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  1. Book: Bandscheibenbedingte Erkrankungen

    Krämer, Robert

    Ursachen, Diagnose, Behandlung, Vorbeugung, Begutachtung

    2014  

    Author's details Robert Krämer
    Keywords Intervertebral Disk ; Intervertebral Disk Displacement ; Spinal Diseases ; Bandscheibenkrankheit
    Subject Bandscheibenleiden
    Language German
    Size 402 S. : Ill., graph. Darst.
    Edition 6., überarb. und aktualisierte Aufl.
    Publisher Thieme
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    Old title 5. Aufl. u.d.T. Krämer, Jürgen: Bandscheibenbedingte Erkrankungen
    HBZ-ID HT018108170
    ISBN 978-3-13-555606-2 ; 3-13-555606-9 ; 9783131571861 ; 9783131761668 ; 3131571861 ; 3131761660
    Database Catalogue ZB MED Medicine, Health

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  2. Article: The effects of peripheral hormone responses to exercise on adult hippocampal neurogenesis.

    Kraemer, Robert R / Kraemer, Bradley R

    Frontiers in endocrinology

    2023  Volume 14, Page(s) 1202349

    Abstract: Over the last decade, a considerable amount of new data have revealed the beneficial effects of exercise on hippocampal neurogenesis and the maintenance or improvement of cognitive function. Investigations with animal models, as well as human studies, ... ...

    Abstract Over the last decade, a considerable amount of new data have revealed the beneficial effects of exercise on hippocampal neurogenesis and the maintenance or improvement of cognitive function. Investigations with animal models, as well as human studies, have yielded novel understanding of the mechanisms through which endocrine signaling can stimulate neurogenesis, as well as the effects of exercise on acute and/or chronic levels of these circulating hormones. Considering the effects of aging on the decline of specific endocrine factors that affect brain health, insights in this area of research are particularly important. In this review, we discuss how different forms of exercise influence the peripheral production of specific endocrine factors, with particular emphasis on brain-derived neurotrophic factor, growth hormone, insulin-like growth factor-1, ghrelin, estrogen, testosterone, irisin, vascular endothelial growth factor, erythropoietin, and cortisol. We also describe mechanisms through which these endocrine responses to exercise induce cellular changes that increase hippocampal neurogenesis and improve cognitive function.
    MeSH term(s) Adult ; Animals ; Humans ; Vascular Endothelial Growth Factor A ; Exercise/physiology ; Hydrocortisone ; Hippocampus/physiology ; Neurogenesis
    Chemical Substances Vascular Endothelial Growth Factor A ; Hydrocortisone (WI4X0X7BPJ)
    Language English
    Publishing date 2023-11-24
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1202349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Die lumbale Spinalkanalstenose

    Krämer, Robert / Theodoridis, Theodoros / Krämer, Jürgen

    2012  

    Author's details Robert Krämer ; Theodoros Theodoridis ; Jürgen Krämer
    Keywords Lendenwirbelsäule ; Wirbelkanalstenose
    Subject Neuralkanalstenose ; Spinalkanalstenose
    Language German
    Size X, 138 S. : zahlr. Ill., 242 mm x 170 mm
    Publisher Springer
    Publishing place Berlin u.a.
    Publishing country Germany
    Document type Book
    HBZ-ID HT017068958
    ISBN 978-3-642-13842-3 ; 3-642-13842-X
    Database Catalogue ZB MED Medicine, Health

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  4. Book ; Online: Transforming Research Excellence

    McClean, Robert / Wallace, Matthew L. / Kraemer-Mbula, Erika / Tijssen, Robert

    2019  

    Abstract: Modern-day science is under great pressure. A potent mix of increasing expectations, limited resources, tensions between competition and cooperation, and the need for evidence-based funding is creating major change in how science is conducted and ... ...

    Abstract Modern-day science is under great pressure. A potent mix of increasing expectations, limited resources, tensions between competition and cooperation, and the need for evidence-based funding is creating major change in how science is conducted and perceived. Amidst this 'perfect storm' is the allure of 'research excellence', a concept that drives decisions made by universities and funders, and defines scientists' research strategies and career trajectories.But what is 'excellent' science? And how to recognise it? After decades of inquiry and debate there is still no satisfactory answer. Are we asking the wrong question? Is reality more complex, and 'excellence in science' more elusive, than many are willing to admit? And how should excellence be defined in different parts of the world, particularly in lower-income countries of the 'Global South' where science is expected to contribute to pressing development issues, despite often scarce resources? Many wonder whether the Global South is importing, with or without consenting, the flawed tools for research evaluation from North America and Europe that are not fit for purpose.This book takes a critical view of these issues, touching on conceptual issues and practical problems that inevitably emerge when 'excellence' is at the center of science systems. Emerging from the capacity-building work of the Science Granting Councils Initiative in sub-Saharan Africa, it speaks to scholars, as well as to managers and funders of research around the world. Confronting sticky problems and uncomfortable truths, the chapters contain insights and recommendations that point towards new solutions - both for the Global South and the Global North
    Keywords Science (General) ; Education (General) ; Colonies and colonization. Emigration and immigration. International migration
    Size 1 electronic resource (296 pages)
    Publisher African Minds
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020395040
    ISBN 9781928502067 ; 1928502067
    DOI 10.5281/zenodo.3603818
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Book ; Thesis: Kapilläre Mikrozirkulationsmessung der Achillessehne mittels kombinierter Laser-Doppler-Spektrophotometrie

    Krämer, Robert

    2006  

    Author's details vorgelegt von Robert H. Krämer
    Language German
    Size 176 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Univ., Diss., 2007
    HBZ-ID HT015338957
    Database Catalogue ZB MED Medicine, Health

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  6. Book: Wirbelsäule und Sport

    Krämer, Jürgen / Wilcke, Andreas / Krämer, Robert

    Empfehlungen von Sportarten aus orthopädischer und sportwissenschaftlicher Sicht ; mit 43 Tabellen

    2005  

    Author's details J. Krämer ; A. Wilcke ; R. Krämer
    Keywords Wirbelsäulenkrankheit ; Sportart ; Empfehlung
    Subject Wirbelsäulenerkrankung ; Wirbelsäulenbelastung
    Language German
    Size XIII, 215 S. : zahlr. Ill., graph. Darst.
    Publisher Dt. Ärzte-Verl
    Publishing place Köln
    Publishing country Germany
    Document type Book
    HBZ-ID HT013939272
    ISBN 3-7691-1198-2 ; 978-3-7691-1198-9
    Database Catalogue ZB MED Medicine, Health

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  7. Book: Mikrochirurgie der Wirbelsäule

    Krämer, Robert / Herdmann, Jörg / Krämer, Jürgen

    lumbaler Bandscheibenvorfall und Spinalkanalstenose: Indikation, Technik, Nachbehandlung ; 72 Tabellen

    2005  

    Author's details Robert Krämer ; Jörg Herdmann ; Jürgen Krämer. Unter Mitarb. von
    Keywords Bandscheibenvorfall ; Lumbale Bandscheibenkrankheit ; Mikrochirurgie ; Operationstechnik ; Wirbelkanalstenose ; Dekompression
    Subject Neuralkanalstenose ; Spinalkanalstenose ; Nucleus-pulposus-Hernie ; Bandscheibenprolaps ; Diskus-Hernie ; Operative Technik ; Chirurgisches Verfahren ; Operationsverfahren
    Language German
    Size X, 149 S. : Ill., graph. Darst.
    Publisher Thieme
    Publishing place Stuttgart u.a.
    Publishing country Germany
    Document type Book
    Note Literaturverz. S. 135 - 144
    HBZ-ID HT014193118
    ISBN 3-13-128331-9 ; 978-3-13-128331-3
    Database Catalogue ZB MED Medicine, Health

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  8. Article ; Online: The effects of separate and simultaneous upper and lower body cycling on cardiorespiratory responses in young men.

    Ryan, Jessica / Hebert, Edward P / Billiot, Kim L / Ort, Brandi N / Thomschon, Kierstin / Kraemer, Robert R

    The Journal of sports medicine and physical fitness

    2023  Volume 64, Issue 2, Page(s) 129–136

    Abstract: Background: The aim of the present study was to examine the relative cardiorespiratory and perceptual responses to upper body ergometry, lower body ergometry, and combined upper and lower body ergometry at increasing exercising intensities.: Methods: ...

    Abstract Background: The aim of the present study was to examine the relative cardiorespiratory and perceptual responses to upper body ergometry, lower body ergometry, and combined upper and lower body ergometry at increasing exercising intensities.
    Methods: Eight healthy males between 19 and 30 years of age completed three exercise sessions over seven days that included graded leg ergometry, arm ergometry, and combined arm and leg ergometry in counterbalanced fashion. During leg-only and arm-only sessions, participants exercised at workloads of 0, 32, 64, and 95 W. The combined session involved simultaneous arm and leg ergometry at 0, 32, 64, and 95 W, thus eliciting double the total power output of arm-only and leg-only sessions.
    Results: At all workloads, oxygen consumption and minute ventilation responses were greater during combined arm and leg exercise than during leg-only or arm-only exercise. However, the pattern of changes in heart rate, systolic blood pressure, rate pressure product, and rating of perceived exertion (RPE) were similar in response to arm-only and combined upper and lower body exercise, despite combined exercise involving double the workload. These cardiorespiratory and perceptual responses were significantly lower during leg-only only exercise.
    Conclusions: The results of the study add to limited research comparing physiological and perceptual responses to upper, lower, and combined upper and lower body exercise. The findings highlight heightened cardiorespiratory and perceptual responses to upper body exercise alone or in combination with lower body exercise. Training that combines upper and lower body may create higher power output and elicit greater caloric expenditure while eliciting similar cardiovascular responses as upper body only exercise at moderate and higher intensities.
    MeSH term(s) Male ; Humans ; Infant, Newborn ; Exercise/physiology ; Arm/physiology ; Leg/physiology ; Ergometry ; Oxygen Consumption/physiology ; Heart Rate ; Exercise Test
    Language English
    Publishing date 2023-10-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 410823-1
    ISSN 1827-1928 ; 0022-4707
    ISSN (online) 1827-1928
    ISSN 0022-4707
    DOI 10.23736/S0022-4707.23.15306-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Influence of Intraoperative Active and Passive Breaks in Simulated Minimally Invasive Procedures on Surgeons' Perceived Discomfort, Performance, and Workload.

    Bonsch, Rosina / Seibt, Robert / Krämer, Bernhard / Rieger, Monika A / Steinhilber, Benjamin / Luger, Tessy

    Life (Basel, Switzerland)

    2024  Volume 14, Issue 4

    Abstract: Laparoscopic surgeons are at high risk of experiencing musculoskeletal discomfort, which is considered the result of long-lasting static and awkward body postures. We primarily aimed to evaluate whether passive and active work breaks can reduce ratings ... ...

    Abstract Laparoscopic surgeons are at high risk of experiencing musculoskeletal discomfort, which is considered the result of long-lasting static and awkward body postures. We primarily aimed to evaluate whether passive and active work breaks can reduce ratings of perceived discomfort among laparoscopic surgeons compared with no work breaks. We secondarily aimed to examine potential differences in performance and workload across work break conditions and requested the surgeons evaluate working with passive or active work breaks. Following a balanced, randomized cross-over design, laparoscopic surgeons performed three 90 min laparoscopic simulations without and with 2.5 min passive or active work breaks after 30 min work blocks on separate days. The simulation included the following tasks: a hot wire, peg transfer, pick-and-place, pick-and-tighten, pick-and-thread, and pull-and-stick tasks. Ratings of perceived discomfort (CR10 Borg Scale), performance per subtask, and perceived workload (NASA-TLX) were recorded, and the break interventions were evaluated (self-developed questionnaire). Statistical analyses were performed on the rating of perceived discomfort and a selection of the performance outcomes. Twenty-one participants (9F) were included, with a mean age of 36.6 years (SD 9.7) and an average experience in laparoscopies of 8.5 years (SD 5.6). Ratings of perceived musculoskeletal discomfort slightly increased over time from a mean level of 0.1 to 0.9 but did not statistically significantly differ between conditions (
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life14040426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Insights into the Decontamination of Cocaine-Positive Hair Samples.

    Erne, Robert / Baumgartner, Markus R / Kraemer, Thomas

    Journal of analytical toxicology

    2020  Volume 45, Issue 7, Page(s) 713–721

    Abstract: A highly discussed step in hair sample preparation for forensic analytics is the applied decontamination. The here presented investigations aim to gain insight and give recommendations on how to conduct this decontamination for the analysis of cocaine ... ...

    Abstract A highly discussed step in hair sample preparation for forensic analytics is the applied decontamination. The here presented investigations aim to gain insight and give recommendations on how to conduct this decontamination for the analysis of cocaine consumption in hair. Key insights were gained from the investigation of cocaine consumer hair, which was artificially contaminated in a humid atmosphere with 13C6 labelled cocaine and from cocaine powder contaminated hair. Several decontamination protocols were investigated, whereby the usage of a decontamination protocol consisting of multiple short repetitive washes allowed to visualize the wash out of (13C6-) cocaine. Multiple methanol washes proved to be an efficient and simple decontamination approach. Our findings showed that decontamination protocols can successfully wash out recent cocaine contaminations. They were observed to be rather quickly washed out, whereas cocaine from consumption or "older" cocaine contaminations were shown to eliminate both at a constant rate (from inner hair compartments). Thus, the usage of decontamination protocols to differentiate between consumption and contamination was shown to be limited. As contamination can happen any time at any level, only the application of elaborated decision trees, based on cocaine metabolite ratios and thresholds, can provide the distinction between consumption and contamination. Thus, the authors highly recommend the usage of such tools on all hair samples analyzed for cocaine consumption.
    MeSH term(s) Cocaine ; Cocaine-Related Disorders/diagnosis ; Decontamination ; Hair ; Humans ; Substance Abuse Detection
    Chemical Substances Cocaine (I5Y540LHVR)
    Language English
    Publishing date 2020-10-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 752391-9
    ISSN 1945-2403 ; 0146-4760
    ISSN (online) 1945-2403
    ISSN 0146-4760
    DOI 10.1093/jat/bkaa143
    Database MEDical Literature Analysis and Retrieval System OnLINE

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