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  1. Article ; Online: Lipomatous hypertrophy presenting as superior vena cava syndrome.

    Cheezum, Michael K / Jezior, Matthew R / Carbonaro, Salvatore / Villines, Todd C

    Journal of cardiovascular computed tomography

    2014  Volume 8, Issue 3, Page(s) 250–251

    Abstract: We report a rare case of invasive lipomatous hypertrophy of the interatrial septum presenting as superior vena cava syndrome requiring surgical resection. Lipomatous hypertrophy of the interatrial septum is a common incidental finding and is thought to ... ...

    Abstract We report a rare case of invasive lipomatous hypertrophy of the interatrial septum presenting as superior vena cava syndrome requiring surgical resection. Lipomatous hypertrophy of the interatrial septum is a common incidental finding and is thought to be a relatively benign condition. Classically, its appearance on cardiac computed tomography is primarily fatty with low attenuation, sharp margins and minimal enhancement, involving the interatrial septum with relative sparing of the fossa ovalis. In masses of unclear etiology or in rare, extensive cases resulting in cavity obstruction, such as ours, cardiac computed tomography provides complementary information to define tumor extent and characterize classic mass features facilitating diagnosis and management.
    MeSH term(s) Aged, 80 and over ; Female ; Heart Septum/diagnostic imaging ; Humans ; Hypertrophy/diagnostic imaging ; Incidental Findings ; Lipomatosis/diagnostic imaging ; Superior Vena Cava Syndrome/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2014-05
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2394360-9
    ISSN 1876-861X ; 1934-5925
    ISSN (online) 1876-861X
    ISSN 1934-5925
    DOI 10.1016/j.jcct.2014.04.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Letter regarding article by Newby et al, "Long-term adherence to evidence-based secondary prevention therapies in coronary artery disease".

    Jezior, Matthew R / Sullenberger, Lance E

    Circulation

    2006  Volume 114, Issue 6, Page(s) e240; author reply e241

    MeSH term(s) Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Cardiac Output, Low/drug therapy ; Cardiac Output, Low/physiopathology ; Coronary Artery Disease/drug therapy ; Coronary Artery Disease/physiopathology ; Coronary Artery Disease/prevention & control ; Guideline Adherence/statistics & numerical data ; Humans ; Stroke Volume/physiology ; Systole/physiology ; Time Factors
    Chemical Substances Angiotensin-Converting Enzyme Inhibitors
    Language English
    Publishing date 2006-08-08
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.106.615393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Exercise-induced atrioventricular block: a report of 2 cases and review of the literature.

    Hemann, Brian A / Jezior, Matthew R / Atwood, J Edwin

    Journal of cardiopulmonary rehabilitation

    2006  Volume 26, Issue 5, Page(s) 314–318

    MeSH term(s) Aged ; Electrocardiography ; Exercise ; Exercise Test ; Female ; Heart Block/physiopathology ; Heart Block/therapy ; Heart Conduction System/physiopathology ; Heart Conduction System/surgery ; Heart Rate ; Humans ; Male ; Myocardial Reperfusion ; Pacemaker, Artificial
    Language English
    Publishing date 2006-09-23
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 632679-1
    ISSN 0883-9212 ; 0275-1429
    ISSN 0883-9212 ; 0275-1429
    DOI 10.1097/00008483-200609000-00007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Exercise testing in Wolff-Parkinson-White syndrome: case report with ECG and literature review.

    Jezior, Matthew R / Kent, Steven M / Atwood, J Edwin

    Chest

    2005  Volume 127, Issue 4, Page(s) 1454–1457

    Abstract: ECG changes during exercise stress testing, such as false-positive ST-segment depression and disappearance of the delta wave, are reported in patients with the Wolff-Parkinson-White (WPW) pattern. We present a case of exercise testing in a 53-year-old ... ...

    Abstract ECG changes during exercise stress testing, such as false-positive ST-segment depression and disappearance of the delta wave, are reported in patients with the Wolff-Parkinson-White (WPW) pattern. We present a case of exercise testing in a 53-year-old man with WPW syndrome with ischemic-appearing ECG changes and normal nuclear stress perfusion study findings who was thought to be at clinically low risk for having significant coronary disease. A literature review is discussed. Although ST-segment depression typical for ischemia occurs in half of the patients in whom WPW syndrome is reported, exercise testing is still an important tool in their evaluation. Data other than ECG response can be interpreted in the context of clinical history and physical examination findings to stratify the risk of coronary disease. Complete and sudden disappearance of the delta wave has been seen during exercise in 20% of patients with WPW syndrome and can identify those who are at low risk for sudden arrhythmic death.
    MeSH term(s) Electrocardiography ; Exercise Test ; Humans ; Male ; Middle Aged ; Wolff-Parkinson-White Syndrome/physiopathology
    Language English
    Publishing date 2005-04
    Publishing country United States
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 1032552-9
    ISSN 1931-3543 ; 0012-3692
    ISSN (online) 1931-3543
    ISSN 0012-3692
    DOI 10.1378/chest.127.4.1454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A randomized trial of the effects of rosiglitazone and metformin on inflammation and subclinical atherosclerosis in patients with type 2 diabetes.

    Stocker, Derek J / Taylor, Allen J / Langley, Roy W / Jezior, Matthew R / Vigersky, Robert A

    American heart journal

    2007  Volume 153, Issue 3, Page(s) 445.e1–6

    Abstract: ... in a multivariable model controlling for changes in HbA1c and lipid parameters (r = .31; P = .01).: Conclusions ...

    Abstract Background: Metformin and rosiglitazone both improve glycemic control in type 2 diabetes mellitus, however may possess different anti-inflammatory and anti-atherosclerotic properties. We investigated the effects of these medications on high-sensitivity C-reactive protein (hsCRP) and carotid artery intima-media thickness (CIMT) to determine their relative potential to reduce cardiovascular risk independent of their antihyperglycemic actions.
    Methods: Ninety-two subjects with suboptimally controlled diabetes mellitus (hemoglobin A1c [HbA1c] >7.0%) were assigned to therapy with either rosiglitazone 4 mg once daily or metformin 850 mg twice daily for 24 weeks. The primary end point was the change in hsCRP after 24 weeks. The change in CIMT was prespecified as a secondary end point.
    Results: Metformin and rosiglitazone treatment led to similar significant improvements in glycemic control (HbA1c -1.08% in the rosiglitazone group and -1.18% in the metformin group, P = nonsignificant). High-sensitivity C-reactive protein levels decreased by an average of 68% in the rosiglitazone group (5.99 +/- 0.88 to 1.91 +/- 0.28 mg/L, P < .001), compared with a nonsignificant 4% reduction in hsCRP with metformin (5.69 +/- 0.83 to 5.46 +/- 0.92 mg/L; P = nonsignificant). Maximal CIMT progressed in the metformin group (+0.084 +/- 0.038 mm), whereas regression of maximal CIMT was observed in the rosiglitazone group (-0.037 +/- 0.031 mm; P = .02 for the between group comparison). Similar changes were observed for mean CIMT. The change in hsCRP and maximal CIMT were related in a multivariable model controlling for changes in HbA1c and lipid parameters (r = .31; P = .01).
    Conclusions: Rosiglitazone, compared to metformin, induced a prompt and profound reduction in hsCRP levels independent of its effect on glycemia. This change was associated with regression of CIMT after 24 weeks.
    MeSH term(s) Aged ; Atherosclerosis/drug therapy ; C-Reactive Protein/analysis ; Diabetes Mellitus, Type 2/drug therapy ; Diabetic Angiopathies/drug therapy ; Disease Progression ; Female ; Humans ; Hypoglycemic Agents/administration & dosage ; Hypoglycemic Agents/therapeutic use ; Inflammation/drug therapy ; Male ; Metformin/administration & dosage ; Metformin/therapeutic use ; Middle Aged ; Multivariate Analysis ; Thiazolidinediones/administration & dosage ; Thiazolidinediones/therapeutic use ; Tunica Intima/drug effects ; Tunica Intima/pathology ; Tunica Media/drug effects ; Tunica Media/pathology ; Vasodilator Agents/administration & dosage ; Vasodilator Agents/therapeutic use
    Chemical Substances Hypoglycemic Agents ; Thiazolidinediones ; Vasodilator Agents ; rosiglitazone (05V02F2KDG) ; C-Reactive Protein (9007-41-4) ; Metformin (9100L32L2N)
    Language English
    Publishing date 2007-03
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 80026-0
    ISSN 1097-6744 ; 0002-8703
    ISSN (online) 1097-6744
    ISSN 0002-8703
    DOI 10.1016/j.ahj.2006.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Wartime burn care in Iraq: 28th Combat Support Hospital, 2003.

    Stout, Louis R / Jezior, James R / Melton, Lisette P / Walker, Joy A / Brengman, Matthew L / Neumeier, Sonia T / Smith, Robin L / Vanfosson, Christopher A / Knuth, Thomas E / Holcomb, John B / Cancio, Leopoldo C

    Military medicine

    2007  Volume 172, Issue 11, Page(s) 1148–1153

    Abstract: Introduction: The U.S. Army 28th Combat Support Hospital (CSH), an echelon III facility, deployed to Iraq at the start of military operations in 2003. Shortly after arrival, it was designated as the hospital primarily responsible for burn care for the U. ...

    Abstract Introduction: The U.S. Army 28th Combat Support Hospital (CSH), an echelon III facility, deployed to Iraq at the start of military operations in 2003. Shortly after arrival, it was designated as the hospital primarily responsible for burn care for the U.S. military in Iraq. This report reviews the experience of the CSH with burn care during combat operations.
    Methods: An after-action review was conducted during a 2-day period after the hospital's redeployment.
    Results: Between April 11, 2003, and August 21, 2003, the 28th CSH treated a total of 7,920 patients, of whom 103 (1.3%) had burns. Patients included U.S. and allied service members, U.S. contractors, and Iraqi prisoners of war and civilians. Although a CSH is designed to care for patients until they can be stabilized and evacuated, usually within 1 to 3 days, the length of stay for some Iraqi patients was as long as 53 days. Definitive care, including excision and grafting of the burn wound, was thus required for some Iraqi patients. The largest graft completed comprised 40% of the total body surface area. The largest burn survived involved approximately 65% of the total body surface area. Eighteen (17%) of 103 patients returned to duty after treatment at the 28th CSH. The mortality rate for burn patients at the 28th CSH was 8%. Shortages of burn-experienced personnel and burn-specific supplies were identified during the after-action review.
    Conclusions: The CSH provided complex definitive care to burn patients in an austere environment. Predeployment identification of military field hospitals for such specialized missions, with early assignment of experienced personnel and materiel to these units, may improve future wartime burn care.
    MeSH term(s) Acute Disease ; Burns/therapy ; Emergency Medical Services ; Hospitals, Military ; Humans ; Iraq ; Military Medicine ; Military Personnel ; Retrospective Studies ; Triage ; United States ; Warfare
    Language English
    Publishing date 2007-11-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.7205/milmed.172.11.1148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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