4.18 % from winter (DJF) to summer (JJA). The results uncover considerable fluctuations in snow cover across various climate zones and seasons. The impact of warming is clearly visible on snow cover, instigating a transition from permanent and seasonal snow zones towards intermittent and minimal or no snow zones. The seasonal analysis of the snow line from 2003 to 2021 illustrates fluctuation in the snow line for UIGB basins, from 2349 ± 117 m to 4802 ± 51.7 m, 3003 ± 286 m to 4871 ± 64.4 m, and 3238 ± 127 m to 5047 ± 73 m between winter and summer seasons, with the most significant fluctuation occurring in the Brahmaputra basin. A substantial increase in Snow Line Elevation (SLE) is observed for Ganga (6.67 m yr−1), and Brahmaputra (7.26 m yr−1) at the conclusion of the melting season. These findings offer invaluable insights for formulating targeted mitigation strategies in the snow accumulation regions of each river basin. They equip us with the ability to respond effectively to the spatiotemporal variability of snow cover caused by climate change.
    Keywords Upper Indus-Ganga-Brahmaputra (UIGB) ; Regional Snow Line Elevation (RSLE) ; Snow Persistence (SP) ; Koppen Climate Classification ; Remote Sensing ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Insight into Tumor Hypoxia: Radionuclide-based Biomarker as Diagnostic Tools.

    Saxena, Priya / Gambhir, Sanjay / Dixit, Manish

    Current topics in medicinal chemistry

    2023  Volume 23, Issue 12, Page(s) 1136–1154

    Abstract: The radiolabeled tracers have been extensively utilized to access various physiological and pathological conditions non-invasively, such as cancers, inflammation, and organ-specific imaging. These tracers demonstrate and study tumor hypoxia in several ... ...

    Abstract The radiolabeled tracers have been extensively utilized to access various physiological and pathological conditions non-invasively, such as cancers, inflammation, and organ-specific imaging. These tracers demonstrate and study tumor hypoxia in several malignancies. Hypoxia is commonly seen in solid tumors. Tumor Hypoxia is a non-physiological condition of reduced oxygen concentration in the tumor. Hypoxia is associated with adverse outcomes such as treatment resistance and metastases in solid tumors. Tumor hypoxia may result in resistance to radiation therapy and chemotherapy, leading to a poor prognosis. It is one of the clinically paramount factors in treatment planning. Various chemical scaffolds are labeled with compatible radioisotopes for imaging hypoxia by Single-photon emission computed tomography (SPECT) and Positron emission tomography (PET). Radionuclides, such as [
    MeSH term(s) Humans ; Tumor Hypoxia ; Radiopharmaceuticals/chemistry ; Copper ; Cell Hypoxia ; Positron-Emission Tomography/methods ; Neoplasms/diagnostic imaging ; Neoplasms/metabolism ; Radioisotopes ; Hypoxia/diagnosis ; Biomarkers/metabolism
    Chemical Substances Radiopharmaceuticals ; Copper (789U1901C5) ; Radioisotopes ; Biomarkers
    Language English
    Publishing date 2023-04-17
    Publishing country United Arab Emirates
    Document type Review ; Journal Article
    ZDB-ID 2064823-6
    ISSN 1873-4294 ; 1568-0266
    ISSN (online) 1873-4294
    ISSN 1568-0266
    DOI 10.2174/1568026623666230515154442
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5572: Show issues Location:
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  10. Article: Mapping and ablating ventricular arrhythmias within the coronary venous system.

    Dixit, Sanjay / Lin, Aung

    Indian pacing and electrophysiology journal

    2020  Volume 20, Issue 4, Page(s) 164–165

    Language English
    Publishing date 2020-06-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2123606-9
    ISSN 0972-6292
    ISSN 0972-6292
    DOI 10.1016/j.ipej.2020.06.004
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