LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 48

Search options

  1. Article ; Online: On Practice Guidelines for the Management of Anal Fissures.

    Damin, Daniel C / Contu, Paulo C

    Diseases of the colon and rectum

    2023  Volume 66, Issue 10, Page(s) e1056

    MeSH term(s) Humans ; Fissure in Ano/diagnosis ; Fissure in Ano/therapy ; Nitroglycerin ; Anal Canal/surgery ; Chronic Disease
    Chemical Substances Nitroglycerin (G59M7S0WS3)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000003003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: The role of colonoscopy in young patients with rectal bleeding: a systematic review and meta-analysis.

    Colles, Tuane / Ziegelmann, Patrícia K / Damin, Daniel C

    International journal of colorectal disease

    2023  Volume 38, Issue 1, Page(s) 230

    Abstract: Purpose: Anal bleeding is a frequent complaint in the coloproctological practice. Although usually associated with common anorectal disorders, it may represent a sign of an occult colorectal carcinoma. Our purpose was to evaluate the accuracy of the ... ...

    Abstract Purpose: Anal bleeding is a frequent complaint in the coloproctological practice. Although usually associated with common anorectal disorders, it may represent a sign of an occult colorectal carcinoma. Our purpose was to evaluate the accuracy of the colonoscopy for detection of neoplastic lesions in patients under 50 years of age with rectal bleeding.
    Methods: This systematic review and meta-analysis searched publications in PubMed, Web of Science, and Cochrane Library databases up to August, 2023. Cross-sectional and case-control studies including patients under 50 years with rectal bleeding evaluated by colonoscopy were included. Primary outcome was prevalence of neoplastic lesions (adenomas and adenocarcinomas). Secondary outcomes were prevalence of those lesions according to age and anatomic location. The study was registered on PROSPERO (CRD42021257859) on July 5, 2021.
    Results: Nine studies comprising 4162 patients were analyzed. A total of 398 patients with adenomas and 40 patients with adenocarcinoma were identified. Prevalence of neoplastic lesions (adenomas and carcinomas) was 10%. In patients under 40 years, the prevalence of neoplastic lesions was 7% (6% of adenomas, 1% of carcinomas). Among patients aged 40-50 years the prevalence was 15%, 14%, and 1%, respectively. Most lesions (71%) were located distally to splenic flexure.
    Conclusion: About 10% of patients under 50 years with anal bleeding will have a neoplastic lesion detected through colonoscopy. The greatest benefit of the procedure is observed between 40 and 50 years. Almost 30% of the neoplastic lesions were found in the proximal colon and could not be detected without the performance of a complete colonoscopy.
    MeSH term(s) Humans ; Middle Aged ; Cross-Sectional Studies ; Colonoscopy ; Colon ; Gastrointestinal Hemorrhage/diagnosis ; Gastrointestinal Hemorrhage/etiology ; Adenocarcinoma ; Carcinoma
    Language English
    Publishing date 2023-09-15
    Publishing country Germany
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 84975-3
    ISSN 1432-1262 ; 0179-1958
    ISSN (online) 1432-1262
    ISSN 0179-1958
    DOI 10.1007/s00384-023-04524-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Predictors for anastomotic leak after colon and rectal resection.

    Damin, Daniel C / Damin, Andrea P

    Annals of surgery

    2015  Volume 261, Issue 4, Page(s) e94

    MeSH term(s) Anastomotic Leak/etiology ; Colectomy ; Female ; Humans ; Male ; Rectum/surgery
    Language English
    Publishing date 2015-04
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000000230
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: The role of Hartmann's procedure in the elective management of rectal cancer: results of a Brazilian cohort study.

    Lazzaron, Anderson Rech / Silveira, Ingrid / Machado, Pauline Simas / Damin, Daniel C

    Revista do Colegio Brasileiro de Cirurgioes

    2021  Volume 48, Page(s) e20212977

    Abstract: Background: although preservation of bowel continuity is a major goal in rectal cancer surgery, a colorectal anastomosis may be considered an unacceptably high-risk procedure, particularly for patients with multiple comorbidities. We aimed to assess ... ...

    Abstract Background: although preservation of bowel continuity is a major goal in rectal cancer surgery, a colorectal anastomosis may be considered an unacceptably high-risk procedure, particularly for patients with multiple comorbidities. We aimed to assess rates of surgical complications in rectal cancer patients according to the type of procedure they had undergone.
    Materials and methods: this cohort included all rectal cancer patients undergoing elective resection at a referral academic hospital over 16 years. There were three study groups according to the type of performed operation: (1) rectal resection with anastomosis without defunctioning stoma (DS); (2) rectal resection with anastomosis and DS; and (3) Hartmann's procedure (HP). Postoperative complications and clinical outcomes were assessed.
    Results: four-hundred and two patients were studied. The 118 patients in group 3 were significantly older (>10 years), had higher Charlson Comorbidity Index scores, and more ASA class ≥3 than patients in the other two groups. Sixty-seven patients (16.7%) had Clavien-Dindo complications grade ≥ III, corresponding to an incidence of 11.8%, 20.9%, and 14.4% in groups 1, 2, and 3, respectively (p=0.10). Twenty-nine patients (7.2%) had major septic complications that required reoperation, with an incidence of 10.8%, 8.2% and 2.5% in groups 1, 2 and 3, respectively (p=0.048). Twenty-one percent of the group 2 patients did not undergo the stoma closure after a 24-month follow-up.
    Conclusion: HP was associated with a lower incidence of reoperation due to intra-abdominal septic complications. This procedure remains an option for patients in whom serious surgical complications are anticipated.
    MeSH term(s) Anastomosis, Surgical ; Cohort Studies ; Colostomy ; Elective Surgical Procedures ; Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Rectal Neoplasms/surgery ; Rectum/surgery ; Reoperation ; Retrospective Studies ; Treatment Outcome
    Language Portuguese
    Publishing date 2021-08-09
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2223714-8
    ISSN 1809-4546 ; 1809-4546
    ISSN (online) 1809-4546
    ISSN 1809-4546
    DOI 10.1590/0100-6991e-20212977
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Prolene Hernia System Maximum Repair: A New Concept in Sports Hernia Surgery.

    Da Rosa, André M / Reusch, Marcus / Aguzzoli, Marcus / Fonseca, Mariana K / Damin, Daniel C

    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine

    2022  Volume 33, Issue 2, Page(s) 183–186

    Abstract: Objective: To describe and present the clinical results of a new surgical treatment for sports hernia.: Design: Retrospective cohort study.: Setting: Tertiary hospital.: Patients: Athletes who underwent sports hernia repair using the proposed ... ...

    Abstract Objective: To describe and present the clinical results of a new surgical treatment for sports hernia.
    Design: Retrospective cohort study.
    Setting: Tertiary hospital.
    Patients: Athletes who underwent sports hernia repair using the proposed technique between July 2006 and June 2020.
    Intervention: The surgery consists of a combination of a mini-open incision and preperitoneal placement of a three-dimensional bilayer permanent mesh (PHS).
    Main outcome measures: The main clinical outcomes of the procedure were reviewed, including incidence of complications, long-term results, and recurrence rate.
    Results: Ninety-two sports hernia repairs were performed on 87 patients (79 male and 8 female patients, median age 30.2 ± 7.8 years). No intraoperative complications were observed. The mean follow-up was 15 months. Seventy-seven patients (88.5%) successfully resumed preinjury physical activities within 8 weeks; 80 patients (91.9%) within 12 weeks; and 83 (95.4%) within 6 months (median time of 10 weeks). Only one patient reported recurrence of symptoms.
    Conclusion: Mini-open incision PHS repair seems to be a safe and effective method for treatment of sports hernia, resulting in early return to physical activities, with few complications, and low recurrence rate.
    MeSH term(s) Humans ; Male ; Female ; Young Adult ; Adult ; Treatment Outcome ; Herniorrhaphy/methods ; Polypropylenes ; Retrospective Studies ; Hernia, Inguinal/surgery ; Hernia, Inguinal/diagnosis ; Recurrence
    Chemical Substances Polypropylenes
    Language English
    Publishing date 2022-11-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1062530-6
    ISSN 1536-3724 ; 1050-642X
    ISSN (online) 1536-3724
    ISSN 1050-642X
    DOI 10.1097/JSM.0000000000001096
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: Splenic flexure mobilization in sigmoid and rectal cancer resections: a meta-analysis of surgical outcomes.

    Damin, Daniel C / Betanzo, Luize N / Ziegelmann, Patrícia K

    Revista do Colegio Brasileiro de Cirurgioes

    2019  Volume 46, Issue 4, Page(s) e20192171

    Abstract: Objective: to evaluate the influence of the splenic flexure mobilization for the main surgical outcomes of patients submitted to resection of sigmoid and rectal cancer.: Methods: we searched the MEDLINE, Cochrane Central Register of Controlled Trials ...

    Title translation Mobilização da flexura esplênica nas ressecções dos tumores de reto e sigmoide: meta-análise dos resultados cirúrgicos.
    Abstract Objective: to evaluate the influence of the splenic flexure mobilization for the main surgical outcomes of patients submitted to resection of sigmoid and rectal cancer.
    Methods: we searched the MEDLINE, Cochrane Central Register of Controlled Trials and LILACS, using the terms "splenic flexure mobilization", "colorectal surgery", "rectal cancer", "anterior resection", "sigmoid colon cancer", and "sigmoid resection". The main outcome was anastomotic dehiscence. Other outcomes analyzed were mortality, bleeding, infection and general complications. We estimated the effect sizes by grouping data from six case-control studies (1,433 patients) published until January 2018.
    Results: our meta-analysis showed that patients undergoing complete mobilization of the splenic flexure had a higher risk of anastomotic dehiscence (RR=2.27, 95%CI: 1.22-4.23) compared with those not submitted to this procedure. There was no difference between the groups in terms of mortality, bleeding, infection and general complications.
    Conclusion: splenic flexure mobilization is associated with a higher risk of anastomotic dehiscence in resections of sigmoid and rectal cancer. This surgical maneuver should be used with caution in the surgical management of sigmoid or rectal cancers.
    MeSH term(s) Colectomy/adverse effects ; Colectomy/methods ; Humans ; Postoperative Complications ; Proctectomy/adverse effects ; Proctectomy/methods ; Rectal Neoplasms/surgery ; Sigmoid Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2019-10-17
    Publishing country Brazil
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 2223714-8
    ISSN 1809-4546 ; 1809-4546
    ISSN (online) 1809-4546
    ISSN 1809-4546
    DOI 10.1590/0100-6991e-20192171
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: First colonoscopic management of a small-bowel obstruction secondary to intragastric balloon migration.

    Damin, Daniel C / Biazi, Bruna H / Colles, Tuane / Lazzaron, Anderson R / Tarta, Cláudio

    Gastrointestinal endoscopy

    2020  Volume 92, Issue 6, Page(s) 1265–1266

    MeSH term(s) Adult ; Colonoscopy/methods ; Female ; Gastric Balloon/adverse effects ; Humans ; Ileal Diseases/diagnostic imaging ; Ileal Diseases/etiology ; Ileal Diseases/surgery ; Intestinal Obstruction/diagnostic imaging ; Intestinal Obstruction/etiology ; Intestinal Obstruction/surgery ; Obesity, Morbid/surgery ; Prosthesis Failure/adverse effects ; Prosthesis Failure/etiology ; Prosthesis Implantation/adverse effects ; Prosthesis Implantation/instrumentation
    Language English
    Publishing date 2020-06-24
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2020.06.050
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Evolving treatment strategies for colorectal cancer: a critical review of current therapeutic options.

    Damin, Daniel C / Lazzaron, Anderson R

    World journal of gastroenterology

    2014  Volume 20, Issue 4, Page(s) 877–887

    Abstract: Management of rectal cancer has markedly evolved over the last two decades. New technologies of staging have allowed a more precise definition of tumor extension. Refinements in surgical concepts and techniques have resulted in higher rates of sphincter ... ...

    Abstract Management of rectal cancer has markedly evolved over the last two decades. New technologies of staging have allowed a more precise definition of tumor extension. Refinements in surgical concepts and techniques have resulted in higher rates of sphincter preservation and better functional outcome for patients with this malignancy. Although, preoperative chemoradiotherapy followed by total mesorectal excision has become the standard of care for locally advanced tumors, many controversial matters in management of rectal cancer still need to be defined. These include the feasibility of a non-surgical approach after a favorable response to neoadjuvant therapy, the ideal margins of surgical resection for sphincter preservation and the adequacy of minimally invasive techniques of tumor resection. In this article, after an extensive search in PubMed and Embase databases, we critically review the current strategies and the most debatable matters in treatment of rectal cancer.
    MeSH term(s) Chemoradiotherapy, Adjuvant ; Colectomy/adverse effects ; Colectomy/mortality ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/therapy ; Humans ; Neoadjuvant Therapy/adverse effects ; Neoadjuvant Therapy/mortality ; Neoplasm Staging ; Neoplasm, Residual ; Patient Selection ; Treatment Outcome
    Language English
    Publishing date 2014-01-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v20.i4.877
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Mammographic and Ultrasonographic Imaging Analysis for Neoadjuvant Chemotherapy Evaluation: Volume Reduction Indexes That Correlate With Pathological Complete Response.

    Mello, Juliana M / Sarvacinski, Flavia / Schaefer, Flavia C / Ercolani, Daniel S / Lobato, Nathalia R / Martins, Yasmine C / Zwetsch, Guilherme / Bittelbrunn, Fernando P / Ferreira, Charles F / Damin, Andrea P

    Cureus

    2022  Volume 14, Issue 10, Page(s) e29960

    Abstract: Introduction: We aimed to evaluate volume reduction in digital mammography (DM) and ultrasound (US) for neoadjuvant chemotherapy (NAC) evaluation, with breast cancer-specific survival and pathological complete response (pCR) associations.: Methods: ... ...

    Abstract Introduction: We aimed to evaluate volume reduction in digital mammography (DM) and ultrasound (US) for neoadjuvant chemotherapy (NAC) evaluation, with breast cancer-specific survival and pathological complete response (pCR) associations.
    Methods: This is a retrospective observational cohort study analyzing recorded images in 122 selected subjects out of which 569 patients presented with advanced breast cancers. Spearman's correlation and generalized estimating equations (GEE) compared volume reduction on DM and US between pCR and non-pCR after NAC with post-surgical anatomopathology. Cox regression and Kaplan-Meier curves analyzed associations between cancer-specific survival, pCR, and volume reductions.
    Results: A total of 34.4% (N=42) obtained pCR and 65.6% (N=80) did not. Minimum percentage indexes needed to correlate with pCR over time were, at least, 28.9% for DM (p=0.006) and 10.36% for US (p=0.046), with high specificity (US=98%, DM=93%) but low sensitivity (US=7%, DM=18%). Positive predictive values were 82% (DM) and 86% (US) and negative predictive values were 37% (DM) and 36% (US). Cox regression and Kaplan-Meier curves demonstrated associations of breast cancer-specific survival with pCR (Cox regression coefficient {B}=0.209, CI 95%=0.048-0.914, p=0.038).
    Conclusions: At least 28.9% of volume reduction on DM and 10.36% of volume reduction on US are correlated with pCR. Furthermore, pCR was associated with breast cancer-specific survival after NAC in volumetric morphological imaging analysis.
    Language English
    Publishing date 2022-10-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29960
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Young patients with benign anal diseases and rectal bleeding: should a colonoscopy be performed?

    Muller, Belisa G / Contu, Paulo C / Tarta, Cláudio / Lazzaron, Anderson R / Ghezzi, Tiago L / Damin, Daniel C

    International journal of colorectal disease

    2019  Volume 34, Issue 12, Page(s) 2069–2073

    Abstract: Background and aim: There is no consensus whether a colonoscopy should be recommended for patients under 50 years of age who present with both anal bleeding and benign anal diseases. The aim of this study is to evaluate the effectiveness of colonoscopy ... ...

    Abstract Background and aim: There is no consensus whether a colonoscopy should be recommended for patients under 50 years of age who present with both anal bleeding and benign anal diseases. The aim of this study is to evaluate the effectiveness of colonoscopy to detect neoplastic lesions in this specific group of patients.
    Methods: A prospective study analyzing the results of colonoscopies performed in patients younger than 50 years of age who reported a rectal bleeding and also had a diagnosis of benign anal disease at first clinical visit.
    Results: One hundred and eighty-seven consecutive patients were prospectively included in this study. In 35 patients (18.7%), adenomatous polyps were diagnosed. Thirty-seven percent of those lesions (13 cases) were further classified as either advanced adenomas or serrated adenomas. The prevalence of adenomas was 14.6% among patients under the age of 40 and 20% among those between 40 and 50 years of age. Thirty-one percent of the adenomas (11 cases) were located in the right colon, without any other concomitant lesion in the distal colon. In addition, an unsuspected case of sigmoid carcinoma was diagnosed.
    Conclusion: The performance of colonoscopy in young patients with benign anal diseases and hematochezia resulted in a high rate of detection of neoplastic lesions. The method might be considered as a valid strategy of investigation in this frequent clinical situation.
    MeSH term(s) Adenomatous Polyps/epidemiology ; Adenomatous Polyps/pathology ; Adult ; Age Factors ; Anus Diseases/epidemiology ; Anus Diseases/pathology ; Brazil/epidemiology ; Clinical Decision-Making ; Colonic Polyps/epidemiology ; Colonic Polyps/pathology ; Colonoscopy ; Colorectal Neoplasms/epidemiology ; Colorectal Neoplasms/pathology ; Female ; Gastrointestinal Hemorrhage/epidemiology ; Humans ; Male ; Middle Aged ; Patient Selection ; Predictive Value of Tests ; Prevalence ; Prospective Studies ; Risk Assessment ; Risk Factors
    Language English
    Publishing date 2019-11-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 84975-3
    ISSN 1432-1262 ; 0179-1958
    ISSN (online) 1432-1262
    ISSN 0179-1958
    DOI 10.1007/s00384-019-03425-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top