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  1. Article ; Online: Author Response: Prestroke Disability and Outcome After Thrombectomy for Emergent Anterior Circulation Large Vessel Occlusion Stroke.

    de Havenon, Adam

    Neurology

    2022  Volume 98, Issue 22, Page(s) 951

    MeSH term(s) Arterial Occlusive Diseases ; Humans ; Ischemic Stroke ; Stroke/surgery ; Thrombectomy
    Language English
    Publishing date 2022-05-27
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200728
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  2. Article ; Online: Remnants of Risk: Further Evidence for the Importance of Physiologic Variability.

    de Havenon, Adam / Roever, Leonardo

    Stroke

    2022  Volume 53, Issue 6, Page(s) 1942–1943

    MeSH term(s) Blood Pressure/physiology ; Humans ; Hypertension
    Language English
    Publishing date 2022-05-11
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.122.039365
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    Zs.A 448: Show issues Location:
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  3. Book ; Online ; E-Book: Carotid Artery Disease

    Park, Min S. / Kalani, M. Yashar S. / de Havenon, Adam / McNally, J. Scott

    Evaluation and Management

    2020  

    Abstract: This truly comprehensive title addresses all aspects of the evaluation and management of carotid artery disease. The extracranial carotid artery is an area of confluence for both medical and surgical specialists. Given its unique position and function in ...

    Author's details edited by Min S. Park, M. Yashar S. Kalani, Adam de Havenon, J. Scott McNally
    Abstract This truly comprehensive title addresses all aspects of the evaluation and management of carotid artery disease. The extracranial carotid artery is an area of confluence for both medical and surgical specialists. Given its unique position and function in the body, disease states that involve the carotid artery require a unique approach to ensure the best outcomes for patients. Developed by a multidisciplinary team of thought leaders from across medical, surgical, and radiological disciplines, Carotid Artery Disease: Evaluation and Management provides a diverse resource where readers can find presentation, evaluation, and management recommendations for any process involving the extracranial carotid artery, be it related to atherosclerotic, traumatic, inflammatory, or even oncologic disease. Indeed this title is a unique offering in that one can find traditional, and even exclusively medical, conditions within the same binding as surgical or interventional ones. Typically, access to this type of information requires the purchase of multiple different texts, but this complete title distills the evaluation and management of carotid artery disease into a one-of-a-kind, practical, accessible reference. A much-needed and invaluable contribution to the clinical literature, Carotid Artery Disease: Evaluation and Management will be of great interest to anyone early in his or her career and needing an introduction to the field, as well as seasoned clinicians in need of state-of-the-art, refresher information.
    Keywords Neurosurgery ; Neurology  ; Cardiology ; Otorhinolaryngology ; Neurology
    Subject code 616.13607543
    Language English
    Size 1 online resource (294 pages)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-41138-9 ; 3-030-41137-0 ; 978-3-030-41138-1 ; 978-3-030-41137-4
    DOI 10.1007/978-3-030-41138-1
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Past, Present, and Future of Intracranial Atherosclerosis Treatment.

    de Havenon, Adam / Turan, Tanya N

    Stroke

    2023  Volume 55, Issue 2, Page(s) 471–473

    MeSH term(s) Humans ; Stroke ; Brain Ischemia ; Intracranial Arteriosclerosis/diagnostic imaging ; Intracranial Arteriosclerosis/therapy ; Angioplasty ; Stents ; Treatment Outcome
    Language English
    Publishing date 2023-12-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80381-9
    ISSN 1524-4628 ; 0039-2499 ; 0749-7954
    ISSN (online) 1524-4628
    ISSN 0039-2499 ; 0749-7954
    DOI 10.1161/STROKEAHA.123.044270
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  5. Article ; Online: Secondary Ischemic Stroke Prevention.

    Bangad, Aaron / Abbasi, Mehdi / de Havenon, Adam

    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

    2023  Volume 20, Issue 3, Page(s) 721–731

    Abstract: The health burden of ischemic stroke is high and will continue to increase with an aging population. Recurrent ischemic stroke is increasingly recognized as a major public health concern with potentially debilitating sequelae. Thus, it is imperative to ... ...

    Abstract The health burden of ischemic stroke is high and will continue to increase with an aging population. Recurrent ischemic stroke is increasingly recognized as a major public health concern with potentially debilitating sequelae. Thus, it is imperative to develop and implement effective strategies for stroke prevention. When considering secondary ischemic stroke prevention, it is important to consider the mechanism of the first stroke and the related vascular risk factors. Secondary ischemic stroke prevention typically includes multiple medical and, potentially, surgical treatments, but with the shared goal of reducing the risk of recurrent ischemic stroke. Providers, health care systems, and insurers also need to consider the availability of treatments, their cost and patient burden, methods for improving adherence, and interventions that target lifestyle risk factors such as diet or activity. In this article, we discuss aspects from the 2021 AHA Guideline on Secondary Stroke Prevention as well as highlight additional information relevant to best practices for reducing recurrent stroke risk.
    MeSH term(s) Humans ; Aged ; Ischemic Stroke ; Stroke/epidemiology ; Stroke/etiology ; Stroke/prevention & control ; Risk Factors ; Secondary Prevention/methods ; Life Style
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2316693-9
    ISSN 1878-7479 ; 1933-7213
    ISSN (online) 1878-7479
    ISSN 1933-7213
    DOI 10.1007/s13311-023-01352-w
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  6. Article ; Online: Rates and reasons for hospital readmission after acute ischemic stroke in a US population-based cohort.

    Zhou, Lily W / Lansberg, Maarten G / de Havenon, Adam

    PloS one

    2023  Volume 18, Issue 8, Page(s) e0289640

    Abstract: Hospital readmissions following stroke are costly and lead to worsened patient outcomes. We examined readmissions rates, diagnoses at readmission, and risk factors associated with readmission following acute ischemic stroke (AIS) in a large United States ...

    Abstract Hospital readmissions following stroke are costly and lead to worsened patient outcomes. We examined readmissions rates, diagnoses at readmission, and risk factors associated with readmission following acute ischemic stroke (AIS) in a large United States (US) administrative database. Using the 2019 Nationwide Readmissions Database, we identified adults discharged with AIS (ICD-10-CM I63*) as the principal diagnosis. Survival analysis with Weibull accelerated failure time regression was used to examine variables associated with hospital readmission. In 2019, 273,811 of 285,451 AIS patients survived their initial hospitalization. Of these, 60,831 (22.2%) were readmitted within 2019. Based on Kaplan Meyer analysis, readmission rates were 9.7% within 30 days and 30.5% at 1 year following initial discharge. The most common causes of readmissions were stroke and post stroke sequalae (25.4% of 30-day readmissions, 15.0% of readmissions between 30-364 days), followed by sepsis (10.3% of 30-day readmissions, 9.4% of readmissions between 30-364 days), and acute renal failure (3.2% of 30-day readmissions, 3.0% of readmissions between 30-364 days). After adjusting for multiple patient and hospital-level characteristics, patients at increased risk of readmission were older (71.6 vs. 69.8 years, p<0.001) and had longer initial lengths of stay (7.6 vs. 6.2 day, p<0.001). They more often had modifiable comorbidities, including vascular risk factors (hypertension, diabetes, atrial fibrillation), depression, epilepsy, and drug abuse. Social determinants associated with increased readmission included living in an urban (vs. rural) setting, living in zip-codes with the lowest median income, and having Medicare insurance. All factors were significant at p<0.001. Unplanned hospital readmissions following AIS were high, with the most common reasons for readmission being recurrent stroke and post stroke sequalae, followed by sepsis and acute renal failure. These findings suggest that efforts to reduce readmissions should focus on optimizing secondary stroke and infection prevention, particularly among older socially disadvantaged patients.
    MeSH term(s) Adult ; Humans ; Aged ; United States/epidemiology ; Patient Readmission ; Ischemic Stroke ; Medicare ; Stroke/epidemiology ; Stroke/drug therapy ; Risk Factors ; Sepsis ; Retrospective Studies ; Databases, Factual
    Language English
    Publishing date 2023-08-03
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0289640
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  7. Article ; Online: Blood pressure variability: An emerging target for risk reduction in the setting of hypertensive emergency.

    de Havenon, Adam

    Journal of clinical hypertension (Greenwich, Conn.)

    2019  Volume 21, Issue 11, Page(s) 1693–1694

    MeSH term(s) Blood Pressure ; Blood Pressure Determination ; Humans ; Hypertension ; Hypertension, Malignant ; Risk Reduction Behavior
    Language English
    Publishing date 2019-09-25
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2077222-1
    ISSN 1751-7176 ; 1524-6175
    ISSN (online) 1751-7176
    ISSN 1524-6175
    DOI 10.1111/jch.13701
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    Zs.A 5723: Show issues Location:
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  8. Article ; Online: Advancing Secondary Stroke Prevention Strategies: Optimal Timing of Dual Antiplatelet Therapy With Cilostazol.

    Madsen, Tracy E / de Havenon, Adam

    Neurology

    2022  Volume 98, Issue 10, Page(s) 387–388

    MeSH term(s) Cilostazol/therapeutic use ; Clopidogrel ; Humans ; Platelet Aggregation Inhibitors/therapeutic use ; Secondary Prevention ; Stroke/drug therapy ; Stroke/prevention & control
    Chemical Substances Platelet Aggregation Inhibitors ; Clopidogrel (A74586SNO7) ; Cilostazol (N7Z035406B)
    Language English
    Publishing date 2022-01-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 207147-2
    ISSN 1526-632X ; 0028-3878
    ISSN (online) 1526-632X
    ISSN 0028-3878
    DOI 10.1212/WNL.0000000000200103
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  9. Article ; Online: Neighborhood Deprivation, Race, Ethnicity, and Undiagnosed Hypertension: Results From the All of Us Research Program.

    Rivier, Cyprien A / Renedo, Daniela B / Sunmonu, N Abimbola / de Havenon, Adam / Sheth, Kevin N / Falcone, Guido J

    Hypertension (Dallas, Tex. : 1979)

    2024  Volume 81, Issue 2, Page(s) e10–e12

    MeSH term(s) Humans ; Ethnicity ; Hypertension/diagnosis ; Hypertension/epidemiology ; Population Health ; Residence Characteristics ; Racial Groups
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 423736-5
    ISSN 1524-4563 ; 0194-911X ; 0362-4323
    ISSN (online) 1524-4563
    ISSN 0194-911X ; 0362-4323
    DOI 10.1161/HYPERTENSIONAHA.123.22055
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  10. Article ; Online: Imaging of Amyloid-beta-related Arteritis.

    Bangad, Aaron / Abbasi, Mehdi / Payabvash, Sam / de Havenon, Adam

    Neuroimaging clinics of North America

    2023  Volume 34, Issue 1, Page(s) 167–173

    Abstract: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder marked by the accumulation of amyloid-beta peptide (Aβ) within the leptomeninges and smaller blood vessels of the brain. CAA can be both noninflammatory and inflammatory, and the ... ...

    Abstract Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder marked by the accumulation of amyloid-beta peptide (Aβ) within the leptomeninges and smaller blood vessels of the brain. CAA can be both noninflammatory and inflammatory, and the inflammatory version includes Aβ-related angiitis (ABRA). ABRA is a vasculitis of the central nervous system related to an inflammatory response to Aβ in the vascular walls, which necessitates differentiating ABRA from noninflammatory CAA, as ABRA may require immunosuppressive treatment. MR imaging is typically the most effective imaging modality of choice to screen for these conditions, and they should be obtained at varying time points to track disease progression.
    MeSH term(s) Humans ; Amyloid beta-Peptides/metabolism ; Cerebral Amyloid Angiopathy/diagnostic imaging ; Cerebral Amyloid Angiopathy/therapy ; Vasculitis ; Brain/diagnostic imaging ; Brain/metabolism ; Arteritis
    Chemical Substances Amyloid beta-Peptides
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1314594-0
    ISSN 1557-9867 ; 1052-5149
    ISSN (online) 1557-9867
    ISSN 1052-5149
    DOI 10.1016/j.nic.2023.09.001
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